Genetic retargeting of E3 ligases to enhance CAR T cell therapy

Authors: Lane, Isabel C., Kembuan, Gabriele, Carreiro, Jeannie, Kann, Michael C., Lin, William, Bouffard, Amanda A., Kreuzer, Johannes, Morris, Robert, Schneider, Emily M., Kim, Joanna Y., Zou, Charles, Salas-Benito, Diego, Gasser, Jessica A., Leick, Mark B., Słabicki, Mikołaj, Haas, Wilhelm, Maus, Marcela V., Jan, Max

Source: In Cell Chemical Biology 15 February 2024 31(2):338-348

SEAKER cells coordinate cellular immunotherapy with localized chemotherapy

Authors: Lane, Isabel C., Jan, Max

Source: In Trends in Pharmacological Sciences October 2022 43(10):804-805

A Lenalidomide-Inducible Suicide Switch for Gene- and Cell-Based Therapy

Authors: Lin, William, Sarkar, Ditsa, Kim, Joanna Y, Knudsen, Nelson H, Lane, Isabel C, Cheng, Andi, Kembaun, Gabriele, Kienka, Tamina, Carreiro, Jeannie, Bouffard, Amanda A, Maus, Marcela V, Manguso, Robert T, Jan, Max

Source: In Blood 2 November 2023 142 Supplement 1:4825-4825

Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7

Authors: Kann, Michael C., Schneider, Emily M., Almazan, Antonio J., Lane, Isabel C., Bouffard, Amanda A., Supper, Valentina M., Takei, Hana N., Tepper, Alexander, Leick, Mark B., Larson, Rebecca C., Ebert, Benjamin L., Maus, Marcela V., Jan, Max

Source: Leukemia; 20230101, Issue: Preprints p1-11, 11p