Activating transcription factor 6 protects against endothelial barrier dysfunction

Authors: Kubra, Khadeja-Tul, Akhter, Mohammad S., Saini, Yogesh, Kousoulas, Konstantin G., Barabutis, Nektarios

Source: In Cellular Signalling November 2022 99

Cross protective efficacy of the Non-Neurotropic live attenuated herpes simplex virus type 1 vaccine VC-2 is enhanced by intradermal vaccination and deletion of glycoprotein G

Authors: Stanfield, Brent A., Bravo, Fernando J., Dixon, David A., Chouljenko, Vladimir N., Kousoulas, Konstantin G., Bernstein, David I.

Source: Vaccine. 40(42):6093-6099

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178368391.0x000001&indx=1&recIds=ETOCvdc_100178368391.0x000001

The Novel Oncolytic Herpes Simplex Virus Type‐1 (HSV‐1) Vaccine Strain VC2 Constitutively Expressing GM‐CSF Causes Increased Intratumoral T Cell Infiltration and Inhibition of Tumor Metastasis in the 4T1/Balb/c Mouse Model of Stage Four Breast Cancer

Authors: Nabi, Rafiq, Chouljenko, Vladimir N., Musarrat, Farhana, Davis, Megan E., Mohan, Harikrishnan, Ghavimi, Reza, Stanfield, Brent, Dutta, Ojasvi, Kousoulas, Konstantin G.

Source: Journal of Medical Virology; Feb2025, Vol. 97 Issue 2, p1-11, 11p

Development of a reliable bovine neuronal cell culture system and labeled recombinant bovine herpesvirus type-1 for studying virus-host cell interactions

Authors: Rudd, Jared S., Musarrat, Farhana, Kousoulas, Konstantin G. ^*

Source: In Virus Research February 2021 293

Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers

Authors: Roy, Tithi, Boateng, Samuel T., Banang-Mbeumi, Sergette, Singh, Pankaj K., Basnet, Pratik, Chamcheu, Roxane-Cherille N., Ladu, Federico, Chauvin, Isabel, Spiegelman, Vladimir S., Hill, Ronald A., Kousoulas, Konstantin G., Nagalo, Bolni Marius, Walker, Anthony L., Fotie, Jean, Murru, Siva, Sechi, Mario, Chamcheu, Jean Christopher

Source: In Bioorganic Chemistry February 2021 107

A Herpes Simplex Virus Type‐1‐Derived Influenza Vaccine Induces Balanced Adaptive Immune Responses and Protects Mice From Lethal Influenza Virus Challenge.

Authors: Rider, Paul J. F., Dulin, Harrison, Uche, Ifeanyi K., McGee, Michael C., Huang, Weishan, Kousoulas, Konstantin G., Hai, Rong

Source: Journal of Medical Virology; Nov2024, Vol. 96 Issue 11, p1-11, 11p

Subject Terms: HUMAN herpesvirus 1, INFLUENZA vaccines, FLU vaccine efficacy, RECOMBINANT viruses, INFLUENZA viruses

The anti‐HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV‐2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID‐19 infections

Authors: Musarrat, Farhana, Chouljenko, Vladimir, Dahal, Achyut, Nabi, Rafiq, Chouljenko, Tamara, Jois, Seetharama D., Kousoulas, Konstantin G.

Source: Journal of medical virology. 92(10):2087-2095

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108179269.0x000001&indx=1&recIds=ETOCvdc_100108179269.0x000001

Genomic analysis for virulence determinants in feline herpesvirus type-1 isolates

Authors: Lewin, Andrew C., Coghill, Lyndon M., McLellan, Gillian J., Bentley, Ellison, Kousoulas, Konstantin G.

Source: VIRUS GENES. 56(1):49-57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127787633.0x000001&indx=1&recIds=ETOCvdc_100127787633.0x000001

The HSV-1 live attenuated VC2 vaccine provides protection against HSV-2 genital infection in the guinea pig model of genital herpes

Authors: Bernstein, David I., Pullum, Derek A., Cardin, Rhonda D., Bravo, Fernando J., Dixon, David A., Kousoulas, Konstantin G.

Source: Vaccine. 37(1):61-68

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100072516721.0x000001&indx=1&recIds=ETOCvdc_100072516721.0x000001

Anti-viral Immunity in the Tumor Microenvironment: Implications for the Rational Design of Herpes Simplex Virus Type 1 Oncolytic Virotherapy

Authors: Rider, Paul J. F., Uche, Ifeanyi K., Sweeny, Larissa, Kousoulas, Konstantin G.

Source: Current clinical microbiology reports. 6(4):193-199

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130483317.0x000001&indx=1&recIds=ETOCvdc_100130483317.0x000001

Peptides and peptidomimetics as therapeutic agents for Covid‐19

Authors: Dahal, Achyut, Sonju, Jafrin Jobayer, Kousoulas, Konstantin G., Jois, Seetharama D.

Source: Peptide science. 114(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139316362.0x000001&indx=1&recIds=ETOCvdc_100139316362.0x000001

Nonpathologic Infection of Macaques by an Attenuated Mycobacterial Vaccine Is Not Reactivated in the Setting of HIV Co-Infection

Authors: Foreman, Taylor W., Veatch, Ashley V., LoBato, Denae N., Didier, Peter J., Doyle-Meyers, Lara A., Russell-Lodrigue, Kasi E., Lackner, Andrew A., Kousoulas, Konstantin G., Khader, Shabaana A., Kaushal, Deepak, Mehra, Smriti

Source: In The American Journal of Pathology December 2017 187(12):2811-2820

Targeting Cancers with oHSV-Based Oncolytic Viral Immunotherapy.

Authors: Nasar, Rakin Tammam, Uche, Ifeanyi Kingsley, Kousoulas, Konstantin G.

Source: Current Issues in Molecular Biology; Jun2024, Vol. 46 Issue 6, p5582-5594, 13p

Guinea pig herpes like virus is a gamma herpesvirus.

Authors: Stanfield, Brent A., Ruiz, Emmanuelle, Chouljenko, Vladimir N., Kousoulas, Konstantin G.

Source: Virus Genes; Apr2024, Vol. 60 Issue 2, p148-158, 11p

Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies

Authors: Stanfield, Brent A., Pahar, Bapi, Chouljenko, Vladimir N., Veazey, Ronald, Kousoulas, Konstantin G.

Source: In Vaccine 23 January 2017 35(4):536-543

Production of a Rabbit Anti-Cockatiel Immunoglobulin G and Characterization of Its Cross-Reactivities with Immunoglobulin G of Other Psittacine Species

Authors: Baghian, Abolghasem, Reyes, Cassandra Veronica, Mendoza, Acacia, Tully,, Thomas N., Kousoulas, Konstantin G.

Source: Avian Diseases, 1999 Jan 01. 43(1), 48-54.

Access URL: https://www.jstor.org/stable/1592761

Proximity ligation assay to study protein–protein interactions of proteins on two different cells

Authors: Sable, Rushikesh, Jambunathan, Nithya, Singh, Sitanshu, Pallerla, Sandeep, Kousoulas, Konstantin G, Jois, Seetharama

Source: Biotechniques. 65(3):149-157

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130127461.0x000001&indx=1&recIds=ETOCvdc_100130127461.0x000001

First Impressions—the Potential of Altering Initial Host-Virus Interactions for Rational Design of Herpesvirus Vaccine Vectors

Authors: Rider, Paul J. F., Musarrat, Farhana, Nabi, Rafiq, Naidu, Shan, Kousoulas, Konstantin G.

Source: Current clinical microbiology reports. 5(1):55-65

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130485490.0x000001&indx=1&recIds=ETOCvdc_100130485490.0x000001

Bovine herpesvirus type-1 glycoprotein K (gK) interacts with UL20 and is required for infectious virus production

Authors: Haque, Muzammel, Stanfield, Brent, Kousoulas, Konstantin G.

Source: In Virology December 2016 499:156-164

Th2 and Th17‐associated immunopathology following SARS‐CoV‐2 breakthrough infection in Spike‐vaccinated ACE2‐humanized mice.

Authors: Zhang, Tianyi, Magazine, Nicholas, McGee, Michael C., Carossino, Mariano, Veggiani, Gianluca, Kousoulas, Konstantin G., August, Avery, Huang, Weishan

Source: Journal of Medical Virology; Jan2024, Vol. 96 Issue 1, p1-12, 12p

Subject Terms: BREAKTHROUGH infections, PEPTIDE vaccines, IMMUNOPATHOLOGY, SARS-CoV-2, COVID-19 vaccines, CARDIAC amyloidosis