The implementation of genome sequencing in rare genetic diseases diagnosis: a pilot study from the Hong Kong genome project

Authors: Lam, Wai Kei Jacky ^{a, b, w}, Lau, Chak Sing ^{c, w}, Luk, Ho Ming ^{d, w}, Au, Lisa Wing Chi ^e, Chan, Gary C.P. ^e, Chan, Will Yap Hang ^{f, g}, Cheng, Shirley Sze Wing ^d, Cheng, Timothy Hua Tse ^h, Cheung, Li Li ^e, Cheung, Yiu Fai ^{i, j}, Chong, Josephine Shuk Ching ^k, Chu, Annie Tsz Wai ^l, Chung, Claudia Ching Yan ^l, Chung, Kin Lai ^m, Fung, Cheuk Wing ⁱ, Fung, Eva Lai Wah ^{k, n}, Gao, Yuan ^o, Ho, Stephanie ^d, Hue, Shirley Pik Ying ^l, Lee, Chi-Ho ^c, Lee, Tsz Leung ^p, Li, Philip Hei ^q, Lo, Hei Man ^l, Man Lo, Ivan Fai ^d, Loong, Herbert Ho Fung ^{r, s}, Ma, Becky Mingyao ^t, Ma, Wei ^l, Pang, Shirley Yin Yu ^o, Seto, Wai-Kay ^c, Siu, Steven Wai Kwan ^u, So, Ho ^e, Tam, Yuk Him ^v, Tang, Wenshu ^l, Wong, Rosanna Ming Sum ⁱ, Yap, Desmond Yat Hin ^t, Yau, Maggie Lo Yee ^{k, n}, Chung, Brian Hon Yin ^{j, l, ∗∗}, Lo, Su-Vui ^{l, ∗}

Source: In The Lancet Regional Health - Western Pacific February 2025 55

Comparative effectiveness and safety of BNT162b2 and CoronaVac in Hong Kong: A target trial emulation

Authors: Wan, Eric Yuk Fai, Wang, Boyuan, Lee, Amanda Lauren, Zhou, Jiayi, Chui, Celine Sze Ling, Lai, Francisco Tsz Tsun, Li, Xue, Wong, Carlos King Ho, Hung, Ivan Fan Ngai, Lau, Chak Sing, Chan, Esther Wai Yin, Wong, Ian Chi Kei

Source: In International Journal of Infectious Diseases September 2024 146

Association of sustained lupus low disease activity state with improved outcomes in systemic lupus erythematosus: a multinational prospective cohort study

Authors: Golder, Vera ^*, Kandane-Rathnayake, Rangi, Li, Ning, Louthrenoo, Worawit, Chen, Yi-Hsing, Cho, Jiacai, Lateef, Aisha, Hamijoyo, Laniyati, Luo, Shue Fen, Wu, Yeong-Jian, Navarra, Sandra V, Zamora, Leonid, Li, Zhanguo, Sockalingam, Sargunan, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Basnayake, Duminda, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Bae, Sang-Cheol, Goldblatt, Fiona, Oon, Shereen, O'Neill, Sean, Ng, Kristine, Law, Annie, Tugnet, Nicola, Kumar, Sunil, Tee, Cherica, Tee, Michael, Ohkubo, Naoaki, Tanaka, Yoshiya, Lau, Chak Sing, Hoi, Alberta, Nikpour, Mandana, Morand, Eric F

Source: In The Lancet Rheumatology August 2024 6(8):e528-e536

Multi-omics study reveals different pathogenesis of the generation of skin lesions in SLE and IDLE patients

Authors: Li, Qianwen, Jia, Chen, Pan, Wenjing, Liu, Hongmei, Tang, Congli, Weber, Daniel, Chen, Kaili, Long, Hai, Byrne-Steele, Miranda L., Han, Jian, He, Nongyue, Xiao, Rong, Zhao, Ming, Che, Nan, Guo, Qing, Gui, Guangji, Li, Shanshan, Si, Henan, Guo, Shuping, Liu, Hongye, Wang, Gang, Zhu, Guannan, Yang, Bin, Wang, Yu, Ding, Yan, Yang, Xianxu, Akihiko, Yoshimura, Lu, Liwei, Chang, Christopher, Chan, Vera, Lau, Chak-Sing, Qi, Hai, Liu, Wanli, Li, Song, Wu, Haijing, Lu, Qianjin

Source: In Journal of Autoimmunity June 2024 146

Recapitulating primary immunodeficiencies with expanded potential stem cells: Proof of concept with STAT1 gain of function

Authors: Liu, Xueyan, Chan, Vera S.F., Smith, Kenneth G.C., Ming, Chang, Or, Chung Sze, Tsui, Faria T.W., Gao, Bo, Cook, Matthew C., Liu, Pentao, Lau, Chak Sing, Li, Philip Hei

Source: In The Journal of Allergy and Clinical Immunology April 2024 153(4):1125-1139

Impact of low disease activity, remission, and complete remission on flares following tapering of corticosteroids and immunosuppressive therapy in patients with systemic lupus erythematous: a multinational cohort study

Authors: Cho, Jiacai ^*, Shen, Liang, Huq, Molla, Kandane-Rathnayake, Rangi, Golder, Vera, Louthrenoo, Worawit, Chen, Yi-Hsing, Hamijoyo, Laniyati, Luo, Shue-Fen, Wu, Yeong-Jian J, Zamora, Leonid, Li, Zhanguo, Sockalingam, Sargunan, Katsumata, Yasuhiro, Harigai, Masayoshi, Hao, Yanjie, Zhang, Zhuoli, Basnayake, Duminda, Chan, Madelynn, Kikuchi, Jun, Takeuchi, Tsutomu, Bae, Sang-Cheol, Oon, Shereen, O'Neill, Sean, Goldblatt, Fiona, Ng, Kristine Pek Ling, Law, Annie, Tugnet, Nicola, Kumar, Sunil, Tee, Cherica, Tee, Michael, Ohkubo, Naoaki, Tanaka, Yoshiya, Navarra, Sandra V, Lau, Chak Sing, Hoi, Alberta, Morand, Eric F, Nikpour, Mandana, Lateef, Aisha

Source: In The Lancet Rheumatology October 2023 5(10):e584-e593

Effectiveness of molnupiravir vs nirmatrelvir-ritonavir in non-hospitalised and hospitalised patients with COVID-19: a target trial emulation study

Authors: Wan, Eric Yuk Fai, Yan, Vincent Ka Chun, Wong, Zoey Cho Ting, Chui, Celine Sze Ling, Lai, Francisco Tsz Tsun, Li, Xue, Wong, Carlos King Ho, Hung, Ivan Fan Ngai, Lau, Chak Sing, Wong, Ian Chi Kei, Chan, Esther Wai Yin

Source: In eClinicalMedicine October 2023 64

Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination: a population-based cohort study

Authors: Peng, Kuan, Li, Xue, Yang, Deliang, Chan, Shirley C.W., Zhou, Jiayi, Wan, Eric Y.F., Chui, Celine S.L., Lai, Francisco T.T., Wong, Carlos K.H., Chan, Esther W.Y., Leung, Wai Keung, Lau, Chak-Sing, Wong, Ian C.K.

Source: In eClinicalMedicine September 2023 63

Long-term post-acute sequelae of COVID-19 infection: a retrospective, multi-database cohort study in Hong Kong and the UK

Authors: Lam, Ivan Chun Hang, Wong, Carlos King Ho, Zhang, Ran, Chui, Celine Sze Ling, Lai, Francisco Tsz Tsun, Li, Xue, Chan, Esther Wai Yin, Luo, Hao, Zhang, Qingpeng, Man, Kenneth Keng Cheung, Cheung, Bernard Man Yung, Tang, Sydney Chi Wai, Lau, Chak Sing, Wan, Eric Yuk Fai, Wong, Ian Chi Kei

Source: In eClinicalMedicine June 2023 60

Vaccine effectiveness of BNT162b2 and CoronaVac against SARS-CoV-2 omicron infection and related hospital admission among people with substance use disorder in Hong Kong: a matched case-control study

Authors: Huang, Caige ^*, Wei, Yue ^*, Yan, Vincent K C, Ye, Xuxiao, Kang, Wei, Yiu, Hei Hang Edmund, Shami, Jessica J P, Cowling, Benjamin J, Tse, Man Li, Castle, David J, Chui, Celine S L, Lai, Francisco T T, Li, Xue, Wan, Eric Y F, Wong, Carlos K H, Hayes, Joseph F, Chang, Wing Chung, Chung, Albert K K, Lau, Chak Sing, Wong, Ian C K, Chan, Esther W ^*

Source: In The Lancet Psychiatry June 2023 10(6):403-413

The indirect impact of the COVID-19 pandemic on people with type 2 diabetes mellitus and without COVID-19 infection: Systematic review and meta-analysis

Authors: Hu, Zhuoran, Youn, Hin Moi, Quan, Jianchao, Lee, Lily Luk Siu, Mak, Ivy Lynn, Yu, Esther Yee Tak, Chao, David Vai-Kiong, Ko, Welchie Wai Kit, Wong, Ian Chi Kei, Lau, Gary Kui Kai, Lau, Chak Sing, Lam, Cindy Lo Kuen, Wan, Eric Yuk Fai

Source: In Primary Care Diabetes June 2023 17(3):229-237

Ten-year outcomes of Perioperative Anaphylaxis Workup Study in Hong Kong (PAWS-HK): Performance of diagnostic modalities

Authors: Au, Elaine Y.L. ^*, Mak, Hugo W.F., Yeung, Maegan H.Y., Chiang, Valerie ^*, Lam, Ki ^*, Wong, Jane C.Y., Yeung, Heather H.F. ^*, Chan, Eric Y.T. ^*, Lau, Chak-sing, Li, Philip H.

Source: In Annals of Allergy, Asthma & Immunology June 2023 130(6):752-759

Comparative Effectiveness, Safety, and Real-World Outcomes of a Nurse-Led, Protocol-Driven Penicillin Allergy Evaluation From the Hong Kong Drug Allergy Delabelling Initiative (HK-DADI)

Authors: Kan, Andy K.C., Hui, Harris K.S., Li, Tin Sum, Chiang, Valerie, Wong, Jane C.Y., Chan, Tik Suet, Kwan, Ian Y.K., Shum, Wing Zi, Yeung, Matthew S.C., Au, Elaine Y.L., Ho, Carmen T.K., Lau, Chak Sing, Li, Philip H.

Source: In The Journal of Allergy and Clinical Immunology: In Practice February 2023 11(2):474-480

Prospective Study on the Efficacy and Impact of Cascade Screening and Evaluation of Hereditary Angioedema (CaSE-HAE)

Authors: Wong, Jane C.Y., Chiang, Valerie, Lam, Ki, Tung, Edmund, Au, Elaine Y.L., Lau, Chak Sing, Li, Philip H.

Source: In The Journal of Allergy and Clinical Immunology: In Practice November 2022 10(11):2896-2903

Monoclonal antibodies and Fc-fusion protein biologic medicines: A multinational cross-sectional investigation of accessibility and affordability in Asia Pacific regions between 2010 and 2020

Authors: Tong, Xinning, Li, Xue, Pratt, Nicole L., Hillen, Jodie B., Stanford, Tyman, Ward, Michael, Roughead, Elizabeth E., Lai, Edward Chia-Cheng, Shin, Ju-Young, Cheng, Franco W.T., Peng, Kuan, Lau, Chak Sing, Leung, Wai Keung, Wong, Ian C.K.

Source: In The Lancet Regional Health - Western Pacific September 2022 26

The Role of the Allergist in Coronavirus Disease 2019 Vaccine Allergy Safety: A Pilot Study on a “Hub-and-Spoke” Model for Population-Wide Allergy Service

Authors: Chiang, Valerie ^*, Saha, Chinmoy, Yim, Jackie, Au, Elaine Y.L. ^*, Kan, Andy K.C., Hui, Kong Siu Harris, Li, Tin Sum, Lo, Wing Lam Whitney, Hong, Yuh Dong, Ye, Jiaxi, Ng, Carmen, Ko, Welchie W.K., Ho, Carmen T.K., Lau, Chak Sing, Quan, Jianchao, Li, Philip H.

Source: In Annals of Allergy, Asthma & Immunology September 2022 129(3):308-312

Thromboembolic events and hemorrhagic stroke after mRNA (BNT162b2) and inactivated (CoronaVac) covid-19 vaccination: A self-controlled case series study

Authors: Chui, Celine Sze Ling, Fan, Min, Wan, Eric Yuk Fai, Leung, Miriam Tim Yin, Cheung, Edmund, Yan, Vincent Ka Chun, Gao, Le, Ghebremichael-Weldeselassie, Yonas, Man, Kenneth K.C., Lau, Kui Kai, Lam, Ivan Chun Hang, Lai, Francisco Tsz Tsun, Li, Xue, Wong, Carlos King Ho, Chan, Esther W., Cheung, Ching-Lung, Sing, Chor-Wing, Lee, Cheuk Kwong, Hung, Ivan Fan Ngai, Lau, Chak Sing, Chan, Joseph Yat Sun, Lee, Michael Kang-Yin, Mok, Vincent Chung Tong, Siu, Chung-Wah, Chan, Lot Sze Tao, Cheung, Terence, Chan, Frank Ling Fung, Leung, Anskar Yu-Hung, Cowling, Benjamin John, Leung, Gabriel Matthew, Wong, Ian Chi Kei

Source: In eClinicalMedicine August 2022 50

Introducing Incentives and Reducing Disincentives in Enhancing Deceased Organ Donation and Transplantation

Authors: Chow, Kai Ming, Ahn, Curie, Dittmer, Ian, Au, Derrick Kit-Sing, Cheung, Ian, Cheng, Yuk Lun, Lau, Chak Sing, Yeung, Deacons Tai-Kong, Li, Philip Kam-Tao

Source: In Seminars in Nephrology July 2022 42(4)

Autoimmune conditions following mRNA (BNT162b2) and inactivated (CoronaVac) COVID-19 vaccination: A descriptive cohort study among 1.1 million vaccinated people in Hong Kong

Authors: Li, Xue, Gao, Le, Tong, Xinning, Chan, Vivien K.Y., Chui, Celine S.L., Lai, Francisco T.T., Wong, Carlos K.H., Wan, Eric Y.F., Chan, Esther W.Y., Lau, Kui Kai, Lau, Chak Sing, Wong, Ian C.K.

Source: In Journal of Autoimmunity June 2022 130

Long-Term Results of Triple Immunosuppression With Tacrolimus Added to Mycophenolate and Corticosteroids in the Treatment of Lupus Nephritis

Authors: Yap, Desmond Y.H., Li, Philip Hei, Tang, Colin, So, Benjamin Y.F., Kwan, Lorraine P.Y., Chan, Gary C.W., Lau, Chak Sing, Chan, Tak Mao

Source: In Kidney International Reports March 2022 7(3):516-525