The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer

Authors: Chow, Andrew, Uddin, Fathema Z., Liu, Michael, Dobrin, Anton, Nabet, Barzin Y., Mangarin, Levi, Lavin, Yonit, Rizvi, Hira, Tischfield, Sam E., Quintanal-Villalonga, Alvaro, Chan, Joseph M., Shah, Nisargbhai, Allaj, Viola, Manoj, Parvathy, Mattar, Marissa, Meneses, Maximiliano, Landau, Rebecca, Ward, Mariana, Kulick, Amanda, Kwong, Charlene, Wierzbicki, Matthew, Yavner, Jessica, Egger, Jacklynn, Chavan, Shweta S., Farillas, Abigail, Holland, Aliya, Sridhar, Harsha, Ciampricotti, Metamia, Hirschhorn, Daniel, Guan, Xiangnan, Richards, Allison L., Heller, Glenn, Mansilla-Soto, Jorge, Sadelain, Michel, Klebanoff, Christopher A., Hellmann, Matthew D., Sen, Triparna, de Stanchina, Elisa, Wolchok, Jedd D., Merghoub, Taha, Rudin, Charles M.

Source: In Immunity 10 January 2023 56(1):93-106

Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation.

Authors: Roychowdhury, Tanaya, McNutt, Seth W., Pasala, Chiranjeevi, Nguyen, Hieu T., Thornton, Daniel T., Sharma, Sahil, Botticelli, Luke, Digwal, Chander S., Joshi, Suhasini, Yang, Nan, Panchal, Palak, Chakrabarty, Souparna, Bay, Sadik, Markov, Vladimir, Kwong, Charlene, Lisanti, Jeanine, Chung, Sun Young, Ginsberg, Stephen D., Yan, Pengrong, De Stanchina, Elisa

Source: Nature Communications; 10/19/2024, Vol. 15 Issue 1, p1-28, 28p

Subject Terms: PLURIPOTENT stem cells, CELL physiology, CANCER stem cells, POST-translational modification, CELL proliferation