Advances in medical devices using nanomaterials and nanotechnology: Innovation and regulatory science

Authors: Chubing Lin, Xin Huang, Yueguang Xue, Shasha Jiang, Chunying Chen, Ying Liu, Kuan Chen

Source: Bioactive Materials, Vol 48, Iss , Pp 353-369 (2025)

Subject Terms: Nanomaterials, Medical device, Regulatory science, Safety and efficiency evaluation, In vitro alternative, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X25000659; https://doaj.org/toc/2452-199X

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Soil quality improvement on Qinghai-Tibet Plateau induced by soil hydrothermal changes from 1980s to 2020s

Authors: Kuan Chen, Jingyao Suo, Xiaodong Song, Yiyao Liu, Xiang Xiang, Yingping Pan, Jiarui Wang, Liang Ren, Xiaodong Ge, Xia Xu, Xiuchen Wu, Lei Duan, Yongmei Huang

Source: Geoderma, Vol 455, Iss , Pp 117235- (2025)

Subject Terms: Climate change, Soil quality index, Alpine cushion vegetation, Nitrogen limitation, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0016706125000734; https://doaj.org/toc/1872-6259

Access URL: https://doaj.org/article/e0fab5edb4974e9093f8a7c2b5b0c669

Deep learning for multi-type infectious keratitis diagnosis: A nationwide, cross-sectional, multicenter study

Authors: Zhongwen Li, He Xie, Zhouqian Wang, Daoyuan Li, Kuan Chen, Xihang Zong, Wei Qiang, Feng Wen, Zhihong Deng, Limin Chen, Huiping Li, He Dong, Pengcheng Wu, Tao Sun, Yan Cheng, Yanning Yang, Jinsong Xue, Qinxiang Zheng, Jiewei Jiang, Wei Chen

Source: npj Digital Medicine, Vol 7, Iss 1, Pp 1-11 (2024)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2398-6352

Access URL: https://doaj.org/article/526b9b1555d345e98501c9f8edb6bf6b

An emerging terpolymeric nanoparticle pore former as an internal recrystallization inhibitor of celecoxib in controlled release amorphous solid dispersion beads: Experimental studies and molecular dynamics analysis

Authors: Jamie Anne Lugtu-Pe, Xuning Zhang, Sako Mirzaie, Hao Han R. Chang, Nour AL-Mousawi, Kuan Chen, Yongqiang Li, Anil Kane, Daniel Bar-Shalom, Xiao Yu Wu

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2669-2684 (2024)

Subject Terms: Controlled release amorphous solid dispersion, Poorly soluble drug, Internal recrystallization, Membrane-reservoir coated beads, Molecular dynamics simulation, Effect of pore formers, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383524001072; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/4955f5c4544143eda661e42ec109ad16

DeepMonitoring: a deep learning-based monitoring system for assessing the quality of cornea images captured by smartphones

Authors: Zhongwen Li, Lei Wang, Wei Qiang, Kuan Chen, Zhouqian Wang, Yi Zhang, He Xie, Shanjun Wu, Jiewei Jiang, Wei Chen

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Subject Terms: artificial intelligence, cornea image, deep learning, quality, smartphone, Biology (General), QH301-705.5

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Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1447067/full; https://doaj.org/toc/2296-634X

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Recombinant FOXN1 fusion protein increases T cell generation in old mice

Authors: Jin Zhao, Rong Hu, Kuan Chen Lai, Zhenzhen Zhang, Laijun Lai

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: FOXN1, thymus, thymic epithelial cells, T cell generation, old mice, Immunologic diseases. Allergy, RC581-607

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Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423488/full; https://doaj.org/toc/1664-3224

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Characterization of two pterocarpan glycosyltransferases in Astragalus membranaceus and their application in whole-cell biocatalysis

Authors: Bai-Han Gao, Meng Zhang, Kuan Chen, Lin-Lin Wang, Ming-Ju Yao, Hong-Ye Li, Ming Xiong, Yu-Xi Huang, Yang Zhang, Quan-Li Liu, Juan Guo, Min Ye, Xue Qiao

Source: Medicinal Plant Biology, Vol 3, Iss 1, Pp 1-6 (2024)

Subject Terms: astragalus membranaceus, whole-cell biocatalysis, pterocarpan glycosyltransferases, Biology (General), QH301-705.5, Plant ecology, QK900-989

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Relation: https://doaj.org/toc/2835-6969

Access URL: https://doaj.org/article/6c1b69901f7c484db2bb80e91132dbb6

Racial and Socioeconomic Equity of Tecovirimat Treatment during the 2022 Mpox Emergency, New York, New York, USA

Authors: Maura K. Lash, Ned H. Latham, Pui Ying Chan, Mary M.K. Foote, Elizabeth A. Garcia, Matthew F. Silverstein, Marcia Wong, Mark Alexander, Karen A. Alroy, Lovedeep Bajaj, Kuan Chen, James Steele Howard, Lucretia E. Jones, Ellen H. Lee, Julian L. Watkins, Tristan D. McPherson

Source: Emerging Infectious Diseases, Vol 29, Iss 11, Pp 2353-2357 (2023)

Subject Terms: mpox, health equity, racism, tecovirimat, emergencies, sexually transmitted infections, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/29/11/23-0814_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

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Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants

Authors: Hao-Tian Wang, Zi-Long Wang, Kuan Chen, Ming-Ju Yao, Meng Zhang, Rong-Shen Wang, Jia-He Zhang, Hans Ågren, Fu-Dong Li, Junhao Li, Xue Qiao, Min Ye

Source: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7f3471b02bd948039766a1ff9037b182

Characterization and structure-based protein engineering of a regiospecific saponin acetyltransferase from Astragalus membranaceus

Authors: Linlin Wang, Zhihui Jiang, Jiahe Zhang, Kuan Chen, Meng Zhang, Zilong Wang, Binju Wang, Min Ye, Xue Qiao

Source: Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)

Subject Terms: Science

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Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ff52c7263f8141f18abb2b184e6aa97a

A highly selective C-rhamnosyltransferase from Viola tricolor and insights into its mechanisms

Authors: Bo-Yun Han, Zi-Long Wang, Junhao Li, Qing Jin, Hao-Tian Wang, Kuan Chen, Yang Yi, Hans Ågren, Xue Qiao, Min Ye

Source: Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3535-3544 (2023)

Subject Terms: Flavonoid C-glycoside, C-rhamnosyltransferase, Biosynthesis, Catalytic mechanisms, Sugar donor selectivity, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S2211383523001582; https://doaj.org/toc/2211-3835

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Identification of oxidosqualene cyclases associated with saponin biosynthesis from Astragalus membranaceus reveals a conserved motif important for catalytic function

Authors: Kuan Chen, Meng Zhang, Lulu Xu, Yang Yi, Linlin Wang, Haotian Wang, Zilong Wang, Jiangtao Xing, Pi Li, Xiaohui Zhang, Xiaomeng Shi, Min Ye, Anne Osbourn, Xue Qiao

Source: Journal of Advanced Research, Vol 43, Iss , Pp 247-257 (2023)

Subject Terms: Astragalus membranaceus, Oxidosqualene cyclase (OSC), β-Amyrin, Cycloartenol, Biosynthesis, Conserved motif, Medicine (General), R5-920, Science (General), Q1-390

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Relation: http://www.sciencedirect.com/science/article/pii/S2090123222000765; https://doaj.org/toc/2090-1232

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Ultra-fast triplet-triplet-annihilation-mediated high-lying reverse intersystem crossing triggered by participation of nπ*-featured excited states

Authors: Yanju Luo, Kai Zhang, Zhenming Ding, Ping Chen, Xiaomei Peng, Yihuan Zhao, Kuan Chen, Chuan Li, Xujun Zheng, Yan Huang, Xuemei Pu, Yu Liu, Shi-Jian Su, Xiandeng Hou, Zhiyun Lu

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

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Relation: https://doaj.org/toc/2041-1723

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MECG-E: Mamba-based ECG Enhancer for Baseline Wander Removal

Authors: Hung, Kuo-Hsuan, Wang, Kuan-Chen, Liu, Kai-Chun, Chen, Wei-Lun, Lu, Xugang, Tsao, Yu, Lin, Chii-Wann

Source: 2024 IEEE International Conference on Big Data (BigData) Big Data (BigData), 2024 IEEE International Conference on. :6469-6475 Dec, 2024

Relation: 2024 IEEE International Conference on Big Data (BigData)

MRI-based radiomics analysis improves preoperative diagnostic performance for the depth of stromal invasion in patients with early stage cervical cancer

Authors: Jing Ren, Yuan Li, Jun-Jun Yang, Jia Zhao, Yang Xiang, Chen Xia, Ying Cao, Bo Chen, Hui Guan, Ya-Fei Qi, Wen Tang, Kuan Chen, Yong-Lan He, Zheng-Yu Jin, Hua-Dan Xue

Source: Insights into Imaging, Vol 13, Iss 1, Pp 1-11 (2022)

Subject Terms: Cervical cancer, Stromal invasion, Magnetic resonance imaging, Radiomics, Risk factor, Medical physics. Medical radiology. Nuclear medicine, R895-920

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Relation: https://doaj.org/toc/1869-4101

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Perturbative Fourier Ptychographic Microscopy for Fast Quantitative Phase Imaging

Authors: Zach, Martin, Shen, Kuan-Chen, Cao, Ruiming, Unser, Michael, Waller, Laura, Dong, Jonathan

Subject Terms: Physics - Optics

Access URL: http://arxiv.org/abs/2501.07308

Bridging the Gap: Integrating Pre-Trained Speech Enhancement and Recognition Models for Robust Speech Recognition

Authors: Wang, Kuan-Chen, Li, You-Jin, Chen, Wei-Lun, Chen, Yu-Wen, Wang, Yi-Ching, Yeh, Ping-Cheng, Zhang, Chao, Tsao, Yu

Source: 2024 32nd European Signal Processing Conference (EUSIPCO) European Signal Processing Conference (EUSIPCO), 2024 32nd. :426-430 Aug, 2024

Relation: 2024 32nd European Signal Processing Conference (EUSIPCO)

A Non-Intrusive Neural Quality Assessment Model for Surface Electromyography Signals

Authors: Lee, Cho-Yuan, Wang, Kuan-Chen, Liu, Kai-Chun, Wang, Yu-Te, Lu, Xugang, Yeh, Ping-Cheng, Tsao, Yu

Source: 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Engineering in Medicine and Biology Society (EMBC), 2024 46th Annual International Conference of the IEEE. :1-5 Jul, 2024

Relation: 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Training nurses to perform water swallow test with use of standardised patients

Authors: Melissa Su Yi Yong, Xing Tong Yong, Olga Hillary Li Chew, Kuan Chen Zenne T’ng

Source: The Asia Pacific Scholar, Vol 6, Iss 3, Pp 91-94 (2021)

Subject Terms: water swallow test, standardised patients, train-the-trainer, dysphagia screening, Education (General), L7-991, Medicine (General), R5-920

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Relation: https://medicine.nus.edu.sg/taps/training-nurses-to-perform-water-swallow-test-with-use-of-standardised-patients/; https://doaj.org/toc/2424-9335; https://doaj.org/toc/2424-9270

Access URL: https://doaj.org/article/dec90d1dff6048f79574a102c2717892

Preventing corneal blindness caused by keratitis using artificial intelligence

Authors: Zhongwen Li, Jiewei Jiang, Kuan Chen, Qianqian Chen, Qinxiang Zheng, Xiaotian Liu, Hongfei Weng, Shanjun Wu, Wei Chen

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9c6058a1941f4c64be7df068856dd647