Anti-retinal immune response in sarcoid uveitis: A potential role for PCLO as an antigenic target

Authors: Schrijver, Benjamin ^a, Kolijn, P. Martijn ^a, Hasib, Saad H. ^a, ten Berge, Josianne C.E.M. ^b, Putera, Ikhwanuliman ^{a, b, c, d}, Nagtzaam, Nicole M.A. ^a, van Holten Neelen, J. Conny P.A. ^a, Langerak, Anton W. ^a, Schreurs, Marco W.J. ^a, van Hagen, P. Martin ^{a, c}, Dik, Willem A. ^{a, ⁎}

Source: In Journal of Autoimmunity February 2025 151

Potential Biomarkers for Noninfectious Scleritis Identified by Serum and Tear Fluid Proteomics

Authors: Vergouwen, Daphne P.C., Kolijn, P. Martijn, de Hoog, Joeri, de Boer, Joke H., Los, Leonoor I., Gijs, Marlies, Erckens, Roel J., de Jong, Pascal H.P., Rothova, Aniki, Ten Berge, Josianne C., Schreurs, Marco W.J.

Source: In Ophthalmology Science January-February 2024 4(1)

Immune dysregulation as a leading principle for lymphoma development in diverse immunological backgrounds

Authors: Kolijn, P. Martijn, Langerak, Anton W.

Source: In Immunology Letters November 2023 263:46-59

EuroClonality-NGS Recommendations for Evaluation of B-Cell Clonality Analysis by Next-Generation Sequencing: A Structured Approach with the DEPART Algorithm

Authors: van den Brand, Michiel, Möbs, Markus, Otto, Franziska, Kroeze, Leonie I., Gonzalez de Castro, David, Stamatopoulos, Kostas, Davi, Frederic, Bravetti, Clotilde, Kolijn, P. Martijn, Vlachonikola, Elisavet, Stewart, J. Peter, Pott, Christiane, Hummel, Michael, Darzentas, Nikos, Langerak, Anton W., Fend, Falko, Groenen, Patricia J.T.A.

Source: In The Journal of Molecular Diagnostics October 2023 25(10):729-739

Detecting measurable residual disease beyond 10−4 by an IGHV leader-based NGS approach improves prognostic stratification in CLL

Authors: Hengeveld, Paul J., van der Klift, Michèle Y., Kolijn, P. Martijn, Davi, Frédéric, Kavelaars, François G., de Jonge, Evert, Robrecht, Sandra, Assmann, Jorn L. J. C., van der Straten, Lina, Ritgen, Matthias, Westerweel, Peter E., Fischer, Kirsten, Goede, Valentin, Hallek, Michael, Levin, Mark-David ^∗, Langerak, Anton W. ^{∗, ∗}

Source: In Blood 2 February 2023 141(5):519-528

High-risk subtypes of chronic lymphocytic leukemia are detectable as early as 16 years prior to diagnosis

Authors: Kolijn, P. Martijn ^*, Hosnijeh, Fatemeh Saberi ^*, Späth, Florentin ^*, Hengeveld, Paul J., Agathangelidis, Andreas, Saleh, Manal, Casabonne, Delphine, Benavente, Yolanda, Jerkeman, Mats, Agudo, Antonio, Barricarte, Aurelio, Besson, Caroline, Sánchez, Maria-Jose, Chirlaque, María-Dolores, Masala, Giovanna, Sacerdote, Carlotta, Grioni, Sara, Schulze, Matthias B., Nieters, Alexandra, Engelfriet, Peter, Hultdin, Magnus, McKay, James D., Vermeulen, Roel C.H., Langerak, Anton W. ^*

Source: In Blood 10 March 2022 139(10):1557-1563

Local actin dynamics couple speed and persistence in a cellular Potts model of cell migration

Authors: Wortel, Inge M.N., Niculescu, Ioana, Kolijn, P. Martijn, Gov, Nir S., de Boer, Rob J., Textor, Johannes

Source: In Biophysical Journal 6 July 2021 120(13):2609-2622

Reading the B-cell receptor immunome in chronic lymphocytic leukemia: revelations and applications

Authors: Hengeveld, Paul J., Levin, Mark-David, Kolijn, P. Martijn, Langerak, Anton W.

Source: In Experimental Hematology January 2021 93:14-24

The need for a cancer exposome atlas: a scoping review.

Authors: Young, Anna S, Mullins, Catherine E, Sehgal, Neha, Vermeulen, Roel C H, Kolijn, P Martijn, Vlaanderen, Jelle, Rahman, Mohammad L, Birmann, Brenda M, Barupal, Dinesh, Lan, Qing, Rothman, Nathaniel, Walker, Douglas I

Source: JNCI Cancer Spectrum; Feb2025, Vol. 9 Issue 1, p1-16, 16p

Subject Terms: DISEASE risk factors, ENVIRONMENTAL exposure, EPIDEMIOLOGY of cancer, CANCER susceptibility, AIR quality

Treatment with obinutuzumab plus venetoclax reshapes the TRB repertoire of CLL patients.

Authors: Hengeveld, Paul J., Schilperoord-Vermeulen, Joyce, Kolijn, P. Martijn, Dubois, Julie M. N., Westerweel, Peter E., Kersting, Sabina, Kater, Arnon P., Levin, Mark-David, Langerak, Anton W.

Source: Blood Cancer Journal; 1/7/2025, Vol. 15 Issue 1, p1-5, 5p

Subject Terms: SARS-CoV-2, SOMATOMEDIN A, CYTOTOXIC T cells, B cell receptors, T cell receptors

Clinical performance of a novel and rapid bioassay for detection of thyroid-stimulating immunoglobulins in Graves’ orbitopathy patients: a comparison with two commonly used immunoassays.

Authors: Hötte, Gijsbert J., de Bie, Maaike, de Keizer, Ronald O. B., Kolijn, P. Martijn, Drexhage, Roosmarijn C., Veenbergen, Sharon, Versnel, Marjan A., van Hagen, P. Martin, Paridaens, Dion, Dik, Willem A.

Source: Frontiers in Endocrinology; 2024, p1-13, 13p

Subject Terms: RECEIVER operating characteristic curves, SYSTEMIC lupus erythematosus, LOGISTIC regression analysis, HORMONE receptors, RECEPTOR antibodies

A serum B-lymphocyte activation signature is a key distinguishing feature of the immune response in sarcoidosis compared to tuberculosis.

Authors: Putera, Ikhwanuliman, Schrijver, Benjamin, Kolijn, P. Martijn, van Stigt, Astrid C., ten Berge, Josianne C. E. M., IJspeert, Hanna, Nagtzaam, Nicole M. A., Swagemakers, Sigrid M. A., van Laar, Jan A. M., Agrawal, Rupesh, Rombach, Saskia M., van Hagen, P. Martin, La Distia Nora, Rina, Dik, Willem A.

Source: Communications Biology; 9/10/2024, Vol. 7 Issue 1, p1-13, 13p

Subject Terms: BLOOD proteins, SARCOIDOSIS, CELLULAR signal transduction, UVEITIS, TUBERCULOSIS

Dendritic Cell–Based Immunotherapy in Patients With Resected Pancreatic Cancer.

Authors: van 't Land, Freek R.^1,2 (AUTHOR), Willemsen, Marcella² (AUTHOR), Bezemer, Koen^2,3 (AUTHOR), van der Burg, Sjoerd H.⁴ (AUTHOR), van den Bosch, Thierry P.P.⁵ (AUTHOR), Doukas, Michail⁵ (AUTHOR), Fellah, Amine^1,2 (AUTHOR), Kolijn, P. Martijn⁶ (AUTHOR), Langerak, Anton W.⁶ (AUTHOR), Moskie, Miranda^1,2 (AUTHOR), van der Oost, Elise¹ (AUTHOR), Rozendaal, Nina E.M.² (AUTHOR), Baart, Sara J.^2,7 (AUTHOR), Aerts, Joachim G.J.V.² (AUTHOR), van Eijck, Casper H.J.^1,2 (AUTHOR) c.vaneijck@erasmusmc.nl

Source: Journal of Clinical Oncology. 9/10/2024, Vol. 42 Issue 26, p3083-3093. 12p.

Vitreous proteomics, a gateway to improved understanding and stratification of diverse uveitis aetiologies.

Authors: Schrijver, Benjamin¹ (AUTHOR), Kolijn, P. Martijn¹ (AUTHOR), ten Berge, Josianne C.E.M.² (AUTHOR), Nagtzaam, Nicole M.A.¹ (AUTHOR), van Rijswijk, Angelique L.C.T.¹ (AUTHOR), Swagemakers, Sigrid M.A.³ (AUTHOR), van der Spek, Peter J.³ (AUTHOR), Missotten, Tom O.A.R.⁴ (AUTHOR), van Velthoven, Mirjam E.J.⁴ (AUTHOR), de Hoog, Joeri² (AUTHOR), van Hagen, P. Martin^1,5 (AUTHOR), Langerak, Anton W.¹ (AUTHOR), Dik, Willem A.¹ (AUTHOR) w.dik@erasmusmc.nl

Source: Acta Ophthalmologica (1755375X). Jun2022, Vol. 100 Issue 4, p403-413. 11p.

Subject Terms: *UVEITIS, *EYE inflammation, *PROTEOMICS, *IRIDOCYCLITIS, *RANDOM forest algorithms, *CANCER diagnosis

Thyroid stimulating immunoglobulin concentration is associated with disease activity and predicts response to treatment with intravenous methylprednisolone in patients with Graves' orbitopathy.

Authors: Hötte, Gijsbert J., Kolijn, P. Martijn, de Bie, Maaike, de Keizer, Ronald O. B., Medici, Marco, van der Weerd, Kim, van Hagen, P. Martin, Paridaens, Dion, Dik, Willem A.

Source: Frontiers in Endocrinology; 2024, p1-12, 12p

Subject Terms: THYROTROPIN receptors, THYROID gland function tests, METHYLPREDNISOLONE, THYROID gland, BINDING site assay, MULTIVARIATE analysis, DISEASE duration

Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis

Authors: Kolijn, P. Martijn, Späth, Florentin, Khouja, Mouhamad, Hengeveld, Paul J., van der Straten, Lina, Darzentas, Nikos, Hultdin, Magnus, McKay, James D., Pott, Christiane, Vermeulen, Roel C. H., Langerak, Anton W.

Source: In Blood 19 October 2023 142(16):1399-1403

Extranodal marginal zone lymphoma clonotypes are detectable prior to eMZL diagnosis in tissue biopsies and peripheral blood of Sjögren's syndrome patients through immunogenetics.

Authors: Kolijn, P. Martijn, Huijser, Erika, Wahadat, M. Javad, van Helden-Meeuwsen, Cornelia G., van Daele, Paul L. A., Brkic, Zana, Rijntjes, Jos, Hebeda, Konnie M., Groenen, Patricia J. T. A., Versnel, Marjan A., Thurlings, Rogier M., Langerak, Anton W.

Source: Frontiers in Oncology; 4/23/2023, Vol. 13, p1-10, 10p

Subject Terms: SJOGREN'S syndrome, MUCOSA-associated lymphoid tissue lymphoma, MONONUCLEAR leukocytes, SEZARY syndrome, IMMUNOGENETICS, IMMUNOGLOBULIN heavy chains

T and NK Cells in IL2RG-Deficient Patient 50 Years After Hematopoietic Stem Cell Transplantation.

Authors: Melsen, Janine E., van Ostaijen-ten Dam, Monique M., van den Akker, Erik B., Welters, Marij J. P., Heezen, Kim C., Pico-Knijnenburg, Ingrid, Kolijn, P. Martijn, Bredius, Robbert G. M., van Doorn, Remco, Langerak, Anton W., Schilham, Marco W., Lankester, Arjan C.

Source: Journal of Clinical Immunology; Aug2022, Vol. 42 Issue 6, p1205-1222, 18p

Subject Terms: HEMATOPOIETIC stem cell transplantation, KILLER cells, T cells, BLOOD cells, STEM cells

TRB sequences targeting ORF1a/b are associated with disease severity in hospitalized COVID‐19 patients.

Authors: Assmann, Jorn L.J.C., Kolijn, P. Martijn, Schrijver, Benjamin, van Gammeren, Adriaan J., Loth, Daan W., Ermens, Ton A.A.M., Dik, Willem A., van der Velden, Vincent H.J., Langerak, Anton W.

Source: Journal of Leukocyte Biology; Jan2022, Vol. 111 Issue 1, p283-289, 7p

Subject Terms: COVID-19, T cell receptors, HOSPITAL patients, AMINO acid sequence, EPSTEIN-Barr virus diseases

Consistent B Cell Receptor Immunoglobulin Features Between Siblings in Familial Chronic Lymphocytic Leukemia.

Authors: Kolijn, P. Martijn, Muggen, Alice F., Ljungström, Viktor, Agathangelidis, Andreas, Wolvers-Tettero, Ingrid L. M., Beverloo, H. Berna, Pál, Karol, Hengeveld, Paul J., Darzentas, Nikos, Hendriks, Rudi W., Dongen, Jacques J. M. van, Rosenquist, Richard, Langerak, Anton W.

Source: Frontiers in Oncology; 8/26/2021, Vol. 11, p1-11, 11p

Subject Terms: B cell receptors, CHRONIC lymphocytic leukemia, SOMATIC mutation, IMMUNOGLOBULIN receptors, GENETIC mutation, SIBLINGS, CHRONIC leukemia