The anti-atherosclerotic effect of chronic AT1 receptor blocker treatment also depends on the ACE2/Ang(1−7)/Mas axis

Authors: Klersy, Tobias ^{a, 1}, Achner, Leonie ^{a, 1}, Fels, Benedikt ^b, Rezende, Flavia ^{c, d}, Lopez, Melina ^{c, d}, Alenina, Natalia ^e, Spiecker, Frauke ^a, Stölting, Ines ^a, Häuser, Walter ^a, Reinberger, Tobias ^{f, g}, Aherrahrou, Zouhair ^{f, g}, Kuenne, Carsten ^h, Vahldieck, Carl ^b, Matschl, Urte ⁱ, Hille, Susanne ^{g, j}, Bader, Michael ^{e, k, l, m}, Brandes, Ralf P. ^{c, d}, Müller, Oliver J. ^{g, j}, Kusche-Vihrog, Kristina ^{b, g}, Raasch, Walter ^{a, g, n, ⁎}

Source: In Biomedicine & Pharmacotherapy May 2025 186

Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression

Authors: Boonsanay, Verawan, Mosa, Mohammed H., Looso, Mario, Weichenhan, Dieter, Ceteci, Fatih, Pudelko, Lorenz, Lechel, Andre, Michel, Christian S., Künne, Carsten, Farin, Henner F., Plass, Christoph, Greten, Florian R.

Source: In Gastroenterology February 2023 164(2):214-227

i2dash: Creation of Flexible, Interactive, and Web-based Dashboards for Visualization of Omics Data

Authors: Ustjanzew, Arsenij, Preussner, Jens, Bentsen, Mette, Kuenne, Carsten, Looso, Mario

Source: In Genomics, Proteomics & Bioinformatics June 2022 20(3):568-577

TF-COMB – Discovering grammar of transcription factor binding sites

Authors: Bentsen, Mette, Heger, Vanessa, Schultheis, Hendrik, Kuenne, Carsten, Looso, Mario

Source: Computational and Structural Biotechnology Journal. 20:4040-4051

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190062989.0x000001&indx=1&recIds=ETOCvdc_100190062989.0x000001

Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease

Authors: Qi, Hui, Liu, Hang, Pullamsetti, Soni Savai, Günther, Stefan, Kuenne, Carsten, Atzberger, Ann, Sommer, Natascha, Hadzic, Stefan, Günther, Andreas, Weissmann, Norbert, Zhou, Yonggang, Yuan, Xuejun, Braun, Thomas

Source: Circulation. 144(13):1042-1058

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189189848.0x000001&indx=1&recIds=ETOCvdc_100189189848.0x000001

Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles

Authors: Sreenivasan, Krishnamoorthy, Ianni, Alessandro, Künne, Carsten, Strilic, Boris, Günther, Stefan, Perdiguero, Eusebio, Krüger, Marcus, Spuler, Simone, Offermanns, Stefan, Gómez-del Arco, Pablo, Redondo, Juan Miguel, Munoz-Canoves, Pura, Kim, Johnny, Braun, Thomas

Source: In Cell Reports 19 May 2020 31(7)

ADPGK‐AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth

Authors: Karger, Annika, Mansouri, Siavash, Leisegang, Matthias S, Weigert, Andreas, Günther, Stefan, Kuenne, Carsten, Wittig, Ilka, Zukunft, Sven, Klatt, Stephan, Aliraj, Blerina, Klotz, Laura V, Winter, Hauke, Mahavadi, Poornima, Fleming, Ingrid, Ruppert, Clemens, Witte, Biruta, Alkoudmani, Ibrahim, Gattenlöhner, Stefan, Grimminger, Friedrich, Seeger, Werner, Pullamsetti, Soni Savai, Savai, Rajkumar

Source: EMBO journal. 42(18)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193007843.0x000001&indx=1&recIds=ETOCvdc_100193007843.0x000001

AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration

Authors: Beisaw, Arica, Kuenne, Carsten, Guenther, Stefan, Dallmann, Julia, Wu, Chi-Chung, Bentsen, Mette, Looso, Mario, Stainier, Didier Y.R.

Source: Circulation research. 126(12):1760-1778

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190132345.0x000001&indx=1&recIds=ETOCvdc_100190132345.0x000001

Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury.

Authors: Zhou, Luping, Pereiro, Marc Torres, Li, Yanqun, Derigs, Marcus, Kuenne, Carsten, Hielscher, Thomas, Huang, Wei, Kränzlin, Bettina, Tian, Gang, Kobayashi, Kazuhiro, Lu, Gia-Hue Natalie, Roedl, Kevin, Schmidt, Claudia, Günther, Stefan, Looso, Mario, Huber, Johannes, Xu, Yong, Wiech, Thorsten, Sperhake, Jan-Peter, Wichmann, Dominic

Source: Science Translational Medicine; 10/2/2024, Vol. 16 Issue 767, p1-16, 16p

Subject Terms: COVID-19, GLUCOCORTICOID receptors, DOUBLE-strand DNA breaks, ACUTE kidney failure, RENAL biopsy

Oncogenic Amplification of Zygotic Dux Factors in Regenerating p53-Deficient Muscle Stem Cells Defines a Molecular Cancer Subtype

Authors: Preussner, Jens, Zhong, Jiasheng, Sreenivasan, Krishnamoorthy, Günther, Stefan, Engleitner, Thomas, Künne, Carsten, Glatzel, Markus, Rad, Roland, Looso, Mario, Braun, Thomas, Kim, Johnny

Source: In Cell Stem Cell 6 December 2018 23(6):794-805

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice

Authors: Rezende, Flávia, Moll, Franziska, Walter, Maria, Helfinger, Valeska, Hahner, Fabian, Janetzko, Patrick, Ringel, Christian, Weigert, Andreas, Fleming, Ingrid, Weissmann, Norbert, Kuenne, Carsten, Looso, Mario, Rieger, Michael A., Nawroth, Peter, Fleming, Thomas, Brandes, Ralf P., Schröder, Katrin

Source: In Redox Biology May 2018 15:12-21

Genetic compensation triggered by mutant mRNA degradation

Authors: El-Brolosy, Mohamed, Kontarakis, Zacharias, Rossi, Andrea, Kuenne, Carsten, Günther, Stefan, Fukuda, Nana, Kikhi, Khrievono, Boezio, Giulia, Takacs, Carter M., Lai, Shih-Lei, Fukuda, Ryuichi, Gerri, Claudia, Giraldez, Antonio, Stainier, Didier

Source: Nature. 568(7751):193-197

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132431068.0x000001&indx=1&recIds=ETOCvdc_100132431068.0x000001

Induction of interferon-stimulated genes and cellular stress pathways by morpholinos in zebrafish

Authors: Lai, Jason K.H., Gagalova, Kristina K., Kuenne, Carsten, El-Brolosy, Mohamed A., Stainier, Didier Y.R.

Source: Developmental biology. 454(1):21-28

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087347966.0x000001&indx=1&recIds=ETOCvdc_100087347966.0x000001

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate

Authors: Gao, Rui, Liang, Xingqun, Cheedipudi, Sirisha, Cordero, Julio, Jiang, Xue, Zhang, Qingquan, Caputo, Luca, Günther, Stefan, Kuenne, Carsten, Ren, Yonggang, Bhattacharya, Shoumo, Yuan, Xuejun, Barreto, Guillermo, Chen, Yihan, Braun, Thomas, Evans, Sylvia M., Sun, Yunfu, Dobreva, Gergana

Source: Cell research. 29(6):486-501

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153476308.0x000001&indx=1&recIds=ETOCvdc_100153476308.0x000001

Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients

Authors: Spallotta, Francesco, Cencioni, Chiara, Atlante, Sandra, Garella, Davide, Cocco, Mattia, Mori, Mattia, Mastrocola, Raffaella, Kuenne, Carsten, Guenther, Stefan, Nanni, Simona, Azzimato, Valerio, Zukunft, Sven, Kornberger, Angela, Sürün, Duran, Schnütgen, Frank, von Melchner, Harald, Di Stilo, Antonella, Aragno, Manuela, Braspenning, Maarten, van Criekinge, Wim, De Blasio, Miles J., Ritchie, Rebecca H., Zaccagnini, Germana, Martelli, Fabio, Farsetti, Antonella, Fleming, Ingrid, Braun, Thomas, Beiras-Fernandez, Andres, Botta, Bruno, Collino, Massimo, Bertinaria, Massimo, Zeiher, Andreas M., Gaetano, Carlo

Source: Circulation research. 122(1):31-46

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100066172979.0x000001&indx=1&recIds=ETOCvdc_100066172979.0x000001

Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells

Authors: Cencioni, Chiara, Spallotta, Francesco, Savoia, Matteo, Kuenne, Carsten, Guenther, Stefan, Re, Agnese, Wingert, Susanne, Rehage, Maike, Sürün, Duran, Siragusa, Mauro, Smith, Jacob, Schnütgen, Frank, von Melchner, Harald, Rieger, Michael, Martelli, Fabio, Riccio, Antonella, Fleming, Ingrid, Braun, Thomas, Zeiher, Andreas, Farsetti, Antonella, Gaetano, Carlo

Source: Nature communications. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129127952.0x000001&indx=1&recIds=ETOCvdc_100129127952.0x000001

WIlsON: Web-based Interactive Omics VisualizatioN

Authors: Schultheis, Hendrik, Kuenne, Carsten, Preussner, Jens, Wiegandt, Rene, Fust, Annika, Bentsen, Mette, Looso, Mario

Source: Bioinformatics. 35(6):1055-1057

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078792821.0x000001&indx=1&recIds=ETOCvdc_100078792821.0x000001

The homeobox transcription factor DUXBL controls exit from totipotency

Authors: Vega-Sendino, Maria, Lüttmann, Felipe F., Olbrich, Teresa, Chen, Yanpu, Kuenne, Carsten, Stein, Paula, Tillo, Desiree, Carey, Grace I., Zhong, Jiasheng, Savy, Virginia, Radonova, Lenka, Lu, Tianlin, Saykali, Bechara, Kim, Kee-Pyo, Domingo, Catherine N., Schüler, Leah, Günther, Stefan, Bentsen, Mette, Bosnakovski, Darko, Schöler, Hans, Kyba, Michael, Maity, Tapan K., Jenkins, Lisa M., Looso, Mario, Williams, Carmen J., Kim, Johnny, Ruiz, Sergio

Source: Nature Genetics; April 2024, Vol. 56 Issue: 4 p697-709, 13p

Stimulation of glycolysis promotes cardiomyocyte proliferation after injury in adult zebrafish

Authors: Fukuda, Ryuichi, Marín‐Juez, Rubén, El‐Sammak, Hadil, Beisaw, Arica, Ramadass, Radhan, Kuenne, Carsten, Guenther, Stefan, Konzer, Anne, Bhagwat, Aditya M, Graumann, Johannes, Stainier, Didier YR

Source: EMBO reports. 21(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128297207.0x000001&indx=1&recIds=ETOCvdc_100128297207.0x000001

TGF-β Signaling Promotes Tissue Formation during Cardiac Valve Regeneration in Adult Zebrafish

Authors: Bensimon-Brito, Anabela, Ramkumar, Srinath, Boezio, Giulia L.M., Guenther, Stefan, Kuenne, Carsten, Helker, Christian S.M., Sánchez-Iranzo, Héctor, Iloska, Dijana, Piesker, Janett, Pullamsetti, Soni, Mercader, Nadia, Beis, Dimitris, Stainier, Didier Y.R.

Source: Developmental cell. 52(1):9-20.e7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100296564.0x000001&indx=1&recIds=ETOCvdc_100100296564.0x000001