Ferroptosis in health and disease

Authors: Berndt, Carsten, Alborzinia, Hamed, Amen, Vera Skafar, Ayton, Scott, Barayeu, Uladzimir, Bartelt, Alexander, Bayir, Hülya, Bebber, Christina M., Birsoy, Kivanc, Böttcher, Jan P., Brabletz, Simone, Brabletz, Thomas, Brown, Ashley R., Brüne, Bernhard, Bulli, Giorgia, Bruneau, Alix, Chen, Quan, DeNicola, Gina M., Dick, Tobias P., Distéfano, Ayelén, Dixon, Scott J., Engler, Jan B., Esser-von Bieren, Julia, Fedorova, Maria, Friedmann Angeli, José Pedro, Friese, Manuel A., Fuhrmann, Dominic C., García-Sáez, Ana J., Garbowicz, Karolina, Götz, Magdalena, Gu, Wei, Hammerich, Linda, Hassannia, Behrouz, Jiang, Xuejun, Jeridi, Aicha, Kang, Yun Pyo, Kagan, Valerian E., Konrad, David B., Kotschi, Stefan, Lei, Peng, Le Tertre, Marlène, Lev, Sima, Liang, Deguang, Linkermann, Andreas, Lohr, Carolin, Lorenz, Svenja, Luedde, Tom, Methner, Axel, Michalke, Bernhard, Milton, Anna V., Min, Junxia, Mishima, Eikan, Müller, Sebastian, Motohashi, Hozumi, Muckenthaler, Martina U., Murakami, Shohei, Olzmann, James A., Pagnussat, Gabriela, Pan, Zijan, Papagiannakopoulos, Thales, Pedrera Puentes, Lohans, Pratt, Derek A., Proneth, Bettina, Ramsauer, Lukas, Rodriguez, Raphael, Saito, Yoshiro, Schmidt, Felix, Schmitt, Carina, Schulze, Almut, Schwab, Annemarie, Schwantes, Anna, Soula, Mariluz, Spitzlberger, Benedikt, Stockwell, Brent R., Thewes, Leonie, Thorn-Seshold, Oliver, Toyokuni, Shinya, Tonnus, Wulf, Trumpp, Andreas, Vandenabeele, Peter, Vanden Berghe, Tom, Venkataramani, Vivek, Vogel, Felix C.E., von Karstedt, Silvia, Wang, Fudi, Westermann, Frank, Wientjens, Chantal, Wilhelm, Christoph, Wölk, Michele, Wu, Katherine, Yang, Xin, Yu, Fan, Zou, Yilong, Conrad, Marcus

Source: In Redox Biology September 2024 75

NFE2L1-mediated proteasome function protects from ferroptosis

Authors: Kotschi, Stefan, Jung, Anna, Willemsen, Nienke, Ofoghi, Anahita, Proneth, Bettina, Conrad, Marcus, Bartelt, Alexander

Source: Molecular metabolism. 57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155900925.0x000001&indx=1&recIds=ETOCvdc_100155900925.0x000001

The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.

Authors: Giroud, Maude, Kotschi, Stefan, Kwon, Yun, Le Thuc, Ophélia, Hoffmann, Anne, Gil‐Lozano, Manuel, Karbiener, Michael, Higareda‐Almaraz, Juan Carlos, Khani, Sajjad, Tews, Daniel, Fischer‐Posovszky, Pamela, Sun, Wenfei, Dong, Hua, Ghosh, Adhideb, Wolfrum, Christian, Wabitsch, Martin, Virtanen, Kirsi A, Blüher, Matthias, Nielsen, Søren, Zeigerer, Anja

Source: EMBO Reports; 10/9/2023, Vol. 24 Issue 10, p1-19, 19p

Activating the NFE2L1-ubiquitin-proteasome system by DDI2 protects from ferroptosis

Authors: Ofoghi, Anahita, Kotschi, Stefan, Lemmer, Imke L., Haas, Daniel T., Willemsen, Nienke, Bayer, Batoul, Jung, Anna S., Möller, Sophie, Haberecht-Müller, Stefanie, Krüger, Elke, Krahmer, Natalie, Bartelt, Alexander

Source: Cell Death and Differentiation; 20240101, Issue: Preprints p1-8, 8p

Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.

Authors: Ziegler, Karin A.^1,2, Ahles, Andrea^1,2, Dueck, Anne^1,2, Esfandyari, Dena^1,2, Pichler, Pauline¹, Weber, Karolin¹, Kotschi, Stefan³, Bartelt, Alexander^2,3,4,5, Sinicina, Inga⁶, Graw, Matthias⁶, Leonhardt, Heinrich⁷, Weckbach, Ludwig T.^2,8,9, Massberg, Steffen^2,8, Schifferer, Martina^10,11, Simons, Mikael^10,11,12, Hoeher, Luciano¹³, Jie Luo^13,14, Ertürk, Ali^11,13,14, Schiattarella, Gabriele G.^15,16,17, Sassi, Yassine^18,19,20

Source: Science; 7/21/2023, Vol. 381 Issue 6655, p285-290, 6p, 4 Color Photographs

Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.

Authors: Sigmund, Anna M., Winkler, Markus, Engelmayer, Sophia, Kugelmann, Daniela, Egu, Desalegn T., Steinert, Letyfee S., Fuchs, Michael, Hiermair, Matthias, Radeva, Mariya Y., Bayerbach, Franziska C., Butz, Elisabeth, Kotschi, Stefan, Hudemann, Christoph, Hertl, Michael, Yeruva, Sunil, Schmidt, Enno, Yazdi, Amir S., Ghoreschi, Kamran, Vielmuth, Franziska, Waschke, Jens

Source: Nature Communications; 1/9/2023, Vol. 14 Issue 1, p1-17, 17p

Subject Terms: APREMILAST, PHOSPHODIESTERASE inhibitors, KERATINOCYTE differentiation, PEMPHIGUS, AUTOANTIBODIES, EPIDERMIS, KERATINOCYTES, PEMPHIGUS vulgaris

Role of Ubiquilins for Brown Adipocyte Proteostasis and Thermogenesis.

Authors: Muley, Carolin, Kotschi, Stefan, Bartelt, Alexander

Source: Frontiers in Endocrinology; 9/28/2021, Vol. 12, p1-9, 9p

Subject Terms: FAT cells, BODY temperature regulation, BROWN adipose tissue, GENE silencing, PROTEOLYSIS

HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.

Authors: Giroud, Maude, Tsokanos, Foivos-Filippos, Caratti, Giorgio, Kotschi, Stefan, Khani, Sajjad, Jouffe, Céline, Vogl, Elena S., Irmler, Martin, Glantschnig, Christina, Gil-Lozano, Manuel, Hass, Daniela, Khan, Asrar Ali, Garcia, Marcos Rios, Mattijssen, Frits, Maida, Adriano, Tews, Daniel, Fischer-Posovszky, Pamela, Feuchtinger, Annette, Virtanen, Kirsi A., Beckers, Johannes

Source: Diabetologia; Aug2021, Vol. 64 Issue 8, p1850-1865, 16p

Fire up the pyre: inosine thermogenic signaling for obesity therapy.

Authors: Willemsen, Nienke, Kotschi, Stefan, Bartelt, Alexander

Source: Signal Transduction & Targeted Therapy; 11/11/2022, Vol. 7 Issue 1, p1-2, 2p

Author Correction: Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.

Authors: Sigmund, Anna M., Winkler, Markus, Engelmayer, Sophia, Kugelmann, Daniela, Egu, Desalegn T., Steinert, Letyfee S., Fuchs, Michael, Hiermaier, Matthias, Radeva, Mariya Y., Bayerbach, Franziska C., Butz, Elisabeth, Kotschi, Stefan, Hudemann, Christoph, Hertl, Michael, Yeruva, Sunil, Schmidt, Enno, Yazdi, Amir S., Ghoreschi, Kamran, Vielmuth, Franziska, Waschke, Jens

Source: Nature Communications; 2/7/2023, Vol. 14 Issue 1, p1-1, 1p

Subject Terms: APREMILAST, PEMPHIGUS, KERATINOCYTES, EPIDERMIS, ADHESION

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