Enhancing Prostate and Bladder Cancer Treatment: Exploring the Synergistic Potential of Entecavir and 5-Fluorouracil Combinations

Authors: Tânia Lourenço, Lara Marques, Eduarda Ribeiro, Nuno Vale

Source: BioMed, Vol 4, Iss 2, Pp 185-202 (2024)

Subject Terms: drug repurposing, prostate cancer, bladder cancer, entecavir, 5-fluorouracil, combination studies, Biotechnology, TP248.13-248.65, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2673-8430/4/2/15; https://doaj.org/toc/2673-8430

Access URL: https://doaj.org/article/d332d330a55f475e9b30f3225168cd55

Improving Individualized Salbutamol Treatment: A Population Pharmacokinetic Model for Oral Salbutamol in Virtual Patients

Authors: Lara Marques, Nuno Vale

Source: Pharmaceutics, Vol 17, Iss 1, p 39 (2024)

Subject Terms: salbutamol, popPK modeling, PBPK modeling, pharmacokinetics, covariates, interindividual variability, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/17/1/39; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/2aa9e737a766401fb9be652832486199

Cardiovascular Effects of a Glycosylated Flavonoids-Rich Leaf Extract from Brazilian Erythroxylum campestre: A Potential Health Bio-Input

Authors: Letícia Henrique Dantas Gomes de Lima, Marcos Willian Francelino Gomes, Thays Siqueira de Sá Curado, Lara Marques Naves, Stefanne Madalena Marques, Marilene Silva Oliveira, John Ihayi Ogbu, Antonio Carlos Severo Menezes, Giuliana Muniz Vila Verde, James Oluwagbamigbe Fajemiroye, Gustavo Rodrigues Pedrino

Source: Pharmaceuticals, Vol 17, Iss 11, p 1456 (2024)

Subject Terms: bioactivity, hypertension, medicinal plants, phytochemical, vascular resistance, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/11/1456; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/bfbdaa1f59614ac9b177a0e413486bfe

The Involvement of Hypoxia in the Response of Neuroblastoma Cells to the Exposure of Atorvastatin

Authors: Ana Salomé Correia, Lara Marques, Nuno Vale

Source: Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3333-3346 (2023)

Subject Terms: drug repurposing, atorvastatin, neuroblastoma cells, hypoxia-inducible factor-1, echinomycin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/45/4/218; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/bd6f3061cbda4348bd403d29f4d397fe

Unraveling the Impact of Salbutamol Polytherapy: Clinically Relevant Drug Interactions

Authors: Lara Marques, Nuno Vale

Source: Future Pharmacology, Vol 3, Iss 1, Pp 296-316 (2023)

Subject Terms: salbutamol, drug–drug interactions, pharmacokinetics, safety, adverse reactions, asthma, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2673-9879/3/1/19; https://doaj.org/toc/2673-9879

Access URL: https://doaj.org/article/5290cfb840f4436ea4a4379770f48c9a

Toward Personalized Salbutamol Therapy: Validating Virtual Patient-Derived Population Pharmacokinetic Model with Real-World Data

Authors: Lara Marques, Nuno Vale

Source: Pharmaceutics, Vol 16, Iss 7, p 881 (2024)

Subject Terms: interindividual variability, popPK modeling, PBPK modeling, salbutamol, pharmacokinetics, virtual data patients, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/7/881; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/3fb2dbd8fc60443ba2ee1d97779e69ba

Advancing Precision Medicine: A Review of Innovative In Silico Approaches for Drug Development, Clinical Pharmacology and Personalized Healthcare

Authors: Lara Marques, Bárbara Costa, Mariana Pereira, Abigail Silva, Joana Santos, Leonor Saldanha, Isabel Silva, Paulo Magalhães, Stephan Schmidt, Nuno Vale

Source: Pharmaceutics, Vol 16, Iss 3, p 332 (2024)

Subject Terms: precision medicine, in silico, clinical pharmacology, computational tools, patient-centered healthcare, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/3/332; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/b70cf52afdb74126b147e199402a5bd6

A peptide fraction from hardened common beans (Phaseolus vulgaris) induces endothelium-dependent antihypertensive and renal effects in rats

Authors: Juliana Vila Verde Ribeiro, Daniel Graziani, Jhulle Horrane Moreira Carvalho, Michelle Mendanha Mendonça, Lara Marques Naves, Helton Freires Oliveira, Hericles Mesquita Campos, Maria Clorinda Soares Fioravanti, Lilian Fernanda Pacheco, Patricia Maria Ferreira, Gustavo Rodrigues Pedrino, Paulo César Ghedini, Kátia Flávia Fernandes, Karla de Aleluia Batista, Carlos Henrique Xavier

Source: Current Research in Food Science, Vol 6, Iss , Pp 100410- (2023)

Subject Terms: Hypertension, Renal function, Hydroelectrolytic balance, Bioactive peptides, Hard-to-cook, Common beans, Nutrition. Foods and food supply, TX341-641, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665927122002325; https://doaj.org/toc/2665-9271

Access URL: https://doaj.org/article/ad4c1686431f489aaed342e46fcb3c1a

Exploring the Role of Drug Repurposing in Bridging the Hypoxia–Depression Connection

Authors: Ana Salomé Correia, Lara Marques, Armando Cardoso, Nuno Vale

Source: Membranes, Vol 13, Iss 9, p 800 (2023)

Subject Terms: drug repurposing, hypoxia-inducible factor-1, serotonin receptors, cobalt chloride, Echinomycin, Chemical technology, TP1-1185, Chemical engineering, TP155-156

File Description: electronic resource

Relation: https://www.mdpi.com/2077-0375/13/9/800; https://doaj.org/toc/2077-0375

Access URL: https://doaj.org/article/4fa4be9fae8242ac8edc787b473b7a62

Prediction of CYP-Mediated Drug Interaction Using Physiologically Based Pharmacokinetic Modeling: A Case Study of Salbutamol and Fluvoxamine

Authors: Lara Marques, Nuno Vale

Source: Pharmaceutics, Vol 15, Iss 6, p 1586 (2023)

Subject Terms: drug–drug interaction, salbutamol, fluvoxamine, PBPK modeling, pharmacokinetics, simulation, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/6/1586; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/3f16d83aedea476d9b1fa10387b926bf

The Effects of Chitosan on the Healing Process of Oral Mucosa: An Observational Cohort Feasibility Split-Mouth Study

Authors: Gonçalo de Jesus, Lara Marques, Nuno Vale, Rui Amaral Mendes

Source: Nanomaterials, Vol 13, Iss 4, p 706 (2023)

Subject Terms: chitosan, wound healing, oral mucosa, oral surgery, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/13/4/706; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/3277855459684001bdf1f7aa7432a385

Therapeutic Options for Chlamydia trachomatis Infection: Present and Future

Authors: Rafaela Rodrigues, Lara Marques, Pedro Vieira-Baptista, Carlos Sousa, Nuno Vale

Source: Antibiotics, Vol 11, Iss 11, p 1634 (2022)

Subject Terms: Chlamydia trachomatis, genital infection, treatment guidelines, drug resistance, screening, antibiotics, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/11/1634; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/6dd032d4a34443e7b08a76e617dafa8a

Impact of alcohol gel on hand bacteria in healthcare professionals

Authors: Gabriel Faria, Ralciane Menezes, Priscila Alves, Lara Marques, Nagela Silva, Meliza Bessa, Felipe Silva, Denise Röder, Reginaldo Pedroso, Mario Penatti

Source: Revista de Epidemiologia e Controle de Infecção, Vol 11, Iss 3 (2021)

Subject Terms: hand hygiene, health personnel, neonatal intensive care units, microbial drug resistance., Medicine, Internal medicine, RC31-1245, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://online.unisc.br/seer/index.php/epidemiologia/article/view/16493; https://doaj.org/toc/2238-3360

Access URL: https://doaj.org/article/43512c0aeb614589aa74326db7b89350

Medullary Noradrenergic Neurons Mediate Hemodynamic Responses to Osmotic and Volume Challenges

Authors: Stefanne Madalena Marques, Lara Marques Naves, Talita de Melo e Silva, Keilah Valéria Naves Cavalcante, Juliana Milan Alves, Marcos Luiz Ferreira-Neto, Carlos Henrique de Castro, Andre Henrique Freiria-Oliveira, James Oluwagbamigbe Fajemiroye, Rodrigo Mello Gomes, Eduardo Colombari, Carlos Henrique Xavier, Gustavo Rodrigues Pedrino

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: central nervous system, resuscitation, lesion, blood pressure, hypertonic saline, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.649535/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/bdbe41bf6e9143bd8d085db875a3b3a6

New Data for Nebivolol after In Silico PK Study: Focus on Young Patients and Dosage Regimen

Authors: Lara Marques, Bárbara Costa, Nuno Vale

Source: Pharmaceutics, Vol 14, Iss 9, p 1911 (2022)

Subject Terms: Nebivolol, in silico pharmacology, population PK, dosage regimen, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/9/1911; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/161ef9fccbbf4ea398b320807bc4a0e4

Análise estatística da qualidade das medidas das propriedades de forma de agregados com o uso do Processamento Digital de Imagens (PDI)

Authors: Daniele Soares Ibiapina, Lara Marques Diogenes, Veronica Teixeira Franco Castelo Branco, Silvia Maria de Freitas, Laura Maria Goretti da Motta, Daianne Fernandes Diogenes

Source: Transportes, Vol 28, Iss 5 (2020)

Subject Terms: Análise estatística. Propriedades de forma de agregados. Processamento Digital de Imagem (PDI)., Transportation engineering, TA1001-1280

File Description: electronic resource

Relation: https://www.revistatransportes.org.br/anpet/article/view/1865; https://doaj.org/toc/2237-1346

Access URL: https://doaj.org/article/220c1e0229fa45baa37a2e23e4081117

Increased global transcription activity as a mechanism of replication stress in cancer

Authors: Panagiotis Kotsantis, Lara Marques Silva, Sarah Irmscher, Rebecca M. Jones, Lisa Folkes, Natalia Gromak, Eva Petermann

Source: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/11549dd2c7d8445a96d11f1f28cfaa77

Proposição de um sistema de classificação das propriedades de forma de agregados caracterizados com o uso do processamento digital de imagens a partir de materiais oriundos do Brasil

Authors: Daniele Soares Ibiapina, Verônica Teixeira Franco Castelo Branco, Lara Marques Diogenes, Laura Maria Goretti da Motta, Silvia Maria de Freitas

Source: Transportes, Vol 26, Iss 4 (2018)

Subject Terms: Propriedades de forma de agrega-dos, Processamento digital de imagem (PDI), Análises estatísticas., Transportation engineering, TA1001-1280

File Description: electronic resource

Relation: https://revistatransportes.org.br/anpet/article/view/1510; https://doaj.org/toc/2237-1346

Access URL: https://doaj.org/article/c69f8b963dda43cc8ebed6e19ce81078

Role of the Carotid Bodies in the Hypertensive and Natriuretic Responses to NaCl Load in Conscious Rats

Authors: Elaine Fernanda da Silva, Aryanne Batista Soares de Melo, Eulício de Oliveira Lobo Júnior, Karla Lima Rodrigues, Lara Marques Naves, Wendell Karlos Tomazelli Coltro, Ana Cristina Silva Rebelo, André Henrique Freiria-Oliveira, José Vanderlei Menani, Gustavo Rodrigues Pedrino, Eduardo Colombari

Source: Frontiers in Physiology, Vol 9 (2018)

Subject Terms: carotid afferents, blood pressure, sodium balance, hypernatremia, high salt intake, fluid-electrolyte control, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2018.01690/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/36dcdd383b414479a96904a559697419

Hypertonic saline solution evokes cardiovascular recovery in hemorrhagic rats dependent on GABA A and β-adrenergic transmission in the subfornical organ

Authors: da Silva, Amanda Barbosa Coelho ^a, Marques, Stefanne Madalena ^a, Fajemiroye, James O. ^b, Colombari, Eduardo ^c, Xavier, Carlos Henrique ^b, Ferreira-Neto, Marcos Luiz ^d, Naves, Lara Marques ^{a, 1}, Pedrino, Gustavo Rodrigues ^{a, ⁎, 1}

Source: In Autonomic Neuroscience: Basic and Clinical April 2025 258