Design and screening of novel molecular compounds targeting lactate dehydrogenase of Babesia microti

Authors: Wanxin Luo, Long Yu, Shiyu Lu, Yuxin Yu, Yidan Bai, Sen Wang, Dongfang Li, Zhen Han, Yaxin Zheng, Fangjie Li, Junlong Zhao, Lan He

Source: Parasites & Vectors, Vol 18, Iss 1, Pp 1-11 (2025)

Subject Terms: Babesia microti, Lactate dehydrogenase, Compound, Computer-aided drug design, Surface plasmon resonance, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1756-3305

Access URL: https://doaj.org/article/f8356447dbf74127bad1a647da2a5c06

Evaluation of suitability of CO2 geologic storage in deep saline aquifers in Lindian area of Songliao Basin

Authors: Yongfa MA, Junling DONG, Xu WANG, Lan HE, Xuejun ZHOU, Ling LIU, Guang LIU, Zhenzhen SHI, Guannan CAO, Yan LIU, Xiuhai LI, Tian LIU, Tao ZHAN, Chang LI

Source: Shuiwen dizhi gongcheng dizhi, Vol 52, Iss 1, Pp 238-248 (2025)

Subject Terms: co2, geological storage, suitability evaluation, lindian area, Geology, QE1-996.5

File Description: electronic resource

Relation: https://doaj.org/toc/1000-3665

Access URL: https://doaj.org/article/b8d146475b864a4b82c474b27188703f

Phosphoenolpyruvate carboxylase (PEPC) is essential for the glycolytic pathway and parasite proliferation in Babesia gibsoni

Authors: Dong-Fang Li, Ling-Na Wang, Yi-Dan Bai, Yu-Xin Yu, Xing Lu, Xing-Ai Guan, Fang-Jie Li, Sen Wang, Lan He, Jun-Long Zhao

Source: Animal Diseases, Vol 4, Iss 1, Pp 1-12 (2024)

Subject Terms: Babesia gibsoni, Phosphoenolpyruvate, Phosphoenolpyruvate carboxylase, Malate, Aspartate, Veterinary medicine, SF600-1100, Public aspects of medicine, RA1-1270

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Relation: https://doaj.org/toc/2731-0442

Access URL: https://doaj.org/article/55a123763bf74127aab22c249bc18186

Establishment of the auxin inducible degron system for Babesia duncani: a conditional knockdown tool to study precise protein regulation in Babesia spp.

Authors: Bo Chen, Qi Zhang, Sen Wang, Xing-ai Guan, Wan-xin Luo, Dong-fang Li, Yue He, Shu-jing Huang, Ya-ting Zhou, Jun-long Zhao, Lan He

Source: Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)

Subject Terms: Babesia duncani, Conditional knockdown system, Auxin-inducible degron, Protein degradation, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1756-3305

Access URL: https://doaj.org/article/efecd796b72641bb9d320d31a351979f

Homoharringtonine: mechanisms, clinical applications and research progress

Authors: Wen Wang, Lan He, Ting Lin, Fulan Xiang, Yibin Wu, Fangliang Zhou, Yingchun He

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: homoharringtonine, hematological disorders, antitumor activity, pharmacological mechanisms, clinical applications, cancer treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1522273/full; https://doaj.org/toc/2234-943X

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Retraction notice to 'Tfh cells potential dual role in cancer: A perspective' [Heliyon 10/19 2024 e37502]

Authors: Muhammad Yaqub, Muhammad Salman Pathan, Soumyabrata Dev, Lan He

Source: Heliyon, Vol 11, Iss 1, Pp e41367- (2025)

Subject Terms: Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024173987; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/8a15e11549754109b1465e135f863a6c

Evodiamine inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells via the SRC/ERBB2-mediated MAPK/ERK signaling pathway

Authors: Jie Liu, Lan He, Wenqing Zhang, Yinggang Tang, Jingying Fan, Yingchun He

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)

Subject Terms: Nasopharyngeal carcinoma, Evodiamine, SRC, ERBB2, MAPK/ERK signaling pathway, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/dd9d35a2b116443c996e01e325c16baa

Deep Learning-Based Artificial Intelligence Model for Automatic Carotid Plaque Identification

Authors: Lan HE, E SHEN, Zekun YANG, Ying ZHANG, Yudong WANG, Weidao CHEN, Yitong WANG, Yongming HE

Source: Zhongguo yiliao qixie zazhi, Vol 48, Iss 4, Pp 361-366 (2024)

Subject Terms: single-input bcnn-resnet network model, carotid ultrasound, deep learning, Computer applications to medicine. Medical informatics, R858-859.7, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1671-7104

Access URL: https://doaj.org/article/04e6afd03bf74c8f863fe19831ad53da

Intelligent breast cancer diagnosis with two-stage using mammogram images

Authors: Muhammad Yaqub, Feng Jinchao, Nazish Aijaz, Shahzad Ahmed, Atif Mehmood, Hao Jiang, Lan He

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Subject Terms: Breast cancer, Mammograms, Atrous convolution-based attentive and adaptive Trans-Res-UNet, Modified mussel length-based eurasian oystercatcher optimization, Atrous convolution based attentive and adaptive multi-scale DenseNet, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3e4acbc1dc4e4f3da10f55051a90cbfe

JAK inhibitors attenuate hyperactivation of nonswitched memory B cells in rheumatoid arthritis patients in remission

Authors: Jing Luo, Jing Zhang, Bomiao Ju, Yanhua Wang, Nan Hu, Qian Li, Qianyun Xu, Dan Pu, Zhiming Hao, Yongwei Huo, Xiaohong Lv, Lan He

Source: Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)

Subject Terms: Rheumatoid arthritis, Janus kinase inhibitors, B-cell subpopulations, CD40, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1478-6362

Access URL: https://doaj.org/article/0c8443bcd4394fdf9fe3d82e7be1bdab

Tfh cells potential dual role in cancer: A perspective

Authors: Muhammad Yaqub, Muhammad Salman Pathan, Soumyabrata Dev, Lan He

Source: Heliyon, Vol 10, Iss 19, Pp e37502- (2024)

Subject Terms: Tfh cells, Cancer, Tumor microenvironment, Oncology, Cytokines, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024135335; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/d641c03e7d944e0c984c27a8605a7d81

The anti-obesity effects of polyphenols: a comprehensive review of molecular mechanisms and signal pathways in regulating adipocytes

Authors: Lan He, Zhan Su, Shuangshuang Wang

Source: Frontiers in Nutrition, Vol 11 (2024)

Subject Terms: polyphenol, obesity, adipose tissue, antioxidant effect, gut microbiota, inflammatory reaction, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2024.1393575/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/8d24c0b6226a41f89b36442bc7590a1a

Association between serum estradiol levels and abdominal aortic calcification in postmenopausal woman: a cross-sectional study

Authors: Lan He, Xu Li, E Shen, Yong-Ming He

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: abdominal aortic calcification, estradiol, NHANES, postmenopausal woman, cross-sectional study, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1411803/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/da70991c06a34492a3346beddfa0ecee

Global trends in research of nasopharyngeal carcinoma: a bibliometric and visualization analysis

Authors: Guilin An, Jie Liu, Ting Lin, Lan He, Yingchun He

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: nasopharyngeal carcinoma, bibliometric analysis, research trends, VOSviewer, CiteSpace, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1392245/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/348d3d0e985940c99383217fe7128ccf

Clinical Value of Spectral Imaging Combined with MAR for CTA after Embolization of Intracranial Aneurysms

Authors: Qinwen YAN, Yuxiang WANG, Jun ZHANG, Lan HE, Gang HU, Minchao XIONG, Junxiang QIN, Xuegang YUAN

Source: CT Lilun yu yingyong yanjiu, Vol 33, Iss 2, Pp 182-188 (2024)

Subject Terms: tomography, x-ray computed, spectral imaging, embolization of intracranial aneurysms, metal artifact, Geophysics. Cosmic physics, QC801-809, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1004-4140

Access URL: https://doaj.org/article/610ca0be357248d7b7bbe455c1489e30

Suppressing MTERF3 inhibits proliferation of human hepatocellular carcinoma via ROS-mediated p38 MAPK activation

Authors: Zhihai Zheng, Youjuan Zhao, Hongjia Yu, Tingting Wang, Jinhai Li, Liang Xu, Chunming Ding, Lan He, Lijun Wu, Zhixiong Dong

Source: Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/0da64d4cd60a4b01b799d675772cdd3a

COX6C expression driven by copy amplification of 8q22.2 regulates cell proliferation via mediation of mitosis by ROS-AMPK signaling in lung adenocarcinoma

Authors: Shuanghui Liu, Fanggui Shao, Yourong Wang, Yurui Zhang, Hongjia Yu, Ningxin Zhang, Lan He, Qingran Kong, Hao Jiang, Zhixiong Dong

Source: Cell Death and Disease, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/db50300ee44c49279b58c5722e126dc4

Synthesis of Headful Packaging Phages Through Yeast Transformation-Associated Recombination

Authors: Cheng Lu, Lan He, Yangyijun Guo, Tingting Wang, Yanrui Ye, Zhanglin Lin

Source: Viruses, Vol 17, Iss 1, p 45 (2024)

Subject Terms: headful packaging, synthetic phage, yeast transformation-associated recombination, Pseudomonas aeruginosa phage, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/17/1/45; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/03b8b7f9630f4a7bba7c616d3bd12676

The Influence of Ice Accretion on the Thermodynamic Performance of a Scientific Balloon: A Simulation Study

Authors: Qiang Liu, Lan He, Yanchu Yang, Kaibin Zhao, Tao Li, Rongchen Zhu, Yanqing Wang

Source: Aerospace, Vol 11, Iss 11, p 899 (2024)

Subject Terms: scientific balloon, ice accretion, thermodynamic performance, modeling and simulation, Motor vehicles. Aeronautics. Astronautics, TL1-4050

File Description: electronic resource

Relation: https://www.mdpi.com/2226-4310/11/11/899; https://doaj.org/toc/2226-4310

Access URL: https://doaj.org/article/ace3e3c1d07d4233ade09c0a14c1b15b

A deep learning algorithm to identify carotid plaques and assess their stability

Authors: Lan He, Zekun Yang, Yudong Wang, Weidao Chen, Le Diao, Yitong Wang, Wei Yuan, Xu Li, Ying Zhang, Yongming He, E. Shen

Source: Frontiers in Artificial Intelligence, Vol 7 (2024)

Subject Terms: deep learning, carotid plaque stability, ultrasound, convolutional neural network, BCNN-ResNet algorithms, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frai.2024.1321884/full; https://doaj.org/toc/2624-8212

Access URL: https://doaj.org/article/633b78ea87ed41aa9467d609b8018f6e