Rapid downregulation of DICER is a hallmark of adipose tissue upon high-fat diet feeding

Authors: Madsen, Søren, Peluso, A. Augusto, Yonamine, Caio Y., Ingerslev, Lars R., Dall, Morten, Petersen, Patricia S.S., Plucinska, Kaja, Pradas-Juni, Marta, Moreno-Justicia, Roger, Gonzalez-Franquesa, Alba, Højlund, Kurt, Kornfeld, Jan-Wilhelm, Emanuelli, Brice, Vienberg, Sara G., Treebak, Jonas T.

Source: In Molecular and Cellular Endocrinology 1 January 2025 595

Nanopore sequencing unveils the complexity of the cold-activated murine brown adipose tissue transcriptome

Authors: Engelhard, Christoph Andreas, Khani, Sajjad, Derdak, Sophia, Bilban, Martin, Kornfeld, Jan-Wilhelm

Source: In iScience 18 August 2023 26(8)

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

Authors: Brandão, Bruna B., Madsen, Søren, Rabiee, Atefeh, Oliverio, Matteo, Ruiz, Gabriel P., Ferrucci, Danilo L., Branquinho, Jéssica L., Razolli, Daniela, Pinto, Silas, Nielsen, Thomas S., Festuccia, William T., Martins, Adriano S., Guerra, Beatriz A., Knittel, Thiago L., Søgaard, Ditte, Larsen, Steen, Helge, Jørn W., Brandauer, Josef, Velloso, Lício A., Emanuelli, Brice, Kornfeld, Jan-Wilhelm, Kahn, Ronald, Vienberg, Sara G., Zierath, Juleen R., Treebak, Jonas T., Mori, Marcelo A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Sep . 117(38), 23932-23941.

Access URL: https://www.jstor.org/stable/26969365

Mouse vascularized adipose spheroids: an organotypic model for thermogenic adipocytes.

Authors: Ingeborg Davidsen, Laura, Hagberg, Carolina E., Goitea, Victor, Meinild Lundby, Stine, Larsen, Steen, Frendø Ebbesen, Morten, Stanic, Natasha, Topel, Hande, Kornfeld, Jan-Wilhelm

Source: Frontiers in Endocrinology; 2024, p1-18, 18p

Subject Terms: WHITE adipose tissue, MICROPHYSIOLOGICAL systems, BROWN adipose tissue, ADIPOSE tissues, FAT cells, ENERGY metabolism, TISSUE scaffolds, GENE expression, ADIPOGENESIS

Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development

Authors: Mueller, Kristina M., Themanns, Madeleine, Friedbichler, Katrin, Kornfeld, Jan-Wilhelm, Esterbauer, Harald, Tuckermann, Jan P., Moriggl, Richard

Source: In Molecular and Cellular Endocrinology 25 September 2012 361(1-2):1-11

Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis

Authors: Mair, Markus, Zollner, Gernot, Schneller, Doris, Musteanu, Monica, Fickert, Peter, Gumhold, Judith, Schuster, Christian, Fuchsbichler, Andrea, Bilban, Martin, Tauber, Stefanie, Esterbauer, Harald, Kenner, Lukas, Poli, Valeria, Blaas, Leander, Kornfeld, Jan Wilhelm, Casanova, Emilio, Mikulits, Wolfgang, Trauner, Michael, Eferl, Robert

Source: In Gastroenterology 2010 138(7):2499-2508

Expression of Activated STAT5 in Neoplastic Mast Cells in Systemic Mastocytosis: Subcellular Distribution and Role of the Transforming Oncoprotein KIT D816V

Authors: Baumgartner, Christian, Cerny-Reiterer, Sabine, Sonneck, Karoline, Mayerhofer, Matthias, Gleixner, Karoline V., Fritz, Richard, Kerenyi, Marc, Boudot, Cedric, Gouilleux, Fabrice, Kornfeld, Jan-Wilhelm, Sillaber, Christian, Moriggl, Richard, Valent, Peter

Source: In The American Journal of Pathology 2009 175(6):2416-2429

Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells

Authors: Fernandez-Rebollo, Eduardo, Franzen, Julia, Goetzke, Roman, Hollmann, Jonathan, Ostrowska, Alina, Oliverio, Matteo, Sieben, Torsten, Rath, Björn, Kornfeld, Jan-Wilhelm, Wagner, Wolfgang

Source: In Stem Cell Reports 11 February 2020 14(2):201-209

Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.

Authors: Engblom, David, Kornfeld, Jan-Wilhelm, Schwake, Lukas

Source: Genes & Development; May 15 2007, Vol. 21 Issue 10, p1157-1162, 6p

Comprehensive Transcriptional Profiling and Mouse Phenotyping Reveals Dispensable Role for Adipose Tissue Selective Long Noncoding RNA Gm15551.

Authors: Engelhard, Christoph Andreas, Huang, Chien, Khani, Sajjad, Kasparek, Petr, Prochazka, Jan, Rozman, Jan, Reguera, David Pajuelo, Sedlacek, Radislav, Kornfeld, Jan-Wilhelm

Source: Non-Coding RNA; Jun2022, Vol. 8 Issue 3, p32-N.PAG, 19p

Subject Terms: LINCRNA, BROWN adipose tissue, PANCREATIC beta cells, ADIPOSE tissues, HIGH-fat diet, CELL physiology, FAT cells, MICE

Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations.

Authors: Burkert, Karsten, Taheri, Hadiseh, Hamad, Sarkawt, Oliverio, Matteo, Peinkofer, Gabriel, Kornfeld, Jan-Wilhelm, Harnying, Wacharee, Pfannkuche, Kurt, Hescheler, Jürgen, Berkessel, Albrecht, Šarić, Tomo

Source: Scientific Reports; 1/27/2021, Vol. 11 Issue 1, p1-17, 17p

Subject Terms: DIAMINES, CELL differentiation, HEART cells, PLURIPOTENT stem cells, SMALL molecules

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b.

Authors: Kornfeld, Jan-Wilhelm¹, Baitzel, Catherina¹, Könner, A. Christine¹, Nicholls, Hayley T.¹, Vogt, Merly C.¹, Herrmanns, Karolin², Scheja, Ludger³, Haumaitre, Cécile⁴, Wolf, Anna M.⁵, Knippschild, Uwe⁵, Seibler, Jost⁶, Cereghini, Silvia⁴, Heeren, Joerg³, Stoffel, Markus², Brüning, Jens C.¹

Source: Nature. 2/7/2013, Vol. 494 Issue 7435, p111-115. 5p. 4 Graphs.

Subject Terms: *OBESITY, *GLUCOSE metabolism disorders, *HYPOGLYCEMIC agents, *PANCREATIC secretions, *NUTRITION disorders

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Obesity-Induced CerS6-Dependent C16:0 Ceramide Production Promotes Weight Gain and Glucose Intolerance

Authors: Turpin, Sarah M., Nicholls, Hayley T., Willmes, Diana M., Mourier, Arnaud, Brodesser, Susanne, Wunderlich, Claudia M., Mauer, Jan, Xu, Elaine, Hammerschmidt, Philipp, Brönneke, Hella S., Trifunovic, Aleksandra, LoSasso, Giuseppe, Wunderlich, F. Thomas, Kornfeld, Jan-Wilhelm, Blüher, Matthias, Krönke, Martin, Brüning, Jens C.

Source: In Cell Metabolism 7 October 2014 20(4):678-686

Rapid Generation of Long Noncoding RNA Knockout Mice Using CRISPR/Cas9 Technology.

Authors: Hansmeier, Nils R., Widdershooven, Pia J. M., Khani, Sajjad, Kornfeld, Jan-Wilhelm

Source: Non-Coding RNA; Mar2019, Vol. 5 Issue 1, p1-12, 12p

Subject Terms: MICE, NON-coding RNA, CRISPRS, KNOCKOUT mice, CAENORHABDITIS elegans, TECHNOLOGY

s ·nr: a visual analytics framework for contextual analyses of private and public RNA-seq data.

Authors: Klemm, Paul, Frommolt, Peter, Kornfeld, Jan-Wilhelm

Source: BMC Genomics; 1/24/2019, Vol. 20 Issue 1, p1-12, 12p, 1 Color Photograph, 3 Diagrams, 1 Chart

Subject Terms: NUCLEOTIDE sequencing, VISUAL analytics, ARCHIVES, GENE expression, MOLECULAR biology, RNA sequencing

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