525 Diffuse Microglia Inflammation is Associated with Anti-Tumor Efficacy in Polio Virotherapy for Glioblastoma

Authors: Yang, Yuanfan, Brown, Michael, Zhang, Gao, Stevenson, Kevin, Mohme, Malte, Kornahrens, Reb, Bigner, Darrell, Lopez, Giselle, Gromeier, Matthias

Source: Neurosurgery. 69(1):118-119

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190138633.0x000001&indx=1&recIds=ETOCvdc_100190138633.0x000001

Polio virotherapy targets the malignant glioma myeloid infiltrate with diffuse microglia activation engulfing the CNS.

Authors: Yang, Yuanfan, Brown, Michael C, Zhang, Gao, Stevenson, Kevin, Mohme, Malte, Kornahrens, Reb, Bigner, Darell D, Ashley, David M, López, Giselle Y, Gromeier, Matthias

Source: Neuro-Oncology; Sep2023, Vol. 25 Issue 9, p1631-1643, 13p

CD155 is a putative therapeutic target in medulloblastoma.

Authors: Li, Sean, McLendon, Roger, Sankey, Eric, Kornahrens, Reb, Lyne, Anne-Marie, Cavalli, Florence Marie Géraldine, McKay, Zachary, Herndon II, James Emmett, Remke, Marc, Picard, Daniel, Gromeier, Matthias, Brown, Michael, Thompson, Eric Michael

Source: Clinical & Translational Oncology; Mar2023, Vol. 25 Issue 3, p696-705, 10p

ABL1 and ABL2 promote medulloblastoma leptomeningeal dissemination.

Authors: Jones, Jill K, Zhang, Hengshan, Lyne, Anne-Marie, Cavalli, Florence M G, Hassen, Wafa E, Stevenson, Kevin, Kornahrens, Reb, Yang, Yuanfan, Li, Sean, Dell, Samuel, Reitman, Zachary J, Herndon, James E, Hoj, Jacob, Pendergast, Ann Marie, Thompson, Eric M

Source: Neuro-Oncology Advances; 2023, Vol. 5 Issue 1, p1-11, 11p