An immunostimulatory liponanogel reveals immune activation-enhanced drug delivery and therapeutic efficacy in cancer

Authors: Li, Xinyan, Wu, Chengcheng, Li, Junyao, Yu, Jinchao, Yang, Xiuxiu, Yu, Lvshan, Wang, Chaoyu, Kuai, Rui

Source: In Journal of Controlled Release December 2024 376:167-183

Systematic evaluation of the effect of different apolipoprotein A-I mimetic peptides on the performance of synthetic high-density lipoproteins in vitro and in vivo

Authors: Yuan, Wenmin, Ernst, Kelsey, Kuai, Rui, Morin, Emily E., Yu, Minzhi, Sviridov, Denis O., Tang, Jie, Mei, Ling, Li, Dan, Ackermann, Rose, Remaley, Alan T., Schwendeman, Anna

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine February 2023 48

Synthetic high-density lipoproteins delivering liver X receptor agonist prevent atherogenesis by enhancing reverse cholesterol transport

Authors: Yuan, Wenmin, Yu, Bilian, Yu, Minzhi, Kuai, Rui, Morin, Emily E., Wang, Huilun, Hu, Die, Zhang, Jifeng, Moon, James J., Chen, Y. Eugene, Guo, Yanhong, Schwendeman, Anna

Source: In Journal of Controlled Release 10 January 2021 329:361-371

Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Containing Cyclic Guanosine Monophosphate–Adenosine Monophosphate Eliminate Established Tumors.

Authors: Yu, Jinchao, Li, Xinyan, Li, Junyao, Sun, Nan, Cheng, Peng, Huang, Jiayi, Li, Sai, Kuai, Rui

Source: ACS Nano; 10/29/2024, Vol. 18 Issue 43, p29942-29955, 14p

Clathrin light chain‐conjugated drug delivery for cancer

Authors: Jung, Sungwook, Jiang, Liwei, Zhao, Jing, Shultz, Leonard D., Greiner, Dale L., Bae, Munhyung, Li, Xiaofei, Ordikhani, Farideh, Kuai, Rui, Joseph, John, Kasinath, Vivek, Elmaleh, David R., Abdi, Reza

Source: Bioengineering & translational medicine. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171056765.0x000001&indx=1&recIds=ETOCvdc_100171056765.0x000001

Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer

Authors: Wang, Ton, Subramanian, Chitra, Yu, Minzhi, White, Peter T., Kuai, Rui, Sanchez, Jaquelyn, Moon, James J., Timmermann, Barbara N., Schwendeman, Anna, Cohen, Mark S.

Source: In Surgery December 2019 166(6):1168-1175

Tuning the fluidity and protein corona of ultrasound-responsive liposomal nanovaccines to program T cell immunity in mice.

Authors: He, Jia, Wang, Chaoyu, Fang, Xiao, Li, Junyao, Shen, Xueying, Zhang, Junxia, Peng, Cheng, Li, Hongjian, Li, Sai, Karp, Jeffrey M., Kuai, Rui

Source: Nature Communications; 9/16/2024, Vol. 15 Issue 1, p1-15, 15p

Subject Terms: CANCER vaccines, INTRAVENOUS injections, CERVICAL cancer, IMMUNE response, SPLEEN, T cells

PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy

Authors: Ochyl, Lukasz J., Bazzill, Joseph D., Park, Charles, Xu, Yao, Kuai, Rui, Moon, James J.

Source: In Biomaterials November 2018 182:157-166

Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy

Authors: Kuai, Rui, Sun, Xiaoqi, Yuan, Wenmin, Ochyl, Lukasz J., Xu, Yao, Hassani Najafabadi, Alireza, Scheetz, Lindsay, Yu, Min-Zhi, Balwani, Ishina, Schwendeman, Anna, Moon, James J.

Source: In Journal of Controlled Release 28 July 2018 282:131-139

Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal

Authors: Subramanian, Chitra, White, Peter T., Kuai, Rui, Kalidindi, Avinaash, Castle, Valerie P., Moon, James J., Timmermann, Barbara N., Schwendeman, Anna, Cohen, Mark S.

Source: In Surgery July 2018 164(1):165-172

High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia

Authors: Park, Hyun-Ji, Kuai, Rui, Jeon, Eun Je, Seo, Yoojin, Jung, Youngmee, Moon, James J., Schwendeman, Anna, Cho, Seung-Woo

Source: In Biomaterials April 2018 161:69-80

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme

Authors: Kadiyala, Padma, Li, Dan, Nuñez, Fernando M., Altshuler, David, Doherty, Robert, Kuai, Rui, Yu, Minzhi, Kamran, Neha, Edwards, Marta, Moon, James J.

Source: ACS nano. 13(2):1365-1384

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619445129&indx=1&recIds=ETOCRN619445129

Effect of size and pegylation of liposomes and peptide-based synthetic lipoproteins on tumor targeting

Authors: Tang, Jie, Kuai, Rui, Yuan, Wenmin, Drake, Lindsey, Moon, James J., Schwendeman, Anna

Source: In Nanomedicine: Nanotechnology, Biology, and Medicine August 2017 13(6):1869-1878

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

Authors: Nam, Jutaek, Son, Sejin, Ochyl, Lukasz, Kuai, Rui, Schwendeman, Anna, Moon, James

Source: Nature communications. 9(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127966066.0x000001&indx=1&recIds=ETOCvdc_100127966066.0x000001

Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy

Authors: Kuai, Rui, Sun, Xiaoqi, Yuan, Wenmin, Xu, Yao, Schwendeman, Anna, Moon, James J.

Source: Bioconjugate chemistry. 29(3):771-775

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631360759&indx=1&recIds=ETOCRN631360759

Synthetic high-density lipoprotein nanoparticles: A novel therapeutic strategy for adrenocortical carcinomas

Authors: Subramanian, Chitra, Kuai, Rui, Zhu, Qing, White, Peter, Moon, James J., Schwendeman, Anna, Cohen, Mark S.

Source: In Surgery January 2016 159(1):284-295

High-Density Lipoproteins: Nature's Multifunctional Nanoparticles

Authors: Kuai, Rui, Li, Dan, Chen, Y. Eugene, Moon, James J., Schwendeman, Anna

Source: ACS nano. 10(3):3015-3041

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605634987&indx=1&recIds=ETOCRN605634987

RalA exerts an inhibitory effect on IL-1β/IL-18 secretion by blocking NLRP3 inflammasome activation in levornidazole-treated human THP-1 macrophages

Authors: Wang, Xingqi, Gou, Lingshan, Gao, Yuzhi, Huang, Yuqing, Kuai, Rui, Li, Yu, Wang, Yujing, Chen, Yanhong, Li, Jun, Cheng, Chao, Feng, Zhaojun, Wu, Xuefeng, Yao, Ruiqin

Source: International immunopharmacology. 88

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110047585.0x000001&indx=1&recIds=ETOCvdc_100110047585.0x000001

Robust Anti‐Tumor T Cell Response with Efficient Intratumoral Infiltration by Nanodisc Cancer Immunotherapy

Authors: Kuai, Rui, Singh, Priti B., Sun, Xiaoqi, Xu, Cheng, Hassani Najafabadi, Alireza, Scheetz, Lindsay, Yuan, Wenmin, Xu, Yao, Hong, Hao, Keskin, Derin B., Wu, Catherine J., Jain, Renu, Schwendeman, Anna, Moon, James J.

Source: Advanced therapeutics. 3(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107961577.0x000001&indx=1&recIds=ETOCvdc_100107961577.0x000001

Comparison of four different peptides to enhance accumulation of liposomes into the brain

Authors: Qin, Yao, Zhang, Qianyu, Chen, Huali, Yuan, Wenmin, Kuai, Rui, Xie, Fulan, Zhang, Li, Wang, Xiaoxiao, Zhang, Zhirong, Liu, Ji, He, Qin

Source: Journal of drug targeting. 20(3):235-245

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105416507.0x000001&indx=1&recIds=ETOCvdc_100105416507.0x000001