Exploring Candesartan, an angiotensin II receptor antagonist, as a novel inhibitor of NLRP3 inflammasome: alleviating inflammation in Neisseria gonorrhoeae infection

Authors: Wen-Yu Lin, Jin-Lian Tsui, Hsiao-Wen Chiu, Wei-Ting Wong, Chun‑Hsien Wu, Hsien-Ta Hsu, Chen-Lung Ho, Shan-Pei Yeh, Yerra Koteswara Rao, Ann Chen, Chien-Chun Wang, Chung-Hua Hsu, Oleg V. Chernikov, Kuo-Feng Hua, Lan-Hui Li

Source: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Angiotensin II receptor antagonist, Candesartan, NLRP3 inflammasome, Neisseria gonorrhoeae, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/ebd34357f8f3401aa2d43e4324d760d3

Cinnamaldehyde inhibits the NLRP3 inflammasome by preserving mitochondrial integrity and augmenting autophagy in Shigella sonnei-infected macrophages

Authors: Kuo-Feng Hua, Yu-Bei Lin, Hsiao-Wen Chiu, Wei-Ting Wong, Shuk-Man Ka, Chun-Hsien Wu, Wen-Yu Lin, Chien-Chun Wang, Chung-Hua Hsu, Hsien-Ta Hsu, Chen-Lung Ho, Lan-Hui Li

Source: Journal of Inflammation, Vol 21, Iss 1, Pp 1-15 (2024)

Subject Terms: Shigella sonnei, NLRP3 inflammasome, Cinnamaldehyde, Pyroptosis, Autophagy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1476-9255

Access URL: https://doaj.org/article/9386de0fff29441d99c710995bda777e

Cinnamaldehyde, A Bioactive Compound from the Leaves of Cinnamomum osmophloeum Kaneh, Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice by Inhibiting the NLRP3 Inflammasome

Authors: May-Lan Liu, Wei-Ting Wong, Yih-Ming Weng, Chen-Lung Ho, Hsien-Ta Hsu, Kuo-Feng Hua, Chun-Hsien Wu, Lan-Hui Li

Source: Journal of Physiological Investigation, Vol 67, Iss 3, Pp 139-152 (2024)

Subject Terms: autophagy, cinnamaldehyde, inflammatory bowel disease, nlrp3 inflammasome, Physiology, QP1-981, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/ejpi.EJPI-D-24-00017; https://doaj.org/toc/2950-6344; https://doaj.org/toc/2950-6352

Access URL: https://doaj.org/article/081eefa2dc1d4d1f86bfd2297a215263

Eggshell translucency in late-phase laying hens and its effect on egg quality and physiological indicators

Authors: He-Ling Ren, Xiao-Yu Zhao, Ke-Qian Di, Lan-Hui Li, Er-Ying Hao, Hui Chen, Rong-Yan Zhou, Chang-Sheng Nie, De-He Wang

Source: Frontiers in Veterinary Science, Vol 10 (2023)

Subject Terms: late-phase laying hen, eggshell translucency, egg quality, physiological indicator, calcium, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fvets.2023.1133752/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/cbf614a9516241d1a6ef0f4b87631375

The leaves of the seasoning plant Litsea cubeba inhibit the NLRP3 inflammasome and ameliorate dextran sulfate sodium-induced colitis in mice

Authors: Wei-Ting Wong, Chun-Hsien Wu, Lan-Hui Li, De-Yu Hung, Hsiao-Wen Chiu, Hsien-Ta Hsu, Chen-Lung Ho, Oleg V. Chernikov, Shu-Meng Cheng, Shih-Ping Yang, Chih-Hsin Chung, Kuo-Feng Hua, Chin-Fah Wang

Source: Frontiers in Nutrition, Vol 9 (2022)

Subject Terms: NLRP3 inflammasome, Litsea cubeba, macrophages, dextran sulfate sodium-induced colitis, cytokines, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2022.871325/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/ebf71b9c8394472985ce1b34aa56dfb2

Eucalyptus essential oils inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through reducing MAPK and NF-κB pathways

Authors: Chen-Lung Ho, Lan-Hui Li, Yueh-Chun Weng, Kuo-Feng Hua, Tz-Chuen Ju

Source: BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)

Subject Terms: Anti-inflammation, Eucalyptus essential oils, Macrophages, Cytokine, Lipopolysaccharide, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12906-020-02999-0; https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/d20b92716b46435eac42d5a99d3003fa

Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory Activity

Authors: Wen-Yu Lin, Lan-Hui Li, Ya-Yun Hsiao, Wei-Ting Wong, Hsiao-Wen Chiu, Hsien-Ta Hsu, Yi-Jen Peng, Chen-Lung Ho, Oleg V. Chernikov, Shu-Meng Cheng, Shih-Ping Yang, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: NLRP3 inflammasome, candesartan, angiotensin II receptor antagonist, drug repositioning, peritonitis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.870627/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/dab1c99510b34f61b9f8d9dc31c1a79e

Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction

Authors: Chun-Hsien Wu, Chin Heng Gan, Lan-Hui Li, Jen-Che Chang, Shin-Tai Chen, Mridula P. Menon, Shu-Meng Cheng, Shih-Ping Yang, Chen-Lung Ho, Oleg V. Chernikov, Chi-Hung Lin, Yulin Lam, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: NLRP3 inflammasome, conjugated polyenes, autophagy, mitochondria, peritonitis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.738591/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2e4a50d8a0a74080ac3fc0e44d9c169c

Identification of a Goat Intersexuality-Associated Novel Variant Through Genome-Wide Resequencing and Hi-C

Authors: Guang-Xin E, Dong-Ke Zhou, Zhu-Qing Zheng, Bai-Gao Yang, Xiang-Long Li, Lan-Hui Li, Rong-Yan Zhou, Wen-Hui Nai, Xun-Ping Jiang, Jia-Hua Zhang, Qiong-Hua Hong, Yue-Hui Ma, Ming-Xing Chu, Hui-Jiang Gao, Yong-Ju Zhao, Xing-Hai Duan, Yong-Meng He, Ri-Su Na, Yan-Guo Han, Yan Zeng, Yu Jiang, Yong-Fu Huang

Source: Frontiers in Genetics, Vol 11 (2021)

Subject Terms: intersexuality, genome-wide selection, Hi-C, copy number variant, translocation, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2020.616743/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/d7c0a5ac4f0245119af286a769519922

A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction

Authors: Chun-Hsien Wu, Chin Heng Gan, Lan-Hui Li, Jen-Che Chang, Shin-Tai Chen, Mridula P. Menon, Shu-Meng Cheng, Shih-Ping Yang, Chen-Lung Ho, Oleg V. Chernikov, Chi-Hung Lin, Yulin Lam, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: NLRP3 inflammasome, conjugated polyenes, autophagy, mitochondria, peritonitis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.607564/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b3bedefcc0aa4acca5f8333fdfc9d21f

Critical Role for the NLRP3 Inflammasome in Mediating IL-1β Production in Shigella sonnei-Infected Macrophages

Authors: Lan-Hui Li, Tzu-Ling Chen, Hsiao-Wen Chiu, Chung-Hua Hsu, Chien-Chun Wang, Tzu-Ting Tai, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, Wen-Chiuan Tsai, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: shigellosis, NLRP3 inflammasome, macrophages, P2X7 receptor, mitochondria, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01115/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/df481b25e45b40a797e039b664e6e64e

Immunomodulatory Properties of Polysaccharides from the Coral Pseudopterogorgia americana in Macrophages

Authors: Oleg V. Chernikov, Hsiao-Wen Chiu, Lan-Hui Li, Maxim S. Kokoulin, Valentina I. Molchanova, Hsien-Ta Hsu, Chen-Lung Ho, Kuo-Feng Hua

Source: Cells, Vol 10, Iss 12, p 3531 (2021)

Subject Terms: Pseudopterogorgia americana, polysaccharide, macrophages, immune modulation, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/12/3531; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/747e9565a7bd4f78a22b1b0d2ac7711a

A GalNAc/Gal-specific lectin from the sea mussel Crenomytilus grayanus modulates immune response in macrophages and in mice

Authors: Oleg V. Chernikov, Wei-Ting Wong, Lan-Hui Li, Irina V. Chikalovets, Valentina I. Molchanova, Shih-Hsiung Wu, Jiahn-Haur Liao, Kuo-Feng Hua

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/23e3ea93929e40c1a607fc0ae4e865a8

Mechanistic Insight Into the Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae in Macrophages

Authors: Lan-Hui Li, Jia-Sing Lin, Hsiao-Wen Chiu, Wen-Yu Lin, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, May-Lan Liu, Jen-Che Chang, Chung-Hua Hsu, Ann Chen, Shuk-Man Ka, Hong-Wei Gao, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: Neisseria gonorrhoeae, NLRP3 inflammasome, macrophages, signal transduction, bactericidal activity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01815/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/99e5dcda26144f25b5a723ff3f967933

Repositioning of the β-Blocker Carvedilol as a Novel Autophagy Inducer That Inhibits the NLRP3 Inflammasome

Authors: Wei-Ting Wong, Lan-Hui Li, Yerra Koteswara Rao, Shih-Ping Yang, Shu-Meng Cheng, Wen-Yu Lin, Cheng-Chung Cheng, Ann Chen, Kuo-Feng Hua

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: Carvedilol, NLRP3 inflammasome, autophagy, mitochondria, peritonitis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01920/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/65b8aa6978a243ed9aec7d7a6fb54137

Synthetic 4-Hydroxy Auxarconjugatin B, a Novel Autophagy Inducer, Attenuates Gouty Inflammation by Inhibiting the NLRP3 Inflammasome

Authors: Chih-Yu Hsieh, Lan-Hui Li, Yulin Lam, Zhanxiong Fang, Chin Heng Gan, Yerra Koteswara Rao, Hsiao-Wen Chiu, Wei-Ting Wong, Tz-Chuen Ju, Fang-Hsin Chen, Oleg V. Chernikov, May-Lan Liu, Chung-Hua Hsu, Kuo-Feng Hua

Source: Cells, Vol 9, Iss 2, p 279 (2020)

Subject Terms: 4-hydroxy auxarconjugatin b, nlrp3 inflammasome, mitochondria, autophagy, gouty inflammation, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/2/279; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/724b7b5f8c884c71b2c2212ec09c509f

A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP.

Authors: Lan-Hui Li, Tz-Chuen Ju, Chih-Yu Hsieh, Wei-Chih Dong, Wan-Tze Chen, Kuo-Feng Hua, Wei-Jung Chen

Source: PLoS ONE, Vol 12, Iss 7, p e0182057 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5531531?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49c6caee184945d59606c208ae57c072

Corrigendum to 'Changes in the six most common sequence types of Neisseria gonorrhoeae, including ST4378, identified by surveillance of antimicrobial resistance in northern Taiwan from 2006 to 2013' [J Microbiol Immunol Infect 49 (5) (2016) 708–716]

Authors: Ching-Wai Cheng, Lan-Hui Li, Chen-Yi Su, Shu-Ying Li, Muh-Yong Yen

Source: Journal of Microbiology, Immunology and Infection, Vol 51, Iss 3, p 422 (2018)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1684118217300063; https://doaj.org/toc/1684-1182

Access URL: https://doaj.org/article/b6a298ad566b4c04b472a9487bcbb570

Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells.

Authors: Lan-Hui Li, Ping Wu, Jen-Yi Lee, Pei-Rong Li, Wan-Yu Hsieh, Chao-Chi Ho, Chen-Lung Ho, Wan-Jiun Chen, Chien-Chun Wang, Muh-Yong Yen, Shun-Min Yang, Huei-Wen Chen

Source: PLoS ONE, Vol 9, Iss 8, p e104203 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4126702?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f38d989bcd034b2b82b732db08a8e9e6

Non-cytotoxic nanomaterials enhance antimicrobial activities of cefmetazole against multidrug-resistant Neisseria gonorrhoeae.

Authors: Lan-Hui Li, Muh-Yong Yen, Chao-Chi Ho, Ping Wu, Chien-Chun Wang, Pawan Kumar Maurya, Pai-Shan Chen, Wei Chen, Wan-Yu Hsieh, Huei-Wen Chen

Source: PLoS ONE, Vol 8, Iss 5, p e64794 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3660602?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2f881afcc8f54221ab0e1b25195574cb