A Pro‐Fluorescent Ubiquitin‐Based Probe to Monitor Cysteine‐Based E3 Ligase Activity

Authors: Pérez Berrocal, David A., Vishwanatha, Thimmalapura M., Horn‐Ghetko, Daniel, Botsch, J. Josephine, Hehl, Laura A., Kostrhon, Sebastian, Misra, Mohit, Ðikić, Ivan, Geurink, Paul P., Dam, Hans, Schulman, Brenda A., Mulder, Monique P. C.

Source: Angewandte Chemie. 135(32)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194175786.0x000001&indx=1&recIds=ETOCvdc_100194175786.0x000001

A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding

Authors: Kostrhon, Sebastian, Kontaxis, Georg, Kaufmann, Tanja, Schirghuber, Erika, Kubicek, Stefan, Konrat, Robert, Slade, Dea

Source: In Journal of Biological Chemistry 27 October 2017 292(43):17643-17657

Noncanonical assembly, neddylation and chimeric cullin–RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex

Authors: Horn-Ghetko, Daniel, Hopf, Linus V. M., Tripathi-Giesgen, Ishita, Du, Jiale, Kostrhon, Sebastian, Vu, D. Tung, Beier, Viola, Steigenberger, Barbara, Prabu, J. Rajan, Stier, Luca, Bruss, Elias M., Mann, Matthias, Xiong, Yue, Schulman, Brenda A.

Source: Nature Structural and Molecular Biology; 20240101, Issue: Preprints p1-12, 12p

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.

Authors: Appel, Lisa-Marie, Franke, Vedran, Bruno, Melania, Grishkovskaya, Irina, Kasiliauskaite, Aiste, Kaufmann, Tanja, Schoeberl, Ursula E., Puchinger, Martin G., Kostrhon, Sebastian, Ebenwaldner, Carmen, Sebesta, Marek, Beltzung, Etienne, Mechtler, Karl, Lin, Gen, Vlasova, Anna, Leeb, Martin, Pavri, Rushad, Stark, Alexander, Akalin, Altuna, Stefl, Richard

Source: Nature Communications; 10/19/2021, Vol. 12 Issue 1, p1-24, 24p

Subject Terms: GENE expression, RNA polymerase II, EMBRYONIC stem cells, GENETIC regulation, NEURONAL differentiation

CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation

Authors: Kostrhon, Sebastian, Prabu, J. Rajan, Baek, Kheewoong, Horn-Ghetko, Daniel, von Gronau, Susanne, Klügel, Maren, Basquin, Jérôme, Alpi, Arno F., Schulman, Brenda A.

Source: Nature Chemical Biology; 20210101, Issue: Preprints p1-9, 9p

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