Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1

Authors: Guennadi Kozlov, Jianning Jiang, Tyler Rutherford, Anne M. Noronha, Christopher J. Wilds, Kalle Gehring

Source: RNA Biology, Vol 21, Iss 1, Pp 764-773 (2024)

Subject Terms: LaM, La motif, LARP, La-related protein, LARP1, La-related protein 1, poly(a) tail, guanylation, phosphorothioate, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1547-6286; https://doaj.org/toc/1555-8584

Access URL: https://doaj.org/article/6b6546ccc14b42b59f428ad7279add2a

LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs

Authors: Sungki Hong, Mallory A Freeberg, Ting Han, Avani Kamath, Yao Yao, Tomoko Fukuda, Tsukasa Suzuki, John K Kim, Ken Inoki

Source: eLife, Vol 6 (2017)

Subject Terms: La-related protein 1, mTORC1, translation, Akt, ribosome biogenesis, S6K1, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/25237; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/1be33cf3c8b74fcaae03444cd7d5f0d1

La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs

Authors: Roni M Lahr, Bruno D Fonseca, Gabrielle E Ciotti, Hiba A Al-Ashtal, Jian-Jun Jia, Marius R Niklaus, Sarah P Blagden, Tommy Alain, Andrea J Berman

Source: eLife, Vol 6 (2017)

Subject Terms: TOP mRNAs, 5' cap, La-related protein 1, eIF4E, RNA binding protein, X-ray crystallography, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/24146; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/52cd9152533a46c6bc990f5a688837bf

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