Targeting NLRP3 inhibits AML progression by inducing PERK/eIF2-mediated apoptosis

Authors: Michela Luciano, Helene Sieberer, Peter W. Krenn, Hieu-Hoa Dang, Julia Vetter, Theresa Neuper, Diana Amend, Constantin Blöchl, Christian X. Weichenberger, Anna Eglseer, Michael S. Unger, Ancuela Andosch, Philip Steiner, Daniel Neureiter, Renate Bauer, Laura Hummer, Suzana Tesanovic, Stephanie Binder, Dominik P. Elmer, Helen Strandt, Susanne Schaller, Dirk Strunk, Lisa Pleyer, Richard Greil, Stephan Winkler, Tanja N. Hartmann, Dirk Schmidt-Arras, Christian G. Huber, Fritz Aberger, Jutta Horejs-Hoeck

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)

Subject Terms: Acute myeloid leukemia, Apoptosis, eIF2α, NLRP3, PERK, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/4d77e7ab0fdf4883bc818ffc7dd4f0d8

Sildenafil Versus Placebo for Early Pulmonary Vascular Disease in Scleroderma (SEPVADIS): protocol for a randomized controlled trial

Authors: Matthew R. Lammi, Monica Mukherjee, Lesley Ann Saketkoo, Kyle Carey, Laura Hummers, Steven Hsu, Amita Krishnan, Marie Sandi, Ami A. Shah, Stefan L. Zimmerman, Paul M. Hassoun, Steven C. Mathai

Source: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024)

Subject Terms: Pulmonary hypertension, Scleroderma, Systemic sclerosis, Clinical trial, Sildenafil, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/cc9d87139ffa435ebf2a6aa88618e7c9

Serum uric acid as a marker of disease risk, severity, and survival in systemic sclerosis-related pulmonary arterial hypertension

Authors: Catherine E. Simpson, Rachel L. Damico, Laura Hummers, Rubina M. Khair, Todd M. Kolb, Paul M. Hassoun, Stephen C. Mathai

Source: Pulmonary Circulation, Vol 9 (2019)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8940

Access URL: https://doaj.org/article/481d8af0a9f84c97b12d1c8fcaa09187

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Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Authors: Chris Cheadle, Alan E Berger, Stephen C Mathai, Dmitry N Grigoryev, Tonya N Watkins, Yumiko Sugawara, Sangjucta Barkataki, Jinshui Fan, Meher Boorgula, Laura Hummers, Ari L Zaiman, Reda Girgis, Michael A McDevitt, Roger A Johns, Frederick Wigley, Kathleen C Barnes, Paul M Hassoun

Source: PLoS ONE, Vol 7, Iss 4, p e34951 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3335832?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/10f0172ce73240efb638308f089a07da

Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice.

Authors: Xialin Liu, Shoukang Zhu, Tao Wang, Laura Hummers, Fredrick M Wigley, Pascal J Goldschmidt-Clermont, Chunming Dong

Source: PLoS Medicine, Vol 2, Iss 12, p e354 (2005)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC1274282?pdf=render; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/fd98e27e1fd94b2a9c718e5c1bb50fa3