Absence of PRCD Leads to Dysregulation in Lipid Homeostasis Resulting in Disorganization of Photoreceptor Outer Segment Structure
Retinal degeneration (19th international symposium)

Authors: Motipally, Sree I., Kolandaivelu, Saravanan

Source: Advances in experimental medicine and biology. 1415:389-394

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Aberrant lipid accumulation and retinal pigment epithelium dysfunction in PRCD-deficient mice

Authors: Motipally, Sree I., Kolson, Douglas R., Guan, Tongju, Kolandaivelu, Saravanan

Source: In Experimental Eye Research September 2024 246

Loss of MPC1 reprograms retinal metabolism to impair visual function

Authors: Grenell, Allison, Wang, Yekai, Yam, Michelle, Swarup, Aditi, Dilan, Tanya L., Hauer, Allison, Linton, Jonathan D., Philp, Nancy J., Gregor, Elizabeth, Zhu, Siyan, Shi, Quan, Murphy, Joseph, Guan, Tongju, Lohner, Daniel, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan, Goldberg, Andrew F. X., Hurley, James B., Dua, Jianhai

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb . 116(9), 3530-3535.

Access URL: https://www.jstor.org/stable/26672100

ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments

Authors: Dilan, Tanya L., Moye, Abigail R., Salido, Ezequiel M., Saravanan, Thamaraiselvi, Kolandaivelu, Saravanan, Goldberg, Andrew F. X., Ramamurthy, Visvanathan

Source: Journal of neuroscience. 39(8):1347-1364

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Palmitoylation of Progressive Rod-Cone Degeneration (PRCD) Regulates Protein Stability and Localization

Authors: Murphy, Joseph, Kolandaivelu, Saravanan

Source: In Journal of Biological Chemistry 28 October 2016 291(44):23036-23046

Analysis of Alternative Pre-RNA Splicing in the Mouse Retina Using a Fluorescent Reporter

Authors: Murphy, Daniel, Kolandaivelu, Saravanan, Ramamurthy, Visvanthan, Stoilov, Peter

Source: Methods in molecular biology. 1421:269-286

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Cardiac Mitochondrial Dysfunction in Ulcerative Colitis Mice Measured Using Electron Paramagnetic Resonance Spectroscopy

Authors: Velayutham, Murugesan, Brooks, Sydney, Kolandaivelu, Saravanan, Khramtsov, Valery, Rajendran, Vazhaikkurichi, Kupec, Justin

Source: In Free Radical Biology and Medicine 1 November 2024 224 Supplement 1:S77-S77

Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells

Authors: Majumder, Anurima, Pahlberg, Johan, Boyd, Kimberly K., Kerov, Vasily, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan, Sampath, Alapakkam P., Artemyev, Nikolai O.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jul . 110(30), 12468-12473.

Access URL: https://www.jstor.org/stable/42712614

RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments

Authors: Christiansen, Jeffrey R., Kolandaivelu, Saravanan, Bergo, Martin O., Ramamurthy, Visvanathan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 May . 108(21), 8862-8866.

Access URL: https://www.jstor.org/stable/25831043

Rod Phosphodiesterase-6 (PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic Subunit

Authors: Kolandaivelu, Saravanan, Chang, Bo, Ramamurthy, Visvanathan

Source: In Journal of Biological Chemistry 23 September 2011 286(38):33252-33259

AIPL1, a Protein Associated with Childhood Blindness, Interacts with α-Subunit of Rod Phosphodiesterase (PDE6) and Is Essential for Its Proper Assembly

Authors: Kolandaivelu, Saravanan, Huang, Jing, Hurley, James B., Ramamurthy, Visvanathan

Source: In Journal of Biological Chemistry 6 November 2009 284(45):30853-30861

R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization.

Authors: Myers, Boyden, Sechrest, Emily R., Hamner, Gabrielle, Motipally, Sree I., Murphy, Joseph, Kolandaivelu, Saravanan

Source: International Journal of Molecular Sciences; Sep2022, Vol. 23 Issue 18, pN.PAG-N.PAG, 16p

Subject Terms: PHOTORECEPTORS, ISOPRENYLATION, RETINITIS pigmentosa, PROTEINS, PROTEIN stability, PALMITOYLATION, RHODOPSIN

Nuclear NAD⁺-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons.

Authors: Sokolov, David, Sechrest, Emily R., Yekai Wang, Nevin, Connor, Jianhai Du, Kolandaivelu, Saravanan

Source: eLife; 1/12/2022, p1-26, 26p

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A photoreceptor specific splicing program confines the phenotype of a genetic mutation
Eurkaryotic mRNA processing (Meeting)

Authors: Murphy, Daniel P., Singh, Ratnesh, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan, Stoilov, Peter

Source: Abstracts of papers presented at the ... meeting on eukaryotic mRNA processing. 2015:151-151

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Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits.

Authors: Deng, Wen-Tao, Kolandaivelu, Saravanan, Dinculescu, Astra, Li, Jie, Zhu, Ping, Chiodo, Vince A., Ramamurthy, Visvanathan, Hauswirth, William W.

Source: Frontiers in Molecular Neuroscience; 7/9/2018, pN.PAG-N.PAG, 10p

Subject Terms: PHOSPHODIESTERASES, CYCLIC guanylic acid, ADENO-associated virus

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