USP14 is crucial for proteostasis regulation and α-synuclein degradation in human SH-SY5Y dopaminergic cells

Authors: Srinivasan, Vignesh ^{a, b}, Soliymani, Rabah ^{a, c}, Ivanova, Larisa ^d, Eriksson, Ove ^{a, b}, Peitsaro, Nina ^a, Lalowski, Maciej ^{a, c, e}, Karelson, Mati ^d, Lindholm, Dan ^{a, b, f, ⁎}

Source: In Heliyon 15 February 2025 11(3)

The structure and function of YTHDF epitranscriptomic m6A readers

Authors: Sikorski, Vilbert, Selberg, Simona, Lalowski, Maciej, Karelson, Mati, Kankuri, Esko

Source: Trends in pharmacological sciences. 44(6):335-353

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190034178.0x000001&indx=1&recIds=ETOCvdc_100190034178.0x000001

Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social defeat

Authors: González Ibáñez, Fernando, Halvorson, Torin, Sharma, Kaushik, McKee, Chloe Grace, Carrier, Micaël, Picard, Katherine, Vernoux, Nathalie, Bisht, Kanchan, Deslauriers, Jessica, Lalowski, Maciej, Tremblay, Marie-Ève

Source: In Brain Behavior and Immunity November 2023 114:383-406

Minocycline treatment improves cognitive and functional plasticity in a preclinical mouse model of major depressive disorder

Authors: Poggini, Silvia, Banqueri, Maria, Ciano Albanese, Naomi, Golia, Maria Teresa, Ibáñez, Fernando González, Limatola, Cristina, Fuhrmann, Martin, Lalowski, Maciej, Tremblay, Marie-Eve, Maggi, Laura, Kaminska, Bozena, Branchi, Igor

Source: In Behavioural Brain Research 12 March 2023 441

Molecular puzzle of insulin: structural assembly pathways and their role in diabetes.

Authors: Urbaniak, Edyta, Henry, Sara, Lalowski, Maciej, Borowiak, Malgorzata

Source: Frontiers in Cell & Developmental Biology; 2025, p1-14, 14p

Subject Terms: INSULIN, DIABETES, PROINSULIN, PROTEIN folding, MOLECULAR chaperones, ENDOPLASMIC reticulum, CARBOHYDRATE metabolism

Proteomic Profiling of Leukocytes Reveals Dysregulation of Adhesion and Integrin Proteins in Chronic Kidney Disease-Related Atherosclerosis

Authors: Tracz, Joanna, Handschuh, Luiza, Lalowski, Maciej, Marczak, Łukasz, Kostka-Jeziomy, Katarzyna, Perek, Bartlomiej, Wanic-Kossowska, Maria, Podkowińska, Alina, Tykarski, Andrzej, Formanowicz, Dorota

Source: Journal of proteome research. 20(6):3053-3067

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626773939&indx=1&recIds=ETOCRN626773939

Epicardial transplantation of atrial appendage micrograft patch salvages myocardium after infarction

Authors: Xie, Yanbo, Lampinen, Milla, Takala, Juuso, Sikorski, Vilbert, Soliymani, Rabah, Tarkia, Miikka, Lalowski, Maciej, Mervaala, Eero, Kupari, Markku, Zheng, Zhe, Hu, Shengshou, Harjula, Ari, Kankuri, Esko

Source: In Journal of Heart and Lung Transplantation July 2020 39(7):707-718

Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy

Authors: Srinivasan, Vignesh, Bruelle, Celine, Scifo, Enzo, Pham, Dan Duc, Soliymani, Rabah, Lalowski, Maciej, Lindholm, Dan

Source: In iScience 24 January 2020 23(1)

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

Authors: Pham, Dan, Bruelle, Céline, Do, Hai, Pajanoja, Ceren, Jin, Congyu, Srinivasan, Vignesh, Olkkonen, Vesa, Eriksson, Ove, Jauhiainen, Matti, Lalowski, Maciej, Lindholm, Dan

Source: Cell death and disease. 10(7):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184312578.0x000001&indx=1&recIds=ETOCvdc_100184312578.0x000001

Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration

Authors: Brackhan, Mirjam, Calza, Giulio, Lundgren, Kristiina, Bascuñana, Pablo, Brüning, Thomas, Soliymani, Rabah, Kumar, Rakesh, Abelein, Axel, Baumann, Marc, Lalowski, Maciej, Pahnke, Jens

Source: EMBO reports. 23(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194584423.0x000001&indx=1&recIds=ETOCvdc_100194584423.0x000001

Unveiling the Function of the Mitochondrial Filament-Forming Protein LACTB in Lipid Metabolism and Cancer.

Authors: Cascone, Annunziata¹ (AUTHOR) sonia.cascone@helsinki.fi, Lalowski, Maciej² (AUTHOR) maciej.lalowski@helsinki.fi, Lindholm, Dan^1,3 (AUTHOR) dan.lindholm@helsinki.fi, Eriksson, Ove¹ (AUTHOR) ove.eriksson@helsinki.fi

Source: Cells (2073-4409). May2022, Vol. 11 Issue 10, p1703-N.PAG. 9p.

Subject Terms: *MITOCHONDRIAL proteins, *SERINE proteinases, *TARGETED drug delivery, *CELL physiology, *BETA lactamases, *LIPID metabolism

SETBP1 induces transcription of a network of development genes by acting as an epigenetic hub

Authors: Piazza, Rocco, Magistroni, Vera, Redaelli, Sara, Mauri, Mario, Massimino, Luca, Sessa, Alessandro, Peronaci, Marco, Lalowski, Maciej, Soliymani, Rabah, Mezzatesta, Caterina, Pirola, Alessandra, Banfi, Federica, Rubio, Alicia, Rea, Delphine, Stagno, Fabio, Usala, Emilio, Martino, Bruno, Campiotti, Leonardo, Merli, Michele, Passamonti, Francesco, Onida, Francesco, Morotti, Alessandro, Pavesi, Francesca, Bregni, Marco, Broccoli, Vania, Baumann, Marc, Gambacorti-Passerini, Carlo

Source: Nature communications. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153491462.0x000001&indx=1&recIds=ETOCvdc_100153491462.0x000001

Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells

Authors: Scifo, Enzo, Szwajda, Agnieszka, Soliymani, Rabah, Pezzini, Francesco, Bianchi, Marzia, Dapkunas, Arvydas, Dębski, Janusz, Uusi-Rauva, Kristiina, Dadlez, Michał, Gingras, Anne-Claude, Tyynelä, Jaana, Simonati, Alessandro, Jalanko, Anu, Baumann, Marc H., Lalowski, Maciej

Source: In Journal of Proteomics 18 June 2015 123:42-53

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

Authors: Hosp, Fabian, Vossfeldt, Hannes, Heinig, Matthias, Vasiljevic, Djordje, Arumughan, Anup, Wyler, Emanuel, Landthaler, Markus, Hubner, Norbert, Wanker, Erich E., Lannfelt, Lars, Ingelsson, Martin, Lalowski, Maciej, Voigt, Aaron, Selbach, Matthias

Source: In Cell Reports 19 May 2015 11(7):1134-1146

Estrogenic regulation of skeletal muscle proteome: a study of premenopausal women and postmenopausal MZ cotwins discordant for hormonal therapy

Authors: Laakkonen, Eija K., Soliymani, Rabah, Karvinen, Sira, Kaprio, Jaakko, Kujala, Urho M., Baumann, Marc, Sipilä, Sarianna, Kovanen, Vuokko, Lalowski, Maciej

Source: Aging cell. 16(6):1276-1287

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128694776.0x000001&indx=1&recIds=ETOCvdc_100128694776.0x000001

Recent advances in applying mass spectrometry and systems biology to determine brain dynamics

Authors: Scifo, Enzo, Calza, Giulio, Fuhrmann, Martin, Soliymani, Rabah, Baumann, Marc, Lalowski, Maciej

Source: Expert review of proteomics. 14(6):545-559

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103559875.0x000001&indx=1&recIds=ETOCvdc_100103559875.0x000001

Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome

Authors: Đermadi, Denis, Valo, Satu, Pussila, Marjaana, Reyhani, Nima, Sarantaus, Laura, Lalowski, Maciej, Baumann, Marc, Nyström, Minna

Source: In The Journal of Nutritional Biochemistry November 2014 25(11):1196-1206

Global Analysis of S-nitrosylation Sites in the Wild Type (APP) Transgenic Mouse Brain-Clues for Synaptic Pathology

Authors: Zaręba-Kozioł, Monika ^‡, Szwajda, Agnieszka ^§, Dadlez, Michał ^‡, Wysłouch-Cieszyńska, Aleksandra ^{‡, **}, Lalowski, Maciej ^{¶, ‖, **}

Source: In Molecular & Cellular Proteomics September 2014 13(9):2288-2305

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Proteomic and functional analyses in disease models reveal CLN5 protein involvement in mitochondrial dysfunction

Authors: Doccini, Stefano, Morani, Federica, Nesti, Claudia, Pezzini, Francesco, Calza, Giulio, Soliymani, Rabah, Signore, Giovanni, Rocchiccioli, Silvia, Kanninen, Katja M., Huuskonen, Mikko T., Baumann, Marc H., Simonati, Alessandro, Lalowski, Maciej M., Santorelli, Filippo M.

Source: Cell death discovery. 6(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174645164.0x000001&indx=1&recIds=ETOCvdc_100174645164.0x000001