Interactions between vitamin D deficiency and inflammation on diabetes risk: data from 336,500 UK Biobank adults

Authors: Kositsawat, Jatupol ^{a, 1, ⁎}, Zhao, Shangshu ^{b, 1}, Kuchel, George A. ^a, Barry, Lisa C. ^a, Fortinsky, Richard H. ^a, Kirk, Ben ^{c, d}, Duque, Gustavo ^{e, f}, Kuo, Chia-Ling ^b

Source: In The Journal of nutrition, health and aging February 2025 29(2)

Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function

Authors: Wang, Binsheng ^{1, 2, 14}, Wang, Lichao ^{1, 2, 14}, Gasek, Nathan S. ^{1, 2}, Kuo, Chia-Ling ^{1, 3}, Nie, Jia ⁴, Kim, Taewan ^{1, 2}, Yan, Pengyi ^{1, 2}, Zhu, Junyu ^{1, 2}, Torrance, Blake L. ^{1, 5}, Zhou, Yueying ^{1, 6}, Flores, Lisa C. ⁷, Allen, Colton ⁷, Andrade, Allison M. ¹, Guo, Chun ¹, Cohn, Rachel L. ^{1, 2}, Jellison, Evan R. ⁵, Bartley, Jenna M. ^{1, 5}, Kuchel, George A. ¹, Li, Sheng ⁸, Pirtskhalava, Tamar ^{4, 9}, Tchkonia, Tamar ^{4, 9}, Yadav, Sumit ^{10, 11}, Haynes, Laura ^{1, 5}, Kirkland, James L. ^{4, 9, 12}, Ikeno, Yuji ^{7, 13}, Xu, Ming ^{1, 2, 15, ∗}

Source: In Cell Metabolism 6 August 2024 36(8):1795-1805

Cellular Senescence as a Targetable Risk Factor for Cardiovascular Diseases: Therapeutic Implications: JACC Family Series

Authors: Kumar, Manish, Yan, Pengyi, Kuchel, George A., Xu, Ming

Source: In JACC: Basic to Translational Science April 2024 9(4):522-534

Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease

Authors: Forman, Daniel E., Kuchel, George A., Newman, John C., Kirkland, James L., Volpi, Elena, Taffet, George E., Barzilai, Nir, Pandey, Ambarish, Kitzman, Dalane W., Libby, Peter, Ferrucci, Luigi

Source: Journal of the American College of Cardiology. 82(7):631-647

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100195168723.0x000001&indx=1&recIds=ETOCvdc_100195168723.0x000001

Challenges and opportunities for modeling aging and cancer

Authors: Anczuków, Olga, Airhart, Susie, Chuang, Jeffrey H., Coussens, Lisa M., Kuchel, George A., Korstanje, Ron, Li, Sheng, Lucido, Anna Lisa, McAllister, Sandra S., Politi, Katerina, Polyak, Kornelia, Ratliff, Timothy, Ren, Gary, Trowbridge, Jennifer J., Ucar, Duygu, Palucka, Karolina

Source: Cancer cell. 41(4):641-645

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188796740.0x000001&indx=1&recIds=ETOCvdc_100188796740.0x000001

The heterogeneity of cellular senescence: insights at the single-cell level

Authors: Cohn, Rachel L., Gasek, Nathan S., Kuchel, George A., Xu, Ming

Source: Trends in cell biology. 33(1):9-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179072897.0x000001&indx=1&recIds=ETOCvdc_100179072897.0x000001

Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop

Authors: Yu, Xiaoying, Lobo, Judith D., Sundermann, Erin, Baker, Darren J., Tracy, Russell P., Kuchel, George A., Stephenson, Kathryn E., Letendre, Scott L., Brew, Bruce, Cysique, Lucette A., Dale, Sannisha K., Wallen, Chelsie, Kunisaki, Ken M., Guaraldi, Giovanni, Milic, Jovana, Winston, Alan, Moore, David J., Margolick, Joseph B., Erlandson, Kristine M.

Source: AIDS research and human retroviruses. 39(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176154245.0x000001&indx=1&recIds=ETOCvdc_100176154245.0x000001

Life’s Essential 8: Optimizing Health in Older Adults

Authors: Kumar, Manish, Orkaby, Ariela, Tighe, Caitlan, Villareal, Dennis T., Billingsley, Hayley, Nanna, Michael G., Kwak, Min Ji, Rohant, Namit, Patel, Shreya, Goyal, Parag, Hummel, Scott, Al-Malouf, Christina, Kolimas, Amie, Krishnaswami, Ashok, Rich, Michael W., Kirkpatrick, James, Damluji, Abdulla A., Kuchel, George A., Forman, Daniel E., Alexander, Karen P.

Source: In JACC: Advances September 2023 2(7)

Resilience in older adults with cancer: A scoping literature review

Authors: George, Thomas, Shah, Farah, Tiwari, Abhay, Gutierrez, Eutiquio, Ji, Jingran, Kuchel, George A., Cohen, Harvey J., Sedrak, Mina S.

Source: In Journal of Geriatric Oncology January 2023 14(1)

Major depression and the biological hallmarks of aging

Authors: Lorenzo, Erica C., Kuchel, George A., Kuo, Chia-Ling, Moffitt, Terrie E., Diniz, Breno S.

Source: In Ageing Research Reviews January 2023 83

Extending human healthspan and longevity: a symposium report

Authors: DeVito, Loren M., Barzilai, Nir, Cuervo, Ana Maria, Niedernhofer, Laura J., Milman, Sofiya, Levine, Morgan, Promislow, Daniel, Ferrucci, Luigi, Kuchel, George A., Mannick, Joan, Justice, Jamie, Gonzales, Mitzi M., Kirkland, James L., Cohen, Pinchas, Campisi, Judith

Source: Annals of the New York Academy of Sciences. 1507(1):70-83

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139257807.0x000001&indx=1&recIds=ETOCvdc_100139257807.0x000001

Examining the Role of Nonsurgical Therapy in the Treatment of Geriatric Urinary Incontinence

Authors: Parker-Autry, Candace, Neiberg, Rebecca, Leng, X. Iris, Matthews, Catherine A., Dumoulin, Chantale, Kuchel, George, Kritchevsky, Stephen B.

Source: Obstetrics and gynecology. 140(2):243-251

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191860423.0x000001&indx=1&recIds=ETOCvdc_100191860423.0x000001

Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia

Authors: Sugden, Karen, Caspi, Avshalom, Elliott, Maxwell L., Bourassa, Kyle J., Chamarti, Kartik, Corcoran, David L., Hariri, Ahmad R., Houts, Renate M., Kothari, Meeraj, Kritchevsky, Stephen, Kuchel, George A., Mill, Jonathan S., Williams, Benjamin S., Belsky, Daniel W., Moffitt, Terrie E.

Source: Neurology. 99(13):e1402-e1413

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173021474.0x000001&indx=1&recIds=ETOCvdc_100173021474.0x000001

Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach

Authors: Masters, Mary C., Landay, Alan L., Robbins, Paul D., Tchkonia, Tamar, Kirkland, James L., Kuchel, George A., Niedernhofer, Laura J., Palella, Frank J.

Source: Journal of acquired immune deficiency syndromes. 89(1):S34-S46

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171303383.0x000001&indx=1&recIds=ETOCvdc_100171303383.0x000001

Cognitive Frailty is Associated With Elevated Proinflammatory Markers and a Higher Risk of Mortality

Authors: Diniz, Breno S., Lima-Costa, Maria Fernanda, Peixoto, Sérgio Viana, Firmo, Joselia O.A., Torres, Karen C.L., Martins-Filho, Olindo Assis, Teixeira-Carvalho, Andréa, Grady, James, Kuchel, George A., Castro-Costa, Erico

Source: American journal of geriatric psychiatry. 30(7):825-833

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164424214.0x000001&indx=1&recIds=ETOCvdc_100164424214.0x000001

Alzheimer's disease amyloidogenesis is linked to altered lower urinary tract physiology

Authors: Hardy, Cara C., Ramasamy, Ramalakshmi, Rosenberg, Dawn A., Kuchel, George A., Yan, Riqiang, Hu, Xiangyou, Smith, Phillip P.

Source: Neurourology and urodynamics. 41(6):1344-1354

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157867834.0x000001&indx=1&recIds=ETOCvdc_100157867834.0x000001

Increased Levels of Circulating Cell-Free mtDNA in the Plasma of Subjects With Late-Life Depression and Frailty: A Preliminary Study

Authors: Ampo, Emi, Mendes-Silva, Ana Paula, Goncalves, Vanessa, Bartley, Jenna M., Kuchel, George A., Diniz, Breno S.

Source: American journal of geriatric psychiatry. 30(3):332-337

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156178059.0x000001&indx=1&recIds=ETOCvdc_100156178059.0x000001

Expanded Recommendations for Use of Pneumococcal Conjugate Vaccines Among Adults Aged ≥50 Years: Recommendations of the Advisory Committee on Immunization Practices -- United States, 2024.

Authors: Miwako Kobayashi, Leidner, Andrew J., Gierke, Ryan, Wei Xing, Accorsi, Emma, Moro, Pedro, Kamboj, Mini, Kuchel, George A., Schechter, Robert, Loehr, Jamie, Cohen, Adam L.

Source: MMWR: Morbidity & Mortality Weekly Report; 1/9/2025, Vol. 74 Issue 1, p1-8, 8p

Subject Terms: PNEUMOCOCCAL vaccines, IMMUNIZATION, STREPTOCOCCAL diseases, ADULTS, DRUGS

Diagnostic Power of Serum Creatinine/Cystatin C Ratio for Identifying Low MRI-Muscle Volume and Low Grip Strength: Data From 9 731 to 149 707 UK Biobank Older Adults.

Authors: Kirk, Ben, Kuo, Chia-Ling, Liu, Peiran, Xiang, Meiruo, Zanker, Jesse, Prokopidis, Konstantinos, Sim, Marc, Fortinsky, Richard H, Kuchel, George A, Duque, Gustavo

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences; Jan2025, Vol. 80 Issue 1, p1-8, 8p

Subject Terms: CYSTATIN C, GRIP strength, LEAN body mass, OLDER people, BODY mass index

Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity

Authors: Wang, Lichao, Wang, Binsheng, Gasek, Nathan S., Zhou, Yueying, Cohn, Rachel L., Martin, Dominique E., Zuo, Wulin, Flynn, William F., Guo, Chun, Jellison, Evan R., Kim, Taewan, Prata, Larissa G.P. Langhi, Palmer, Allyson K., Li, Ming, Inman, Christina L., Barber, Lauren S., Al-Naggar, Iman M.A., Zhou, Yanjiao, Du, Wenqiang, Kshitiz, Kuchel, George A., Meves, Alexander, Tchkonia, Tamar, Kirkland, James L., Robson, Paul, Xu, Ming

Source: In Cell Metabolism 4 January 2022 34(1):75-89