An AMBRA1, ULK1 and PP2A regulatory network regulates cytotoxic T cell differentiation via TFEB activation

Authors: Loredana Migliore, Valentina Cianfanelli, Fabrizia Zevolini, Monica Gesualdo, Leandro Marzuoli, Laura Patrussi, Cristina Ulivieri, Giuseppe Marotta, Francesco Cecconi, Francesca Finetti, Cosima T. Baldari

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: AMBRA1, Cytotoxic T cell, Lytic granule, PP2A / ULK1, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/97df8924a79e49b38eb383c0f7a79b79

Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy

Authors: Ludovica Lopresti, Vanessa Tatangelo, Cosima T. Baldari, Laura Patrussi

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: tumor microenvironment, cytokine, interleukin, T cell suppression, cytotoxic T lymphocyte, TIL, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1418527/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/196d4c4dcb614399ba338e50e5859c38

Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia

Authors: Gioia Boncompagni, Vanessa Tatangelo, Ludovica Lopresti, Cristina Ulivieri, Nagaja Capitani, Carmela Tangredi, Francesca Finetti, Giuseppe Marotta, Federica Frezzato, Andrea Visentin, Sara Ciofini, Alessandro Gozzetti, Monica Bocchia, Diego Calzada-Fraile, Noa B. Martin Cofreces, Livio Trentin, Laura Patrussi, Cosima T. Baldari

Source: Cell Death and Disease, Vol 15, Iss 2, Pp 1-13 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/d642398d0f0d48b38f301e377350c763

p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation

Authors: Ludovica Lopresti, Nagaja Capitani, Vanessa Tatangelo, Carmela Tangredi, Gioia Boncompagni, Federica Frezzato, Andrea Visentin, Giuseppe Marotta, Sara Ciofini, Alessandro Gozzetti, Monica Bocchia, Livio Trentin, Cosima T. Baldari, Laura Patrussi

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Subject Terms: PD-L1, immune checkpoint, CLL, p66Shc, immune synapse, ROS, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1297116/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/e7e9e6a473054becbee4aeecfc465039

p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB

Authors: Vanessa Tatangelo, Gioia Boncompagni, Nagaja Capitani, Ludovica Lopresti, Noemi Manganaro, Federica Frezzato, Andrea Visentin, Livio Trentin, Cosima T. Baldari, Laura Patrussi

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: NF-kB, chronic lymphocytic leukemia (CLL), P66shc, ROS, chemokine receptor, CCR2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.877495/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a5a1f6b65d6b4a1ea89584dc82c6e24d

Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation

Authors: Gioia Boncompagni, Alessia Varone, Vanessa Tatangelo, Nagaja Capitani, Federica Frezzato, Andrea Visentin, Livio Trentin, Daniela Corda, Cosima T. Baldari, Laura Patrussi

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: CLL, apoptosis, Bax, glycerophosphoinositol, SHP-1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.835290/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/ecef887653664fcd9795e727d12332b6

Fetal Myocardial Expression of GLUT1: Roles of BPA Exposure and Cord Blood Exosomes in a Rat Model

Authors: Leonardo Ermini, Maurizio Mandalà, Laura Cresti, Sofia Passaponti, Laura Patrussi, Luana Paulesu, Kent Thornburg, Francesca Ietta

Source: Cells, Vol 11, Iss 20, p 3195 (2022)

Subject Terms: BPA, exosomes, placenta, fetal heart, GLUT1, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/20/3195; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/41898c1e17974313921fec637df0c485

LMW-PTP targeting potentiates the effects of drugs used in chronic lymphocytic leukemia therapy

Authors: Nagaja Capitani, Giulia Lori, Paolo Paoli, Laura Patrussi, Arianna Troilo, Cosima T. Baldari, Giovanni Raugei, Mario Milco D’Elios

Source: Cancer Cell International, Vol 19, Iss 1, Pp 1-9 (2019)

Subject Terms: Morin, Chronic lymphocytic leukemia, Apoptosis, LMW-PTP, Migration, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12935-019-0786-1; https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/2fa005b166fa4a7e8e0f106849b356c3

Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays

Authors: Francesca Finetti, Nagaja Capitani, Noemi Manganaro, Vanessa Tatangelo, Francesca Libonati, Giulia Panattoni, Ivo Calaresu, Laura Ballerini, Cosima T. Baldari, Laura Patrussi

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: organotypic culture, spleen, vibratome, precision-cut, white pulp, red pulp, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00471/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2b433c885a91459f83940c0e93234e6d

p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape

Authors: Laura Patrussi, Nagaja Capitani, Cristina Ulivieri, Noemi Manganaro, Massimo Granai, Francesca Cattaneo, Anna Kabanova, Lucia Mundo, Stefania Gobessi, Federica Frezzato, Andrea Visentin, Francesca Finetti, Pier Giuseppe Pelicci, Mario M. D’Elios, Livio Trentin, Gianpietro Semenzato, Lorenzo Leoncini, Dimitar G. Efremov, Cosima T. Baldari

Source: Haematologica, Vol 104, Iss 10 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9087; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/6bc4cda3fc2a4cd2a79acd0bbd87ceab