Effect of colchicine on perioperative atrial fibrillation and myocardial injury after non-cardiac surgery in patients undergoing major thoracic surgery (COP-AF): an international randomised trial

Authors: Conen, David, Devereaux, PJ, Vincent, Jessica, Wang, Michael Ke, Wells, Jennifer R., Healey, Jeff S., Landoni, Giovanni, McIntyre, William F., Popova, Ekaterine, Sessler, Daniel I., Srinathan, Sadeesh K., Amir, Mohammed, Bangdiwala, Shrikant I., Bossard, Matthias, Chan, Matthew TV, Eikelboom, John W., Fleischmann, Edith, Jolly, Sanjit, Montes, Felix Ramón, Reimer, Cara, Schmartz, Denis, Wang, Chew Yin, Ofori, Sandra N., Blum, Steffen, Alvarez-Garcia, Jesus, Lo Bianco, Giuliana, Traquair, Hugh, Guerrero-Pinedo, Fernando Andres, Oleynick, Christopher, Meyre, Pascal B., Méndez-Zurita, Francisco, Chiarella-Redfern, Helene, Marcucci, Maura, Donati, Francesco, Gonzalez-Osuna, Aranzazu, Minervini, Fabrizio, Moreno Weidmann, Zoraida, Guerra-Ramos, Jose M., Dion, Gabriel, Ramos-Pachón, Anna, Borges, Flavia K., de Sa Boasquevisque, Danielle, Mosconi, Maria Giulia, Amarenco, Pierre, Mitchell, L. Brent, Wyse, George, Cheng, Davy, McAlister, Finlay A., Wells, George A., Baskaran, Geethan, Burns, Andrew T., Gennaccaro, Julia, Howe, Rosemary, Mastrangelo, Louise, Pettit, Shirley, Popovic, Michelle, Shahbaz, Subana, Tosh, Makayla, Zucchetto, Simona J., Heenan, Laura, Lee, Shun Fu, Li, Zhuoru, Xu, Lizhen, Kabon, Barbara, Hoetzenecker, Konrad, Schweiger, Thomas, Reiterer, Christian, Zotti, Oliver, Bsuchner, Paul, Hochreiter, Beatrix, Taschner, Alexander, Adamowitsch, Nikolas, Horvath, Katharina, Hantáková, Nicole, Bidgoli, Javad, Huybrechts, Isabelle, Cappeliez, Serge, Neary, John D., Shargall, Yaron, Tandon, Vikas, Finley, Christian, Agzarian, John, Hanna, Waël, Abdulrahman, Muammar, Lawrence, Kelly, Gregus, Krysten, Quraishi, Faraaz, Wikkerink, Spencer, Wallace, Christine, Prine, Merissa, Gregus, Emily, Hare, Jacqueline, Lombardo, Kristen, Fezia, Behashta, Columbus, Teresa, Rushton, Jacob, DuMerton, Deborah, Reid, Ken, Parlow, Joel, Chung, Wiley, Karizhenskaia, Maria, Malik, Aftab, Tanzola, Rob, Giles, Andrew, McLean, Sean R., McGuire, Anna, Lohser, Jens, Lim, Shirley, Grey, Rebecca, Yee, John, Grant, Kyle, Lee, Alex L., Choi, James J., Dewar, Leith R., Durkin, Christopher, Schisler, Travis, Hecht, Patrick, Hughes, Bevan, Kidane, Biniam, Liu, Richard, Tan, Lawrence, Gowing, Stephen, Buduhan, Gordon, Enns, Stephanie, Poole, Emma, Graham, Kristin, Dubik, Niina, Chin, Alex, Maziak, Donna E., Seely, Andrew JE, Gilbert, Sebastien, Villeneuve, P. James, Sundaresan, Sudhir, Gingrich, Molly, Fazekas, Anna, Bucciero, Kirby, Malthaner, Richard A., Lewis, Deb, Fortin, Dalilah, Qiabi, Mehdi, Nayak, Rahul, Plourde, Madelaine Marie, Haider, Tehmina, Murphy, Rowan, Sellers, Daniel, Donahoe, Laura, Lefebvre, Marco, Lanthier, Luc, Ko, Michael Augustine, Parente, David, Cheung, Victoria, Schieman, Colin, Bessissow, Amal, Wong, Randolph HL, Joynt, Gavin M., Lam, Carmen KM, Lau, Rainbow WH, Wan, Innes YP, Underwood, Malcolm J., Wu, William KK, Wong, Wai Tat, Choi, Gordon YS, Lee, Eva, Hui, Ka Yan, Fung, Beaker, Chan, Chee Sam, Ng, Fung Kei, Thung, Kin Hoi, Gutiérrez-Soriano, Laura, Castañeda, Laura Carmenza, Téllez, Luis Jaime, Ortiz-Ramirez, Lina Marcela, Baiardo-Redaelli, Martina, Belletti, Alessandro, Dieci, Elisa, Monaco, Fabrizio, Muriana, Piergiorgio, Nakhnoukh, Cristina, Novellis, Pierluigi, Turi, Stefano, Viscardi, Stefano, Veronesi, Giulia, Voltolini, Luca, Bongiolatti, Stefano, Salvicchi, Alberto, Gatteschi, Lavinia, Indino, Rossella, Tombelli, Simone, Ravasin, Alice, Salimbene, Ottavia, Rosboch, Giulio Luca, Balzani, Eleonora, Ceraolo, Edoardo, Neitzert, Luca, Brazzi, Luca, Londero, Francesco, Grossi, William, Massullo, Domenico, Fiorelli, Silvia, Margaritora, Stefano, Hashim, Shahrul Amry, Krishnasamy, Sivakumar, See, Woan Shiang, Nawaz, Mohammed Asghar, Bilal, Haris, Trujillo Reyes, Juan Carlos, Martínez-Téllez, Elisabeth, Belda Sanchis, Josep, Planas Canovas, Georgina, Libreros Niño, Alejandra, Parera Ruiz, Ana, Cladellas Gutierrez, Esther, Guarino, Mauro, Urrutia Cuchi, Gerard, Argilaga Nogues, Marta, Rovira Juan, Anna, Medina-Aedo, Melixa, Turró Castillejo, Mª Asunción, Gil Sanchez, Josep Mª, Araúz-Sarmiento, Ibell, Herranz Perez, Gracia, Chavarria Murillo, Stephania, Garcia-Osuna, Alvaro, Rodriguez-Arias, Ainhoa, Berga Garrote, Nuria, Martín Grande, Ascension, Parise Roux, Diego, Gajate Martín, Luis, De Pablo Pajares, Angélica, Candela Toha, Angel Manuel, Moreno Mata, Nicolás, Muñoz Molina, Gema, Caballero Silva, Usue, Cabañero, Alberto, Fra Fernandez, Sara, Cavestany García-Matres, Cristina, Simón, Luisa, Montenegro, Cristina, Pozo, Sergio, Gonzàlez-Tallada, Anna, González Suarez, Susana, Ribas Ball, Montserrat, De Nadal Clanchet, Miriam, Pérez Vélez, Javier, Cruz, Patrícia, Sánchez-Pedrosa, Guillermo, Duque, Patricia, González, Guillermo, Huerta, Luis, Rodríguez, Laura, Garutti, Ignacio, Ruiz-Villa, Laura, Martí-Ejarque, Maria del Mar, Gili-Bueno, Mireia, Maddio Vieyra, Ricardo Matias, Fibla, Juan J., Durán, Núria, de Temple Pla, Marina, Rodríguez-Fuster, Alberto, Bermejo-Martínez, Silvia, Carramiñana, Albert, Opitz, Isabelle, Etienne, Harry, Cata, Juan P., Guerra-Londono, Juan Jose, Rajaram, Ravi, Corrales, German, Vaporciyan, Ara, Mehran, Reza, Sepesi, Boris, Walsh, Garrett, Rice, David, Cukierman, Daniel S., Swisher, Stephen, Marchant, Bryan E., Harris, Lynne C., Cusson, Bruce D., Miller, Scott A., Ayad, Sabry, Araujo, Jorge, Marquez-Roa, Leonardo, Hofstra, Richard L., Wudel, Jr., Leonard J., Minear, Steven C., Teixeira, Camila, Pimentel, Mario, Popoff, Andrew M., Marsack, Kelly, Meehan, Sarah, Chen, Tzonghuei H., Essandoh, Michael, Poppers, Jeremy S., Ke Wang, Michael, Chan, Matthew T V, Cata, Juan P, McLean, Sean R, Srinathan, Sadeesh K, Reyes, Juan Carlos Trujillo, Grande, Ascension Martín, Tallada, Anna Gonzalez, Sessler, Daniel I, Maziak, Donna E, McIntyre, William F, Wong, Randolph H L, McGuire, Anna L, Roux, Diego Parise, Wells, Jennifer R, Ofori, Sandra N, Eikelboom, John W, Jolly, Sanjit S, Healey, Jeff S, Devereaux, P J

Source: In The Lancet 4-10 November 2023 402(10413):1627-1635

Rationale and design of the colchicine for the prevention of perioperative atrial fibrillation in patients undergoing major noncardiac thoracic surgery (COP-AF) trial

Authors: Devereaux, Vincent, Jessica, Wang, Michael Ke, Wells, Jennifer R., Conen, David, Devereaux, PJ, Healey, Jeff S., Landoni, Giovanni, McIntyre, William F., Popova, Ekaterine, Sessler, Daniel I., Srinathan, Sadeesh K., Amir, Mohammed, Bangdiwala, Shrikant I., Bossard, Matthias, Chan, Matthew T.V., Eikelboom, John W., Fleischmann, Edith, Jolly, Sanjit S., Montes, Felix Ramón, Reimer, Cara, Schmartz, Denis, Wang, Chew Yin, Alvarez-Garcia, Jesus, Bianco, Giuliana Lo, Blum, Steffen, Boasquevisque, Danielle de Sa, Borges, Flavia K., Chiarella-Redfern, Helene, Gonzalez-Osuna, Aranzazu, Guerra-Ramos, Jose M., Marcucci, Maura, Meyre, Pascal B., Ofori, Sandra N., Oleynick, Christopher, Ramos-Pachón, Anna, Traquair, Hugh, Mitchell, L. Brent, Wyse, George, Cheng, Davy, McAlister, Finlay A., Wells, George A., Baskaran, Geethan, Gennaccaro, Julia, Howe, Rosemary, Mastrangelo, Louise, Pettit, Shirley, Shahbaz, Subana, Tosh, Makayla, Zucchetto, Simona J., Heenan, Laura, Lee, Shun Fu, Li, Zhuoru, Xu, Lizhen, Kabon, Barbara, Reiterer, Christian, Taschner, Alexander, Horvath, Katharina, Adamowitsch, Nikolas, Zotti, Oliver, Hantáková, Nicole, Hochreiter, Beatrix, Huybrechts, Isabelle, Cappeliez, Serge, Neary, John D., Shargall, Yaron, Tandon, Vikas, Finley, Christian, Agzarian, John, Hanna, Waël, Abdulrahman, Muammar, Lawrence, Kelly, Gregus, Krysten, Quraishi, Faraaz, Wikkerink, Spencer, Wallace, Christine, Prine, Merissa, Gregus, Emily, Hare, Jacqueline, Lombardo, Kristen, Fezia, Behashta, Columbus, Teresa, DuMerton, Deborah, Reid, Ken, Parlow, Joel, Chung, Wiley, Karizhenskaia, Maria, Malik, Aftab, Kidane, Biniam, Liu, Richard, Tan, Lawrence, Gowing, Stephen, Buduhan, Gordon, Enns, Stephanie, Poole, Emma, Graham, Kristin, McLean, Sean R., McGuire, Anna, Lohser, Jens, Lim, Shirley, Grey, Rebecca, Grant, Kyle, Lee, Alex L., Choi, James J., Dewar, Leith R., Yee, John, Maziak, Donna E., Seely, Andrew J.E., Gilbert, Sebastien, Villeneuve, P. James, Sundaresan, Sudhir, Moffatt-Bruce, Susan D., Gingrich, Molly, Fazekas, Anna, Bucciero, Kirby, Malthaner, Richard A., Lewis, Deb, Fortin, Dalilah, Qiabi, Mehdi, Nayak, Rahul, Plourde, Madelaine Marie, Sellers, Daniel, Donahoe, Laura, Lefebvre, Marco, Lanthier, Luc, Schieman, Colin, Bessissow, Amal, Joynt, Gavin M., Wong, Randolph H.L., Lau, Rainbow W.H., Wong, Wai Tat, Choi, Gordon Y.S., Lee, Eva, Hui, Ka Yan, Fung, Beaker, Chan, Chee Sam, Gutiérrez-Soriano, Laura, Castañeda, Laura Carmenza, Téllez, Luis Jaime, Ortiz-Ramirez, Lina Marcela, De Santis, Simona, Favaro, Giovanni, Muriana, Piergiorgio, Nakhnoukh, Cristina, Novellis, Pierluigi, Turi, Stefano, Veronesi, Giulia, Angelini, Matteo, Voltolini, Luca, Bongiolatti, Stefano, Salvicchi, Alberto, Gatteschi, Lavinia, Indino, Rossella, Tombelli, Simone, Ravasin, Alice, Salimbene, Ottavia, Rosboch, Giulio Luca, Balzani, Eleonora, Massullo, Domenico, Fiorelli, Silvia, Londero, Francesco, Grossi, William, Ng, Tyng Yan, See, Woan Shiang, Nawaz, Mohammed Asghar, Reyes, Juan Carlos Trujillo, Tellez, Elisabeth Martinez, Sanchis, Josep Belda, Cánovas, Georgina Planas, Ruiz, Ana Parera, Gutierrez, Esther Cladellas, Guarino, Mauro, Cuchi, Gerard Urrutia, Nogues, Marta Argilaga, Juan, Anna Rovira, Medina-Aedo, Melixa, Grande, Ascensión Martín, Roux, Diego Parise, Martín, Luis Gajate, Pajares, Angélica De Pablo, Toha, Angel Manuel Candela, Mata, Nicolás Moreno, Molina, Gema Muñoz, Silva, Usue Caballero, Cabañero, Alberto, Fernandez, Sara Fra, Tallada, Anna Gonzàlez, Suarez, Susana González, Ball, Montserrat Ribas, Clanchet, Miriam De Nadal, Ruiz-Villa, Laura, Martí-Ejarque, M.M., Gili-Bueno, Mireia, Ferrández, Jorge Hernández, Llobet, Neus Pons, Cruz, Patricia, Sánchez-Pedrosa, Guillermo, Duque, Patricia, Azcárate, Leire, Martín-Albo, Lorena, Rodríguez-Fuster, Alberto, Bermejo-Martínez, Silvia, Carramiñana, Albert, Minervini, Fabrizio, Cata, Juan P., Rajaram, Ravi, Corrales, German, Guerra-Londono, Juan Jose, Mehran, Reza, Sepesi, Boris, Walsh, Garrett, Cukierman, Daniel S., Marchant, Bryan E., Harris, Lynne C., Cusson, Bruce D., Miller, Scott A., Minear, Steven C., Teixeira, Camila, Pimentel, Mario, Popoff, Andrew M., Cheung, Wing Lee, Marsack, Kelly, Ayad, Sabry, Araujo, Jorge, Chen, Tzonghuei H., Essandoh, Michael, Poppers, Jeremy S., Trujillo Reyes, Juan Carlos, Gonzalez Tallada, Anna, Garg, Amit X.

Source: In American Heart Journal May 2023 259:87-96

Influence of Blood Pressure and Other Clinical Variables on Long-Term Mortality in a Cohort of Elderly Subjects with Type 2 Diabetes

Authors: Tessier, Daniel M. ^*, Meneilly, Graydon S., Moleski, Luc, Trottier, Lise, Lanthier, Luc

Source: In Canadian Journal of Diabetes February 2016 40(1):12-16

Chez les sujets hospitalisés avec bactériémie, un traitement antibiotique de 7 jours est-il non inférieur à un traitement de 14 jours en termes d’impact sur la mortalité ?

Alternate Title: In hospitalized patients with bacteremia, is a 7-day antibiotic treatment noninferior to a 14-day treatment with respect to mortality? (English)

Authors: Lanthier, Luc ^{a, ⁎}, Carignan, Alex ^b, Mutchmore, Alexandre ^a, Plourde, Marc-Émile ^c, Cauchon, Michel ^d

Source: In La revue de médecine interne March 2025 46(3):183-184

Chez les personnes avec obésité et apnée du sommeil obstructive modérée à sévère, est-ce que le tirzépatide est efficace pour diminuer l’indice d’apnée-hypopnée comparativement au placebo tout en étant sécuritaire ?

Alternate Title: In patients with obesity and moderate to severe obstructive sleep apnea, is tirzepatide effective in reducing the apnea-hypopnea index compared to placebo, and is it safe? (English)

Authors: Mutchmore, Alexandre ^a, Cauchon, Michel ^b, Plourde, Marc-Émile ^c, Lanthier, Luc ^{a, ⁎}

Source: In La revue de médecine interne February 2025 46(2):124-125

Chez les sujets avec insuffisance cardiaque à fraction d’éjection préservée ou légèrement réduite, la finérénone est-elle efficace pour diminuer un composite d’exacerbation d’insuffisance cardiaque et de décès d’origine cardiovasculaire tout en étant sécuritaire, comparativement au placebo ?

Alternate Title: In patients with heart failure with preserved or mildly reduced ejection fraction, is finerenone effective in reducing a composite of heart failure exacerbation and cardiovascular death compared to placebo, and is it safe? (English)

Authors: Lanthier, Luc ^{a, ⁎}, Mutchmore, Alexandre ^a, Plourde, Marc-Émile ^b, Cauchon, Michel ^c

Source: In La revue de médecine interne January 2025 46(1):57-58

Chez les femmes enceintes avec HTA préexistante légère, est-ce qu'une stratégie de traitement utilisant une cible de traitement<140/90mmHg comparativement à une surveillance sans traitement sauf si la TA>160/105mmHg réduit l'incidence de complications maternelles et périnatales tout en étant sécuritaire?

Authors: Lanthier, Luc, Sauvé, Nadine, Plourde, Marc-Émile, Cauchon, Michel

Source: Revue de médecine interne. 43(8):514-515

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169708876.0x000001&indx=1&recIds=ETOCvdc_100169708876.0x000001

An Interprofessional Qualitative Study of Barriers and Potential Solutions for the Safe Use of Insulin in the Hospital Setting

Authors: Rousseau, Marie-Pierre, Beauchesne, Marie-France, Naud, Alex-Sandra, Leblond, Julie, Cossette, Benoît, Lanthier, Luc, Grondin, Frédéric, Bernier, Frédéric

Source: In Canadian Journal of Diabetes April 2014 38(2):85-89

Chez les adultes admis aux soins intensifs et sous ventilation mécanique, l’utilisation du pantoprazole en prophylaxie diminue-t-elle le risque d’hémorragie digestive haute tout en étant sécuritaire ?

Alternate Title: In mechanically ventilated adult patients admitted to intensive care, does the use of pantoprazole for prophylaxis reduce the risk of gastrointestinal bleeding compared to placebo, and is it safe? (English)

Authors: Lanthier, Luc, Mayette, Michaël, Mutchmore, Alexandre, Plourde, Marc-Émile, Cauchon, Michel

Source: In La revue de médecine interne December 2024 45(12):787-788

Chez les sujets avec diabète de type 2 et insuffisance rénale chronique, est-ce que le sémaglutide prévient l’insuffisance rénale terminale, la perte significative de fonction rénale ou le décès de causes rénales ou cardiovasculaires comparativement au placebo, tout en étant sécuritaire ?

Alternate Title: Among patients with type 2 diabetes and chronic kidney disease, does semaglutide prevent end-stage renal disease, significant loss of kidney function, or death from renal or cardiovascular causes compared to placebo, and is it safe? (English)

Authors: Lanthier, Luc, Mutchmore, Alexandre, Plourde, Marc-Émile, Cauchon, Michel

Source: In La revue de médecine interne October 2024 45(10):667-668

Chez les patients présentant un syndrome coronarien aigu et ayant subi une intervention coronarienne percutanée avec des endoprothèses contemporaines et qui n’ont pas eu d’événement ischémique ou hémorragique pendant 1 mois sous traitement antiplaquettaire double, est-ce qu’un traitement par ticagrélor seul entre le 1er et le 12e mois diminue le risque de saignement cliniquement important tout en étant efficace pour prévenir les complications vasculaires comparativement au ticagrélor combiné à l’aspirine ?

Alternate Title: Among patients with acute coronary syndrome who underwent percutaneous coronary intervention with contemporary stents and had no ischemic or hemorrhagic events during 1 month on dual antiplatelet therapy, does treatment with ticagrelor alone between the 1st and 12th month reduce the risk of clinically relevant bleeding while remaining effective in preventing vascular complications compared to ticagrelor combined with aspirin? (English)

Authors: Lanthier, Luc, Couture, Étienne L., Plourde, Marc-Émile, Cauchon, Michel

Source: In La revue de médecine interne August 2024 45(8):519-520

Chez les sujets avec cardiopathie ischémique stable et ischémie modérée à sévère, est-ce que le cathétérisme cardiaque et la revascularisation coronarienne lorsque possible combinés à un traitement médical amènent un bénéfice clinique comparativement au traitement médical seul ?

Authors: Lanthier, Luc, Huard, Gabriel, Plourde, Marc-Émile, Cauchon, Michel

Source: Revue de médecine interne. 41(7):504-505

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117984712.0x000001&indx=1&recIds=ETOCvdc_100117984712.0x000001

Chez les femmes enceintes avec HTA préexistante légère, est-ce qu’une stratégie de traitement utilisant une cible de traitement < 140/90 mmHg comparativement à une surveillance sans traitement sauf si la TA > 160/105 mmHg réduit l’incidence de complications maternelles et périnatales tout en étant sécuritaire?

Alternate Title: In pregnant women with mild chronic hypertension, does a treatment strategy using a treatment target<140/90mmHg compared to watchful waiting unless BP>160/105mmHg reduce the incidence of maternal and perinatal complications while being safe? (English)

Authors: Lanthier, Luc, Sauvé, Nadine, Plourde, Marc-Émile, Cauchon, Michel

Source: In La revue de médecine interne August 2022 43(8):514-515

This result is not displayed to guests.
Login for full access.

Students' self-explanations while solving unfamiliar cases: the role of biomedical knowledge.

Authors: Chamberland, Martine¹, Mamede, Sílvia², St‐Onge, Christina³, Rivard, Marc‐Antoine¹, Setrakian, Jean¹, Lévesque, Annie³, Lanthier, Luc¹, Schmidt, Henk G², Rikers, Remy M J P²

Source: Medical Education; Nov2013, Vol. 47 Issue 11, p1109-1116, 8p, 4 Charts

This result is not displayed to guests.
Login for full access.

The influence of medical students' self-explanations on diagnostic performance.

Authors: Chamberland, Martine¹, St‐Onge, Christina¹, Setrakian, Jean¹, Lanthier, Luc¹, Bergeron, Linda², Bourget, Annick³, Mamede, Silvia⁴, Schmidt, Henk⁴, Rikers, Remy⁴

Source: Medical Education; Jul2011, Vol. 45 Issue 7, p688-695, 8p, 5 Charts

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.