A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma.

Authors: Rendo, Veronica, Lee, Eudocia Q., Bossi, Connor, Khuu, Nicholas, Rudek, Michelle A., Pal, Sangita, Azazmeh, Narmen, Rashid, Rumana, Lin, Jia-Ren, Cusick, Margaret, Reynolds, Abigail R. N., Fassinou, Auriole C. R., Ayoub, Georges, Malinowski, Seth, Lapinskas, Emily, Pisano, William, Jeang, John, Stopka, Sylwia A., Regan, Michael S., Spetz, Johan

Source: Science Translational Medicine; 2/19/2025, Vol. 17 Issue 786, p1-18, 18p

Subject Terms: BONE marrow cells, PROGRESSION-free survival, OVERALL survival, CELL death, DNA sequencing

CaMKII binds both substrates and activators at the active site

Authors: Özden, Can, Sloutsky, Roman, Mitsugi, Tomohiro, Santos, Nicholas, Agnello, Emily, Gaubitz, Christl, Foster, Joshua, Lapinskas, Emily, Esposito, Edward A., Saneyoshi, Takeo, Kelch, Brian A., Garman, Scott C., Hayashi, Yasunori, Stratton, Margaret M.

Source: In Cell Reports 12 July 2022 40(2)

Characterization of CaMKIIα holoenzyme stability

Authors: Torres‐Ocampo, Ana P., Özden, Can, Hommer, Alexandra, Gardella, Anne, Lapinskas, Emily, Samkutty, Alfred, Esposito, Edward, Garman, Scott C, Stratton, Margaret M

Source: Protein science. 29(6):1524-1534

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107629392.0x000001&indx=1&recIds=ETOCvdc_100107629392.0x000001

Glioma genetic profiles associated with electrophysiologic hyperexcitability.

Authors: Tobochnik, Steven, Dorotan, Maria Kristina C, Ghosh, Hia S, Lapinskas, Emily, Vogelzang, Jayne, Reardon, David A, Ligon, Keith L, Bi, Wenya Linda, Smirnakis, Stelios M, Lee, Jong Woo

Source: Neuro-Oncology; Feb2024, Vol. 26 Issue 2, p323-334, 12p

Effect of PIK3CA variants on glioma-related epilepsy and response to treatment

Authors: Tobochnik, Steven ^*, Pisano, William, Lapinskas, Emily, Ligon, Keith L., Lee, Jong Woo

Source: In Epilepsy Research September 2021 175

4. Glioblastomas with MAPK pathway alterations show low grade histologic features and present novel therapeutic targets

Authors: Meredith, David, Gupta, Sneha, Grieco, Kristina, Pisano, William, Lapinskas, Emily, Dubuc, Adrian

Source: Cancer genetics. 260(S1):2-2

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157976310.0x000001&indx=1&recIds=ETOCvdc_100157976310.0x000001

Characterization of Camkiialpha Holoenzyme Stability

Authors: Torres-Ocampo, Ana P., Özden, Can, Hommer, Alexandra, Gardella, Anne, Lapinskas, Emily, Samkutty, Alfred, Esposito, Edward, Garman, Scott C., Stratton, Margaret

Source: Biophysical journal. 120(S1):199a-199a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135824269.0x000001&indx=1&recIds=ETOCvdc_100135824269.0x000001

Early EEG hyperexcitability is associated with decreased survival in newly diagnosed IDH-wildtype glioma.

Authors: Tobochnik, Steven, Lapinskas, Emily, Vogelzang, Jayne, Ligon, Keith L., Lee, Jong Woo

Source: Journal of Neuro-Oncology; Aug2022, Vol. 159 Issue 1, p211-218, 8p

Interim Analysis of Mmrf Curecloud Research Initiative Identifies High Prevalence and Patterns of Clonal Hematopoiesis of Indeterminate Potential (CHIP) Mutations in a Real World Myeloma Cohort

Authors: Jayasinghe, Reyka G, Kim, Annette S., Dowdell, Teni, Cibulskis, Carrie, Yesil, Jennifer, Chatterjee, Debanjana, Likens, Michele, Mehr, Shaadi, Saravanamuthu, Cartik, Alberge, Jean-Baptiste, Lapinskas, Emily, Labkoff, Steven E, Ligon, Keith L, Cho, Hearn Jay, Ghobrial, Irene M., Auclair, Daniel

Source: In Blood 23 November 2021 138 Supplement 1:2197-2197

Correction to: Early EEG hyperexcitability is associated with decreased survival in newly diagnosed IDH-wildtype glioma.

Authors: Tobochnik, Steven, Lapinskas, Emily, Vogelzang, Jayne, Ligon, Keith L., Lee, Jong Woo

Source: Journal of Neuro-Oncology; Aug2022, Vol. 159 Issue 1, p219-219, 1p