Genetic mechanisms of co-emergence of INH-resistant Mycobacterium tuberculosis strains during the standard course of antituberculosis therapy

Authors: Ketema Tafess, Timothy Ting-Leung Ng, Kingsley King-Gee Tam, Kenneth Siu-Sing Leung, Jake Siu-Lun Leung, Lam-Kwong Lee, Hiu Yin Lao, Chloe Toi-Mei Chan, Wing-Cheong Yam, Samson Sai Yin Wong, Terrence Chi-Kwong Lau, Gilman Kit-Hang Siu

Source: Microbiology Spectrum, Vol 12, Iss 4 (2024)

Subject Terms: isoniazid resistance, Mycobacterium tuberculosis, whole-genome sequencing, transformation, antituberculosis treatment, protein modeling, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/3ffa64bb1abf4ad388be8732347d351c

Probable airborne transmission of Burkholderia pseudomallei causing an urban outbreak of melioidosis during typhoon season in Hong Kong, China

Authors: Wing-Gi Wu, Marcus Ho-Hin Shum, Ivan Tak-Fai Wong, Kelvin Keru Lu, Lam-Kwong Lee, Jake Siu-Lun Leung, Hiu-Yin Lao, Annie Wing-Tung Lee, Pak-Ting Hau, Chloe Toi-Mei Chan, Harmen Fung-Tin Wong, Sharon Ka-Yee Fung, Sally Choi-Ying Wong, Iain Chi-Fung Ng, Timothy Ting-Leung Ng, Ning Chow, Alex Yat-Man Ho, Mei Fan Hung, Franklin Wang-Ngai Chow, Maureen Mo-Lin Wong, Wing-Kin To, Tommy Tsan-Yuk Lam, Kristine Shik Luk, Gilman Kit-Hang Siu

Source: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

Subject Terms: Melioidosis, Burkholderia pseudomallei, core genome-multilocus sequence typing, airborne transmission, urban outbreak, typhoon, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/c3a8a233eced457a8aaf656ab19f7432

Transmission Patterns of Co-Circulation of Omicron Sub-Lineages in Hong Kong SAR, China, a City with Rigorous Social Distancing Measures, in 2022

Authors: Ning Chow, Teng Long, Lam-Kwong Lee, Ivan Tak-Fai Wong, Annie Wing-Tung Lee, Wing-Yin Tam, Harmen Fung-Tin Wong, Jake Siu-Lun Leung, Franklin Wang-Ngai Chow, Kristine Shik Luk, Alex Yat-Man Ho, Jimmy Yiu-Wing Lam, Miranda Chong-Yee Yau, Tak-Lun Que, Kam-Tong Yip, Viola Chi-Ying Chow, River Chun-Wai Wong, Bobo Wing-Yee Mok, Hong-lin Chen, Gilman Kit-Hang Siu

Source: Viruses, Vol 16, Iss 6, p 981 (2024)

Subject Terms: COVID-19, Omicron, co-circulation, social distancing, quarantine arrangements, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/6/981; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/3f8ca797a0c8431c91c7b7ba2953aa33

A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis

Authors: Rahim Rajwani, Chala Galata, Annie Wing Tung Lee, Pui-Kin So, Kenneth Siu Sing Leung, Kingsley King Gee Tam, Sheeba Shehzad, Timothy Ting Leung Ng, Li Zhu, Hiu Yin Lao, Chloe Toi-Mei Chan, Jake Siu-Lun Leung, Lam-Kwong Lee, Kin Chung Wong, Wing Cheong Yam, Gilman Kit-Hang Siu

Source: Virulence, Vol 13, Iss 1, Pp 1088-1100 (2022)

Subject Terms: Hypervirulence, Mycobacterium tuberculosis, multi-omics, tuberculous meningitis, RNA sequencing, LC-MS/MS, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/2150-5594; https://doaj.org/toc/2150-5608

Access URL: https://doaj.org/article/ecbfa38fe16745f083c01d1197a0e041

Cocirculation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong

Authors: Kin-Hang Kok, Shuk-Ching Wong, Wan-Mui Chan, Wen Lei, Allen Wing-Ho Chu, Jonathan Daniel Ip, Lam-Kwong Lee, Ivan Tak-Fai Wong, Hazel Wing-Hei Lo, Vincent Chi-Chung Cheng, Alex Yat-Man Ho, Bosco Hoi-Shiu Lam, Herman Tse, David Lung, Kenneth Ho-Leung Ng, Albert Ka-Wing Au, Gilman Kit-Hang Siu, Kwok-Yung Yuen

Source: Emerging Microbes and Infections, Vol 0, Iss 0, Pp 1-39 (2022)

Subject Terms: animal, coronavirus, hamster, interspecies, transmission, sars-cov-2, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/d65402ffd340413aaf16c752f2580ee2

Identification of microbial community in the urban environment: The concordance between conventional culture and nanopore 16S rRNA sequencing

Authors: Annie Wing-Tung Lee, Chloe Toi-Mei Chan, Lily Lok-Yee Wong, Cheuk-Yi Yip, Wing-Tung Lui, Kai-Chun Cheng, Jake Siu-Lun Leung, Lam-Kwong Lee, Ivan Tak-Fai Wong, Timothy Ting-Leung Ng, Hiu-Yin Lao, Gilman Kit-Hang Siu

Source: Frontiers in Microbiology, Vol 14 (2023)

Subject Terms: urban microbiome, nanopore sequencing, 16S rRNA gene sequencing, taxonomic classifiers, conventional culture, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2023.1164632/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/b6a0d455b401437584883c2cf10b3f02

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

Authors: Bobo Wing-Yee Mok, Honglian Liu, Shaofeng Deng, Jiayan Liu, Anna Jinxia Zhang, Siu-Ying Lau, Siwen Liu, Rachel Chun-Yee Tam, Conor J. Cremin, Timothy Ting-Leung Ng, Jake Siu-Lun Leung, Lam-Kwong Lee, Pui Wang, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Kwok-Hung Chan, Kwok-Yung Yuen, Gilman Kit-Hang Siu, Honglin Chen

Source: Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/e1d11d48a5164a96b5e36a1d1ccb137f

Territorywide Study of Early Coronavirus Disease Outbreak, Hong Kong, China

Authors: Kenneth Siu-Sing Leung, Timothy Ting-Leung Ng, Alan Ka-Lun Wu, Miranda Chong-Yee Yau, Hiu-Yin Lao, Ming-Pan Choi, Kingsley King-Gee Tam, Lam-Kwong Lee, Barry Kin-Chung Wong, Alex Yat Man Ho, Kam-Tong Yip, Kwok-Cheung Lung, Raymond Wai-To Liu, Eugene Yuk-Keung Tso, Wai-Shing Leung, Man-Chun Chan, Yuk-Yung Ng, Kit-Man Sin, Kitty Sau-Chun Fung, Sandy Ka-Yee Chau, Wing-Kin To, Tak-Lun Que, David Ho-Keung Shum, Shea Ping Yip, Wing Cheong Yam, Gilman Kit-Hang Siu

Source: Emerging Infectious Diseases, Vol 27, Iss 1, Pp 196-204 (2021)

Subject Terms: novel coronavirus, COVID-19, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, viruses, respiratory infections, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/27/1/20-1543_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/9edf4aa73a2d47e994555d785faa68a7

Complementation of contact tracing by mass testing for successful containment of beta COVID-19 variant (SARS-CoV-2 VOC B.1.351) epidemic in Hong Kong

Authors: Vincent Chi-Chung Cheng, Gilman Kit-Hang Siu, Shuk-Ching Wong, Albert Ka-Wing Au, Cecilia Suk-Fun Ng, Hong Chen, Xin Li, Lam-Kwong Lee, Jake Siu-Lun Leung, Kelvin Keru Lu, Hazel Wing-Hei Lo, Evelyn Yin-Kwan Wong, Shik Luk, Bosco Hoi-Shiu Lam, Wing-Kin To, Rodney Allan Lee, David Christopher Lung, Mike Yat-Wah Kwan, Herman Tse, Shuk-Kwan Chuang, Kelvin Kai-Wang To, Kwok-Yung Yuen

Source: The Lancet Regional Health. Western Pacific, Vol 17, Iss , Pp 100281- (2021)

Subject Terms: SARS-CoV-2, Variants of Concern, Contact tracing, Mass testing, Phylogenetic analysis, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666606521001905; https://doaj.org/toc/2666-6065

Access URL: https://doaj.org/article/02b6eafe67bd4420ab377076c584545d

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Authors: Gilman Kit-Hang Siu, Lam-Kwong Lee, Kenneth Siu-Sing Leung, Jake Siu-Lun Leung, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Kingsley King-Gee Tam, Hiu-Yin Lao, Alan Ka-Lun Wu, Miranda Chong-Yee Yau, Yvette Wai-Man Lai, Kitty Sau-Chun Fung, Sandy Ka-Yee Chau, Barry Kin-Chung Wong, Wing-Kin To, Kristine Luk, Alex Yat-Man Ho, Tak-Lun Que, Kam-Tong Yip, Wing Cheong Yam, David Ho-Keung Shum, Shea Ping Yip

Source: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2497-2500 (2020)

Subject Terms: COVID-19, SARS-CoV-2, whole genome sequencing, Phylogeny, outbreak, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/9d17b7af308a4b93bee42e497c57cd1f

Territorywide Study of Early Coronavirus Disease Outbreak, Hong Kong, China.

Authors: Siu-Sing Leung, Kenneth¹, Ting-Leung Ng, Timothy², Ka-Lun Wu, Alan³, Chong-Yee Yau, Miranda³, Hiu-Yin Lao², Ming-Pan Choi², King-Gee Tam, Kingsley¹, Lam-Kwong Lee², Kin-Chung Wong, Barry⁴, Yat-Man Ho, Alex⁵, Kam-Tong Yip⁶, Kwok-Cheung Lung³, Wai-To Liu, Raymond⁷, Yuk-Keung Tso, Eugene⁴, Wai-Shing Leung⁵, Man-Chun Chan⁵, Yuk-Yung Ng⁶, Kit-Man Sin⁶, Sau-Chun Fung, Kitty⁴, Ka-Yee Chau, Sandy⁴

Source: Emerging Infectious Diseases; Jan2021, Vol. 27 Issue 1, p196-204, 9p

Long-Read Sequencing with Hierarchical Clustering for Antiretroviral Resistance Profiling of Mixed Human Immunodeficiency Virus Quasispecies.

Authors: Ting-Leung Ng, Timothy, Junhao Su, Hiu-Yin Lao, Wui-Wang Lui, Chloe Toi-Mei Chan, Amy Wing-Sze Leung, Hoi-Ching Jim, Stephanie, Lam-Kwong Lee, Shehzad, Sheeba, King-Gee Tam, Kingsley, Siu-Sing Leung, Kenneth, Tang, Forrest, Wing-Cheong Yam, Ruibang Luo, Kit-Hang Siu, Gilman

Source: Clinical Chemistry; Oct2023, Vol. 69 Issue 10, p1174-1185, 12p

Identification of microbial community in the urban environment: The concordance between conventional culture and nanopore 16S rRNA sequencing.

Authors: Wing-Tung Lee, Annie, Toi-Mei Chan, Chloe, Lok-Yee Wong, Lily, Cheuk-Yi Yip, Wing-Tung Lui, Kai-Chun Cheng, Siu-Lun Leung, Jake, Lam-Kwong Lee, Tak-Fai Wong, Ivan, Ting-Leung Ng, Timothy, Hiu-Yin Lao, Gilman, Kit-Hang Siu

Source: Frontiers in Microbiology; 2023, p1-11, 11p

Subject Terms: RIBOSOMAL RNA, MICROBIAL communities, BUILT environment, BACTERIAL diversity, BACTERIAL cultures, CULTURE

A multi-omics investigation into the mechanisms of hyper-virulence in Mycobacterium tuberculosis.

Authors: Rajwani, Rahim, Galata, Chala, Annie Wing Tung Lee, Pui-Kin So, Kenneth Siu Sing Leung, Kingsley King Gee Tam, Shehzad, Sheeba, Timothy Ting Leung Ng, Li Zhu, Hiu Yin Lao, Chloe Toi-Mei Chan, Jake Siu-Lun Leung, Lam-Kwong Lee, Kin Chung Wong, Wing Cheong Yam, Gilman Kit-Hang Siu

Source: Virulence; Dec2022, Vol. 13 Issue 1, p1088-1100, 13p

Fibrocartilaginous embolism: an under-recognised cause of young spinal stroke.

Authors: Nagaratnam, Sai Adithya¹ sai@nagaratnam.net, Lam Kwong Lee, Raymond², Sturm, Jonathan^1,3

Source: Practical Neurology. Aug2022, Vol. 22 Issue 4, p1-5. 5p.

Subject Terms: *CARTILAGE, *SPINAL cord diseases, *MAGNETIC resonance imaging, *EMBOLISMS, *DISEASE complications

Will a new clade of SARS-CoV-2 imported into the community spark a fourth wave of the COVID-19 outbreak in Hong Kong?

Authors: Kit-Hang Siu, Gilman, Lam-Kwong Lee, Siu-Sing Leung, Kenneth, Jake Siu-Lun Leung, Ting-Leung Ng, Timothy, Chloe Toi-Mei Chan, Tam, Kingsley King-Gee, Hiu-Yin Lao, Ka-Lun Wu, Alan, Chong-Yee Yau, Miranda, Yvette Wai-Man Lai, Sau-Chun Fung, Kitty, Ka-Yee Chau, Sandy, Kin-Chung Wong, Barry, Wing-Kin To, Luk, Kristine, Yat-Man Ho, Alex, Tak-Lun Que, Kam-Tong Yip, Wing Cheong Yam

Source: Emerging Microbes & Infections; 2020, Vol. 9 Issue 1, p2497-2500, 4p

Acute disseminated encephalomyelitis with bilateral optic neuritis following ChAdOx1 COVID-19 vaccination

Authors: Sai A. Nagaratnam, Alex C. Ferdi, John Leaney, Raymond Lam Kwong Lee, Yun Tae Hwang, Robert Heard

Source: BMC Neurology, Vol 22, Iss 1, Pp 1-7 (2022)

Subject Terms: Acute disseminated encephalomyelitis, Oxford Astra Zeneca coronavirus disease 2019 vaccine, Severe acute respiratory syndrome coronavirus 2, Demyelination, Case report, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/3004ae235e434401bb2faead8d655aa6