Synthesis and evaluation of fluorinated tetrahydrocarbazoles as probes in NMR based binding assay of the E. coli β sliding clamp

Authors: Olsen, Cecilie Elisabeth ^a, Simonsen, Signe ^{b, c}, Merugu, Srinivas Reddy ^a, Eigner, Vaclav ^d, Aachmann, Finn L. ^e, Kragelund, Birthe B. ^{b, c}, Sundby, Eirik ^f, Hoff, Bård Helge ^{a, ⁎}

Source: In Bioorganic & Medicinal Chemistry 1 May 2025 122

On the use of dioxane as reference for determination of the hydrodynamic radius by NMR spectroscopy

Authors: Tranchant, Emil E., Pesce, Francesco, Jacobsen, Nina L., Fernandes, Catarina B., Kragelund, Birthe B., Lindorff-Larsen, Kresten

Source: In Biophysical Journal 5 November 2024 123(21):3759-3770

Effects of ligand binding on the energy landscape of acyl-CoA-binding protein

Authors: Sonar, Punam, Bellucci, Luca, Mossa, Alessandro, Heidarsson, Pétur O., Kragelund, Birthe B., Cecconi, Ciro

Source: Biophys. J. 119 (2020) 1821-1832

Subject Terms: Physics - Biological Physics, Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2111.13873

Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue

Authors: Ardenkjær-Skinnerup, Jacob, Saar, Daniel, Christiansen, Sofie, Svingen, Terje, Hadrup, Niels, Brown, Kristy A., Emanuelli, Brice, Kragelund, Birthe B., Ravn-Haren, Gitte, Vogel, Ulla

Source: In Biochemistry and Biophysics Reports July 2024 38

On the potential of machine learning to examine the relationship between sequence, structure, dynamics and function of intrinsically disordered proteins

Authors: Lindorff-Larsen, Kresten, Kragelund, Birthe B.

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2106.00855

Myotubularin-related-protein-7 inhibits mutant (G12V) K-RAS by direct interaction

Authors: Weidner, Philip, Saar, Daniel, Söhn, Michaela, Schroeder, Torsten, Yu, Yanxiong, Zöllner, Frank G., Ponelies, Norbert, Zhou, Xiaobo, Zwicky, André, Rohrbacher, Florian N., Pattabiraman, Vijaya R., Tanriver, Matthias, Bauer, Alexander, Ahmed, Hazem, Ametamey, Simon M., Riffel, Philipp, Seger, Rony, Bode, Jeffrey W., Wade, Rebecca C., Ebert, Matthias P.A., Kragelund, Birthe B., Burgermeister, Elke

Source: In Cancer Letters 28 April 2024 588

PPARγ antagonists induce aromatase transcription in adipose tissue cultures

Authors: Ardenkjær-Skinnerup, Jacob, Saar, Daniel, Petersen, Patricia S.S., Pedersen, Mikael, Svingen, Terje, Kragelund, Birthe B., Hadrup, Niels, Ravn-Haren, Gitte, Emanuelli, Brice, Brown, Kristy A., Vogel, Ulla

Source: In Biochemical Pharmacology April 2024 222

Realizing integration in structural biology: The 2022 ISBUC Annual Meeting

Authors: Kragelund, Birthe B., Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen L., Gajhede, Michael, Christensen, Caspar Elo, Holt, Lucy

Source: STRUCTURE -CAMBRIDGE MASSACHUSETTS. 31(7):747-754

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194012848.0x000001&indx=1&recIds=ETOCvdc_100194012848.0x000001

Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

Authors: Pesce, Francesco, Newcombe, Estella A., Seiffert, Pernille, Tranchant, Emil E., Olsen, Johan G., Grace, Christy R., Kragelund, Birthe B., Lindorff-Larsen, Kresten

Source: Biophysical journal. 122(2):310-321

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188889959.0x000001&indx=1&recIds=ETOCvdc_100188889959.0x000001

Modeling of flexible membrane-bound biomolecular complexes for solution small-angle scattering

Authors: Barclay, Abigail, Kragelund, Birthe B., Arleth, Lise, Pedersen, Martin Cramer

Source: Journal of colloid and interface science. 635:611-621

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185821287.0x000001&indx=1&recIds=ETOCvdc_100185821287.0x000001

Conformational entropy in molecular recognition of intrinsically disordered proteins

Authors: Skriver, Karen, Theisen, Frederik Friis, Kragelund, Birthe B.

Source: In Current Opinion in Structural Biology December 2023 83

Structural characterization of human tryptophan hydroxylase 2 reveals that L-Phe is superior to L-Trp as the regulatory domain ligand

Authors: Vedel, Ida M., Prestel, Andreas, Zhang, Zhenwei, Skawinska, Natalia T., Stark, Holger, Harris, Pernille, Kragelund, Birthe B., Peters, Günther H.J.

Source: In Structure 1 June 2023 31(6):689-699

Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation

Authors: Chhabra, Yash, Seiffert, Pernille, Gormal, Rachel S., Vullings, Manon, Lee, Christine Mei Mei, Wallis, Tristan P., Dehkhoda, Farhad, Indrakumar, Sowmya, Jacobsen, Nina L., Lindorff-Larsen, Kresten, Durisic, Nela, Waters, Michael J., Meunier, Frédéric A., Kragelund, Birthe B., Brooks, Andrew J.

Source: In Cell Reports 30 May 2023 42(5)

The denatured state of HIV‐1 protease under native conditions

Authors: Rösner, Heike I., Caldarini, Martina, Potel, Gregory, Malmodin, Daniel, Vanoni, Maria A., Aliverti, Alessandro, Broglia, Ricardo A., Kragelund, Birthe B., Tiana, Guido

Source: Proteins. 90(1):96-109

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100147555088.0x000001&indx=1&recIds=ETOCvdc_100147555088.0x000001

Structure, dynamics, and stability of the globular domain of human linker histone H1.0 and the role of positive charges

Authors: Martinsen, Jacob H., Saar, Daniel, Fernandes, Catarina B., Schuler, Benjamin, Bugge, Katrine, Kragelund, Birthe B.

Source: Protein science. 31(4):918-932

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144239506.0x000001&indx=1&recIds=ETOCvdc_100144239506.0x000001

Allovalent scavenging of activation domains in the transcription factor ANAC013 gears transcriptional regulation.

Authors: Delaforge, Elise, Due, Amanda D, Theisen, Frederik Friis, Morffy, Nicolas, O'Shea, Charlotte, Blackledge, Martin, Strader, Lucia C, Skriver, Karen, Kragelund, Birthe B

Source: Nucleic Acids Research; 2/28/2025, Vol. 53 Issue 4, p1-15, 15p

Proline cis/trans Conformational Selection Controls 14–3–3 Binding.

Authors: Theisen, Frederik F., Prestel, Andreas, Jacobsen, Nina L., Nyhegn-Eriksen, Oline K., Olsen, Johan G., Kragelund, Birthe B.

Source: Journal of the American Chemical Society; 2/19/2025, Vol. 147 Issue 7, p5714-5724, 11p

αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes

Authors: Friis Theisen, Frederik, Salladini, Edoardo, Davidsen, Rikke, Jo Rasmussen, Christina, Staby, Lasse, Kragelund, Birthe B., Skriver, Karen

Source: In Journal of Biological Chemistry June 2022 298(6)

Flanking Disorder of the Folded αα-Hub Domain from Radical Induced Cell Death1 Affects Transcription Factor Binding by Ensemble Redistribution

Authors: Staby, Lasse, Due, Amanda D., Kunze, Micha Ben Achim, Jørgensen, Maria Louise Mønster, Skriver, Karen, Kragelund, Birthe B.

Source: In Journal of Molecular Biology 3 December 2021 433(24)

Importance of an N-terminal structural switch in the distinction between small RNA-bound and free ARGONAUTE

Authors: Bressendorff, Simon, Sjøgaard, Ida Marie Zobbe, Prestel, Andreas, Voutsinos, Vasileios, Jansson, Martin D., Ménard, Patrice, Lund, Anders H., Hartmann-Petersen, Rasmus, Kragelund, Birthe B., Poulsen, Christian, Brodersen, Peter

Source: Nature Structural and Molecular Biology; 20250101, Issue: Preprints p1-14, 14p