International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023

Authors: Burris, Thomas P. ^{1, *}, de Vera, Ian Mitchelle S. ¹, Cote, Isabelle ¹, Flaveny, Colin A. ¹, Wanninayake, Udayanga S. ¹, Chatterjee, Arindam ¹, Walker, John K. ¹, Steinauer, Nickolas ¹, Zhang, Jinsong ¹, Coons, Laurel A. ¹, Korach, Kenneth S. ¹, Cain, Derek W. ², Hollenberg, Anthony N. ², Webb, Paul ², Forrest, Douglas ², Jetten, Anton M. ², Edwards, Dean P. ², Grimm, Sandra L. ², Hartig, Sean ², Lange, Carol A. ², Richer, Jennifer K. ², Sartorius, Carol A. ², Tetel, Marc ², Billon, Cyrielle ², Elgendy, Bahaa ², Hegazy, Lamees ², Griffett, Kristine ², Peinetti, Nahuel ², Burnstein, Kerry L. ², Hughes, Travis S. ², Sitaula, Sadichha ², Stayrook, Keitch R. ², Culver, Alexander ², Murray, Meghan H. ², Finck, Brian N. ², Cidlowski, John A. ²

Source: In Pharmacological Reviews November 2023 75(6):1233-1318

Erythropoietin reduces fat mass in female mice lacking estrogen receptor alpha

Authors: Lee, Jeeyoung, Walter, Mary F., Korach, Kenneth S., Noguchi, Constance Tom

Source: In Molecular Metabolism March 2021 45

Postnatal Ovarian Transdifferentiation in the Absence of Estrogen Receptor Signaling Is Dependent on Genetic Background.

Authors: Binder, April K, Burns, Katherine A, Rodriguez, Karina F, Hamilton, Katherine, Villena, Fernando Pardo-Manuel de, Korach, Kenneth S

Source: Endocrinology; Jan2025, Vol. 166 Issue 1, p1-15, 15p

Subject Terms: GENE expression, SERTOLI cells, ESTROGEN receptors, GRANULOSA cells, CELL differentiation

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Nuclear hormone receptors

Authors: Alexander, Stephen P H, Cidlowski, John A, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Coons, Laurel, Fuller, Peter J., Korach, Kenneth S., Young, Morag J.

Source: British journal of pharmacology. 178:S246-S263

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140911779.0x000001&indx=1&recIds=ETOCvdc_100140911779.0x000001

Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice

Authors: Hewitt, Sylvia C. ^*, Grimm, Sara A., Wu, San-Pin, DeMayo, Francesco J., Korach, Kenneth S.

Source: In Journal of Biological Chemistry 19 June 2020 295(25):8387-8400

A distal super enhancer mediates estrogen-dependent mouse uterine–specific gene transcription of Igf1 (insulin-like growth factor 1)

Authors: Hewitt, Sylvia C., Lierz, Sydney L., Garcia, Marleny, Hamilton, Katherine J., Gruzdev, Artiom, Grimm, Sara A., Lydon, John P., Demayo, Francesco J. ^**, Korach, Kenneth S.

Source: In Journal of Biological Chemistry 21 June 2019 294(25):9746-9759

Decoding the Inversion Symmetry Underlying Transcription Factor DNA-Binding Specificity and Functionality in the Genome

Authors: Coons, Laurel A., Burkholder, Adam B., Hewitt, Sylvia C., McDonnell, Donald P., Korach, Kenneth S.

Source: In iScience 31 May 2019 15:552-591

Long-Term Follow-Up and Treatment of a Female With Complete Estrogen Insensitivity

Authors: Brakta, Soumia, Chorich, Lynn P, Kim, Hyung-Goo, Coons, Laurel A, Katzenellenbogen, John A, Hall, Janet E, Korach, Kenneth S, Layman, Lawrence C

Source: Journal of clinical endocrinology & metabolism. 105(5):1478-1488

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115222843.0x000001&indx=1&recIds=ETOCvdc_100115222843.0x000001

The genomic regulatory elements for estrogen receptor alpha transactivation‐function‐1 regulated genes

Authors: Arao, Yukitomo, Hamilton, Katherine J., Grimm, Sara A., Korach, Kenneth S.

Source: FASEB journal. 34(12):16003-16021

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112223900.0x000001&indx=1&recIds=ETOCvdc_100112223900.0x000001

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

Authors: La Merrill, Michele A., Vandenberg, Laura N., Smith, Martyn T., Goodson, William, Browne, Patience, Patisaul, Heather B., Guyton, Kathryn Z., Kortenkamp, Andreas, Cogliano, Vincent J., Woodruff, Tracey J., Rieswijk, Linda, Sone, Hideko, Korach, Kenneth S., Gore, Andrea C., Zeise, Lauren, Zoeller, R. Thomas

Source: Nature reviews.Endocrinology. 16(1):45-57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193261810.0x000001&indx=1&recIds=ETOCvdc_100193261810.0x000001

Activation of hepatic estrogen receptor-α increases energy expenditure by stimulating the production of fibroblast growth factor 21 in female mice

Authors: Allard, Camille, Bonnet, Fabrice, Xu, Beibei, Coons, Laurel, Albarado, Diana, Hill, Cristal, Fagherazzi, Guy, Korach, Kenneth S., Levin, Ellis R., Lefante, John, Morrison, Christopher, Mauvais-Jarvis, Franck

Source: In Molecular Metabolism April 2019 22:62-70

Nongenomic ERα-AMPK Signaling Regulates Sex-Dependent Bcrp Transport Activity at the Blood-Brain Barrier.

Authors: Banks, David B, Lierz, Sydney L, Cannon, Ronald E, Korach, Kenneth S

Source: Endocrinology; Aug2024, Vol. 165 Issue 8, p1-11, 11p

Subject Terms: BLOOD-brain barrier, SELECTIVE estrogen receptor modulators, ATP-binding cassette transporters, ENDOCRINE disruptors, PERIPHERAL circulation, ESTROGEN receptors

DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure

Authors: Li, Yin, Hamilton, Katherine J., Wang, Tianyuan, Coons, Laurel A., Jefferson, Wendy N., Li, Ruifang, Wang, Yu, Grimm, Sara A., Ramsey, J. Tyler, Liu, Liwen, Gerrish, Kevin E., Williams, Carmen J., Wade, Paul A., Korach, Kenneth S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 May 01. 115(18), E4189-E4198.

Access URL: https://www.jstor.org/stable/26508767

N-terminal transactivation function, AF-1, of estrogen receptor alpha controls obesity through enhancement of energy expenditure

Authors: Arao, Yukitomo, Hamilton, Katherine J., Lierz, Sydney L., Korach, Kenneth S.

Source: In Molecular Metabolism December 2018 18:68-78

Estrogen receptor beta maintains expression of KLF15 to prevent cardiac myocyte hypertrophy in female rodents

Authors: Hoa, Neil, Ge, Lisheng, Korach, Kenneth S., Levin, Ellis R.

Source: In Molecular and Cellular Endocrinology 15 July 2018 470:240-250

Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes

Authors: Xu, Beibei, Allard, Camille, Alvarez-Mercado, Ana I., Fuselier, Taylor, Kim, Jun Ho, Coons, Laurel A., Hewitt, Sylvia C., Urano, Fumihiko, Korach, Kenneth S., Levin, Ellis R., Arvan, Peter, Floyd, Z. Elizabeth, Mauvais-Jarvis, Franck

Source: In Cell Reports 3 July 2018 24(1):181-196

The F domain of estrogen receptor α is involved in species-specific, tamoxifen-mediated transactivation

Authors: Arao, Yukitomo, Korach, Kenneth S.

Source: In Journal of Biological Chemistry 1 June 2018 293(22):8495-8507

Experimental models for evaluating non-genomic estrogen signaling

Authors: Stefkovich, Megan L., Arao, Yukitomo, Hamilton, Katherine J., Korach, Kenneth S.

Source: In Steroids May 2018 133:34-37

Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress

Authors: Zhou, Zhenqi, Ribas, Vicent, Rajbhandari, Prashant, Drew, Brian G., Moore, Timothy M., Fluitt, Amy H., Reddish, Britany R., Whitney, Kate A., Georgia, Senta, Vergnes, Laurent, Reue, Karen, Liesa, Marc, Shirihai, Orian, van der Bliek, Alexander M., Chi, Nai-Wen ^**, Mahata, Sushil K. ^**, Tiano, Joseph P., Hewitt, Sylvia C., Tontonoz, Peter, Korach, Kenneth S., Mauvais-Jarvis, Franck, Hevener, Andrea L.

Source: In Journal of Biological Chemistry 30 March 2018 293(13):4735-4751

MicroRNA let-7 Downregulates Ligand-Independent Estrogen Receptor—mediated Male-Predominant Pulmonary Fibrosis

Authors: Elliot, Sharon, Periera-Simon, Simone, Xia, Xiaomei, Catanuto, Paola, Rubio, Gustavo, Shahzeidi, Shahriar, El Salem, Fadi, Shapiro, Josh, Briegel, Karoline, Korach, Kenneth S.

Source: American journal of respiratory and critical care medicine. 200(10):1246-1257

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622279329&indx=1&recIds=ETOCRN622279329