Identification of late-stage tau accumulation using plasma phospho-tau217

Authors: Woo, Marcel S., Therriault, Joseph, Jonaitis, Erin M., Wilson, Rachael, Langhough, Rebecca E., Rahmouni, Nesrine, Benedet, Andrea Lessa, Ashton, Nicholas J., Tissot, Cécile, Lantero-Rodriguez, Juan, Macedo, Arthur C., Servaes, Stijn, Wang, Yi-Ting, Arias, Jaime Fernandez, Hosseini, Seyyed Ali, Betthauser, Tobey J., Lussier, Firoza Z., Hopewell, Robert, Triana-Baltzer, Gallen, Kolb, Hartmuth C., Jeromin, Andreas, Kobayashi, Eliane, Massarweh, Gassan, Friese, Manuel A., Klostranec, Jesse, Vilali, Paolo, Pascoal, Tharick A., Gauthier, Serge, Zetterberg, Henrik, Blennow, Kaj, Johnson, Sterling C., Rosa-Neto, Pedro

Source: In eBioMedicine November 2024 109

Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity

Authors: Zicha, Stephen, Bateman, Randall J., Shaw, Leslie M., Zetterberg, Henrik, Bannon, Anthony W., Horton, Wesley A., Baratta, Mike, Kolb, Hartmuth C., Dobler, Iwona, Mordashova, Yulia, Saad, Ziad S., Raunig, David L., Spanakis, Emmanouil (Manos), Li, Yan, Schindler, Suzanne E., Ferber, Kyle, Rubel, Carrie E., Martone, Robert L., Weber, Christopher J., Edelmayer, Rebecca M., Meyers, Emily A., Bollinger, James G., Rosenbaugh, Erin G., Potter, William Z.

Source: Alzheimer's & dementia. 19(3):956-966

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178048543.0x000001&indx=1&recIds=ETOCvdc_100178048543.0x000001

Replication study of plasma proteins relating to Alzheimer's pathology

Authors: Shi, Liu, Winchester, Laura M., Westwood, Sarah, Baird, Alison L., Anand, Sneha N., Buckley, Noel J, Hye, Abdul, Ashton, Nicholas J., Bos, Isabelle, Vos, Stephanie J. B., Kate, Mara ten, Scheltens, Philip, Teunissen, Charlotte E., Vandenberghe, Rik, Gabel, Silvy, Meersmans, Karen, Engelborghs, Sebastiaan, De Roeck, Ellen E., Sleegers, Kristel, Frisoni, Giovanni B., Blin, Olivier, Richardson, Jill C., Bordet, Régis, Molinuevo, José L., Rami, Lorena, Wallin, Anders, Kettunen, Petronella, Tsolaki, Magda, Verhey, Frans, Lléo, Alberto, Sala, Isabel, Popp, Julius, Peyratout, Gwendoline, Martinez‐Lage, Pablo, Tainta, Mikel, Johannsen, Peter, Freund‐Levi, Yvonne, Frölich, Lutz, Dobricic, Valerija, Legido‐Quigley, Cristina, Barkhof, Frederik, Andreasson, Ulf, Blennow, Kaj, Zetterberg, Henrik, Streffer, Johannes, Lill, Christina M., Bertram, Lars, Visser, Pieter Jelle, Kolb, Hartmuth C., Narayan, Vaibhav A., Lovestone, Simon, Nevado‐Holgado, Alejo J.

Source: Alzheimer's & dementia. 17(9):1452-1464

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139874955.0x000001&indx=1&recIds=ETOCvdc_100139874955.0x000001

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System, device and method for preparing tracers and transferring materials during radiosynthesis

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Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics

Authors: Lee, Chung-Cheng, Sui, Guodong, Elizarov, Arkadij, Shu, Chengyi Jenny, Shin, Young-Shik, Dooley, Alek N., Huang, Jiang, Daridon, Antoine, Wyatt, Paul, Stout, David, Kolb, Hartmuth C., Witte, Owen N., Satyamurthy, Nagichettiar, Heath, James R., Phelps, Michael E., Quake, Stephen R., Tseng, Hsian-Rong

Source: Science, 2005 Dec . 310(5755), 1793-1796.

Access URL: https://www.jstor.org/stable/3843010

Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of ^1^8F-JNJ-64413739, a PET Radioligand for P2X7 Receptors

Authors: Kolb, Hartmuth C., Barret, Olivier, Bhattacharya, Anindya, Chen, Gang, Constantinescu, Cristian, Huang, Chaofeng, Letavic, Michael, Tamagnan, Gilles, Xia, Chunfang A., Zhang, Wei

Source: Journal of nuclear medicine. 60(8):1154-1159

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621131290&indx=1&recIds=ETOCRN621131290

Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum

Authors: Doré, Vincent, Doecke, James D., Saad, Ziad S., Triana‐Baltzer, Gallen, Slemmon, Randy, Krishnadas, Natasha, Bourgeat, Pierrick, Huang, Kun, Burnham, Samantha, Fowler, Christopher, Rainey‐Smith, Stephanie R., Bush, Ashley I., Ward, Larry, Robertson, Jo, Martins, Ralph N., Masters, Colin L., Villemagne, Victor L., Fripp, Jurgen, Kolb, Hartmuth C., Rowe, Christopher C.

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191267888.0x000001&indx=1&recIds=ETOCvdc_100191267888.0x000001

A head‐to‐head comparison of plasma phosphorylated tau assays in the real‐world memory clinic

Authors: Suárez‐Calvet, Marc, Ashton, Nicholas J., Puig‐Pijoan, Albert, Milà‐Alomà, Marta, Fernández‐Lebrero, Aida, García‐Escobar, Greta, González‐Ortiz, Fernándo, Kac, Przemyslaw Radoslaw, Brum, Wagner Scheeren, Benedet, Andréa Lessa, Rodriguez, Juan Lantero, Day, Theresa A., Dage, Jeffrey L., Vanbrabant, Jeroen, Stoops, Erik, Vanmechelen, Eugeen, Triana‐Baltzer, Gallen, Moughadam, Setareh, Kolb, Hartmuth C., Ortiz‐Romero, Paula, Karikari, Thomas K, Minguillón, Carolina, Sánchez, Juan José Hernández, Navalpotro‐Gómez, Irene, Grau‐Rivera, Oriol, Manero, Rosa María, Puente‐Periz, Víctor, de la Torre, Rafael, Roquer, Jaume, Zetterberg, Henrik, Blennow, Kaj

Source: Alzheimer's & dementia. 18(6)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176980950.0x000001&indx=1&recIds=ETOCvdc_100176980950.0x000001

Freeze-Frame Inhibitor Captures Acetylcholinesterase in a Unique Conformation

Authors: Bourne, Yves, Kolb, Hartmuth C., Radić, Zoran, Sharpless, K. Barry, Taylor, Palmer, Marchot, Pascale

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Feb 01. 101(6), 1449-1454.

Access URL: https://www.jstor.org/stable/3371209

Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's disease.

Authors: Sanchez-Rodriguez, Lazaro M., Bezgin, Gleb, Carbonell, Felix, Therriault, Joseph, Fernandez-Arias, Jaime, Servaes, Stijn, Rahmouni, Nesrine, Tissot, Cécile, Stevenson, Jenna, Karikari, Thomas K., Ashton, Nicholas J., Benedet, Andréa L., Zetterberg, Henrik, Blennow, Kaj, Triana-Baltzer, Gallen, Kolb, Hartmuth C., Rosa-Neto, Pedro, Iturria-Medina, Yasser

Source: Communications Biology; 5/4/2024, Vol. 7 Issue 1, p1-13, 13p

Subject Terms: NEUROFIBRILLARY tangles, ALZHEIMER'S disease, TAU proteins, VOXEL-based morphometry, CEREBRAL atrophy, FUNCTIONAL magnetic resonance imaging, GRAY matter (Nerve tissue), ALPHA rhythm

Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability

Authors: Hugenberg, Verena, Hermann, Sven, Galla, Fabian, Schäfers, Michael, Wünsch, Bernhard, Kolb, Hartmuth C., Szardenings, Katrin, Lebedev, Artem, Walsh, Joseph C., Mocharla, Vani P., Gangadharmath, Umesh B., Kopka, Klaus, Wagner, Stefan

Source: In Nuclear Medicine and Biology July 2016 43(7):424-437

PSMA imaging agents

Novel avenues of tau research.

Authors: Sexton, Claire E., Bitan, Gal, Bowles, Kathryn R., Brys, Miroslaw, Buée, Luc, Maina, Mahmoud Bukar, Clelland, Claire D., Cohen, Ann D., Crary, John F., Dage, Jeffrey L., Diaz, Kristophe, Frost, Bess, Gan, Li, Goate, Alison M, Golbe, Lawrence I., Hansson, Oskar, Karch, Celeste M., Kolb, Hartmuth C., La Joie, Renaud, Lee, Suzee E.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Mar2024, Vol. 20 Issue 3, p2240-2261, 22p

Plasma pTau‐217 and N‐terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid‐β positive individuals.

Authors: Woo, Marcel S., Tissot, Cécile, Lantero‐Rodriguez, Juan, Snellman, Anniina, Therriault, Joseph, Rahmouni, Nesrine, Macedo, Arthur C., Servaes, Stijn, Wang, Yi‐Ting, Arias, Jaime Fernandez, Hosseini, Seyyed Ali, Chamoun, Mira, Lussier, Firoza Z., Benedet, Andrea L., Ashton, Nicholas J., Karikari, Thomas K., Triana‐Baltzer, Gallen, Kolb, Hartmuth C., Stevenson, Jenna, Mayer, Christina

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Feb2024, Vol. 20 Issue 2, p1166-1174, 9p

Plasma phosphorylated tau‐217 exhibits sex‐specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.

Authors: Saloner, Rowan, VandeVrede, Lawren, Asken, Breton M., Paolillo, Emily W., Gontrum, Eva Q., Wolf, Amy, Lario‐Lago, Argentina, Milà‐Alomà, Marta, Triana‐Baltzer, Gallen, Kolb, Hartmuth C., Dubal, Dena B., Rabinovici, Gil D., Miller, Bruce L., Boxer, Adam L., Casaletto, Kaitlin B., Kramer, Joel H.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jan2024, Vol. 20 Issue 1, p376-387, 12p

Development and validation of a high‐sensitivity assay for measuring p217+tau in plasma

Authors: Triana‐Baltzer, Gallen, Moughadam, Setareh, Slemmon, Randy, Van Kolen, Kristof, Theunis, Clara, Mercken, Marc, Kolb, Hartmuth C.

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140925115.0x000001&indx=1&recIds=ETOCvdc_100140925115.0x000001

Comparative analytical performance of multiple plasma amyloid‐beta assays and their relationship to amyloid PET

Authors: Zicha, Stephen, Bateman, Randall J., Shaw, Leslie M., Bannon, Anthony W., Zetterberg, Henrik, Horton, Wesley A., Baratta, Michael, Kolb, Hartmuth C., Dobler, Iwona, Wang, Wenting, Raunig, David L., Saad, Ziad S., Mordashova, Yulia, Li, Yan, Bjorklund, Nicole L., Edelmayer, Rebecca M., Martone, Robert L., Rubel, Carrie E., Mawuenyega, Kwasi G., Bollinger, James G., Weber, Christopher J., Meyers, Emily A., Potter, William Z.

Source: Alzheimer's & dementia. 17(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138978462.0x000001&indx=1&recIds=ETOCvdc_100138978462.0x000001

Plasma p217+tau concordance with 18F‐NAV4694 beta‐amyloid and 18F‐MK6240 tau PET in mild Alzheimer's disease and cognitively unimpaired participants in the AIBL/ADNeT cohort

Authors: Rowe, Christopher C., Doecke, James D., Saad, Ziad S., Triana‐Baltzer, Gallen, Slemmon, J. Randall, Krishnadas, Natasha, Fowler, Christopher J., Rainey‐Smith, Stephanie R., Ward, Larry, Robertson, Joanne, Martins, Ralph N., Fripp, Jurgen, Masters, Colin L., Villemagne, Victor L., Kolb, Hartmuth C., Dore, Vincent

Source: Alzheimer's & dementia. 17(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138978508.0x000001&indx=1&recIds=ETOCvdc_100138978508.0x000001