A phase 3 study (PATHWAY) of palbociclib plus tamoxifen in patients with HR-positive/HER2-negative advanced breast cancer

Authors: Emi Noguchi, Takashi Yamanaka, Hirofumi Mukai, Naohito Yamamoto, Chi-Feng Chung, Yen-Shen Lu, Dwan-Ying Chang, Joohyuk Sohn, Gun Min Kim, Kyung-Hun Lee, Soo-Chin Lee, Tsutomu Iwasa, Hiroji Iwata, Kenichi Watanabe, Kyung Hae Jung, Yuko Tanabe, Seok Yun Kang, Hiroyuki Yasojima, Kenjiro Aogi, Eriko Tokunaga, Sung Hoon Sim, Yoon Sim Yap, Koji Matsumoto, Ling-Ming Tseng, Yoshiko Umeyama, Kazuki Sudo, Yuki Kojima, Tomomi Hata, Aya Kuchiba, Taro Shibata, Kenichi Nakamura, Yasuhiro Fujiwara, Kenji Tamura, Kan Yonemori

Source: npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/3cba658e7441401e9b9e50ad16a29171

Differential effects of desvenlafaxine on hot flashes in women with breast cancer taking tamoxifen: a randomized controlled trial

Authors: Yongjoo Kim, Chan-Woo Yeom, Hyun Jeong Lee, Jeong-Hyun Kim, Kwang-Min Lee, Tae-Yong Kim, Han-Byoel Lee, Hoon Kim, Seock-Ah Im, Kyung-Hun Lee, Miso Kim, Wonsik Han, Hyeong-Gon Moon, David Spiegel, Bong-Jin Hahm, Kyung-Lak Son

Source: npj Breast Cancer, Vol 10, Iss 1, Pp 1-8 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/01f6553895bd47baae9c2e4166efdbe0

Locoregional recurrence after neoadjuvant versus adjuvant chemotherapy based on tumor subtypes in patients with early-stage breast cancer: A multi-institutional retrospective cohort study

Authors: Jong-Ho Cheun, Youngji Kwak, Eunhye Kang, Ji-Jung Jung, Hong-Kyu Kim, Han-Byoel Lee, Kyung-Hun Lee, Hyeong-Gon Moon, Ki-Tae Hwang, Yeon Hee Park, Jeong Eon Lee, Wonshik Han

Source: Breast, Vol 78, Iss , Pp 103828- (2024)

Subject Terms: Adjuvant chemotherapy, Breast cancer, Breast cancer subtypes, Breast conserving, Locoregional recurrence, Neoadjuvant chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0960977624001590; https://doaj.org/toc/1532-3080

Access URL: https://doaj.org/article/69e72bca1dc84536b9d19caab0c3937b

Comparison of atezolizumab plus bevacizumab and lenvatinib for hepatocellular carcinoma with portal vein tumor thrombosis

Authors: Jeayeon Park, Yun Bin Lee, Yunmi Ko, Youngsu Park, Hyunjae Shin, Moon Haeng Hur, Min Kyung Park, Dae-Won Lee, Eun Ju Cho, Kyung-Hun Lee, Jeong-Hoon Lee, Su Jong Yu, Tae-Yong Kim, Yoon Jun Kim, Tae-You Kim, Jung-Hwan Yoon

Source: Journal of Liver Cancer, Vol 24, Iss 1, Pp 81-91 (2024)

Subject Terms: liver neoplasms, immunotherapy, immune checkpoint inhibitors, pd-l1, survival, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.e-jlc.org/upload/pdf/jlc-2023-12-25.pdf; https://doaj.org/toc/2288-8128; https://doaj.org/toc/2383-5001

Access URL: https://doaj.org/article/0fba6f18253441e3be10280165c026e9

HER2 amplification level by in situ hybridization predicts survival outcome in advanced HER2-positive breast cancer treated with pertuzumab, trastuzumab, and docetaxel regardless of HER2 IHC results

Authors: Jeongmin Seo, Jiwon Koh, Dae-Won Lee, Jinyong Kim, Han Suk Ryu, Kyung-Hun Lee, Tae-Yong Kim, Seock-Ah Im

Source: Breast Cancer Research, Vol 25, Iss 1, Pp 1-10 (2023)

Subject Terms: HER2 positive breast cancer, HER2/CEP17 ratio, HER2 copy number, HER2 in situ hybridization, Dual HER2 blockade, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1465-542X

Access URL: https://doaj.org/article/3baff563765d491e86fc3d30af39cc2a

An Antibody‐CRISPR/Cas Conjugate Platform for Target‐Specific Delivery and Gene Editing in Cancer

Authors: Seungju Yang, San Hae Im, Ju Yeon Chung, Juhee Lee, Kyung‐Hun Lee, Yoo Kyung Kang, Hyun Jung Chung

Source: Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)

Subject Terms: antibody conjugation, cancer therapy, CRISPR/Cas, in vivo gene editing, specific delivery, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/e491e54803a94d9ab7ae1524d1bc8e43

A phase Ib/II trial of capmatinib plus spartalizumab vs. spartalizumab alone in patients with pretreated hepatocellular carcinoma

Authors: Armando Santoro, Eric Assenat, Thomas Yau, Jean-Pierre Delord, Michela Maur, Jennifer Knox, Stephane Cattan, Kyung-Hun Lee, Gianluca Del Conte, Christoph Springfeld, Elisa Leo, Alexandros Xyrafas, Lauren Fairchild, Feby Mardjuadi, Stephen L. Chan

Source: JHEP Reports, Vol 6, Iss 4, Pp 101021- (2024)

Subject Terms: Capmatinib, Spartalizumab, Hepatocellular carcinoma, MET, anti-programmed death-ligand 1, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000223; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/9e42ee62344d4ac28b99c8e6f48601dc

Longitudinal multi-omics study of palbociclib resistance in HR-positive/HER2-negative metastatic breast cancer

Authors: Yeon Hee Park, Seock-Ah Im, Kyunghee Park, Ji Wen, Kyung-Hun Lee, Yoon-La Choi, Won-Chul Lee, Ahrum Min, Vinicius Bonato, Seri Park, Sripad Ram, Dae-Won Lee, Ji-Yeon Kim, Su Kyeong Lee, Won-Woo Lee, Jisook Lee, Miso Kim, Hyun Seon Kim, Scott L. Weinrich, Han Suk Ryu, Tae Yong Kim, Stephen Dann, Yu-Jin Kim, Diane R. Fernandez, Jiwon Koh, Shuoguo Wang, Song Yi Park, Shibing Deng, Eric Powell, Rupesh Kanchi Ravi, Jadwiga Bienkowska, Paul A. Rejto, Woong-Yang Park, Zhengyan Kan

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-18 (2023)

Subject Terms: Advanced breast cancer, Drug resistance, Genomic profile, Gene expression profiling, Palbociclib, Homologous recombination repair deficiengy (HRD), Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/e43bea5e36154033b3975c0ba6d40d38

Mutations of TP53 and genes related to homologous recombination repair in breast cancer with germline BRCA1/2 mutations

Authors: Jinyong Kim, Kyeonghun Jeong, Hyeji Jun, Kwangsoo Kim, Jeong Mo Bae, Myung Geun Song, Hanbaek Yi, Songyi Park, Go-un Woo, Dae-Won Lee, Tae-Yong Kim, Kyung-Hun Lee, Seock-Ah Im

Source: Human Genomics, Vol 17, Iss 1, Pp 1-10 (2023)

Subject Terms: BRCA, P53, Breast cancer, NGS, Signature 3, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1479-7364

Access URL: https://doaj.org/article/97b9dd8354224e9d95a8194d50a2dc88

Epigenetic regulation of Neuregulin 1 promotes breast cancer progression associated to hyperglycemia

Authors: Changhu Lee, Min Kim, Chanho Park, Woobeen Jo, Jeong Kon Seo, Sahee Kim, Jiyoung Oh, Chu-Sook Kim, Han Suk Ryu, Kyung-Hun Lee, Jiyoung Park

Source: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/70307856217b44f6a9332ad61e67b385

Influence of the surface flaws in oil-tempered wires on the fatigue life of automotive engine valve springs

Authors: Dae-Cheol Ko, Nam-Sik Ahn, Kyung-Hun Lee

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-22 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c458238af3df4af8bd2d413fbe79f595

A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors

Authors: Stephen L. Chan, Martin Schuler, Yoon-Koo Kang, Chia-Jui Yen, Julien Edeline, Su Pin Choo, Chia-Chi Lin, Takuji Okusaka, Karl-Heinz Weiss, Teresa Macarulla, Stéphane Cattan, Jean-Frederic Blanc, Kyung-Hun Lee, Michela Maur, Shubham Pant, Masatoshi Kudo, Eric Assenat, Andrew X. Zhu, Thomas Yau, Ho Yeong Lim, Jordi Bruix, Andreas Geier, Carmen Guillén-Ponce, Angelica Fasolo, Richard S. Finn, Jia Fan, Arndt Vogel, Shukui Qin, Markus Riester, Vasiliki Katsanou, Monica Chaudhari, Tomoyuki Kakizume, Yi Gu, Diana Graus Porta, Andrea Myers, Jean-Pierre Delord

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)

Subject Terms: Hepatocellular carcinoma, FGFR4, PD-1, PD-L1, Immune checkpoint inhibitors, Phase 1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/1a80d93b46254b83bfdf5d4c0de1a368

HER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis

Authors: Ryan Shea Ying Cong Tan, Whee Sze Ong, Kyung-Hun Lee, Abner Herbert Lim, Seri Park, Yeon Hee Park, Ching-Hung Lin, Yen-Shen Lu, Makiko Ono, Takayuki Ueno, Yoichi Naito, Tatsuya Onishi, Geok-Hoon Lim, Su-Ming Tan, Han-Byoel Lee, Han Suk Ryu, Wonshik Han, Veronique Kiak Mien Tan, Fuh-Yong Wong, Seock-Ah Im, Puay Hoon Tan, Jason Yongsheng Chan, Yoon-Sim Yap

Source: BMC Medicine, Vol 20, Iss 1, Pp 1-15 (2022)

Subject Terms: HER2-low breast cancer, ERBB2 neutral, Prognosis, TCGA, METABRIC, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/5bcb88b9c97b4e58a2441f664f3d4ca5

The impact of race and ethnicity in breast cancer—disparities and implications for precision oncology

Authors: Kelly A. Hirko, Gabrielle Rocque, Erica Reasor, Ammanuel Taye, Alex Daly, Ramsey I. Cutress, Ellen R. Copson, Dae-Won Lee, Kyung-Hun Lee, Seock-Ah Im, Yeon Hee Park

Source: BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)

Subject Terms: Breast cancer, Race, Ethnicity, Disparities, Clinical outcomes, Socioeconomic status, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/6438f34bb2234fe6997a646ee7c16fc8

Knowledge, attitudes, and behaviors toward fertility preservation in patients with breast cancer: A cross-sectional survey of physicians

Authors: Soo Yeon Baek, Kyung-Hun Lee, Sung-Bae Kim, Henry Gomez, Tatiana Vidaurre, Yeon Hee Park, Hee Kyung Ahn, Yoo Seok Kim, In Hae Park, Sung Gwe Ahn, Jeeyeon Lee, Jae Ho Jeong, Seonok Kim, Hee Jeong Kim

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: breast cancer, young age, fertility preservation, consultation and referral, survivorship, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1109694/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/a4574e6e620c404ab5bf0cfd6e0702c6

Integrated Design of Hydraulic Coupling Bolts for Large Shaft Systems

Authors: Sung-Cheol Park, In-Kyu Lee, Sang-Kon Lee, Kyung-Hun Lee

Source: Applied Sciences, Vol 14, Iss 1, p 130 (2023)

Subject Terms: hydraulic coupling bolt, integrated design, finite element analysis, structural integrity, operational experiments, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/14/1/130; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/b296e8fa8f644099b57c50e3220126f9

Prospective longitudinal analysis of antibody response after standard and booster doses of SARS-COV2 vaccination in patients with early breast cancer

Authors: Jinyong Kim, Jiyun Jeong, Chan Mi Lee, Dae-Won Lee, Chang Kyung Kang, Pyeong Gyun Choe, Nam Joong Kim, Myoung-don Oh, Chang-Han Lee, Wan Beom Park, Kyung-Hun Lee, Seock-Ah Im

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: SARS-CoV-2, COVID-19, breast cancer, neutralizing antibodies, serological response, adjuvant chemotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1028102/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/98cdd0f71c1f43e0877981bc8e8ce001

Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts

Authors: Deukchae Na, Jeesoo Chae, Sung-Yup Cho, Wonyoung Kang, Ahra Lee, Seoyeon Min, Jinjoo Kang, Min Jung Kim, Jaeyong Choi, Woochan Lee, Dongjin Shin, Ahrum Min, Yu-Jin Kim, Kyung-Hun Lee, Tae-Yong Kim, Yun-Suhk Suh, Seong-Ho Kong, Hyuk-Joon Lee, Woo-Ho Kim, Hansoo Park, Seock-Ah Im, Han-Kwang Yang, Charles Lee, Jong-Il Kim

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/08fe478b004a4631b3a74073129531e8

Circulating tumor DNA sequencing in colorectal cancer patients treated with first-line chemotherapy with anti-EGFR

Authors: Yoojoo Lim, Sheehyun Kim, Jun-Kyu Kang, Hwang-Phill Kim, Hoon Jang, Hyojun Han, Hyoki Kim, Min Jung Kim, Kyung-Hun Lee, Seung-Bum Ryoo, Ji Won Park, Seung-Yong Jeong, Kyu Joo Park, Gyeong Hoon Kang, Sae-Won Han, Tae-You Kim

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/743bbc06cf9748eeaadef63b4ff5bb41

Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: A Subgroup Analysis of Asian Patients in the Phase 3 KEYNOTE-240 Trial

Authors: Masatoshi Kudo, Ho Yeong Lim, Ann-Lii Cheng, Yee Chao, Thomas Yau, Sadahisa Ogasawara, Masayuki Kurosaki, Naoki Morimoto, Kazuyoshi Ohkawa, Tatsuya Yamashita, Kyung-Hun Lee, Erluo Chen, Abby B. Siegel, Baek-Yeol Ryoo

Source: Liver Cancer, Vol 10, Iss 3, Pp 275-284 (2021)

Subject Terms: pembrolizumab, programmed death 1, hepatocellular carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.karger.com/Article/FullText/515553; https://doaj.org/toc/2235-1795; https://doaj.org/toc/1664-5553

Access URL: https://doaj.org/article/6811a292141f4067ae7851205840ec6a