Platelets, inflammation, and purinergic receptors in chronic kidney disease

Authors: Corken, Adam L., Ong, Vincz, Kore, Rajshekhar, Ghanta, Sai N., Karaduta, Oleg, Pathak, Rupak, Rose, Shannon, Porter, Craig, Jain, Nishank

Source: In Kidney International September 2024 106(3):392-399

Updates on New Therapies for Patients with CKD

Authors: Tarun, Tushar, Ghanta, Sai Nikhila, Ong, Vincz, Kore, Rajshekhar, Menon, Lakshmi, Kovesdy, Csaba, Mehta, Jawahar L., Jain, Nishank

Source: In Kidney International Reports January 2024 9(1):16-28

Proteomic analysis of transcription factors involved in the alteration of ischemic mouse heart as modulated by MSC exosomes

Authors: Kore, Rajshekhar A., Jenkins, Samir V., Jamshidi-Parsian, Azemat, Tackett, Alan J., Griffin, Robert J., Ayyadevara, Srinivas, Mehta, Jawahar L.

Source: In Biochemistry and Biophysics Reports July 2023 34

Mesenchymal stem cell treatment for hyperactive immune response in patients with COVID-19

Authors: Manoharan, Ragul, Kore, Rajshekhar A, Mehta, Jawahar L

Source: Immunotherapy. 14(13):1055-1065

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191698777.0x000001&indx=1&recIds=ETOCvdc_100191698777.0x000001

The structural basis of effective LOX-1 inhibition

Authors: Kore, Rajshekhar A, Bagchi, Ashim K, Varughese, Kottayil I, Mehta, Jawahar L

Source: Future medicinal chemistry. 14(10):731-743

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188671709.0x000001&indx=1&recIds=ETOCvdc_100188671709.0x000001

Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain.

Authors: Mainali, Nirjal, Li, Xiao, Wang, Xianwei, Balasubramaniam, Meenakshisundaram, Ganne, Akshatha, Kore, Rajshekhar, Shmookler Reis, Robert J., Mehta, Jawahar L., Ayyadevara, Srinivas

Source: Molecular & Cellular Biochemistry; Oct2024, Vol. 479 Issue 10, p2741-2753, 13p

Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma

Authors: Jamshidi-Parsian, Azemat, Griffin, Robert J., Kore, Rajshekhar A., Todorova, Valentina K., Makhoul, Issam

Source: In Experimental Cell Research 1 November 2018 372(1):16-24

Glutaminase inhibitor CB-839 increases radiation sensitivity of lung tumor cells and human lung tumor xenografts in mice

Authors: Boysen, Gunnar, Jamshidi-Parsian, Azemat, Davis, Mary A., Siegel, Eric R., Simecka, Christine M., Kore, Rajshekhar A., Dings, Ruud P. M., Griffin, Robert J.

Source: International journal of radiation biology. 95(4):436-442

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105368848.0x000001&indx=1&recIds=ETOCvdc_100105368848.0x000001

Modulation of dietary methionine intake elicits potent, yet distinct, anticancer effects on primary versus metastatic tumors

Authors: Miousse, Isabelle R., Tobacyk, Julia, Quick, Charles M., Jamshidi-Parsian, Azemat, Skinner, Charles M., Kore, Rajshekhar, Melnyk, Stepan B., Kutanzi, Kristy R., Xia, Fen, Griffin, Robert J.

Source: Carcinogenesis. 39(9):1117-1126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620722309&indx=1&recIds=ETOCRN620722309

Phosphorylation negatively regulates exosome mediated secretion of cryAB in glioma cells

Authors: Kore, Rajshekhar A., Abraham, Edathara C.

Source: In BBA - Molecular Cell Research February 2016 1863(2):368-377

Cardiac Fibrosis Following Myocardial Ischemia is Mitigated by Mesenchymal Stem Cell Exosomes

Authors: Kore, Rajshekhar, Wang, Xanwei, Ding, Zufeng, Parisian, A.J., Mehta, Jawahar

Source: FASEB journal. 35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123840596.0x000001&indx=1&recIds=ETOCvdc_100123840596.0x000001

Author Correction: Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes.

Authors: Kore, Rajshekhar A.¹ (AUTHOR), Henson, Jeffrey C.¹ (AUTHOR), Hamzah, Rabab N.^2,3 (AUTHOR), Griffin, Robert J.² (AUTHOR), Tackett, Alan J.⁴ (AUTHOR), Ding, Zufeng¹ (AUTHOR), Mehta, Jawahar L.¹ (AUTHOR) MehtaJL@uams.edu

Source: Scientific Reports. 5/12/2022, Vol. 12 Issue 1, p1-3. 3p.

Subject Terms: *EXOSOMES, *CYTOPROTECTION, *MESENCHYMAL stem cells, *CASPASES

Molecular events in MSC exosome mediated cytoprotection in cardiomyocytes.

Authors: Kore, Rajshekhar A.¹, Henson, Jeffrey C.¹, Hamzah, Rabab N.^2,3, Griffin, Robert J.², Tackett, Alan J.⁴, Ding, Zufeng¹, Mehta, Jawahar L.¹ MehtaJL@uams.edu

Source: Scientific Reports. 12/17/2019, Vol. 9 Issue 1, p1-12. 12p.

Subject Terms: *EXOSOMES, *CYTOPROTECTION, *HEART cells, *HYPOXEMIA, *LIPOPOLYSACCHARIDES, *LABORATORY rats

Higher Glycolysis in Circulating Leukocytes in Patients with CKD

Authors: Johnson, Lucas R., Jain, Nishank, Rahmatallah, Yasir, Coca Juaristi, Jon, Kore, Rajshekhar A.

Source: Journal of the American Society of Nephrology; October 2024, Vol. 35 Issue: 10, Number 10 Supplement 10

LOX‐1 is the prime target for mesenchymal stem cell exosome mediated cardioprotective effects

Authors: Kore, Rajshekhar A., Ding, Zufeng, Wang, Xiawei, Malhotra, Astha, Mehta, Jawahar L.

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140398759.0x000001&indx=1&recIds=ETOCvdc_100140398759.0x000001

Proteomic basis of modulation of postischemic fibrosis by MSC exosomes.

Authors: Kore, Rajshekhar A.¹, Xianwei Wang², Henson, Jeffrey Curran¹, Ding, Zufeng¹, Jamshidi-Parsian, Azemat³, Mehta, Jawahar L.¹ mehtajl@uams.edu

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Nov2021, Vol. 321 Issue 5, pR639-R654. 16p.

Subject Terms: *EXOSOMES, *CELLULAR signal transduction, *PROTEOMICS, *EXTRACELLULAR matrix, *MESENCHYMAL stem cells

MSC exosome-mediated cardioprotection in ischemic mouse heart comparative proteomics of infarct and peri-infarct areas.

Authors: Kore, Rajshekhar A., Wang, Xianwei, Ding, Zufeng, Griffin, Robert J., Tackett, Alan J., Mehta, Jawahar L.

Source: Molecular & Cellular Biochemistry; Apr2021, Vol. 476 Issue 4, p1691-1704, 14p

Glioma-derived exosomes drive the differentiation of neural stem cells to astrocytes.

Authors: Sharma, Krishna D., Schaal, Danielle, Kore, Rajshekhar A., Hamzah, Rabab N., Pandanaboina, Sahitya Chetan, Hayar, Abdallah, Griffin, Robert J., Srivatsan, Malathi, Reyna, Nathan S., Xie, Jennifer Yanhua

Source: PLoS ONE; 7/10/2020, Vol. 15 Issue 7, p1-17, 17p

Subject Terms: EXOSOMES, NEURAL stem cells, GLIAL fibrillary acidic protein, TRANSFORMING growth factors, HUMAN stem cells, MESENCHYMAL stem cells, CELL populations

564 Platelets and Leukocytes Interact to Modulate Inflammation in Patients with CKD.

Authors: Jain, Nishank¹, Kore, Rajshekhar¹, Arthur, John M¹, Ware, Jerry¹, Pathak, Rupak¹

Source: Journal of Clinical & Translational Science; 2024 Suppl 1, Vol. 8, p168-168, 1p

Authors' Reply: Platelet Count, Platelet Volume and CKD

Authors: Kore, Rajshekhar, Jadvani, Dharmik, Arthur, John M., Jain, Nishank

Source: Journal of the American Society of Nephrology; February 2024, Vol. 35 Issue: 2 p250-251, 2p