Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells

Authors: Doi, Tomomitsu, Hojo, Hironori, Ohba, Shinsuke, Obayashi, Kunie, Endo, Motoyoshi, Ishizaki, Toshimasa, Katoh, Akira, Kouji, Hiroyuki

Source: In Heliyon February 2022 8(2)

Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α

Authors: Shimizu, Takahiro, Takahashi, Norihito, Huber, Vincent J., Asawa, Yasunobu, Ueda, Hiroki, Yoshimori, Atsushi, Muramatsu, Yukiko, Seimiya, Hiroyuki, Kouji, Hiroyuki, Nakamura, Hiroyuki, Oguri, Hiroki

Source: In Bioorganic & Medicinal Chemistry 15 January 2021 30

Synthesis of Three‐Dimensional (Di)Azatricyclododecene Scaffold and Its Application to Peptidomimetics

Authors: Umedera, Kohei, Morita, Taiki, Yoshimori, Atsushi, Yamada, Kentaro, Katoh, Akira, Kouji, Hiroyuki, Nakamura, Hiroyuki

Source: Chemistry. 27(46):11888-11894

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127385281.0x000001&indx=1&recIds=ETOCvdc_100127385281.0x000001

DeepCubist: Molecular Generator for Designing Peptidomimetics based on Complex three-dimensional scaffolds.

Authors: Umedera, Kohei^1,2, Yoshimori, Atsushi³, Chen, Hengwei², Kouji, Hiroyuki⁴, Nakamura, Hiroyuki^1,5, hiro@res.titech.ac.jp, Bajorath, Jürgen², bajorath@bit.uni-bonn.de

Source: Journal of Computer-Aided Molecular Design; Feb2023, Vol. 37 Issue 2, p107-115, 9p

mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model

Authors: Kawase, Haruki, Ago, Yukio, Naito, Megumi, Higuchi, Momoko, Hara, Yuta, Hasebe, Shigeru, Tsukada, Shinji, Kasai, Atsushi, Nakazawa, Takanobu, Mishina, Tadashi, Kouji, Hiroyuki, Takuma, Kazuhiro, Hashimoto, Hitoshi

Source: In Pharmacology, Biochemistry and Behavior January 2019 176:1-5

The novel inhibitor PRI-724 for Wnt/β-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice

Authors: Okazaki, Hiroyasu, Sato, Seidai, Koyama, Kazuya, Morizumi, Shun, Abe, Shuichi, Azuma, Momoyo, Chen, Yajuan, Goto, Hisatsugu, Aono, Yoshinori, Ogawa, Hirohisa, Kagawa, Kozo, Nishimura, Haruka, Kawano, Hiroshi, Toyoda, Yuko, Uehara, Hisanori, Kouji, Hiroyuki, Nishioka, Yasuhiko

Source: Experimental lung research. 45(7):188-199

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105907919.0x000001&indx=1&recIds=ETOCvdc_100105907919.0x000001

Selective Inhibition of β-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis

Authors: Matsuda-Hirose, Haruna, Yamate, Tomoko, Goto, Mizuki, Katoh, Akira, Kouji, Hiroyuki, Yamamoto, Yuya, Sakai, Takashi, Uemura, Naoto, Kobayashi, Takashi, Hatano, Yutaka

Source: Annals of dermatology. 31(6):631-639

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622086187&indx=1&recIds=ETOCRN622086187

A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models

Authors: Ueda, Hiroshi, Kurita, Jun-ichi, Neyama, Hiroyuki, Hirao, Yuuka, Kouji, Hiroyuki, Mishina, Tadashi, Kasai, Masaji, Nakano, Hirofumi, Yoshimori, Atsushi, Nishimura, Yoshifumi

Source: Bioorganic & medicinal chemistry letters. 27(20):4705-4709

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129143531.0x000001&indx=1&recIds=ETOCvdc_100129143531.0x000001

Alpha helix mimetics and methods relating thereto

Β-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis

Authors: Hirakawa, Tomoko, Nasu, Kaei, Miyabe, Saori, Kouji, Hiroyuki, Katoh, Akira, Uemura, Naoto, Narahara, Hisashi

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131393811.0x000001&indx=1&recIds=ETOCvdc_100131393811.0x000001

Identification of new agonists of urotensin-II from a cyclic peptide library

Authors: Odagami, Takenao, Tsuda, Yuko, Kogami, Yuji, Kouji, Hiroyuki, Okada, Yoshio

Source: In Bioorganic & Medicinal Chemistry 2009 17(18):6742-6747

Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions

COMPOUND CAPABLE OF BINDING TO NATURALLY OCCURRING DENATURED PROTEIN, AND METHOD FOR SCREENING FOR THE COMPOUND

ALPHA HELIX MIMETICS AND METHODS RELATING THERETO

ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER

ALPHA HELIX MIMETICS AND METHODS RELATING THERETO

A novel mRNA decay inhibitor abolishes pathophysiological cellular transition.

Authors: Kami, Daisuke, Ishizaki, Toshimasa, Taya, Toshihiko, Katoh, Akira, Kouji, Hiroyuki, Gojo, Satoshi

Source: Cell Death Discovery; 6/7/2022, Vol. 8 Issue 1, p1-9, 9p

Comprehensive exploration of chemical space using trisubstituted carboranes.

Authors: Asawa, Yasunobu, Hatsuzawa, Saki, Yoshimori, Atsushi, Yamada, Kentaro, Katoh, Akira, Kouji, Hiroyuki, Nakamura, Hiroyuki

Source: Scientific Reports; 12/16/2021, Vol. 11 Issue 1, p1-12, 12p

Subject Terms: CARBORANES, MOMENTS method (Statistics), RABIES virus, MOMENTS of inertia

N-substituted-phenylteraconimide compound, herbicidal composition, and method for the destruction of undesirable weeds

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