Activity of (η6-arene)dichloridoruthenium(II) complexes with antifungal imidazolyl-based ligands against Toxoplasma gondii and Leishmania major

Authors: Al Nasr, Ibrahim S., Daoud, Ismail, Koko, Waleed S., Khan, Tariq A., Schobert, Rainer, Ben Said, Ridha, Amdouni, Noureddine, Rahali, Seyfeddine, Al-Ghamdi, Ali O., Biersack, Bernhard

Source: In Inorganica Chimica Acta 24 May 2024 565

Bridged NHC-Pd(II) complexes: Synthesis, DFT calculations, molecular docking, and investigation of catalytic and biological activities

Authors: Fırat, Tuba, Buğday, Nesrin, Yaşar, Şeyma, Boulebd, Houssem, Mansour, Lamjed, Koko, Waleed S., Hamdi, Naceur, Yaşar, Sedat

Source: In Journal of Organometallic Chemistry 1 May 2024 1011

Novel ruthenium(ii) N-heterocyclic carbene complexes: Synthesis, characterization, and evaluation of their biological activities

Authors: Jawhari Ahmed Hussain, Amri Nasser, Mukhrish Yousef E., Gatri Rafik, Özdemir Ismail, Gürbüz Nevin, Mansour Lamjed, Koko Waleed S., Hamdi Naceur

Source: Main Group Metal Chemistry, Vol 46, Iss 1, Pp 1046-1049 (2023)

Subject Terms: biological activity, benzimidazolium salts, ruthenium complexes, silver complexes, hct-116, hepg-2, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2191-0219

Access URL: https://doaj.org/article/201a0f4d634b448481cc25f7ace0f374

Versatile anti-infective properties of pyrido- and dihydropyrido[2,3-d]pyrimidine-based compounds

Authors: Al Nasr, Ibrahim S., Corona, Angela, Koko, Waleed S., Khan, Tariq A., Ben Said, Ridha, Daoud, Ismail, Rahali, Seyfeddine, Tramontano, Enzo, Schobert, Rainer, Amdouni, Noureddine, Biersack, Bernhard

Source: In Bioorganic & Medicinal Chemistry 15 July 2023 90

Synthesis, characterization and in vitro bioactivity studies of isoindolin‐1‐3‐phosophonate compounds

Authors: Jelali, Hamida, Al Nasr, Ibrahim S., Koko, Waleed S., Khan, Tariq A., Deniau, Eric, Sauthier, Mathieu, Alresheedi, Faisal, Hamdi, Naceur

Source: Journal of heterocyclic chemistry. 59(3):493-506

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144669718.0x000001&indx=1&recIds=ETOCvdc_100144669718.0x000001

Design, Hemisynthesis, Characterization, Molecular Docking, and Dynamics Evaluation of Novel Totarol‐1,2,3‐Triazole Derivatives as Leishmaniasis and Toxoplasmosis Agents.

Authors: Boualli, Ayoub, Laamari, Yassine, Bimoussa, Abdoullah, Ejaz, Syeda Abida, Attaullah, Hafiz Muhammad, Riahi, Abdelkhalek, Robert, Anthony, Daran, Jean‐Claude, Al Nasr, Ibrahim S., Koko, Waleed S., Khan, Tariq A., Biersack, Bernhard, Auhmani, Aziz, Itto, My Youssef Ait

Source: Chemical Biology & Drug Design; Feb2025, Vol. 105 Issue 2, p1-27, 27p

Identification of a New Pentafluorosulfanyl-Substituted Chalcone with Activity Against Hepatoma and Human Parasites.

Authors: Viperino, Alessandra, Höpfner, Michael, Edel, Nicole, Al Nasr, Ibrahim S., Koko, Waleed S., Khan, Tariq A., Ben Abdelmalek, Imen, Schobert, Rainer, Biersack, Bernhard, Nitzsche, Bianca

Source: Pharmaceuticals (14248247); Jan2025, Vol. 18 Issue 1, p50, 16p

Subject Terms: PROTOZOAN diseases, LIVER cancer, LIVER cells, TOXOPLASMA gondii, ANTIPARASITIC agents

p-Trifluoromethyl- and p-pentafluorothio-substituted curcuminoids of the 2,6-di[(E)-benzylidene)]cycloalkanone type: Syntheses and activities against Leishmania major and Toxoplasma gondii parasites

Authors: Al Nasr, Ibrahim S., Hanachi, Riadh, Said, Ridha B., Rahali, Seyfeddine, Tangour, Bahoueddine, Abdelwahab, Siddig I., Farasani, Abdullah, M. E. Taha, Manal, Bidwai, Anil, Koko, Waleed S., Khan, Tariq A., Schobert, Rainer, Biersack, Bernhard

Source: In Bioorganic Chemistry September 2021 114

Old Dogs with New Tricks: Antiparasitic Potential of Structurally Diverse 5-Nitrofuran and 5-Nitrothiophene Imines and Acyl Hydrazones.

Authors: Al Nasr, Ibrahim S.^1,2 (AUTHOR) insar@qu.edu.sa, Koko, Waleed S.² (AUTHOR), Khan, Tariq A.³ (AUTHOR) sirtariqayub@gmail.com, Schobert, Rainer⁴ (AUTHOR) rainer.schobert@uni-bayreuth.de, Biersack, Bernhard⁴ (AUTHOR) bernhard.biersack@yahoo.com

Source: Scientia Pharmaceutica. Sep2023, Vol. 91 Issue 3, p44. 14p.

Subject Terms: *IMINES, *HYDRAZONES, *LEISHMANIA major, *NEPHROTOXICOLOGY, *DOGS

Antiparasitic Activities of Acyl Hydrazones from Cinnamaldehydes and Structurally Related Fragrances.

Authors: Al Nasr, Ibrahim S., Koko, Waleed S., Khan, Tariq A., Schobert, Rainer, Biersack, Bernhard

Source: Antibiotics (2079-6382); Dec2024, Vol. 13 Issue 12, p1114, 16p

Subject Terms: PROTOZOAN diseases, TOXOPLASMA gondii, LEISHMANIA major, TOXOPLASMOSIS, LEISHMANIASIS

Therapeutic Potential of Aryl Sulfonamides: Synthesis, Antiproliferative, Antioxidant, Antiparasitic and Molecular Docking Studies.

Authors: Tambat, Nazia, Tambe, Pranav, Sheikh, Kounsar N., Shaikh, Amin, Saleh, Khaled M., AlSakhen, Mai F., Kanaan, Sana I., Al Nasr, Ibrahim S., Koko, Waleed S., Khan, Tariq A., Schobert, Rainer, Biersack, Bernhard, Tahtamouni, Lubna H., Ahmed, Khursheed

Source: ChemistrySelect; 11/4/2024, Vol. 9 Issue 41, p1-15, 15p

Subject Terms: HYDROCORTISONE, THYMIDYLATE synthase, ANTIPARASITIC agents, MOLECULAR docking, LEISHMANIA major, PHENOL oxidase

Antiparasitic activities of bimetallic N‐heterocyclic carbene gold(I) complexes with ferrocene ligands: Relevance of chlorido and phosphino ligands

Authors: Al Nasr, Ibrahim S., Weise, Markus, Koko, Waleed S., Khan, Tariq A., Schobert, Rainer, Biersack, Bernhard

Source: Applied organometallic chemistry. 37(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183594778.0x000001&indx=1&recIds=ETOCvdc_100183594778.0x000001

Versatile anti-infective properties of pyrido- and dihydropyrido[2, 3-d]pyrimidine-based compounds

Authors: Al Nasr, Ibrahim S., Corona, Angela, Koko, Waleed S., Khan, Tariq A., Ben Said, Ridha, Daoud, Ismail, Rahali, Seyfeddine, Tramontano, Enzo, Schobert, Rainer, Amdouni, Noureddine, Biersack, Bernhard

Source: Bioorganic & medicinal chemistry. 90

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193585764.0x000001&indx=1&recIds=ETOCvdc_100193585764.0x000001

Regiospecific Reduction of 4, 6‐Dinitrobenzimidazoles: Synthesis, Characterization, and Biological Evaluation

Authors: Abouelhaoul, El Alami, El Kihel, Abdellatif, Ahbala, Mustapha, Sdassi, Hamid, Köhler, Leonhard H. F., Bauchat, Patrick, Roisnel, Thierry, Khan, Tariq A., Al Nasr, Ibrahim S., Koko, Waleed S., Schobert, Rainer, Biersack, Bernhard

Source: Chemistry & biodiversity. 20(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189688167.0x000001&indx=1&recIds=ETOCvdc_100189688167.0x000001

Evaluation of the Antiparasitic and Antifungal Activities of Synthetic Piperlongumine‐Type Cinnamide Derivatives: Booster Effect by Halogen Substituents

Authors: Khan, Tariq A., Al Nasr, Ibrahim S., Koko, Waleed S., Ma, Jingyi, Eckert, Simon, Brehm, Lucas, Ben Said, Ridha, Daoud, Ismail, Hanachi, Riadh, Rahali, Seyfeddine, Sande, Wendy W. J., Ersfeld, Klaus, Schobert, Rainer, Biersack, Bernhard

Source: ChemMedChem. 18(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185949205.0x000001&indx=1&recIds=ETOCvdc_100185949205.0x000001

Evaluation of Ruthenium(II) N -Heterocyclic Carbene Complexes as Enzymatic Inhibitory Agents with Antioxidant, Antimicrobial, Antiparasitical and Antiproliferative Activity.

Authors: Al Nasr, Ibrahim S.^1,2 (AUTHOR), Koko, Waleed S.² (AUTHOR), Khan, Tariq A.³ (AUTHOR), Gürbüz, Nevin^4,5 (AUTHOR), Özdemir, Ismail^4,5 (AUTHOR), Hamdi, Naceur⁶ (AUTHOR) 141301@qu.edu.sa

Source: Molecules. Feb2023, Vol. 28 Issue 3, p1359. 14p.

Subject Terms: *ANTIPARASITIC agents, *RUTHENIUM, *DRUG discovery, *LEISHMANIA major, *RUTHENIUM compounds, *ELEMENTAL analysis, *QUINAZOLINONES

Anticancer, antimicrobial and antiparasitical activities of copper(I) complexes based on N-heterocyclic carbene (NHC) ligands bearing aryl substituents

Authors: Touj, Nedra, Nasr, Ibrahim S. Al, Koko, Waleed S., Khan, Tariq A., Özdemir, Ismail, Yasar, Sedat, Mansour, Lamjed, Alresheedi, Faisal, Hamdi, Naceur

Source: Journal of coordination chemistry. 73(20-22):2889-2905

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121661791.0x000001&indx=1&recIds=ETOCvdc_100121661791.0x000001

Ethanolic Extract of Mangifera indica Protects against CCl4‐Induced Hepatotoxicity via Antioxidant Capabilities in Albino Rats.

Authors: Kabbashi, Ahmed Saeed, Eltawaty, Salwa Abdulla, Ismail, Amar Mohamed, Elshikh, Ahmed Abdelhhafiz, Alrasheid, Ayat Ahmed, Elmahi, Rawan Ahmed, Koko, Waleed S., Osman, Elbadri Elamin, sucharitakul, Phuping

Source: Journal of Toxicology; 8/27/2024, Vol. 2024, p1-8, 8p

Subject Terms: MANGO, ORAL drug administration, ALANINE aminotransferase, ASPARTATE aminotransferase, BLOOD sugar, CARBON tetrachloride

Synthesis, DFT calculations, and investigation of catalytic and biological activities of back‐bond functionalized re‐NHC‐Cu complexes.

Authors: Yagmurlu, Ayse, Buğday, Nesrin, Yaşar, Şeyma, Boulebd, Houssem, Mansour, Lamjed, Koko, Waleed S., Hamdi, Naceur, Yaşar, Sedat

Source: Applied Organometallic Chemistry; Jul2024, Vol. 38 Issue 7, p1-16, 16p

Subject Terms: CATALYTIC activity, RING formation (Chemistry), MOLECULAR shapes, DENSITY functional theory, CATALYST synthesis, HEPATOCELLULAR carcinoma, IRINOTECAN, COPPER compounds

In vitro activity of some natural honeys against Entamoeba histolytica and Giardia lamblia trophozoites

Authors: Mohammed, Seif Eldin A., Kabbashi, Ahmed S., Koko, Waleed S., Ansari, Mohammad Javed, Adgaba, Nuru, Al-Ghamdi, Ahmad

Source: In Saudi Journal of Biological Sciences February 2019 26(2):238-243