Switch to long-acting cabotegravir and rilpivirine in virologically suppressed adults with HIV in Africa (CARES): week 48 results from a randomised, multicentre, open-label, non-inferiority trial

Authors: Mugerwa, Henry, Tamale, William, Yiga, Joshua, Asaasira, Susan Esther, Kinyera, Nigel, Nambi, Christine, Nakiboneka, Dridah Luyirika, Kabatana, Rose, Kiyimba, Winfred, Ategeka, Gilbert, Yawe, Ibrahim, Alinaitwe, Adolf, Zawedde, Aidah, Wasswa, George, Arinda, Allan, Rweyora, Angela, Kangah, Mary Goretti, Cresswell, Fiona, Castelnuovo, Barbara, Kaimal, Arvind, Ogwal, Patience, Muhumuza, Neville, Okwero, Max, Ayebare, Peruth, Nakate, Vivian, Asienzo, Jesca, Mayanja, Hamza, Laker, Eva, Shah, Reena, Riunga, Felix, Onyango, Peter Odhiambo, Wanja, Josephine, Sayed, Shaheen, Gohil, Jaimini, Mungathia, Isaiah, Githuka, Alfred Mburu, Kibwage, Haron, Siika, Abraham Mosigisi, Wambui, Charity Kanyoro, Kirui, Viola Cherotich, Kipyego, Jairus, Sang, Natalie, Mokaya, Martha Mokeira Bisieri, Chepkorir, Consolata, Mboya, Chris Sande, Tonui, Ronald, Njulu, Florence, Kaziga, Hilda, Kosgei, Josphat, Sawe, Fredrick, Omol, Magdaline Adhiambo, Riziki, Faith, Daud, Ibrahim, Kimetto, Leelgo, Okumu, Billy Omalla, Lipuku, Francis, Sokhela, Simiso, Venter, Francois, Moller, Karlien, Nzuza, Nompumelelo, Ramela, Gontse, Tom, Noxolo, Nyamuzihwa, Tsitsi, Macholo, Philadelphia, Macebele, Hlamulani, Akpomiemie, Godspower, Naidoo, Logashvari, Jeenarain, Nitesha, Hurbans, Nivriti, Reddy, Mayuri, Mphisa, Gerald Thsepo, Kityo, Cissy, Paton, Nicholas, Mambule, Ivan Kiggundu, Opiyo, Kimton, Musaazi, Joseph, Otike, Caroline, Kabanyoro, Ritah, Sekajja, Francis, Nantumbwe, Sandra, Sekabira, Harriet, Ocitti, Paul, Ouma, Benson, Nankya, Immaculate, Ainembabazi, Pamela, Lötter, Melissa, Mohamed, Saeeda, Herbst, Madel, Peters, Tarryn, Mehta, Heena, Khan, Shaguftha, Kruger, Marlien, van Rein-van der Horst, Willemijn, Addo Boateng, Fafa, Van Solingen, Rodica, Vandermeulen, Kati, Van Eygen, Veerle, Crauwels, Herta, Luo, Donghan, Votto, Donna, Idahosa, Awhonukeh, Mwendia, Fridah, Klasko-Foster, Lynne, Bondal, Malavika, Eshun-Wilsonova, Ingrid, Mohammed, Perry, Spreen, William, D'Amico, Ronald, Kaleebu, Pontiano, Ojoo, Sylvia, Katana, Milly, Moosa, Yunus, Phiri, Sam, Munderi, Paula, Hill, Andrew, Mambule, Ivan K, Siika, Abraham, Möller, Karlien, Wambui, Charity, Paton, Nicholas I ^*

Source: In The Lancet Infectious Diseases October 2024 24(10):1083-1092

Brief Report: No Differences Between Lopinavir/Ritonavir and Nonnucleoside Reverse Transcriptase Inhibitor–Based Antiretroviral Therapy on Clearance of Plasmodium falciparum Subclinical Parasitemia in Adults Living With HIV Starting Treatment (A5297)

Authors: Shaffer, Douglas, Kumwenda, Johnstone, Chen, Huichao, Akelo, Victor, Angira, Francis, Kosgei, Josphat, Tonui, Ronald, Ssali, Francis, McKhann, Ashley, Hogg, Evelyn, Stewart, V. Ann, Murphy, Sean C., Coombs, Robert, Schooley, Robert

Source: Journal of acquired immune deficiency syndromes. 89(2):178-182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155558765.0x000001&indx=1&recIds=ETOCvdc_100155558765.0x000001

HepB-CpG vs HepB-Alum Vaccine in People With HIV and Prior Vaccine Nonresponse: The BEe-HIVe Randomized Clinical Trial.

Authors: Marks, Kristen M., Kang, Minhee, Umbleja, Triin, Cox, Andrea, Vigil, Karen J., Ta, Ngan T., Omoz-Oarhe, Ayotunde, Perazzo, Hugo, Kosgei, Josphat, Hatlen, Timothy, Price, Jennifer, Katsidzira, Leolin, Supparatpinyo, Khuanchai, Knowles, Kevin, Alston-Smith, Beverly L., Rathod, Parita, Sherman, Kenneth E.

Source: JAMA: Journal of the American Medical Association; 1/28/2025, Vol. 333 Issue 4, p295-306, 12p

Subject Terms: HEPATITIS associated antigen, HEPATITIS B vaccines, HEPATITIS B, ANTIBODY titer, HEPATITIS B virus

Pre‐exposure prophylaxis implementation gaps among people vulnerable to HIV acquisition: a cross‐sectional analysis in two communities in western Kenya, 2021–2023.

Authors: Romo, Matthew L., Schluck, Glenna, Kosgei, Josphat, Akoth, Christine, Bor, Rael, Langat, Deborah, Charles, Curtisha, Adjei, Paul, Gayle, Britt, LeeVan, Elyse, Chang, David, Yates, Adam, Yacovone, Margaret, Ake, Julie A., Sawe, Fred, Crowell, Trevor A.

Source: Journal of the International AIDS Society; Nov2024, Vol. 27 Issue 11, p1-8, 8p

Subject Terms: TRANSACTIONAL sex, DRUG abuse, SEXUALLY transmitted diseases, UNSAFE sex, HIV infections

Geographic Terms: KENYA

Safety and Immunogenicity of Accelerated Heterologous 2-Dose Ebola Vaccine Regimens in Adults With and Without HIV in Africa.

Authors: Mwesigwa, Betty, Sawe, Fredrick, Oyieko, Janet, Mwakisisile, Joel, Viegas, Edna, Akintunde, Gideon Akindiran, Kosgei, Josphat, Kokogho, Afoke, Ntinginya, Nyanda, Jani, Ilesh, Shukarev, Georgi, Hooper, Jay W, Kwilas, Steven A, Ward, Lucy A, Rusnak, Janice, Bounds, Callie, Overman, Rachel, Badorrek, Christopher S, Eller, Leigh Anne, Eller, Michael A

Source: Clinical Infectious Diseases; 10/15/2024, Vol. 79 Issue 4, p888-900, 13p

Subject Terms: PATIENT safety, DRUG side effects, RESEARCH funding, VACCINE effectiveness, HIV-positive persons, STATISTICAL sampling, BLIND experiment, CD4 lymphocyte count, ENZYME-linked immunosorbent assay, RANDOMIZED controlled trials, DESCRIPTIVE statistics, VACCINE immunogenicity, VIRAL vaccines, EBOLA virus, DRUG tolerance, EVALUATION

Geographic Terms: SUB-Saharan Africa

Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial

Authors: Moses, Agnes, Kanyama, Cecilia, Mukwekwerere, Pamela, Gudza, Ivy, Chauwa, Felluna, Ulaya, Godwin, Kutto, Irene, Cheruiyot, Priscilla, Okello, Clement, Nakaganda, Annet, Koskei, Geoffrey, Keter, Winnie, Netto, Juliana, Baião, Tamiris, Govender, Iveshni, O'Connell-Maritz, Jessica, Cain, Kevin, Okanda, John, Cornelissen, Lynne, Van Schalkwyk, Marije, Sikhosana, Rejoice, Ngcobo, Minenhle, Lee, Jeannette Y., Harrison, Taylor, Wachsman, William, Shin, Katherine, Evans, Scott, Rothenberg, Jennifer, Hosey, Lara, McCarthy, Sean, Martinez-Maza, Otoniel, Rinaldo, Charles, Dittmer, Dirk, Fletcher, Courtney, Rudek, Michelle, Asmelash, Aida, Hughes, Valery, Schouten, Jeffrey, Shugarts, David, Kujinga, Tapiwanashe, Zadzilka, Amanda, Kerui, Fredrick, Robertson, Debora, Rooney, James, Sewal, Krishna, Gottshall, Brian, Krown, Susan E ^*, Moser, Carlee B, MacPhail, Patrick, Matining, Roy M, Godfrey, Catherine, Caruso, Stephanie R, Hosseinipour, Mina C, Samaneka, Wadzanai, Nyirenda, Mulinda, Busakhala, Naftali W, Okuku, Fred M, Kosgei, Josphat, Hoagland, Brenda, Mwelase, Noluthando, Oliver, Vincent O, Burger, Henriette, Mngqibisa, Rosie, Nokta, Mostafa, Campbell, Thomas B, Borok, Margaret Z

Source: In The Lancet 11-17 April 2020 395(10231):1195-1207

Treatment of advanced AIDS-associated Kaposi sarcoma in resource-limited settings: a three-arm, open-label, randomised, non-inferiority trial

Authors: Krown, Susan E, Moser, Carlee B, MacPhail, Patrick, Matining, Roy M, Godfrey, Catherine, Caruso, Stephanie R, Hosseinipour, Mina C, Samaneka, Wadzanai, Nyirenda, Mulinda, Busakhala, Naftali W, Okuku, Fred M, Kosgei, Josphat, Hoagland, Brenda, Mwelase, Noluthando, Oliver, Vincent O, Burger, Henriette, Mngqibisa, Rosie, Nokta, Mostafa, Campbell, Thomas B, Borok, Margaret Z

Source: Lancet. 395(10231):1195-1207

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116308723.0x000001&indx=1&recIds=ETOCvdc_100116308723.0x000001

Impact of Early Antiretroviral Treatment Initiation on Performance of Cross-Sectional Incidence Assays

Authors: Klock, Ethan, Mwinnya, George, Eller, Leigh Anne, Fernandez, Reinaldo E., Kibuuka, Hannah, Nitayaphan, Sorachai, Kosgei, Josphat, Moore, Richard D., Robb, Merlin, Eshleman, Susan H., Laeyendecker, Oliver

Source: AIDS research and human retroviruses. 36(7):583-589

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150476906.0x000001&indx=1&recIds=ETOCvdc_100150476906.0x000001

Safety and Immunogenicity of PENNVAX-G DNA Prime Administered by Biojector 2000 or CELLECTRA Electroporation Device With Modified Vaccinia Ankara-CMDR Boost

Authors: Ake, Julie A., Schuetz, Alexandra, Pegu, Poonam, Wieczorek, Lindsay, Eller, Michael A., Kibuuka, Hannah, Sawe, Fredrick, Maboko, Leonard, Polonis, Victoria, Karasavva, Nicos, Weiner, David, Sekiziyivu, Arthur, Kosgei, Josphat, Missanga, Marco, Kroidl, Arne, Mann, Philipp, Ratto-Kim, Silvia, Eller, Leigh Anne, Earl, Patricia, Moss, Bernard, Dorsey-Spitz, Julie, Milazzo, Mark, Ouedraogo, G. Laissa, Rizvi, Farrukh, Yan, Jian, Khan, Amir S., Peel, Sheila, Sardesai, Niranjan Y., Michael, Nelson L., Ngauy, Viseth, Marovich, Mary, Robb, Merlin L.

Source: The Journal of Infectious Diseases, 2017 Nov 01. 216(9), 1080-1090.

Access URL: https://www.jstor.org/stable/26491420

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Authors: Lal, Kerri G., Kim, Dohoon, Costanzo, Margaret C., Creegan, Matthew, Leeansyah, Edwin, Dias, Joana, Paquin-Proulx, Dominic, Eller, Leigh Anne, Schuetz, Alexandra, Phuang-ngern, Yuwadee, Krebs, Shelly J., Slike, Bonnie M., Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Kosgei, Josphat, Sacdalan, Carlo, Ananworanich, Jintanat, Bolton, Diane L., Michael, Nelson L., Shacklett, Barbara L., Robb, Merlin L., Eller, Michael A., Sandberg, Johan K.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131056522.0x000001&indx=1&recIds=ETOCvdc_100131056522.0x000001

Clinical signs and symptoms associated with acute HIV infection from an intensely monitored cohort on 2 continents

Authors: Letizia, Andrew G., Eller, Leigh Anne, Bryant, Christopher, Dawson, Peter, Nitayaphan, Sorachai, Kosgei, Josphat, Kibuuka, Hannah, Maganga, Lucas, Kroon, Eugène, Sriplienchan, Somchai, Michael, Nelson L., O'Connell, Robert J., Kim, Jerome H., Robb, Merlin L.

Source: Medicine. 101(5):e28686-e28686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165404869.0x000001&indx=1&recIds=ETOCvdc_100165404869.0x000001

Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life.

Authors: Nelson, Bryan S, Tierney, Camlin, Persaud, Deborah, Jao, Jennifer, Cotton, Mark F, Bryson, Yvonne, Coletti, Anne, Ruel, Theodore D, Spector, Stephen A, Reding, Christina, Bacon, Kira, Costello, Diane, Perlowski, Charlotte, Cruz, Maria Leticia Santos, Kosgei, Josphat, Majji, Sai, Yin, Dwight E, Jean-Philippe, Patrick, Chadwick, Ellen G, Team, for the IMPAACT P1115

Source: Clinical Infectious Diseases; 2/1/2023, Vol. 76 Issue 3, pe744-e747, 4p

Subject Terms: HIV infections, CLINICAL trials, CONFIDENCE intervals, CROSS-sectional method, RESEARCH methodology, HIGHLY active antiretroviral therapy, CD4 lymphocyte count, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis software, CHILDREN

Prospective International Study of Incidence and Predictors of Immune Reconstitution Inflammatory Syndrome and Death in People Living With Human Immunodeficiency Virus and Severe Lymphopenia.

Authors: Sereti, Irini, Sheikh, Virginia, Shaffer, Douglas, Phanuphak, Nittaya, Gabriel, Erin, Wang, Jing, Nason, Martha C, Roby, Gregg, Ngeno, Hellen, Kirui, Fredrick, Pau, Alice, Mican, Joann M, Rupert, Adam, Bishop, Rachel, Agan, Brian, Chomchey, Nitiya, Teeratakulpisarn, Nipat, Tansuphaswadikul, Somsit, Langat, Deborah, Kosgei, Josphat

Source: Clinical Infectious Diseases; 8/1/2020, Vol. 71 Issue 3, p652-660, 9p

Subject Terms: BIOMARKERS, C-reactive protein, CONVALESCENCE, DECISION trees, HEMOGLOBINS, HIV infections, HIV-positive persons, LONGITUDINAL method, REFERENCE values, RISK assessment, WORLD health, ANTIRETROVIRAL agents, BODY mass index, DISEASE incidence, PROPORTIONAL hazards models, FIBRIN fibrinogen degradation products, IMMUNE reconstitution inflammatory syndrome, LYMPHOPENIA, DESCRIPTIVE statistics, CD4 lymphocyte count, DISEASE risk factors

Geographic Terms: KENYA, THAILAND, UNITED States

RANDOMIZED CONTROLLED TRIAL OF VRCO1 MONOCLONAL ANTIBODY DURING ACUTE HIV INFECTION.

Authors: Ake, Julie A., Sriplienchan, Somchai, Kosgei, Josphat, Kibuuka, Hannah, Mwakisisile, Joel, Subra, Caroline, Orndahl, Christine, Eller, Leigh Anne, Michael, Nelson L., Peel, Sheila A., Tressler, Randall, Koup, Richard A., Rolland, Morgane, Robb, Merlin L.

Source: Topics in Antiviral Medicine; Apr2023, Vol. 31 Issue 2, p170-170, 1/3p

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