Skin immune-mesenchymal interplay within tertiary lymphoid structures promotes autoimmune pathogenesis in hidradenitis suppurativa

Authors: Yu, Wei-Wen ^{1, 20, 21}, Barrett, Joy N.P. ^{1, 20}, Tong, Jie ^{1, 20}, Lin, Meng-Ju ¹, Marohn, Meaghan ¹, Devlin, Joseph C. ^{2, 3}, Herrera, Alberto ⁴, Remark, Juliana ^{1, 3}, Levine, Jamie ¹, Liu, Pei-Kang ⁵, Fang, Victoria ^{6, 7, 8, 9}, Zellmer, Abigail M. ¹⁰, Oldridge, Derek A. ^{6, 10, 11}, Wherry, E. John ^{6, 8, 9}, Lin, Jia-Ren ¹², Chen, Jia-Yun ¹², Sorger, Peter ¹², Santagata, Sandro ^{12, 13}, Krueger, James G. ¹⁴, Ruggles, Kelly V. ^{2, 15}, Wang, Fei ^{16, 17}, Su, Chang ^{16, 17}, Koralov, Sergei B. ⁴, Wang, Jun ^{4, 18}, Chiu, Ernest S. ¹, Lu, Catherine P. ^{1, 19, 22, ∗}

Source: In Immunity 10 December 2024 57(12):2827-2842

Keratinocytes Present Staphylococcus aureus Enterotoxins and Promote Malignant and Nonmalignant T Cell Proliferation in Cutaneous T-Cell Lymphoma

Authors: Zeng, Ziao, Vadivel, Chella Krishna, Gluud, Maria, Namini, Martin R.J., Yan, Lang, Ahmad, Sana, Hansen, Morten Bagge, Coquet, Jonathan, Mustelin, Tomas, Koralov, Sergei B., Bonefeld, Charlotte Menne, Woetmann, Anders, Geisler, Carsten, Guenova, Emmanuella, Kamstrup, Maria R., Litman, Thomas, Gjerdrum, Lise-Mette R., Buus, Terkild B., Ødum, Niels

Source: In Journal of Investigative Dermatology December 2024 144(12):2789-2804

Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome

Authors: Vadivel, Chella Krishna, Willerslev-Olsen, Andreas, Namini, Martin R. J., Zeng, Ziao, Yan, Lang, Danielsen, Maria, Gluud, Maria, Pallesen, Emil M. H., Wojewoda, Karolina, Osmancevic, Amra, Hedebo, Signe, Chang, Yun-Tsan, Lindahl, Lise M., Koralov, Sergei B., Geskin, Larisa J., Bates, Susan E., Iversen, Lars, Litman, Thomas, Bech, Rikke, Wobser, Marion, Guenova, Emmanuella, Kamstrup, Maria R., Ødum, Niels, Buus, Terkild B.

Source: In Blood 11 April 2024 143(15):1496-1512

Role of Antigenic Stimulation in Cutaneous T-Cell Lymphomas

Authors: Gumina, Megan E., Hooper, Madeline J., Zhou, Xiaolong A., Koralov, Sergei B.

Source: In Journal of Investigative Dermatology April 2024 144(4):755-763

mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

Authors: Ivanova, Ellie N. ^{1, 14}, Shwetar, Jasmine ^{2, 3, 14}, Devlin, Joseph C. ^{2, 3, 14}, Buus, Terkild B. ^{1, 4, 14}, Gray-Gaillard, Sophie ⁵, Koide, Akiko ^{6, 8}, Cornelius, Amber ⁵, Samanovic, Marie I. ^{5, 6}, Herrera, Alberto ¹, Mimitou, Eleni P. ^{9, 12}, Zhang, Chenzhen ³, Karmacharya, Trishala ⁵, Desvignes, Ludovic ^{5, 6, 10}, Ødum, Niels ⁴, Smibert, Peter ^{9, 13}, Ulrich, Robert J. ^{5, 6}, Mulligan, Mark J. ⁵, Koide, Shohei ^{8, 11}, Ruggles, Kelly V. ^{2, ∗}, Herati, Ramin S. ^{5, 6, 7, ∗∗}, Koralov, Sergei B. ^{1, 15, ∗∗∗}

Source: In iScience 15 December 2023 26(12)

KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

Authors: Zavitsanou, Anastasia-Maria, Pillai, Ray, Hao, Yuan, Wu, Warren L., Bartnicki, Eric, Karakousi, Triantafyllia, Rajalingam, Sahith, Herrera, Alberto, Karatza, Angeliki, Rashidfarrokhi, Ali, Solis, Sabrina, Ciampricotti, Metamia, Yeaton, Anna H., Ivanova, Ellie, Wohlhieter, Corrin A., Buus, Terkild B., Hayashi, Makiko, Karadal-Ferrena, Burcu, Pass, Harvey I., Poirier, John T., Rudin, Charles M., Wong, Kwok-Kin, Moreira, Andre L., Khanna, Kamal M., Tsirigos, Aristotelis, Papagiannakopoulos, Thales, Koralov, Sergei B.

Source: In Cell Reports 28 November 2023 42(11)

Endolysin Inhibits Skin Colonization by Patient-Derived Staphylococcus Aureus and Malignant T-Cell Activation in Cutaneous T-Cell Lymphoma

Authors: Pallesen, Emil M.H., Gluud, Maria, Vadivel, Chella Krishna, Buus, Terkild B., de Rooij, Bob, Zeng, Ziao, Ahmad, Sana, Willerslev-Olsen, Andreas, Röhrig, Christian, Kamstrup, Maria R., Bay, Lene, Lindahl, Lise, Krejsgaard, Thorbjørn, Geisler, Carsten, Bonefeld, Charlotte M., Iversen, Lars, Woetmann, Anders, Koralov, Sergei B., Bjarnsholt, Thomas, Frieling, Johan, Schmelcher, Mathias, Ødum, Niels

Source: In Journal of Investigative Dermatology September 2023 143(9):1757-1768

Disruption of the early-life microbiota alters Peyer’s patch development and germinal center formation in gastrointestinal-associated lymphoid tissue

Authors: Borbet, Timothy C. ¹, Pawline, Miranda B. ¹, Li, Jackie ¹, Ho, Melody L. ¹, Yin, Yue Sandra ^{1, 2}, Zhang, Xiaozhou ³, Novikova, Ekaterina ¹, Jackson, Katelyn ^{1, 4}, Mullins, Briana J. ¹, Ruiz, Victoria E. ¹, Hines, Marcus J. ¹, Zhang, Xue-Song ^{1, 2}, Müller, Anne ³, Koralov, Sergei B. ^{1, ∗}, Blaser, Martin J. ^{1, 2, 5, ∗∗}

Source: In iScience 16 June 2023 26(6)

Malignant T cells induce skin barrier defects through cytokine-mediated JAK/STAT signaling in cutaneous T-cell lymphoma

Authors: Gluud, Maria, Pallesen, Emil M. H., Buus, Terkild B., Gjerdrum, Lise Mette Rahbek, Lindahl, Lise M., Kamstrup, Maria R., Bzorek, Michael, Danielsen, Maria, Bech, Rikke, Monteiro, Madalena N., Blümel, Edda, Willerslev-Olsen, Andreas, Lykkebo-Valløe, Anders, Vadivel, Chella Krishna, Krejsgaard, Thorbjørn, Bonefeld, Charlotte Menne, Geisler, Carsten, Becker, Jürgen C., Koralov, Sergei B., Iversen, Lars, Litman, Thomas, Woetmann, Anders, Ødum, Niels ^∗

Source: In Blood 12 January 2023 141(2):180-193

Influence of the early-life gut microbiota on the immune responses to an inhaled allergen

Authors: Borbet, Timothy C., Pawline, Miranda B., Zhang, Xiaozhou, Wipperman, Matthew F., Reuter, Sebastian, Maher, Timothy, Li, Jackie, Iizumi, Tadasu, Gao, Zhan, Daniele, Megan, Taube, Christian, Koralov, Sergei B., Müller, Anne, Blaser, Martin J.

Source: In Mucosal Immunology August 2022 15(5):1000-1011

Multimodal single-cell analysis of cutaneous T-cell lymphoma reveals distinct subclonal tissue-dependent signatures

Authors: Herrera, Alberto ^*, Cheng, Anthony ^*, Mimitou, Eleni P., Seffens, Angelina, George, Dean, Bar-Natan, Michal, Heguy, Adriana, Ruggles, Kelly V., Scher, Jose U., Hymes, Kenneth, Latkowski, Jo-Ann, Ødum, Niels, Kadin, Marshall E., Ouyang, Zhengqing, Geskin, Larisa J., Smibert, Peter, Buus, Terkild B. ^**, Koralov, Sergei B. ^*

Source: In Blood 21 October 2021 138(16):1456-1464

Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5‒Dependent miR-155 Expression in Cutaneous T-Cell Lymphoma

Authors: Willerslev-Olsen, Andreas, Gjerdrum, Lise Mette Rahbek, Lindahl, Lise M., Buus, Terkild B., Pallesen, Emil M.H., Gluud, Maria, Bzorek, Michael, Nielsen, Boye S., Kamstrup, Maria R., Rittig, Anne Hald, Bonefeld, Charlotte M., Krejsgaard, Thorbjørn, Geisler, Carsten, Koralov, Sergei B., Litman, Thomas, Becker, Jurgen C., Woetmann, Anders, Iversen, Lars, Odum, Niels

Source: In Journal of Investigative Dermatology October 2021 141(10):2449-2458

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

Authors: Lu, Qiao, Liu, Jia, Zhao, Shuai, Gomez Castro, Maria Florencia, Laurent-Rolle, Maudry, Dong, Jianbo, Ran, Xiaojuan, Damani-Yokota, Payal, Tang, Hongzhen, Karakousi, Triantafyllia, Son, Juhee, Kaczmarek, Maria E., Zhang, Ze, Yeung, Stephen T., McCune, Broc T., Chen, Rita E., Tang, Fei, Ren, Xianwen, Chen, Xufeng, Hsu, Jack C.C., Teplova, Marianna, Huang, Betty, Deng, Haijing, Long, Zhilin, Mudianto, Tenny, Jin, Shumin, Lin, Peng, Du, Jasper, Zang, Ruochen, Su, Tina Tianjiao, Herrera, Alberto, Zhou, Ming, Yan, Renhong, Cui, Jia, Zhu, James, Zhou, Qiang, Wang, Tao, Ma, Jianzhu, Koralov, Sergei B., Zhang, Zemin, Aifantis, Iannis, Segal, Leopoldo N., Diamond, Michael S., Khanna, Kamal M., Stapleford, Kenneth A., Cresswell, Peter, Liu, Yue, Ding, Siyuan, Xie, Qi, Wang, Jun

Source: In Immunity 8 June 2021 54(6):1304-1319

MicroRNA regulation of B cell receptor signaling

Authors: Borbet, Timothy C., Hines, Marcus J., Koralov, Sergei B.

Source: Immunological reviews. 304(1):111-125

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135917716.0x000001&indx=1&recIds=ETOCvdc_100135917716.0x000001

Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

Authors: Shin, Boyoung, Benavides, Gloria A., Geng, Jianlin, Koralov, Sergei B., Hu, Hui, Darley-Usmar, Victor M., Harrington, Laurie E.

Source: In Cell Reports 11 February 2020 30(6):1898-1909

Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

Authors: LeBoeuf, Sarah E., Wu, Warren L., Karakousi, Triantafyllia R., Karadal, Burcu, Jackson, S. RaElle, Davidson, Shawn M., Wong, Kwok-Kin, Koralov, Sergei B., Sayin, Volkan I., Papagiannakopoulos, Thales

Source: In Cell Metabolism 4 February 2020 31(2):339-350

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

Authors: Kaufmann, Ulrike, Kahlfuss, Sascha, Yang, Jun, Ivanova, Elitza, Koralov, Sergei B., Feske, Stefan

Source: In Cell Metabolism 7 May 2019 29(5):1104-1118

Distinct Requirements of CHD4 during B Cell Development and Antibody Response

Authors: Yen, Wei-Feng, Sharma, Rahul, Cols, Montserrat, Lau, Colleen M., Chaudhry, Ashutosh, Chowdhury, Priyanka, Yewdell, William T., Vaidyanathan, Bharat, Sun, Amy, Coffre, Maryaline, Pucella, Joseph N., Chen, Chun-Chin, Jasin, Maria, Sun, Joseph C., Rudensky, Alexander Y., Koralov, Sergei B., Chaudhuri, Jayanta

Source: In Cell Reports 30 April 2019 27(5):1472-1486

Low SATB1 Expression Promotes IL-5 and IL-9 Expression in Sézary Syndrome

Authors: Herrera, Alberto, Fredholm, Simon, Cheng, Anthony, Mimitou, Eleni P., Seffens, Angelina, Bar-Natan, Michal, Sun, Amy, Latkowski, Jo-Ann, Willerslew-Olsen, Andreas, Buus, Terkild B., Gluud, Maria, Krejsgaard, Thorbjørn, Torres-Rusillo, Sara, Bonefeld, Charlotte Menné, Woetmann, Anders, Geisler, Carsten, Geskin, Larisa J., Ouyang, Zhengqing, Smibert, Peter, Ødum, Niels, Koralov, Sergei B.

Source: Journal of investigative dermatology. 140(3):713-716

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099426634.0x000001&indx=1&recIds=ETOCvdc_100099426634.0x000001

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

Authors: Cantor, David J., King, Bryan, Blumenberg, Lili, DiMauro, Teresa, Aifantis, Iannis, Koralov, Sergei B., Skok, Jane A., David, Gregory

Source: In Cell Reports 2 January 2019 26(1):108-118