Therapy enhancing chromosome instability may be advantageous for IDH1^R132H/WT gliomas.

Authors: Goncharov, Nikolay V, Baklanov, Ivan N, Gulaia, Valeriia S, Shuliak, Anastasiia P, Lanskikh, Daria V, Zhmenia, Valeriia M, Shmelev, Mikhail E, Shved, Nikita A, Wu, Jing, Liskovykh, Mikhail, Larionov, Vladimir, Kouprina, Natalay, Kumeiko, Vadim V

Source: NAR Cancer; Mar2025, Vol. 7 Issue 1, p1-19, 19p

Biosynthesis of Functional Silver Nanoparticles Using Callus and Hairy Root Cultures of Aristolochia manshuriensis.

Authors: Yugay, Yulia A.¹, yuya1992@mail.ru, Sorokina, Maria R.¹, sorokina.96@gmail.com, Grigorchuk, Valeria P.¹, kera1313@mail.ru, Rusapetova, Tatiana V.¹, avramenko.dvo@gmail.com, Silant'ev, Vladimir E.^2,3, madiva@inbox.ruvladimir.silantyev@gmail.com, Egorova, Anna E.⁴, bioanna95@list.ru, Adedibu, Peter A.⁵, adeoluadedibu@gmail.com, Kudinova, Olesya D.¹, olesya55@list.ru, Vasyutkina, Elena A.¹, levina@biosoil.ru, Ivanov, Vladimir V.⁶, dom101@mail.ru, Karabtsov, Alexander A.⁶, karabzov@fegi.ru, Mashtalyar, Dmitriy V.³, Degtyarenko, Anton I.¹, 77sat7@gmail.com, Grishchenko, Olga V.¹, crab_ol@mail.ru, Kumeiko, Vadim V.^2,7, vkumeiko@yandex.ru, Bulgakov, Victor P.¹, bulgakov@ibss.dvo.ru, Shkryl, Yury N.^1,5, yn80@mail.ru

Source: Journal of Functional Biomaterials; Sep2023, Vol. 14 Issue 9, p451, 15p

Aptamer's Structure Optimization for Better Diagnosis and Treatment of Glial Tumors.

Authors: Koshmanova, Anastasia A., Artyushenko, Polina V., Shchugoreva, Irina A., Fedotovskaya, Victoriya D., Luzan, Natalia A., Kolovskaya, Olga S., Zamay, Galina S., Lukyanenko, Kirill A., Veprintsev, Dmitriy V., Khilazheva, Elena D., Zamay, Tatiana N., Ivanova, Daria A., Kastyuk, Maria R., Lapin, Ivan N., Svetlichnyi, Valery A., Tomilin, Felix N., Shved, Nikita A., Gulaia, Valeriia S., Kumeiko, Vadim V., Berezovski, Maxim V.

Source: Cancers; Dec2024, Vol. 16 Issue 23, p4111, 17p

Subject Terms: DNA analysis, OLIGONUCLEOTIDE arrays, IN vitro studies, FLOW cytometry, GLIOMAS, RESEARCH funding, ANISOTROPY, CELL lines, MOLECULAR models, MOLECULAR structure, ENDOTHELIAL cells, MOLECULAR biology, MICROSCOPY, FLUORIMETRY, DNA-binding proteins

IDH1 R132H and TP53 R248Q Mutations Modulate Glioma Cell Migration and Adhesion on Different ECM Components.

Authors: Shmelev, Mikhail E., Pilnik, Andrei A., Shved, Nikita A., Penkova, Alina O., Gulaia, Valeriia S., Kumeiko, Vadim V.

Source: International Journal of Molecular Sciences; Nov2024, Vol. 25 Issue 22, p12178, 17p

Subject Terms: CANCER cell migration, CHONDROITIN sulfates, ATOMIC force microscopy, CYTIDINE deaminase, CELL migration, CELL adhesion

Immune state correlates with histopathological level and reveals molluscan health in populations of Modiolus kurilensis by integral health index (IHI)

Authors: Kumeiko, Vadim V., Sokolnikova, Yulia N., Grinchenko, Andrei V., Mokrina, Maria S., Kniazkina, Marina I.

Source: In Journal of Invertebrate Pathology May 2018 154:42-57

Rational Design of Pectin–Chitosan Polyelectrolyte Nanoparticles for Enhanced Temozolomide Delivery in Brain Tumor Therapy.

Authors: Silant'ev, Vladimir E., Belousov, Andrei S., Trukhin, Fedor O., Struppul, Nadezhda E., Shmelev, Mikhail E., Patlay, Aleksandra A., Shatilov, Roman A., Kumeiko, Vadim V.

Source: Biomedicines; Jul2024, Vol. 13 Issue 7, p1393, 23p

Subject Terms: TARGETED drug delivery, NON-target organisms, BRAIN tumors, DRUG delivery systems, YOUNG'S modulus

Study of the Impact of the Parasitic Microalgae Coccomyxa parasitica on the Health of Bivalve Modiolus kurilensis.

Authors: Tumas, Ayna V., Slatvinskaya, Veronika A., Kumeiko, Vadim V., Sokolnikova, Yulia N.

Source: Microorganisms; May2024, Vol. 12 Issue 5, p997, 23p

Subject Terms: LYSOSOMES, BIVALVES, MICROALGAE, PARASITIC wasps, REACTIVE oxygen species, ALKALINE phosphatase

Preparation and Characterization of Hydrogel Films and Nanoparticles Based on Low-Esterified Pectin for Anticancer Applications.

Authors: Patlay, Aleksandra A., Belousov, Andrei S., Silant'ev, Vladimir E., Shatilov, Roman A., Shmelev, Mikhail E., Kovalev, Valeri V., Perminova, Irina V., Baklanov, Ivan N., Kumeiko, Vadim V.

Source: Polymers (20734360); Aug2023, Vol. 15 Issue 15, p3280, 18p

Subject Terms: PECTINS, DRUG delivery systems, HYDROGELS, CELL metabolism, NANOCARRIERS, NANOPARTICLES, ZETA potential, GELATION

Enhanced Production of Nitrogenated Metabolites with Anticancer Potential in Aristolochia manshuriensis Hairy Root Cultures.

Authors: Shkryl, Yury N., Tchernoded, Galina K., Yugay, Yulia A., Grigorchuk, Valeria P., Sorokina, Maria R., Gorpenchenko, Tatiana Y., Kudinova, Olesya D., Degtyarenko, Anton I., Onishchenko, Maria S., Shved, Nikita A., Kumeiko, Vadim V., Bulgakov, Victor P.

Source: International Journal of Molecular Sciences; Jul2023, Vol. 24 Issue 14, p11240, 17p

Subject Terms: ARISTOLOCHIA, RHIZOBIUM rhizogenes, TRIPLE-negative breast cancer, ARISTOLOCHIC acid, CHINESE medicine, CALLUS (Botany), CELL suspensions

How to Develop Drug Delivery System Based on Carbohydrate Nanoparticles Targeted to Brain Tumors.

Authors: Silant'ev, Vladimir E., Shmelev, Mikhail E., Belousov, Andrei S., Patlay, Aleksandra A., Shatilov, Roman A., Farniev, Vladislav M., Kumeiko, Vadim V.

Source: Polymers (20734360); Jun2023, Vol. 15 Issue 11, p2516, 27p

Subject Terms: DRUG delivery systems, BRAIN tumors, TARGETED drug delivery, NANOPARTICLE synthesis, NANOPARTICLES, CARBOHYDRATES

Kidney-Related Function of Mitochondrial Protein Mitoregulin.

Authors: Averina, Olga A., Permyakov, Oleg A., Emelianova, Mariia A., Guseva, Ekaterina A., Grigoryeva, Olga O., Lovat, Maxim L., Egorova, Anna E., Grinchenko, Andrei V., Kumeiko, Vadim V., Marey, Maria V., Manskikh, Vasily N., Dontsova, Olga A., Vyssokikh, Mikhail Y., Sergiev, Petr V.

Source: International Journal of Molecular Sciences; May2023, Vol. 24 Issue 10, p9106, 13p

Subject Terms: MITOCHONDRIAL proteins, KIDNEY tubules, KNOCKOUT mice, KIDNEYS, OXIDATIVE phosphorylation, GLOMERULAR filtration rate, PROXIMAL kidney tubules

Research Topics of the Bioinformatics of Gene Regulation.

Authors: Orlov, Yuriy L., Anashkina, Anastasia A., Kumeiko, Vadim V., Chen, Ming, Kolchanov, Nikolay A.

Source: International Journal of Molecular Sciences; May2023, Vol. 24 Issue 10, p8774, 5p

Subject Terms: GENETIC regulation, SCIENTIFIC literature, CATTLE breeds, DNA analysis, SCIENTIFIC knowledge, BIOLOGICAL evolution

Mitoregulin Contributes to Creatine Shuttling and Cardiolipin Protection in Mice Muscle.

Authors: Averina, Olga A., Permyakov, Oleg A., Emelianova, Mariia A., Grigoryeva, Olga O., Lovat, Maxim L., Egorova, Anna E., Grinchenko, Andrei V., Kumeiko, Vadim V., Marey, Maria V., Manskikh, Vasily N., Dontsova, Olga A., Vysokikh, Mikhail Yu., Sergiev, Petr V.

Source: International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 8, p7589, 12p

Subject Terms: CARDIOLIPIN, KREBS cycle, CREATINE kinase, KNOCKOUT mice, FATIGUE (Physiology)

Nanomechanical Signatures in Glioma Cells Depend on CD44 Distribution in IDH1 Wild-Type but Not in IDH1R132H Mutant Early-Passage Cultures.

Authors: Shmelev, Mikhail E., Farniev, Vladislav M., Shved, Nikita A., Kumeiko, Vadim V.

Source: International Journal of Molecular Sciences; Feb2023, Vol. 24 Issue 4, p4056, 16p

Subject Terms: GLIOMAS, CD44 antigen, ATOMIC force microscopy, CELL populations, ELASTIC modulus, CELL culture

Nanomechanical and Morphological AFM Mapping of Normal Tissues and Tumors on Live Brain Slices Using Specially Designed Embedding Matrix and Laser-Shaped Cantilevers.

Authors: Farniev, Vladislav M., Shmelev, Mikhail E., Shved, Nikita A., Gulaia, Valeriia S., Biktimirov, Arthur R., Zhizhchenko, Alexey Y., Kuchmizhak, Aleksandr A., Kumeiko, Vadim V.

Source: Biomedicines; Jul2022, Vol. 10 Issue 7, pN.PAG-N.PAG, 20p

Subject Terms: ATOMIC force microscopy, SCANNING electron microscopy, CANTILEVERS, LASER pulses, MEDICAL research

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Cell and Tissue Nanomechanics: From Early Development to Carcinogenesis.

Authors: Shmelev, Mikhail E., Titov, Sergei I., Belousov, Andrei S., Farniev, Vladislav M., Zhmenia, Valeriia M., Lanskikh, Daria V., Penkova, Alina O., Kumeiko, Vadim V.

Source: Biomedicines; Feb2022, Vol. 10 Issue 2, p345, 1p

Subject Terms: NUCLEAR matrix, NANOMECHANICS, EXTRACELLULAR matrix, STEM cell niches, CELLULAR mechanics

A Novel C1q Domain-Containing Protein Isolated from the Mollusk Modiolus kurilensis Recognizing Glycans Enriched with Acidic Galactans and Mannans.

Authors: Grinchenko, Andrei V., von Kriegsheim, Alex, Shved, Nikita A., Egorova, Anna E., Ilyaskina, Diana V., Karp, Tatiana D., Goncharov, Nikolay V., Petrova, Irina Y., Kumeiko, Vadim V.

Source: Marine Drugs; Dec2021, Vol. 19 Issue 12, p668-668, 1p

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Advances in the Understanding of Skin Cancer: Ultraviolet Radiation, Mutations, and Antisense Oligonucleotides as Anticancer Drugs.

Authors: Laikova, Kateryna V., Oberemok, Volodymyr V., Krasnodubets, Alisa M., Gal'chinsky, Nikita V., Useinov, Refat Z., Novikov, Ilya A., Temirova, Zenure Z., Gorlov, Mikhail V., Shved, Nikita A., Kumeiko, Vadim V., Makalish, Tatiana P., Bessalova, Evgeniya Y., Fomochkina, Iryna I., Esin, Andrey S., Volkov, Mikhail E., Kubyshkin, Anatoly V.

Source: Molecules; 4/15/2019, Vol. 24 Issue 8, p1516-1516, 1p

Subject Terms: SKIN cancer, ULTRAVIOLET radiation, OLIGONUCLEOTIDES, ANTINEOPLASTIC agents, CANCER cells