Utilizing literature-based rodent toxicology data to derive potency estimates for quantitative risk assessment

Authors: Boots, Theresa E., Kogel, Alyssa M., Drew, Nathan M., Kuempel, Eileen D.

Source: Nanotoxicology. 15(6):740-760

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125844955.0x000001&indx=1&recIds=ETOCvdc_100125844955.0x000001

A methodology for developing key events to advance nanomaterial-relevant adverse outcome pathways to inform risk assessment

Authors: Halappanavar, Sabina, Ede, James D., Mahapatra, Indrani, Krug, Harald F., Kuempel, Eileen D., Lynch, Iseult, Vandebriel, Rob J., Shatkin, Jo Anne

Source: Nanotoxicology. 15(3):289-310

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117717174.0x000001&indx=1&recIds=ETOCvdc_100117717174.0x000001

Dosimetry of inhaled elongate mineral particles in the respiratory tract: The impact of shape factor

Authors: Asgharian, Bahman, Owen, T. Price, Kuempel, Eileen D., Jarabek, Annie M.

Source: In Toxicology and Applied Pharmacology 15 December 2018 361:27-35

A quantitative framework to group nanoscale and microscale particles by hazard potency to derive occupational exposure limits: Proof of concept evaluation

Authors: Drew, Nathan M., Kuempel, Eileen D., Pei, Ying, Yang, Feng

Source: In Regulatory Toxicology and Pharmacology October 2017 89:253-267

Bayesian evaluation of a physiologically-based pharmacokinetic (PBPK) model of long-term kinetics of metal nanoparticles in rats

Authors: Sweeney, Lisa M., MacCalman, Laura, Haber, Lynne T., Kuempel, Eileen D., Tran, C. Lang

Source: In Regulatory Toxicology and Pharmacology October 2015 73(1):151-163

Evaluating the mechanistic evidence and key data gaps in assessing the potential carcinogenicity of carbon nanotubes and nanofibers in humans

Authors: Kuempel, Eileen D., Jaurand, Marie-Claude, Møller, Peter, Morimoto, Yasuo, Kobayashi, Norihiro, Pinkerton, Kent E., Sargent, Linda M., Vermeulen, Roel C. H., Fubini, Bice, Kane, Agnes B.

Source: Critical reviews in toxicology. 47(1):1-58

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103787223.0x000001&indx=1&recIds=ETOCvdc_100103787223.0x000001

Application of Markov chain Monte Carlo analysis to biomathematical modeling of respirable dust in US and UK coal miners

Authors: Sweeney, Lisa M., Parker, Ann, Haber, Lynne T., Tran, C. Lang, Kuempel, Eileen D.

Source: In Regulatory Toxicology and Pharmacology June 2013 66(1):47-58

Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation

Authors: Kuempel, Eileen D., Sweeney, Lisa M., Morris, John B., Jarabek, Annie M.

Source: Journal of occupational and environmental hygiene. 12:S18-S40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100029261897.0x000001&indx=1&recIds=ETOCvdc_100029261897.0x000001

Increased lung cancer mortality among chrysotile asbestos textile workers is more strongly associated with exposure to long thin fibres

Authors: Loomis, Dana, Dement, John M, Elliott, Leslie, Richardson, David, Kuempel, Eileen D, Stayner, Leslie

Source: Occupational and Environmental Medicine, 2012 Aug 01. 69(8), 564-568.

Access URL: https://www.jstor.org/stable/23567860

Estimates of historical exposures by phase contrast and transmission electron microscopy for pooled exposure—response analyses of North Carolina and South Carolina, USA asbestos textile cohorts

Authors: Dement, John M, Loomis, Dana, Richardson, David, Wolf, Susanne H, Kuempel, Eileen D

Source: Occupational and Environmental Medicine, 2011 Aug 01. 68(8), 593-598.

Access URL: https://www.jstor.org/stable/23048258

Carbon Black: Kuempel et al. Respond

Authors: Kuempel, Eileen D., Schulte, Paul A., Sorahan, Thomas, Caldwell, Jane, Straif, Kurt, Ward, Elizabeth

Source: Environmental Health Perspectives, 2011 Aug 01. 119(8), A333-A334.

Access URL: https://www.jstor.org/stable/41233441

Carbon Nanotube Risk Assessment: Implications for Exposure and Medical Monitoring

Authors: Kuempel, Eileen D.

Source: Journal of Occupational and Environmental Medicine, 2011 Jun 01. 53(6S), S91-S97.

Access URL: https://www.jstor.org/stable/45009810

A Biomathematical Model of Particle Clearance and Retention in the Lungs of Coal Miners: II. Evaluation of Variability and Uncertainty

Authors: Kuempel, Eileen D., Tran, Chi-Lang, Smith, Randall J., Bailer, A.John

Source: In Regulatory Toxicology and Pharmacology August 2001 34(1):88-101

A Biomathematical Model of Particle Clearance and Retention in the Lungs of Coal Miners: I. Model Development

Authors: Kuempel, Eileen D., O'Flaherty, Ellen J. ¹, Stayner, Leslie T., Smith, Randall J., Green, Francis H.Y., Vallyathan, Val

Source: In Regulatory Toxicology and Pharmacology August 2001 34(1):69-87

Methodological issues of using observational human data in lung dosimetry models for particulates

Authors: Kuempel, Eileen D ^*, Tran, Chi-Lang, Bailer, A.John, Smith, Randall J, Dankovic, David A, Stayner, Leslie T

Source: In Science of the Total Environment 2001 274(1):67-77

Chapter 3 - Hazard and Risk Assessment of Workplace Exposure to Engineered Nanoparticles: Methods, Issues, and Carbon Nanotube Case Study

Authors: Kuempel, Eileen D., Castranova, Vincent

Source: In Assessing Nanoparticle Risks to Human Health Edition: Second Edition. 2016:45-82

EVALUATION OF PARTICLE CLEARANCE AND RETENTION KINETICS IN THE LUNGS OF U.S. COAL MINERS.

Authors: Kuempel, Eileen D., Chi-Lang Tran, O'Flaherty, Ellen J., Stayner, Leslie T., Smith, Randall J., Dankovic, David A., Bailer, A. John

Source: Inhalation Toxicology. Jul2000 Supplement 3, Vol. 12, p397. 6p.

Subject Terms: *COAL ash, *LUNGS, *COAL mining, *MASS transfer

Geographic Terms: UNITED States

COMPARISON OF HUMAN AND RODENT LUNG DOSIMETRY MODELS FOR PARTICLE CLEARANCE AND RETENTION.

Authors: Kuempel, Eileen D.¹ (AUTHOR)

Source: Drug & Chemical Toxicology. 2000, Vol. 23 Issue 1, p203-222. 20p. 4 Charts.

Subject Terms: *DRUG dosage, *HAZARDOUS substances, *COAL mining

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Carbon Black.

Authors: McCunney, Robert J.¹ mccunney@MIT.EDU, Morfeld, Peter², Levy, Len³, Muranko, Henry⁴, Kuempel, Eileen D.⁵ ekuempel@cdc.gov, Schulte, Paul A.⁵, Sorahan, Thomas⁶, Caldwell, Jane⁷, Straif, Kurt⁸, Ward, Elizabeth⁹

Source: Environmental Health Perspectives. Aug2011, Vol. 119 Issue 8, pA332-A334. 3p.

Subject Terms: *Carbon, *Carcinogens, *Dose-response relationship in biochemistry, *Environmental exposure, Lung tumors, Occupational hazards, Oxidative stress