Early therapeutic drug monitoring of methotrexate and its association with acute kidney injury: A retrospective cohort study

Authors: Nicolás Tentoni, Miriam Hwang, Gabriela Villanueva, Ryan Combs, Jennifer Lowe, Laura B. Ramsey, Zachary L. Taylor, Thais Murciano Carrillo, María Dolores Aumente, Teresa López‐Viñau López, Carmelo Rizzari, Scott C. Howard

Source: Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)

Subject Terms: acute kidney injury, biomarker, early methotrexate elimination half‐life, high‐dose methotrexate, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/e36aebfabb7e428d82a45f18aff48572

Clinical covariates that improve the description of high dose methotrexate pharmacokinetics in a diverse population to inform MTXPK.org

Authors: Zachary L. Taylor, Tamara P. Miller, Ethan A. Poweleit, Nicholas P. DeGroote, Lauren Pommert, Oluwafunbi Awoniyi, Sarah G. Board, Ngozi Ugboh, Vivek Joshi, Nick Ambrosino, Ashley Chavana, Melanie B. Bernhardt, Eric S. Schafer, Maureen M. O'Brien, Sharon M. Castellino, Laura B. Ramsey

Source: Clinical and Translational Science, Vol 16, Iss 11, Pp 2130-2143 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/5f03661676c74213b95f1b9c76080e52

Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients

Authors: Alaa Alghamdi, Sarah Seay, David K. Hooper, Charles D. Varnell Jr., Leanna Darland, Tomoyuki Mizuno, Danielle Lazear, Laura B. Ramsey

Source: Clinical and Translational Science, Vol 16, Iss 10, Pp 1768-1778 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/c5b65281830b47ccb11837040ef4f486

Pharmacogenetic testing in primary care could bolster depression treatment: A value proposition

Authors: Nina R. Sperber, Megan C. Roberts, Sarah Gonzales, Lisa M. Bendz, Deborah Cragun, Susanne B. Haga, R. Ryanne Wu, Chioma Omeogu, Brystana Kaufman, Natasha J. Petry, Laura B. Ramsey, Ryley Uber

Source: Clinical and Translational Science, Vol 17, Iss 6, Pp n/a-n/a (2024)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/215c0e7431aa4391bbd57f55626e2b0b

84 Using Opportunistic Sampling and Remnant Blood Samples to Develop Pediatric Pharmacokinetic Models to Inform Antidepressant Dosing

Authors: Jeffrey R. Strawn, Ethan A. Poweleit, Zachary L. Taylor, Tomoyuki Mizuno, Samuel Vaughn, Zeruesenay Desta, Stephani Stancil, Laura B. Ramsey

Source: Journal of Clinical and Translational Science, Vol 8, Pp 22-23 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.cambridge.org/core/product/identifier/S2059866124000840/type/journal_article; https://doaj.org/toc/2059-8661

Access URL: https://doaj.org/article/e1d8503c9362423ea58b12fa2f44074f

Best–worst scaling methodology to evaluate constructs of the Consolidated Framework for Implementation Research: application to the implementation of pharmacogenetic testing for antidepressant therapy

Authors: Ramzi G. Salloum, Jeffrey R. Bishop, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Sony Tuteja

Source: Implementation Science Communications, Vol 3, Iss 1, Pp 1-9 (2022)

Subject Terms: Best–worst scaling, Pharmacogenetic testing, Consolidated Framework for Implementation Research, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2662-2211

Access URL: https://doaj.org/article/622e160da30149b7bb83516b31e629d0

Influence of CYP2D6 metabolizer status on ondansetron efficacy in pediatric patients undergoing hematopoietic stem cell transplantation: A case series

Authors: Andrea Edwards, Ashley Teusink‐Cross, Lisa J. Martin, Cynthia A. Prows, Parinda A. Mehta, Laura B. Ramsey

Source: Clinical and Translational Science, Vol 15, Iss 3, Pp 610-618 (2022)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/049767258135467290e37ec23abfcaba

Multisite evaluation of institutional processes and implementation determinants for pharmacogenetic testing to guide antidepressant therapy

Authors: Sony Tuteja, Ramzi G. Salloum, Amanda L. Elchynski, D. Max Smith, Elizabeth Rowe, Kathryn V. Blake, Nita A. Limdi, Christina L. Aquilante, Jill Bates, Amber L. Beitelshees, Amber Cipriani, Benjamin Q. Duong, Philip E. Empey, Christine M. Formea, J. Kevin Hicks, Pawel Mroz, David Oslin, Amy L. Pasternak, Natasha Petry, Laura B. Ramsey, Allyson Schlichte, Sandra M. Swain, Kristen M. Ward, Kristin Wiisanen, Todd C. Skaar, Sara L. Van Driest, Larisa H. Cavallari, Jeffrey R. Bishop, for the IGNITE Pharmacogenetics Working Group

Source: Clinical and Translational Science, Vol 15, Iss 2, Pp 371-383 (2022)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/8db7d4a68b104a13ba4ac33d91a1855f

SLCO1B1 *15 allele is associated with methotrexate‐induced nausea in pediatric patients with inflammatory bowel disease

Authors: Rishi S. Mehta, Zachary L. Taylor, Lisa J. Martin, Michael J. Rosen, Laura B. Ramsey

Source: Clinical and Translational Science, Vol 15, Iss 1, Pp 63-69 (2022)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/7312e4e443344c46acccaabfd37284d5

Toward pharmacogenetic SLCO1B1‐guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model

Authors: Zachary L. Taylor, Lauren E. Thompson, Heather Bear, Tomoyuki Mizuno, Alexander A. Vinks, Laura B. Ramsey

Source: Clinical and Translational Science, Vol 14, Iss 6, Pp 2267-2277 (2021)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/a6b2dde967344193adb79c03c44199eb

Characterizing Pharmacogenetic Testing Among Children’s Hospitals

Authors: Jacob T. Brown, Laura B. Ramsey, Sara L. Van Driest, Ida Aka, Susan I. Colace

Source: Clinical and Translational Science, Vol 14, Iss 2, Pp 692-701 (2021)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/c8b2cc9e26bc49a8bd6ad877ef14041e

Selective Serotonin Reuptake Inhibitor Pharmacokinetics During Pregnancy: Clinical and Research Implications

Authors: Ethan A. Poweleit, Margaret A. Cinibulk, Sarah A. Novotny, Melissa Wagner-Schuman, Laura B. Ramsey, Jeffrey R. Strawn

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: anxiety, depression, pharmacokinctics, pregnancy, SSRI (selective serotonergic reuptake inhibitors), Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.833217/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/435a8c331c964f57a118d67a2c7cbb4d

Pediatric Therapeutic Drug Monitoring for Selective Serotonin Reuptake Inhibitors

Authors: Jeffrey R. Strawn, Ethan A. Poweleit, Chakradhara Rao S. Uppugunduri, Laura B. Ramsey

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: therapeutic drug monitoring, selective serotonin reuptake inhibitor, depressive disorder, anxiety disorder, tolerability, pediatric, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.749692/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/1b09e8e8b4d64ced9e08fd0793fb7fba

Influence of CYP2C19 Metabolizer Status on Escitalopram/Citalopram Tolerability and Response in Youth With Anxiety and Depressive Disorders

Authors: Stacey L. Aldrich, Ethan A. Poweleit, Cynthia A. Prows, Lisa J. Martin, Jeffrey R. Strawn, Laura B. Ramsey

Source: Frontiers in Pharmacology, Vol 10 (2019)

Subject Terms: pharmacogenetics, CYP2C19, SSRI (selective serotonin reuptake inhibitor), antidepressant, anxiety disorders, depressive disorder, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00099/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/3923e69eeedb4f0db31d184de9441d0f

Combined Targeting of JAK2 and Bcl-2/Bcl-xL to Cure Mutant JAK2-Driven Malignancies and Overcome Acquired Resistance to JAK2 Inhibitors

Authors: Michaela Waibel, Vanessa S. Solomon, Deborah A. Knight, Rachael A. Ralli, Sang-Kyu Kim, Kellie-Marie Banks, Eva Vidacs, Clemence Virely, Keith C.S. Sia, Lauryn S. Bracken, Racquel Collins-Underwood, Christina Drenberg, Laura B. Ramsey, Sara C. Meyer, Megumi Takiguchi, Ross A. Dickins, Ross Levine, Jacques Ghysdael, Mark A. Dawson, Richard B. Lock, Charles G. Mullighan, Ricky W. Johnstone

Source: Cell Reports, Vol 5, Iss 4, Pp 1047-1059 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124713006372; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/038b13b134c84948ae45ebf210800b23

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