Pharmacological activation of constitutive androstane receptor induces female-specific modulation of hepatic metabolism

Authors: Marine Huillet, Frédéric Lasserre, Marie-Pierre Gratacap, Beatrice Engelmann, Justine Bruse, Arnaud Polizzi, Tiffany Fougeray, Céline Marie Pauline Martin, Clémence Rives, Anne Fougerat, Claire Naylies, Yannick Lippi, Géraldine Garcia, Elodie Rousseau-Bacquie, Cécile Canlet, Laurent Debrauwer, Ulrike Rolle-Kampczyk, Martin von Bergen, Bernard Payrastre, Elisa Boutet-Robinet, Laurence Gamet-Payrastre, Hervé Guillou, Nicolas Loiseau, Sandrine Ellero-Simatos

Source: JHEP Reports, Vol 6, Iss 1, Pp 100930- (2024)

Subject Terms: Sexual dimorphism, Hepatic xenobiotic metabolism, Lipoprotein metabolism, Platelet aggregation, Trimethylamine-N-oxide, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923002616; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/17ee943087754a249afd56b554637a6c

Dual-Hit: Glyphosate exposure at NOAEL level negatively impacts birth and glia-behavioural measures in heterozygous shank3 mutants

Authors: Sophie Sakkaki, Noemie Cresto, Raphaël Chancel, Maé Jaulmes, Emma Zub, Marine Blaquière, Pierre Sicard, Tangui Maurice, Sandrine Ellero-Simatos, Laurence Gamet-Payrastre, Nicola Marchi, Julie Perroy

Source: Environment International, Vol 180, Iss , Pp 108201- (2023)

Subject Terms: NOAEL-Glyphosate, Shank3 mutation, Perinatal exposure, Environmental contamination, Genetic predisposition, Neuroinflammation, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412023004749; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/ec621fdd13bc4c01a42a4701c968b3eb

Prospective association between dietary pesticide exposure profiles and type 2 diabetes risk in the NutriNet-Santé cohort

Authors: Pauline Rebouillat, Rodolphe Vidal, Jean-Pierre Cravedi, Bruno Taupier-Letage, Laurent Debrauwer, Laurence Gamet-Payrastre, Hervé Guillou, Mathilde Touvier, Léopold K. Fezeu, Serge Hercberg, Denis Lairon, Julia Baudry, Emmanuelle Kesse-Guyot

Source: Environmental Health, Vol 21, Iss 1, Pp 1-15 (2022)

Subject Terms: Dietary exposure, Pesticides, Organic farming, Epidemiology, Type 2 diabetes, Environmental health, Industrial medicine. Industrial hygiene, RC963-969, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1476-069X

Access URL: https://doaj.org/article/f411f1f0624a4fbabbb18a6bf1719ce0

The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice

Authors: Sharon Ann Barretto, Frederic Lasserre, Marine Huillet, Marion Régnier, Arnaud Polizzi, Yannick Lippi, Anne Fougerat, Elodie Person, Sandrine Bruel, Colette Bétoulières, Claire Naylies, Céline Lukowicz, Sarra Smati, Laurence Guzylack, Maïwenn Olier, Vassilia Théodorou, Laila Mselli-Lakhal, Daniel Zalko, Walter Wahli, Nicolas Loiseau, Laurence Gamet-Payrastre, Hervé Guillou, Sandrine Ellero-Simatos

Source: Microbiome, Vol 9, Iss 1, Pp 1-16 (2021)

Subject Terms: Gut microbiota, Liver, Pregnane X receptor, NR1I2, Xenobiotic metabolism, Fatty acid metabolism, Microbial ecology, QR100-130

File Description: electronic resource

Relation: https://doaj.org/toc/2049-2618

Access URL: https://doaj.org/article/12bed86311cd49f3af2cf456cbbcc32d

Perinatal exposure to a dietary pesticide cocktail does not increase susceptibility to high-fat diet-induced metabolic perturbations at adulthood but modifies urinary and fecal metabolic fingerprints in C57Bl6/J mice

Authors: Lorraine Smith, Wendy Klément, Léonie Dopavogui, Frédéric de Bock, Frédéric Lasserre, Sharon Barretto, Céline Lukowicz, Anne Fougerat, Arnaud Polizzi, Benoist Schaal, Bruno Patris, Colette Denis, Guylène Feuillet, Cécile Canlet, Emilien L Jamin, Laurent Debrauwer, Laila Mselli-Lakhal, Nicolas Loiseau, Hervé Guillou, Nicola Marchi, Sandrine Ellero-Simatos, Laurence Gamet-Payrastre

Source: Environment International, Vol 144, Iss , Pp 106010- (2020)

Subject Terms: Pesticide cocktail, Metabolism, Perinatal, Metabolomics, Dietary exposure, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412020319656; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/d7d9d1d5d2174beca38b3540364e88a2

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

Authors: Clémence Rives, Anne Fougerat, Sandrine Ellero-Simatos, Nicolas Loiseau, Hervé Guillou, Laurence Gamet-Payrastre, Walter Wahli

Source: Biomolecules, Vol 10, Iss 12, p 1702 (2020)

Subject Terms: steatosis, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), food contaminant, macronutrients, micronutrients, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/10/12/1702; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/ea40c45da71f4d2c85a2f82ec61dd434

In vitro impact of five pesticides alone or in combination on human intestinal cell line Caco-2

Authors: Sylvain Ilboudo, Edwin Fouche, Virginie Rizzati, Adama M. Toé, Laurence Gamet-Payrastre, Pierre I. Guissou

Source: Toxicology Reports, Vol 1, Iss C, Pp 474-489 (2014)

Subject Terms: Pesticide, Mixture, Caco-2, Oxidative stress, Locust control, Antioxidant, Cell signaling, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750014000535; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/e275196463da446aa9b93195042fa1ab

Specific Metabolic Fingerprint of a Dietary Exposure to a Very Low Dose of Endosulfan

Authors: Cécile Canlet, Marie Tremblay-Franco, Roselyne Gautier, Jérôme Molina, Benjamin Métais, Florence Blas-Y Estrada, Laurence Gamet-Payrastre

Source: Journal of Toxicology, Vol 2013 (2013)

Subject Terms: Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1687-8191; https://doaj.org/toc/1687-8205

Access URL: https://doaj.org/article/945d96ce36544004be9f04b0f804a96d