Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics

Authors: James Wang, Jai Woong Seo, Aris J. Kare, Martin Schneider, Mallesh Pandrala, Spencer K. Tumbale, Marina N. Raie, Gokce Engudar, Nisi Zhang, Yutong Guo, Xiaoxu Zhong, Sofia Ferreira, Bo Wu, Laura D. Attardi, Guillem Pratx, Andrei Iagaru, Ryan L. Brunsing, Gregory W. Charville, Walter G. Park, Katherine W. Ferrara

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/850758b6ae8142a994479d392a5302d0

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

Authors: Clara Morral, Arshad Ayyaz, Hsuan-Cheng Kuo, Mardi Fink, Ioannis I. Verginadis, Andrea R. Daniel, Danielle N. Burner, Lucy M. Driver, Sloane Satow, Stephanie Hasapis, Reem Ghinnagow, Lixia Luo, Yan Ma, Laura D. Attardi, Constantinos Koumenis, Andy J. Minn, Jeffrey L. Wrana, Chang-Lung Lee, David G. Kirsch

Source: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f8259dde53cf4c8bad036795c5ff982c

Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state

Authors: Bo He, Lauren Stoffel, Clifford Jiajun He, Kumsun Cho, Albert M. Li, Haowen Jiang, Brittany M. Flowers, Kha The Nguyen, Kelly Wen Wang, Audrey Yixin Zhao, Meng-Ning Zhou, Sofia Ferreira, Laura D. Attardi, Jiangbin Ye

Source: Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/49624cfd032446e1b3b7c7e99edf32b1

The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling

Authors: Eui Jung Moon, Stephano S. Mello, Caiyun G. Li, Jen-Tsan Chi, Kaushik Thakkar, Jacob G. Kirkland, Edward L. Lagory, Ik Jae Lee, Anh N. Diep, Yu Miao, Marjan Rafat, Marta Vilalta, Laura Castellini, Adam J. Krieg, Edward E. Graves, Laura D. Attardi, Amato J. Giaccia

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/74a0bdf041f848a69bf653962a2ec1b4

SIDT2 RNA Transporter Promotes Lung and Gastrointestinal Tumor Development

Authors: Tan A. Nguyen, Kathryn T. Bieging-Rolett, Tracy L. Putoczki, Ian P. Wicks, Laura D. Attardi, Ken C. Pang

Source: iScience, Vol 20, Iss , Pp 14-24 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004219303463; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/6849ae9ab80943549e7585a2addeaeec

Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I

Authors: Natalia Gomez-Ospina, Samantha G. Scharenberg, Nathalie Mostrel, Rasmus O. Bak, Sruthi Mantri, Rolen M. Quadros, Channabasavaiah B. Gurumurthy, Ciaran Lee, Gang Bao, Carlos J. Suarez, Shaukat Khan, Kazuki Sawamoto, Shunji Tomatsu, Nitin Raj, Laura D. Attardi, Laure Aurelian, Matthew H. Porteus

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/8f066f14a98c44ea90d2d9109e701772

Zmat3 splices together p53-dependent tumor suppression

Authors: Kathryn T. Bieging-Rolett, Laura D. Attardi

Source: Molecular & Cellular Oncology, Vol 8, Iss 3 (2021)

Subject Terms: p53, zmat3, tumor suppression, splicing, crispr screen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2372-3556

Access URL: https://doaj.org/article/b7744515a0904af087fdd07d770d8420

P53 orchestrates a complex symphony of cellular processes during oncosuppression

Authors: Liz J. Valente, Laura D. Attardi

Source: Molecular & Cellular Oncology, Vol 8, Iss 1 (2021)

Subject Terms: p53, tumor suppression, transformation, cancer, cell biology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2372-3556

Access URL: https://doaj.org/article/97cd1f591c234a7fb3f506ccefb827f3

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

Authors: Amy Tarangelo, Leslie Magtanong, Kathryn T. Bieging-Rolett, Yang Li, Jiangbin Ye, Laura D. Attardi, Scott J. Dixon

Source: Cell Reports, Vol 22, Iss 3, Pp 569-575 (2018)

Subject Terms: p53, cell death, metabolism, cancer, ferroptosis, reactive oxygen species, glutathione, cystine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717319149; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/65fa87ec72d24c9a89ee70935269d022

Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Chd7 Mutant Mouse Ear

Authors: Robert Durruthy-Durruthy, Ethan D. Sperry, Margot E. Bowen, Laura D. Attardi, Stefan Heller, Donna M. Martin

Source: Frontiers in Genetics, Vol 9 (2018)

Subject Terms: CHD7, chromatin remodeling, inner ear development, single cell genomics, otic vesicle, mouse models, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2018.00473/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/8827bb90b6e24226bf46d7c43617fe3f

Analysis of p53 Transactivation Domain Mutants Reveals Acad11 as a Metabolic Target Important for p53 Pro-Survival Function

Authors: Dadi Jiang, Edward L. LaGory, Daniela Kenzelmann Brož, Kathryn T. Bieging, Colleen A. Brady, Nichole Link, John M. Abrams, Amato J. Giaccia, Laura D. Attardi

Source: Cell Reports, Vol 10, Iss 7, Pp 1096-1109 (2015)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124715000686; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/83a777ee595942b28dbf89a26e4abbef

Loss of the Desmosomal Component Perp Impairs Wound Healing In Vivo

Authors: Veronica G. Beaudry, Rebecca A. Ihrie, Suzanne B. R. Jacobs, Bichchau Nguyen, Navneeta Pathak, Eunice Park, Laura D. Attardi

Source: Dermatology Research and Practice, Vol 2010 (2010)

Subject Terms: Dermatology, RL1-803

File Description: electronic resource

Relation: https://doaj.org/toc/1687-6105; https://doaj.org/toc/1687-6113

Access URL: https://doaj.org/article/16657c900fef40eb80e337e43439dd06

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Unimpaired skin carcinogenesis in Desmoglein 3 knockout mice.

Authors: Sylvain Baron, Anabel Hoang, Hannes Vogel, Laura D Attardi

Source: PLoS ONE, Vol 7, Iss 11, p e50024 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3503716?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dc4f7a835ec244cea3afc46d95b645d7

Loss of the p53/p63 regulated desmosomal protein Perp promotes tumorigenesis.

Authors: Veronica G Beaudry, Dadi Jiang, Rachel L Dusek, Eunice J Park, Stevan Knezevich, Katie Ridd, Hannes Vogel, Boris C Bastian, Laura D Attardi

Source: PLoS Genetics, Vol 6, Iss 10, p e1001168 (2010)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2958815?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/693419627b644e96adabff8564c09e92

Developmental context determines latency of MYC-induced tumorigenesis.

Authors: Shelly Beer, Anders Zetterberg, Rebecca A Ihrie, Ryan A McTaggart, Qiwei Yang, Nicole Bradon, Constadina Arvanitis, Laura D Attardi, Sandy Feng, Boris Ruebner, Robert D Cardiff, Dean W Felsher

Source: PLoS Biology, Vol 2, Iss 11, p e332 (2004)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC519000?pdf=render; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/da0a6891f4844b24ad898e2a6697d513