Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis

Authors: Kosaku Okuda, Kengo Nakahara, Akihiro Ito, Yuta Iijima, Ryosuke Nomura, Ashutosh Kumar, Kana Fujikawa, Kazuya Adachi, Yuki Shimada, Satoshi Fujio, Reina Yamamoto, Nobumasa Takasugi, Kunishige Onuma, Mitsuhiko Osaki, Futoshi Okada, Taichi Ukegawa, Yasuo Takeuchi, Norihisa Yasui, Atsuko Yamashita, Hiroyuki Marusawa, Yosuke Matsushita, Toyomasa Katagiri, Takahiro Shibata, Koji Uchida, Sheng-Yong Niu, Nhi B. Lang, Tomohiro Nakamura, Kam Y. J. Zhang, Stuart A. Lipton, Takashi Uehara

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2948479591604774a634757fd4634fae

Ultra‐Rapid and Specific Gelation of Collagen Molecules for Transparent and Tough Gels by Transition Metal Complexation

Authors: Tomoyuki Suezawa, Naoko Sasaki, Yuichi Yukawa, Nazgul Assan, Yuta Uetake, Kunishige Onuma, Rino Kamada, Daisuke Tomioka, Hidehiro Sakurai, Ryohei Katayama, Masahiro Inoue, Michiya Matsusaki

Source: Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)

Subject Terms: 3D‐cell culture, collagen, healing property, rapid gelation, transparency, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/0dab417cad3f447aaf00e41ec9b38753

Tracking the growth fate of single cells and isolating slow-growing cells in human colorectal cancer organoids

Authors: Roberto Coppo, Jumpei Kondo, Kunishige Onuma, Masahiro Inoue

Source: STAR Protocols, Vol 4, Iss 3, Pp 102395- (2023)

Subject Terms: Cell Culture, Cell Isolation, Single Cell, Cancer, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166723003623; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/34d7c884333045f9a11d1653dd85c2de

Oxygen metabolism analysis of a single organoid for non-invasive discrimination of cancer subpopulations with different growth capabilities

Authors: Yuji Nashimoto, Shotaro Shishido, Kunishige Onuma, Kosuke Ino, Masahiro Inoue, Hitoshi Shiku

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: scanning electrochemical microscopy (SECM), intratumor heterogeneity (ITH), patient-derived cancer organoids, oxygen metabolism, drug screening platform, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1184325/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/d286aac2c91644aea7ce868ab33afa14

Distinct but interchangeable subpopulations of colorectal cancer cells with different growth fates and drug sensitivity

Authors: Roberto Coppo, Jumpei Kondo, Keita Iida, Mariko Okada, Kunishige Onuma, Yoshihisa Tanaka, Mayumi Kamada, Masayuki Ohue, Kenji Kawada, Kazutaka Obama, Masahiro Inoue

Source: iScience, Vol 26, Iss 2, Pp 105962- (2023)

Subject Terms: Therapy, Cell biology, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223000391; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/420f2737e0a044ecac30f47fd7df08ca

Ozone augments interleukin-8 production induced by ambient particulate matter

Authors: Jun Kurai, Kunishige Onuma, Hiroyuki Sano, Futoshi Okada, Masanari Watanabe

Source: Genes and Environment, Vol 40, Iss 1, Pp 1-8 (2018)

Subject Terms: Antioxidant, Interleukin-6, Interleukin-8, Ozone, Particulate matter, Pro-inflammatory cytokine, Ecology, QH540-549.5, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s41021-018-0102-7; https://doaj.org/toc/1880-7062

Access URL: https://doaj.org/article/ab3037f64f6b4e3a9138d420603b3bcb

Hepatocyte differentiation from mouse liver ductal organoids by transducing 4 liver-specific transcription factors.

Authors: Katsuhiro Tomofuji, Jumpei Kondo, Kunishige Onuma, Coppo, Roberto, Hiroshi Horie, Koki Oyama, Eiji Miyoshi, Ken Fukumitsu, Takamichi Ishii, Etsuro Hatano, Masahiro Inoue

Source: Hepatology Communications; May2023, Vol. 7 Issue 5, p1-16, 16p

Elevated oxidative stress in erythrocytes due to a SOD1 deficiency causes anaemia and triggers autoantibody production.

Authors: Yoshihito Iuchi, Futoshi Okada, Kunishige Onuma, Tadashi Onoda, Hironobu Asao, Masanobu Kobayashi, Junichi Fujii

Source: Biochemical Journal; 2007, Vol. 402 Issue 2, p219-227, 9p

Subject Terms: REACTIVE oxygen species, OXIDATIVE stress, SUPEROXIDES, ERYTHROCYTES, AUTOANTIBODIES, ERYTHROPOIESIS