Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels

Authors: Bahlmann, Laura C., Xue, Chang, Chin, Allysia A., Skirzynska, Arianna, Lu, Joy, Thériault, Brigitte, Uehling, David, Yerofeyeva, Yulia, Peters, Rachel, Liu, Kela, Chen, Jianan, Martel, Anne L., Yaffe, Martin, Al-awar, Rima, Goswami, Rashmi S., Ylanko, Jarkko, Andrews, David W., Kuruvilla, John, Laister, Rob C., Shoichet, Molly S.

Source: In Biomaterials June 2023 297

Blood-based biomarkers of cancer-related cognitive impairment in non-central nervous system cancer: A scoping review

Authors: Oppegaard, Kate R., Armstrong, Terri S., Anguera, Joaquin A., Kober, Kord M., Kelly, Debra Lynch, Laister, Rob C., Saligan, Leorey N., Ayala, Ana Patricia, Kuruvilla, John, Alm, Mark W., Byker, William H., Miaskowski, Christine, Mayo, Samantha J.

Source: In Critical Reviews in Oncology / Hematology December 2022 180

An evaluation of pembrolizumab for classical Hodgkin lymphoma

Authors: Manji, Farheen, Laister, Rob C, Kuruvilla, John

Source: Expert review of hematology. 15(4):285-293

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100149665874.0x000001&indx=1&recIds=ETOCvdc_100149665874.0x000001

Coenzyme A fuels T cell anti-tumor immunity

Authors: St. Paul, Michael, Saibil, Samuel D., Han, SeongJun, Israni-Winger, Kavita, Lien, Scott C., Laister, Rob C., Sayad, Azin, Penny, Susanne, Amaria, Rodabe N., Haydu, Lauren E., Garcia-Batres, Carlos R., Kates, Meghan, Mulder, David T., Robert-Tissot, Céline, Gold, Matthew J., Tran, Charles W., Elford, Alisha R., Nguyen, Linh T., Pugh, Trevor J., Pinto, Devanand M., Wargo, Jennifer A., Ohashi, Pamela S.

Source: In Cell Metabolism 7 December 2021 33(12):2415-2427

Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment

Authors: Izreig, Said, Gariepy, Alexandra, Kaymak, Irem, Bridges, Hannah R., Donayo, Ariel O., Bridon, Gaëlle, DeCamp, Lisa M., Kitchen-Goosen, Susan M., Avizonis, Daina, Sheldon, Ryan D., Laister, Rob C., Minden, Mark D., Johnson, Nathalie A., Duchaine, Thomas F., Rudoltz, Marc S., Yoo, Sanghee, Pollak, Michael N., Williams, Kelsey S., Jones, Russell G.

Source: In Cell Reports Medicine 19 May 2020 1(2)

Biomarkers of outcome in patients undergoing CD19 CAR‐T therapy for large B cell lymphoma.

Authors: Gong, Inna Y., Tran, Daisy, Saibil, Samuel, Laister, Rob C., Kuruvilla, John

Source: HemaSphere; Aug2024, Vol. 8 Issue 8, p1-15, 15p

The SMX DNA Repair Tri-nuclease

Authors: Wyatt, Haley D.M., Laister, Rob C., Martin, Stephen R., Arrowsmith, Cheryl H., West, Stephen C.

Source: In Molecular Cell 2 March 2017 65(5):848-860

Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy

Authors: St. Paul, Michael, Saibil, Samuel D., Kates, Meghan, Han, SeongJun, Lien, Scott C., Laister, Rob C., Hezaveh, Kebria, Kloetgen, Andreas, Penny, Susanne, Guo, Tingxi, Garcia-Batres, Carlos, Smith, Logan K., Chung, Douglas C., Elford, Alisha R., Sayad, Azin, Pinto, Devanand, Mak, Tak W., Hirano, Naoto, McGaha, Tracy, Ohashi, Pamela S.

Source: In Cell Reports Medicine 19 March 2024 5(3)

Human Macrophage Invasion: Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior (Adv. Funct. Mater. 28/2021)

Authors: Bahlmann, Laura C., Baker, Alexander E. G., Xue, Chang, Liu, Sophie, Meier‐Merziger, Moritz, Karakas, Danielle, Zhu, Luke, Co, Ileana, Zhao, Spencer, Chin, Allysia, McGuigan, Alison, Kuruvilla, John, Laister, Rob C., Shoichet, Molly S.

Source: Advanced functional materials. 31(28)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123847694.0x000001&indx=1&recIds=ETOCvdc_100123847694.0x000001

Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior

Authors: Bahlmann, Laura C., Baker, Alexander E. G., Xue, Chang, Liu, Sophie, Meier‐Merziger, Moritz, Karakas, Danielle, Zhu, Luke, Co, Ileana, Zhao, Spencer, Chin, Allysia, McGuigan, Alison, Kuruvilla, John, Laister, Rob C., Shoichet, Molly S.

Source: Advanced functional materials. 31(28)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123198529.0x000001&indx=1&recIds=ETOCvdc_100123198529.0x000001

The CDK inhibitor AT7519M in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. A Phase II study of the Canadian Cancer Trials Group

Authors: Seftel, Matthew D., Kuruvilla, John, Kouroukis, Tom, Banerji, Versha, Fraser, Graeme, Crump, Michael, Kumar, Rajat, Chalchal, Haji I., Salim, Muhammad, Laister, Rob C., Crocker, Susan, Gibson, Spencer B., Toguchi, Marcia, Lyons, John F., Xu, Hao, Powers, Jean, Sederias, Joana, Seymour, Lesley, Hay, Annette E.

Source: Leukemia & lymphoma. 58(6):1358-1365

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100048552807.0x000001&indx=1&recIds=ETOCvdc_100048552807.0x000001

GNASknockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma

Authors: He, Michael Y., Tong, Kit I., Liu, Ting, Whittaker Hawkins, Ryder, Shelton, Victoria, Zeng, Yong, Bakhtiari, Mehran, Xiao, Yufeng, Zheng, Guangrong, Sakhdari, Ali, Yang, Lin, Xu, Wenxi, Brooks, David G., Laister, Rob C., He, Housheng Hansen, Kridel, Robert

Source: Leukemia; 20240101, Issue: Preprints p1-15, 15p

Analysis of the Circulating Metabolome of Patients with Cutaneous, Mucosal and Uveal Melanoma Reveals Distinct Metabolic Profiles with Implications for Response to Immunotherapy.

Authors: Vilbert, Maysa, Koch, Erica C., Rose, April A. N., Laister, Rob C., Gray, Diana, Sotov, Valentin, Penny, Susanne, Spreafico, Anna, Pinto, Devanand M., Butler, Marcus O., Saibil, Samuel D.

Source: Cancers; Jul2023, Vol. 15 Issue 14, p3708, 13p

Subject Terms: HETEROCYCLIC compounds, SKIN tumors, MELANOMA, DRUG resistance in cancer cells, LOGROLLING (Medical procedure), MUCOUS membranes, IMMUNOTHERAPY, SCIENTIFIC observation, KRUSKAL-Wallis Test, APOPTOSIS, ANTINEOPLASTIC agents, UVEAL melanoma, TREATMENT effectiveness, CANCER patients, CELLULAR signal transduction, RETROSPECTIVE studies, MANN Whitney U Test, DESCRIPTIVE statistics, IMMUNE checkpoint inhibitors, SPHINGOLIPIDS, LONGITUDINAL method, KAPLAN-Meier estimator, AMINES, RESEARCH, ANALYSIS of variance, METABOLOMICS, TRYPTOPHAN, DATA analysis software, DRUG development, OVERALL survival, PROPORTIONAL hazards models, EVALUATION

Early Steps in Oxidation-Induced SOD1 Misfolding: Implications for Non-Amyloid Protein Aggregation in Familial ALS

Authors: Mulligan, Vikram Khipple, Kerman, Aaron, Laister, Rob C., Sharda, Priya Roy, Arslan, Pharhad Eli, Chakrabartty, Avijit

Source: In Journal of Molecular Biology 24 August 2012 421(4-5):631-652

CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization

Authors: Ceccarelli, Derek F., Laister, Rob C., Mulligan, Vikram Khipple, Kean, Michelle J., Goudreault, Marilyn, Scott, Ian C. ^**, Derry, W. Brent ^**, Chakrabartty, Avijit, Gingras, Anne-Claude, Sicheri, Frank

Source: In Journal of Biological Chemistry 15 July 2011 286(28):25056-25064

Nuclear Export in Non-Hodgkin Lymphoma and Implications for Targeted XPO1 Inhibitors.

Authors: Trkulja, Kyla L., Manji, Farheen, Kuruvilla, John, Laister, Rob C.

Source: Biomolecules (2218-273X); Jan2023, Vol. 13 Issue 1, p111, 17p

Subject Terms: NON-Hodgkin's lymphoma, IMMUNOMODULATORS, MESSENGER RNA, TRANSCRIPTION factors, GENE expression, NON-coding RNA, RITUXIMAB

A Structure-based Model of the c-Myc/Bin1 Protein Interaction Shows Alternative Splicing of Bin1 and c-Myc Phosphorylation are Key Binding Determinants

Authors: Pineda-Lucena, Antonio ^†, Ho, Cynthia S.W. ^†, Mao, Daniel Y.L., Sheng, Yi, Laister, Rob C., Muhandiram, Ranjith, Lu, Ying, Seet, Bruce T., Katz, Sigal, Szyperski, Thomas, Penn, Linda Z., Arrowsmith, Cheryl H.

Source: In Journal of Molecular Biology 2005 351(1):182-194

Molecular basis of Pirh2-mediated p53 ubiquitylation.

Authors: Sheng, Yi^1,2, Laister, Rob C.¹, Lemak, Alexander¹, Wu, Bin¹, Tai, Elizabeth¹, Duan, Shili¹, Lukin, Jonathan¹, Sunnerhagen, Maria³, Srisailam, Sampath¹, Karra, Murthy¹, Benchimol, Sam², Arrowsmith, Cheryl H.¹ carrow@uhnres.utoronto.ca

Source: Nature Structural & Molecular Biology. Dec2008, Vol. 15 Issue 12, p1334-1342. 9p. 6 Diagrams, 1 Chart, 1 Graph.

Subject Terms: *TUMOR suppressor proteins, *NUCLEAR magnetic resonance spectroscopy, *P53 protein, *UBIQUITIN, *LIGASES

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Obinutuzumab Plus Gemcitabine, Dexamethasone and Cisplatin (O-GDP) As Salvage Chemotherapy Prior to Autologous Stem Cell Transplant in Aggressive B Cell Lymphoma

Authors: Jain, Michael D., Prica, Anca, Morin, Ryan D., Kukreti, Vishal, Kridel, Robert, Laister, Rob C. ^*, Meng, Li ^*, Rushton, Christopher ^*, Alcaide, Miguel ^*, Goswami, Rashmi S. ^*, Delabie, Jan ^*, Weiss, Jessica ^*, Panzarella, Tony ^*, Crump, Michael ^*, Scott, David W., Kuruvilla, John

Source: In Blood 13 November 2019 134 Supplement 1:2027-2027