Efficacy of subsequent therapies in patients with advanced ovarian cancer who relapse after first-line olaparib maintenance: results of the PAOLA-1/ENGOT-ov25 trial

Authors: Bogner, Gerhard, Marth, Christian, Petru, Edgar, Reinthaller, Alexander, Schauer, Christian, Sevelda, Paul, D’Hondt, Lionel, Vergote, Ignace, Vuylsteke, Peter, Hietanen, Sakari, Lindahl, Gabriel, Mäenpää, Johanna, Nøttrup, Trine Jakobi, Puistola, Ulla, Abadie-Lacourtoisie, Sophie, Alexandre, Jérôme, Berton-Rigaud, Dominique, Boissier, Emilie, Bourgeois, Hugues, Chevalier-Place, Annick, Combe, Pierre, Costan, Cristina, Dauba, Jérôme, De Cock, Laure, Desauw, Christophe, Despax, Raymond, Dohollou, Nadine, Dubot, Coraline, Fabbro, Michel, Favier, Laure, Floquet, Anne, Follana, Philippe, Tixidre, Claire Garnier, Garnier, Georges, Gladieff, Laurence, Grenier, Julien, Guillemet, Cécile, Hardy-Bessard, Anne-Claire, Joly, Florence, Kalbacher, Elsa, Kaminsky, Marie-Christine, Kurtz, Jean-Emmanuel, Largillier, Rémy, Lefeuvre-Plesse, Claudia, Lesoin, Anne, Levache, Charles Briac, L’Haridon, Tifenn, Lortholary, Alain, Lotz, Jean-Pierre, Medioni, Jacques, Meunier, Jérôme, Mousseau, Mirerille, Mouret-Reynier, Marie-Ange, Pautier, Patricia, Petit, Thierry, Provansal, Magali, Pujade-Lauraine, Eric, Raban, Nadia, Ray-Coquard, Isabelle, Rodrigues, Manuel, Selle, Frédéric, Sverdlin, Robert, Tazi, Youssef, You, Benoît, Aktas, Bahriye, Olaf Bauerschlag, Dirk, Beck, Thomas, Belau, Antje, Bronger, Holger, Buchholz, Stefan, Buderath, Paul, Burges, Alexander, Canzler, Ulrich, de Gregorio, Nikolaus, Denschlag, Dominik, Dieterich, Max, Eichbaum, Michael, El-Balat, Ahmed, Emons, Günter, Fasching, Peter, Feisel-Schwickardi, Gabriele, Frank, Matthias, Friedrich, Michael, Grischke, Eva-Maria, Gropp-Meier, Martina, Hanker, Lars, Hannig, Carla, Harter, Philipp, Hasenburg, Annette, Hellriegel, Martin, Herwig, Uwe, Heubner, Martin, Hulde, Joachim, Jackisch, Christian, Kögel, Matthias, Krieger, Peter, Kühn, Thorsten, Liebrich, Clemens, Lück, HansJoachim, Mallmann, Peter, Marmé, Frederik, Meier, Werner, Möbus, Voker, Mohamed, Omar Farag, Nestle-Krämling, Carolin, Neunhöffer, Tanja, Oskay-Özcelik, Gülten, Park-Simon, Tjoung-Won, Rautenberg, Beate, Rein, Daniel, Ruhwedel, Wencke, Runnebaum, Ingo, Sagasser, Jacqueline, Schmalfeldt, Barbara, Schneeweiss, Andreas, Schnelzer, Andreas, Scholz, Heinz, Sehouli, Jalid, Sperfeld, Antje, Steckkönig, Annette, Strauß, Hans-Georg, Tomé, Oliver, Treustedt, Jörn, Voß, Hermann, Wischnik, Arthur, Witteler, Ralf, Wöckel, Achim, Woeltjen, Hans-Heinrich, Zorr, Andreas, Bologna, Alessandra, Colombo, Nicoletta, Tognon, Germana, Cinieri, Saverio, Lorusso, Domenica, Mosconi, Anna Maria, Pignata, Sandro, Savarese, Antonella, Scambia, Giovanni, Sorio, Roberto, Zamagni, Claudio, Fujiwara, Keiichi, Fujiwara, Hiroyuki, Kobayashi, Hiroaki, Matsumoto, Takashi, Nagao, Shoji, Satoh, Toyomi, Yonemori, Kan, Yoshida, Hiroyuki, Bratos, Raquel, Caballero, Cristina, Garica, Yolanda, González-Martín, Antonio, Guerra-Alía, Eva Maria, Hernando, Susana, Herrero, Ana, Lainez, Nuria, Manso, Luis, Martin, Cristina, Murata, Eleonor, Ortega, Eugenia, Palacio, Isabel, Poveda, Andres, Romero, Ignacio, Rubio-Pérez, María Jesús, Harter, P. ^{1, 2, 3, †}, Marth, C. ^{4, 5, †}, Mouret-Reynier, M.-A. ^{6, 7}, Cropet, C. ⁸, Lorusso, D. ^{9, 10, 11}, Guerra-Alía, E.M. ^{12, 13}, Matsumoto, T. ^{14, 15}, Vergote, I. ^{16, 17}, Colombo, N. ^{18, 19}, Mäenpää, J. ^{20, 21}, Lebreton, C. ^{7, 22}, de Gregorio, N. ^{3, 23}, Mosconi, A.M. ^{11, 24}, Rubio-Pérez, M.J. ^{13, 25}, Bourgeois, H. ^{7, 26}, Fasching, P.A. ^{3, 27}, Cecere, S.C. ^{11, 28}, Hardy-Bessard, A.-C. ^{7, 29}, Denschlag, D. ^{3, 30}, de Percin, S. ^{7, 31}, Hanker, L. ^{3, 32, 33}, Favier, L. ^{7, 34}, Bauerschlag, D. ^{3, 35, ‡}, Desauw, C. ^{7, 36}, Hillemanns, P. ^{3, 37}, Largillier, R. ^{7, 38}, Sehouli, J. ^{3, 39}, Grenier, J. ^{7, 40}, Pujade-Lauraine, E. ^{7, 41}, Ray-Coquard, I. ^{7, 42, ∗}

Source: In Annals of Oncology February 2025 36(2):185-196

Adverse events in the placebo arm of SOLO2/ENGOT-Ov21 maintenance trial of olaparib in recurrent ovarian cancer

Authors: Francis, Katherine Elizabeth ^{a, b, ⁎}, Simon, Sandy ^a, Gebski, Val ^a, Joly, Florence ^{c, d}, Ledermann, Jonathan A. ^e, Penson, Richard T. ^f, Oza, Amit M. ^g, Korach, Jacob ^h, Lainez, Nuria ⁱ, Cecere, Sabrina Chiara ^j, Tasca, Giulia ^k, Gropp-Meier, Martina ^{l, m}, Fujiwara, Keiichi ⁿ, Lowe, Elizabeth S. ^o, Friedlander, Michael ^{p, q}, Pujade-Lauraine, Eric ^r, Lee, Chee Khoon ^{a, s}

Source: In Gynecologic Oncology January 2025 192:50-55

Phase II clinical trial assessing the efficacy of enzalutamide in advanced non-resectable granulosa cell ovarian tumors: The GREKO III study (GETHI2016–01)

Authors: García-Donas, Jesus, Redondo, Andres, Santaballa, Ana, Garrigos, Laia, Rubio, Mª. Jesus, Lainez, Nuria, González, María Iglesias, Cueva, Juan Fernando, Barquin, Arantzazu, Grazioso, Tatiana P., Hurtado, Alicia, Sevillano, Elena, Grande, Enrique, Rodriguez-Moreno, Juan Francisco, Navarro, Paloma

Source: In Gynecologic Oncology December 2024 191:233-239

Prospective Assessment of Bone Metabolism Biomarkers and Survival in Metastatic Castration-resistant Prostate Cancer Patients Treated with Radium-223: The PRORADIUM Study

Authors: Romero-Laorden, Nuria, Lorente, David, de Velasco, Guillermo, Lozano, Rebeca, Herrera, Bernardo, Puente, Javier, López, Pedro P., Medina, Ana, Almagro, Elena, Gonzalez-Billalabeitia, Enrique, Villla-Guzman, Jose Carlos, González-del-Alba, Aránzazu, Borrega, Pablo, Laínez, Nuria, Fernández-Freire, Ana, Hernández, Amaia, Rodriguez-Vida, Alejo, Chirivella, Isabel, Fernandez-Parra, Eva, López-Campos, Fernando, Isabel Pacheco, Maria, Morales-Barrera, Rafael, Fernández, Ovidio, Villatoro, Rosa, Luque, Raquel, Hernando, Susana, Castellano, Daniel C., Castro, Elena, Olmos, David

Source: In European Urology Oncology June 2024 7(3):447-455

Clinical Factors Associated With Long-Term Benefit in Patients With Metastatic Renal Cell Carcinoma Treated With Axitinib: Real-World AXILONG Study

Authors: Pinto, Álvaro, Reig, Oscar, Iglesias, Clara, Gallardo, Enrique, García-del Muro, Xavier, Alonso, Teresa, Anguera, Georgia, Suárez, Cristina, Muñoz-Langa, José, Villalobos-León, Laura, Rodríguez-Sánchez, Ángel, Lainez, Nuria, Martínez-Ortega, Esther, Campayo, Marc, Velastegui, Alejandro, Rodriguez-Vida, Alejo, Villa-Guzmán, José C., Méndez-Vidal, Maria J., Rubio, Gustavo, García, Iciar, Capdevila, Laia, Lambea, Julio, Vázquez, Sergio, Fernández, Ovidio, Hernando-Polo, Susana, Cerezo, Sara, Santander, Carmen, García-Marrero, Rosa, Zambrana, Francisco, González-del Alba, Aranzazu, Lazaro-Quintela, Martin, Castellano, Daniel, Chirivella, Isabel, Anido, Urbano, Viana, Antonio, García, Arancha, Sotelo, Miguel, Arévalo, María Garrido, García-Donas, Jesús, Hernández, Carolina, Bolós, M. Victoria, Llinares, Julia, Climent, Miguel A.

Source: Clinical genitourinary cancer. 20(1):25-34

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167674826.0x000001&indx=1&recIds=ETOCvdc_100167674826.0x000001

Phase 2 study of perioperative sacituzumab govitecan in combination with zimberelimab and domvanalimab for patients with muscle invasive bladder cancer ineligible or who refuse cisplatin-based chemotherapy: The PRISMA-1 study.

Authors: Duran, Ignacio, Climent Duran, Miguel A., García Carbonero, Iciar, Villares, Angela, Sánchez-Escribano, Ricardo, Calleja, Jesus, Sagastibelza, Naiara, Villafruela, Ainara, Galante, Isabel, Dominguez, Jose Luis, Font Pous, Albert, Servian, Pol, Lainez, Nuria, Grasa, Vicente, Anido, Urbano, Cimadevila, Anton, Dominguez, Mario, Garcia del Muro, Xavier, Buisan, Oscar, Puente, Javier

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, pTPS884-TPS884, 242p

Recent therapeutic advances in urothelial carcinoma: A paradigm shift in disease management

Authors: Bellmunt, Joaquim, Valderrama, Begoña P., Puente, Javier, Grande, Enrique, Bolós, M. Victoria, Lainez, Nuria, Vázquez, Sergio, Maroto, Pablo, Climent, Miguel Ángel, Garcia del Muro, Xavier, Arranz, José Ángel, Durán, Ignacio

Source: In Critical Reviews in Oncology / Hematology June 2022 174

Prevalence of pathogenic germline variants in patients with metastatic renal cell carcinoma

Authors: Santos, María, Lanillos, Javier, Roldan-Romero, Juan María, Caleiras, Eduardo, Montero-Conde, Cristina, Cascón, Alberto, Climent, Miguel Angel, Anguera, Georgia, Hernando, Susana, Laínez, Nuria, Robledo, Mercedes, Robles, Luis, de Velasco, Guillermo, García-Donas, Jesús, Rodriguez-Antona, Cristina

Source: In Genetics in Medicine April 2021 23(4):698-704

Association Between Second Progression-free Survival (PFS2) and Overall Survival in Metastatic Castration-resistant Prostate Cancer

Authors: Lorente, David, Castro, Elena, Lozano, Rebeca, Puente, Javier, Romero-Laorden, Nuria, Rodríguez-Vida, Alejo, Lainez, Nuria, Villatoro, Rosa, Llácer, Casilda, Cattrini, Carlo, Hernández, Amaia, Domenech, Montserrat, Zambrana, Francisco, Almagro, Elena, Luque, Raquel, Martinez, Esther, López-Campos, Fernando, Gonzalez, Belen, Méndez-Vidal, Maria Jose, Medina, Ana, Piulats, Josep Maria, Olmos, David

Source: European urology. 77(6):763-766

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114375793.0x000001&indx=1&recIds=ETOCvdc_100114375793.0x000001

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma

Authors: Roldan‐Romero, Juan M., Beuselinck, Benoit, Santos, María, Rodriguez‐Moreno, Juan F., Lanillos, Javier, Calsina, Bruna, Gutierrez, Ana, Tang, Karin, Lainez, Nuria, Puente, Javier, Castellano, Daniel, Esteban, Emilio, Climent, Miguel A., Arranz, Jose A., Albersen, Maarten, Oudard, Stephane, Couchy, Gabrielle, Caleiras, Eduardo, Montero‐Conde, Cristina, Cascón, Alberto, Robledo, Mercedes, Rodríguez‐Antona, Cristina, García‐Donas, Jesús

Source: International journal of cancer. 146(5):1435-1444

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099717977.0x000001&indx=1&recIds=ETOCvdc_100099717977.0x000001

PRO-WAVE1: Monitoring patient reported outcomes (PROs) in prostate cancer through Wave Health, a novel ePRO health platform.

Authors: Lashey, Matthew David, Linares Espinos, Estefania, Basterretxea, Laura, Gurruchaga, Ibon, Gomez Mediavilla, Borja, Esteban, Brigida, Cacho, Diego, Congregado, Belen, Rivero Belenchon, Ines, Hernandez, Amaia, Sancho, Gemma, Lainez, Nuria, Buchser, David, Sanguedolce, Francesco, Duran, Ignacio

Source: Journal of Clinical Oncology; 2024 Supplement, Vol. 42, p192-192, 10p

Image-guided brachytherapy in cervical cancer: Experience in the Complejo Hospitalario de Navarra

Authors: Villafranca, Elena, Navarrete, Paola, Sola, Amaya, Muruzabal, Juan Carlos, Aguirre, Sara, Ostiz, Santiago, Sanchez, Carmen, Guarch, Rosa, Lainez, Nuria, Barrado, Marta

Source: In Reports of Practical Oncology & Radiotherapy November-December 2018 23(6):510-516

Results of the FLAC European Database of Metastatic Castration-Resistant Prostate Cancer Patients Treated With Docetaxel, Cabazitaxel, and Androgen Receptor–Targeted Agents

Authors: Angelergues, Antoine, Efstathiou, Eleni, Gyftaki, Revekka, Wysocki, Piotr Jan, Lainez, Nuria, Gonzalez, Iria, Castellano, Daniel E., Ozguroglu, Mustafa, Carbonero, Iciar Garcia, Flechon, Aude, Borrega, Pablo, Guillot, Aline, Balea, Begona Campos, Le Moulec, Sylvestre, Esteban, Emilio, Munarriz, Javier, Rubio, Gustavo, Birtle, Alison J., Delanoy, Nicolas, Bellmunt, Joaquim, Oudard, Stéphane

Source: In Clinical Genitourinary Cancer August 2018 16(4):e777-e784

Maintenance therapy with vinflunine plus best supportive care versus best supportive care alone in patients with advanced urothelial carcinoma with a response after first-line chemotherapy (MAJA; SOGUG 2011/02): a multicentre, randomised, controlled, open-label, phase 2 trial

Authors: García-Donas, Jesus, Font, Albert, Pérez-Valderrama, Begoña, Virizuela, José Antonio, Climent, Miquel Ángel, Hernando-Polo, Susana, Arranz, José Ángel, del Mar Llorente, Maria, Lainez, Nuria, Villa-Guzmán, José Carlos, Mellado, Begoña, del Alba, Aránzazu González, Castellano, Daniel, Gallardo, Enrique, Anido, Urbano, del Muro, Xavier García, Domènech, Montserrat, Puente, Javier, Morales-Barrera, Rafael, Pérez-Gracia, Jose Luis, Bellmunt, Joaquim

Source: In The Lancet Oncology May 2017 18(5):672-681

Recent advances in genitourinary tumors: A review focused on biology and systemic treatment

Authors: González del Alba, Aránzazu, Arranz, José Ángel, Puente, Javier, Méndez-Vidal, María José, Gallardo, Enrique, Grande, Enrique, Pérez-Valderrama, Begoña, González-Billalabeitia, Enrique, Lázaro-Quintela, Martín, Pinto, Álvaro, Lainez, Nuria, Piulats, Josep M., Esteban, Emilio, Maroto Rey, José Pablo, García, Jorge A., Suárez, Cristina

Source: In Critical Reviews in Oncology / Hematology May 2017 113:171-190

PRO-WAVE1: Monitoring patient reported outcomes (PROs) in prostate cancer through Wave Health, a novel ePRO health platform.

Authors: Cacho, Diego, Congregado, Belen, Rivero Belenchon, Ines, Linares Espinos, Estefania, Basterretxea, Laura, Sancho, Gemma, Lainez, Nuria, Buchser, David, Sanguedolce, Francesco, Gurruchaga, Ibon, Gomez Mediavilla, Borja, Esteban, Brigida, Hernandez, Amaia, Lashey, Matthew, Duran, Ignacio

Source: Journal of Clinical Oncology; 2024 Supplement 4, Vol. 42, p114-114, 235p

SNPs associated with activity and toxicity of cabazitaxel in patients with advanced urothelial cell carcinoma

Authors: Duran, Ignacio, Hagen, Carlos, Arranz, José Ángel, Apellaniz-Ruiz, María, Pérez-Valderrama, Begoña, Sala, Nuria, Lainez, Nuria, García-Del Muro, Xavier, Noguerón, Esther, Climent, Miguel Ángel, Maroto, Pablo, Font, Albert, García-Donas, Jesús, Gallardo, Enrique, López-Criado, Pilar, González Del Alba, Aránzazu, Sáez, María Isabel, Vázquez, Sergio, Luque, Raquel, Rodríguez-Antona, Cristina

Source: Pharmacogenomics. 17(5):463-471

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132328432.0x000001&indx=1&recIds=ETOCvdc_100132328432.0x000001

Open-label phase II clinical trial of ketoconazole as CYP17 inhibitor in metastatic or advanced non-resectable granulosa cell ovarian tumors: the GREKO (GRanulosa Et KetOconazole) trial, GETHI 2011-03.

Authors: Garcia-Donas, Jesus, Hurtado, Alicia, Garrigos, Laia, Santaballa, Ana, Redondo, Andres, Vidal, Laura, Lainez, Nuria, Guerra, Eva, Rodriguez, Victor, Cueva, Juan, Bover, Isabel, Palacio, Isabel, Rubio, Maria Jesus, Prieto, Mario, Lopez-Guerrero, Jose Antonio, Rodriguez-Moreno, Juan Francisco, Garcia-Casado, Zaida, Garcia-Martinez, Elena, Taus, Alvaro, de Castro, Ignacio Pérez

Source: Clinical & Translational Oncology; Jul2023, Vol. 25 Issue 7, p2090-2098, 9p

Comprehensive molecular characterization of muscle-invasive bladder cancer (MIBC) treated with durvalumab plus olaparib in the neoadjuvant setting: Neodurvarib trial.

Authors: Rodriguez-Moreno, Juan Francisco, Ruiz-Llorente, Sergio, De Velasco, Guillermo, Alvarez-Fernandez, Carlos, Collado Martín, Ricardo, Fernandez, Ricardo, Vazquez-Estevez, Sergio, Virizuela, Juan Antonio, Gajate, Pablo, Font, Albert, Lainez, Nuria, Barquin, Arantzazu, Beltran, Luis, Rodriguez-Antona, Cristina, Berraondo, Pedro, García-Donas, Jesús

Source: Journal of clinical oncology. 40(6 suppl):546-546

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155645493.0x000001&indx=1&recIds=ETOCvdc_100155645493.0x000001

Impact on clinical practice of the implementation of guidelines for the toxicity management of targeted therapies in kidney cancer. The protect-2 study.

Authors: Lainez, Nuria¹, García-Donas, Jesús², Esteban, Emilio³, Puente, Javier⁴, Sáez, M. Isabel⁴, Gallardo, Enrique⁵, Pinto-Marín, Álvaro⁶, Vázquez-Estévez, Sergio⁷, León, Luis⁸, García-Carbonero, Icíar⁹, Suárez-Rodríguez, Cristina¹⁰, Molins, Carmen¹⁰, Climent-Duran, Miguel A.¹¹, Lázaro-Quintela, Martín¹², del Alba, Aranzazu González¹³, Méndez-Vidal, María José¹⁴, Chirivella, Isabel¹⁴, Afonso, Francisco J.¹⁵, López-Brea, Marta¹⁶, Sala-González, Nuria¹⁶

Source: BMC Cancer. 2/22/2016, Vol. 16, p1-10. 10p. 1 Diagram, 5 Charts, 1 Graph.

Subject Terms: *RENAL cancer treatment, *CANCER treatment, *RENAL cell carcinoma, *ADVERSE health care events, *HYPERTENSION, *DATA analysis, *ONCOLOGY research, *ANTINEOPLASTIC agents, *DRUG therapy, *KIDNEY tumors, *MEDICAL protocols, *METASTASIS

Geographic Terms: SPAIN