Tuning the 3D microenvironment of reprogrammed tubule cells enhances biomimetic modeling of polycystic kidney disease

Authors: Pichler, Roman, Rizzo, Ludovica, Tröndle, Kevin, Bühler, Michaela, Brucker, Hanna, Müller, Anna-Lena, Grand, Kelli, Farè, Silvia, Viau, Amandine, Kaminski, Michael M., Kuehn, E. Wolfgang, Koch, Fritz, Zimmermann, Stefan, Koltay, Peter, Lienkamp, Soeren S.

Source: In Biomaterials December 2022 291

The renal inflammatory network of nephronophthisis

Authors: Quatredeniers, Marceau, Bienaimé, Frank, Ferri, Giulia, Isnard, Pierre, Porée, Esther, Billot, Katy, Birgy, Eléonore, Mazloum, Manal, Ceccarelli, Salomé, Silbermann, Flora, Braeg, Simone, Nguyen-Khoa, Thao, Salomon, Rémi, Gubler, Marie-Claire, Kuehn, E Wolfgang, Saunier, Sophie, Viau, Amandine

Source: Human molecular genetics. 31(13):2121-2136

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163722647.0x000001&indx=1&recIds=ETOCvdc_100163722647.0x000001

Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner

Authors: Peintner, Lukas, Venkatraman, Anusha, Waeldin, Astrid, Hofherr, Alexis, Busch, Tilman, Voronov, Alexander, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Borner, Christoph

Source: Autophagy. 17(9):2384-2400

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138420023.0x000001&indx=1&recIds=ETOCvdc_100138420023.0x000001

Ift88, but not Kif3a, is required for establishment of the periciliary membrane compartment

Authors: Kotsis, Fruzsina, Janusch, Heike, Li, Yujie, Viau, Amandine, Epting, Daniel, Kramer-Zucker, Albrecht, Walz, Gerd, Nitschke, Roland, Lorentzen, Esben, Ganner, Athina, Neumann-Haefelin, Elke, Kuehn, E. Wolfgang, Boehlke, Christopher

Source: Biochemical and biophysical research communications. 584:19-25

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148121230.0x000001&indx=1&recIds=ETOCvdc_100148121230.0x000001

TermineR: Extracting information on endogenous proteolytic processing from shotgun proteomics data.

Authors: Cosenza‐Contreras, Miguel, Seredynska, Adrianna, Vogele, Daniel, Pinter, Niko, Brombacher, Eva, Cueto, Ruth Fiestas, Dinh, Thien‐Ly Julia, Bernhard, Patrick, Rogg, Manuel, Liu, Junwei, Willems, Patrick, Stael, Simon, Huesgen, Pitter F., Kuehn, E. Wolfgang, Kreutz, Clemens, Schell, Christoph, Schilling, Oliver

Source: Proteomics; Oct2024, Vol. 24 Issue 19, p1-11, 11p

Divergent function of polycystin 1 and polycystin 2 in cell size regulation

Authors: Viau, Amandine, Kotsis, Fruzsina, Boehlke, Christopher, Braeg, Simone, Klein, Marinella, Nitschke, Roland, Walz, Gerd, Kuehn, E. Wolfgang

Source: Biochemical and biophysical research communications. 521(2):290-295

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094775749.0x000001&indx=1&recIds=ETOCvdc_100094775749.0x000001

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

Authors: Thedieck, Kathrin, Holzwarth, Birgit, Prentzell, Mirja Tamara, Boehlke, Christopher, Kläsener, Kathrin, Ruf, Stefanie, Sonntag, Annika Gwendolin, Maerz, Lars, Grellscheid, Sushma-Nagaraja, Kremmer, Elisabeth, Nitschke, Roland, Kuehn, E. Wolfgang, Jonker, Johan W., Groen, Albert K., Reth, Michael, Hall, Michael N., Baumeister, Ralf

Source: In Cell 15 August 2013 154(4):859-874

Inversin relays Frizzled-8 signals to promote proximal pronephros development

Authors: Lienkamp, Soeren, Ganner, Athina, Boehlke, Christopher, Schmidt, Thorsten, Arnold, Sebastian J., Schäfer, Tobias, Romaker, Daniel, Schuler, Julia, Hoff, Sylvia, Powelske, Christian, Eifler, Annekathrin, Krönig, Corinna, Bullerkotte, Axel, Nitschke, Roland, Kuehn, E. Wolfgang, Kim, Emily, Burkhardt, Hans, Brox, Thomas, Ronneberger, Olaf, Gloy, Joachim, Walz, Gerd, Anderson, Kathryn V.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Nov . 107(47), 20388-20393.

Access URL: https://www.jstor.org/stable/25756707

Scribble Participates in Hippo Signaling and Is Required for Normal Zebrafish Pronephros Development

Authors: Skouloudaki, Kassiani, Puetz, Michael, Simons, Matias, Courbard, Jean-Remy, Boehlke, Christopher, Hartleben, Björn, Engel, Christina, Moeller, Marcus J., Englert, Christoph, Bollig, Frank, Schäfer, Tobias, Ramachandran, Haribaskar, Mlodzik, Marek, Huber, Tobias B., Kuehn, E. Wolfgang, Kim, Emily, Kramer-Zucker, Albrecht, Walz, Gerd, Anderson, Kathryn V.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2009 May . 106(21), 8579-8584.

Access URL: https://www.jstor.org/stable/40482724

TRPP2 and TRPV4 Form a Polymodal Sensory Channel Complex

Authors: Köttgen, Michael, Buchholz, Björn, Garcia-Gonzalez, Miguel A., Kotsis, Fruzsina, Fu, Xiao, Doerken, Mara, Boehlke, Christopher, Steffl, Daniel, Tauber, Robert, Wegierski, Tomasz, Nitschke, Roland, Suzuki, Makoto, Kramer-Zucker, Albrecht, Germino, Gregory G., Watnick, Terry, Prenen, Jean, Nilius, Bernd, Kuehn, E. Wolfgang, Walz, Gerd

Source: The Journal of Cell Biology, 2008 Aug 01. 182(3), 437-447.

Access URL: https://www.jstor.org/stable/20476067

mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression

Authors: Huber, Tobias B., Walz, Gerd, Kuehn, E Wolfgang ^*

Source: In Kidney International 1 March 2011 79(5):502-511

Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2

Authors: Kuehn, E. Wolfgang, Hirt, Marc N., John, Anne-K., Muehlenhardt, Petra, Boehlke, Christopher, Pütz, Michael, Kramer-Zucker, Albrecht G., Bashkurov, Mikhail, van de Weyer, Philipp S., Kotsis, Fruzsina, Walz, Gerd

Source: In Biochemical and Biophysical Research Communications 2007 364(4):861-866

renal inflammatory network of nephronophthisis.

Authors: Quatredeniers, Marceau, Bienaimé, Frank, Ferri, Giulia, Isnard, Pierre, Porée, Esther, Billot, Katy, Birgy, Eléonore, Mazloum, Manal, Ceccarelli, Salomé, Silbermann, Flora, Braeg, Simone, Nguyen-Khoa, Thao, Salomon, Rémi, Gubler, Marie-Claire, Kuehn, E Wolfgang, Saunier, Sophie, Viau, Amandine

Source: Human Molecular Genetics; Jul2022, Vol. 31 Issue 13, p2121-2136, 16p

A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9

Authors: van de Weyer, Philipp S., Muehlfeit, Michael, Klose, Christoph, Bonventre, Joseph V., Walz, Gerd, Kuehn, E. Wolfgang

Source: In Biochemical and Biophysical Research Communications 2006 351(2):571-576

Kidney injury molecule-1 expression in murine polycystic kidney disease.

Authors: Kuehn, E. Wolfgang, Park, Kwon Moo, Somlo, Stefan

Source: American Journal of Physiology; December 2002 pt2, Vol. 283 Issue 6, pF1326-F1336, 11p

Patient Cyst Type Composition Predicts Responsiveness to Therapeutic Intervention in Autosomal Polycystic Kidney Disease

Authors: Roeles, Johannes, Giesler, Axel, Braesen, Jan H., Schmitz, Jessica, Friedersdorff, Frank, Kottgen, Michael, Kuehn, E. Wolfgang, Schmitt, Roland, Schmidt-Ott, Kai M., Hinze, Christian

Source: Journal of the American Society of Nephrology; October 2024, Vol. 35 Issue: 10, Number 10 Supplement 10

Identification of pathological transcription in autosomal dominant polycystic kidney disease epithelia.

Authors: Friedrich, Sebastian, Müller, Hannah, Riesterer, Caroline, Schüller, Hannah, Friedrich, Katja, Wörner, Carlotta Leonie, Busch, Tilman, Viau, Amandine, Kuehn, E. Wolfgang, Köttgen, Michael, Hofherr, Alexis

Source: Scientific Reports; 7/23/2021, Vol. 11 Issue 1, p1-17, 17p

Subject Terms: POLYCYSTIC kidney disease, GENETIC mutation, CYSTIC kidney disease, EPITHELIAL cells, LABORATORY mice

Kinesin-2 mediates apical endosome transport during epithelial lumen formation

Authors: Li, Dongying, Kuehn, E Wolfgang, Prekeris, Rytis

Source: Cellular logistics. 4(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050677505.0x000001&indx=1&recIds=ETOCvdc_100050677505.0x000001

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