Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition.

Authors: Jiayi Wang, Nadine Brückner, Simon Weissmann, Thomas Günther, Shuyong Zhu, Carolin Vogt, Guorong Sun, Rongrong Guo, Renzo Bruno, Birgit Ritter, Lars Steinbrück, Benedikt B Kaufer, Daniel P Depledge, Adam Grundhoff, Abel Viejo-Borbolla

Source: PLoS Pathogens, Vol 21, Iss 2, p e1012367 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/4ae89ea9e09745b091d9d1082e88e551

Viral modulation of type II interferon increases T cell adhesion and virus spread

Authors: Carina Jacobsen, Nina Plückebaum, George Ssebyatika, Sarah Beyer, Lucas Mendes-Monteiro, Jiayi Wang, Kai A. Kropp, Víctor González-Motos, Lars Steinbrück, Birgit Ritter, Claudio Rodríguez-González, Heike Böning, Eirini Nikolouli, Paul R. Kinchington, Nico Lachmann, Daniel P. Depledge, Thomas Krey, Abel Viejo-Borbolla

Source: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0569487febc14ccf86b8f547b6011d69

In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice

Authors: Alice Rovai, BoMee Chung, Qingluan Hu, Sebastian Hook, Qinggong Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven R. Talbot, Lars Steinbrück, Jasper Götting, Jens Bohne, Simon A. Krooss, Michael Ott

Source: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/41baa3360d14427b871c13b614264a6d

Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch [version 2; peer review: 3 approved]

Authors: Áine O'Toole, Verity Hill, Oliver G. Pybus, Alexander Watts, Issac I. Bogoch, Kamran Khan, Jane P. Messina, The COVID-19 Genomics UK (COG-UK) consortium, Network for Genomic Surveillance in South Africa (NGS-SA), Brazil-UK CADDE Genomic Network, Houriiyah Tegally, Richard R. Lessells, Jennifer Giandhari, Sureshnee Pillay, Kefentse Arnold Tumedi, Gape Nyepetsi, Malebogo Kebabonye, Maitshwarelo Matsheka, Madisa Mine, Sima Tokajian, Hamad Hassan, Tamara Salloum, Georgi Merhi, Jad Koweyes, Jemma L. Geoghegan, Joep de Ligt, Xiaoyun Ren, Matthew Storey, Nikki E. Freed, Chitra Pattabiraman, Pramada Prasad, Anita S. Desai, Ravi Vasanthapuram, Thomas F. Schulz, Lars Steinbrück, Tanja Stadler, Swiss Viollier Sequencing Consortium, Antonio Parisi, Angelica Bianco, Darío García de Viedma, Sergio Buenestado-Serrano, Vítor Borges, Joana Isidro, Sílvia Duarte, João Paulo Gomes, Neta S. Zuckerman, Michal Mandelboim, Orna Mor, Torsten Seemann, Alicia Arnott, Jenny Draper, Mailie Gall, William Rawlinson, Ira Deveson, Sanmarié Schlebusch, Jamie McMahon, Lex Leong, Chuan Kok Lim, Maria Chironna, Daniela Loconsole, Antonin Bal, Laurence Josset, Edward Holmes, Kirsten St. George, Erica Lasek-Nesselquist, Reina S. Sikkema, Bas Oude Munnink, Marion Koopmans, Mia Brytting, V. Sudha rani, S. Pavani, Teemu Smura, Albert Heim, Satu Kurkela, Massab Umair, Muhammad Salman, Barbara Bartolini, Martina Rueca, Christian Drosten, Thorsten Wolff, Olin Silander, Dirk Eggink, Chantal Reusken, Harry Vennema, Aekyung Park, Christine Carrington, Nikita Sahadeo, Michael Carr, Gabo Gonzalez, SEARCH Alliance San Diego, National Virus Reference Laboratory, SeqCOVID-Spain, Danish Covid-19 Genome Consortium (DCGC), Communicable Diseases Genomic Network (CDGN), Dutch National SARS-CoV-2 surveillance program, Division of Emerging Infectious Diseases (KDCA), Tulio de Oliveira, Nuno Faria, Andrew Rambaut, Moritz U. G. Kraemer

Source: Wellcome Open Research, Vol 6 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://wellcomeopenresearch.org/articles/6-121/v2; https://doaj.org/toc/2398-502X

Access URL: https://doaj.org/article/63672d265a40472ea7302adbef66d81f

Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy

Authors: Berislav Bošnjak, Ivan Odak, Christiane Ritter, Klaus Stahl, Theresa Graalmann, Lars Steinbrück, Rainer Blasczyk, Christine S. Falk, Thomas F. Schulz, Hans Heinrich Wedemeyer, Markus Cornberg, Arnold Ganser, Reinhold Förster, Christian Koenecke

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: convalescent plasma (CP), COVID – 19, SARS – CoV – 2, NK cell, T cell, CD19 CAR-T cell, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.721738/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/6ca321676619473c9571183ea2adfb2b

Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 [version 1; peer review: 2 approved]

Authors: Áine O'Toole, Verity Hill, Oliver G. Pybus, Alexander Watts, Issac I. Bogoch, Kamran Khan, Jane P. Messina, The COVID-19 Genomics UK (COG-UK) consortium, Network for Genomic Surveillance in South Africa (NGS-SA), Brazil-UK CADDE Genomic Network, Houriiyah Tegally, Richard R. Lessells, Jennifer Giandhari, Sureshnee Pillay, Kefentse Arnold Tumedi, Gape Nyepetsi, Malebogo Kebabonye, Maitshwarelo Matsheka, Madisa Mine, Sima Tokajian, Hamad Hassan, Tamara Salloum, Georgi Merhi, Jad Koweyes, Jemma L. Geoghegan, Joep de Ligt, Xiaoyun Ren, Matthew Storey, Nikki E. Freed, Chitra Pattabiraman, Pramada Prasad, Anita S. Desai, Ravi Vasanthapuram, Thomas F. Schulz, Lars Steinbrück, Tanja Stadler, Swiss Viollier Sequencing Consortium, Antonio Parisi, Angelica Bianco, Darío García de Viedma, Sergio Buenestado-Serrano, Vítor Borges, Joana Isidro, Sílvia Duarte, João Paulo Gomes, Neta S. Zuckerman, Michal Mandelboim, Orna Mor, Torsten Seemann, Alicia Arnott, Jenny Draper, Mailie Gall, William Rawlinson, Ira Deveson, Sanmarié Schlebusch, Jamie McMahon, Lex Leong, Chuan Kok Lim, Maria Chironna, Daniela Loconsole, Antonin Bal, Laurence Josset, Edward Holmes, Kirsten St. George, Erica Lasek-Nesselquist, Reina S. Sikkema, Bas Oude Munnink, Marion Koopmans, Mia Brytting, V. Sudha rani, S. Pavani, Teemu Smura, Albert Heim, Satu Kurkela, Massab Umair, Muhammad Salman, Barbara Bartolini, Martina Rueca, Christian Drosten, Thorsten Wolff, Olin Silander, Dirk Eggink, Chantal Reusken, Harry Vennema, Aekyung Park, Christine Carrington, Nikita Sahadeo, Michael Carr, Gabo Gonzalez, SEARCH Alliance San Diego, National Virus Reference Laboratory, SeqCOVID-Spain, Danish Covid-19 Genome Consortium (DCGC), Communicable Diseases Genomic Network (CDGN), Dutch National SARS-CoV-2 surveillance program, Division of Emerging Infectious Diseases (KDCA), Tulio de Oliveira, Nuno Faria, Andrew Rambaut, Moritz U. G. Kraemer

Source: Wellcome Open Research, Vol 6 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://wellcomeopenresearch.org/articles/6-121/v1; https://doaj.org/toc/2398-502X

Access URL: https://doaj.org/article/4d50ca9e659b4b69b1e58f7d34df6deb

Human Cytomegalovirus Genome Diversity in Longitudinally Collected Breast Milk Samples

Authors: Jasper Götting, Katrin Lazar, Nicolás M. Suárez, Lars Steinbrück, Tabea Rabe, Rangmar Goelz, Thomas F. Schulz, Andrew J. Davison, Klaus Hamprecht, Tina Ganzenmueller

Source: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Subject Terms: cytomegalovirus, breast milk, genomes, strains, diversity, genotyping, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2021.664247/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/e9a135d933e847c884106a95ce93ff4e

Ex Vivo/In vivo Gene Editing in Hepatocytes Using 'All-in-One' CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template

Authors: Simon Alexander Krooss, Zhen Dai, Florian Schmidt, Alice Rovai, Julia Fakhiri, Akshay Dhingra, Qinggong Yuan, Taihua Yang, Asha Balakrishnan, Lars Steinbrück, Sangar Srivaratharajan, Michael Peter Manns, Axel Schambach, Dirk Grimm, Jens Bohne, Amar Deep Sharma, Hildegard Büning, Michael Ott

Source: iScience, Vol 23, Iss 1, Pp - (2020)

Subject Terms: Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004219305097; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/8489088995c34cbe8ba0b1a8c77f10b1

Analysis of Essential Viral Gene Functions after Highly Efficient Adenofection of Cells with Cloned Human Cytomegalovirus Genomes

Authors: Endrit Elbasani, Ildar Gabaev, Lars Steinbrück, Martin Messerle, Eva Maria Borst

Source: Viruses, Vol 6, Iss 1, Pp 354-370 (2014)

Subject Terms: human cytomegalovirus, bacterial artificial chromosomes, essential viral genes, transfection, adenovirus, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/6/1/354; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/d457466fa61a4e6c8bed7c1b1c1ae72f

PTree: pattern-based, stochastic search for maximum parsimony phylogenies

Authors: Ivan Gregor, Lars Steinbrück, Alice C. McHardy

Source: PeerJ, Vol 1, p e89 (2013)

Subject Terms: Phylogeny reconstruction, Maximum parsimony, Local search, Stochastic search, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/89.pdf; https://peerj.com/articles/89/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/59342967a1c642fdb1e31feaea44f324

Inference of genotype-phenotype relationships in the antigenic evolution of human influenza A (H3N2) viruses.

Authors: Lars Steinbrück, Alice Carolyn McHardy

Source: PLoS Computational Biology, Vol 8, Iss 4, p e1002492 (2012)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3330098?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/8142b476edd14d949184eac0abac331f

The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.

Authors: Ildar Gabaev, Lars Steinbrück, Claudia Pokoyski, Andreas Pich, Richard J Stanton, Reinhard Schwinzer, Thomas F Schulz, Roland Jacobs, Martin Messerle, Penelope C Kay-Fedorov

Source: PLoS Pathogens, Vol 7, Iss 12, p e1002432 (2011)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174689/pdf/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0cb876d627b3413fb328cb0e678021eb