Evaluation of antitumor activity of survivin short interfering RNA delivered by lipid nanoparticles in colon cancer in vitro and in vivo.

Authors: TIANYOU WANG, ZIQIN LIU, ZHAOXIA ZHANG, SUOQIN TANG, MEI YUE, SHUNQIAO FENG, MENGZE HU, LITIAN XUAN, YANFEI CHEN

Source: Oncology Letters; Aug2017, Vol. 14 Issue 2, p2001-2008, 8p

Subject Terms: ANTINEOPLASTIC agents, RNA, GENETIC overexpression, APOPTOSIS, SMALL interfering RNA, THERAPEUTICS

Small interfering RNA targeting of the survivin gene inhibits human tumor cell growth in vitro.

Authors: ZHAOXIA ZHANG, TIANYOU WANG, ZIQIN LIU, SUOQIN TANG, MEI YUE, SHUNQIAO FENG, MENGZE HU, LITIAN XUAN, YANFEI CHEN

Source: Experimental & Therapeutic Medicine; Jul2017, Vol. 14 Issue 1, p35-42, 8p

Subject Terms: SMALL interfering RNA, TUMORS, CELL proliferation, CELL division, PROPIDIUM iodide

Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study.

Authors: ZIQIN LIU, TIANYOU WANG, ZHAOXIA ZHANG, SUOQIN TANG, SHUNQIAO FENG, MEI YUE, MENGZE HU, LITIAN XUAN, YANFEI CHEN

Source: Oncology Letters; Apr2017, Vol. 13 Issue 4, p2723-2730, 8p

Subject Terms: LIVER cancer, DOWNREGULATION, SMALL interfering RNA, MAJOR histocompatibility complex, CANCER cell proliferation, PROMOTERS (Genetics), SURVIVIN (Protein), GENETICS