Expression Analysis of Heavy-Chain-Only Antibodies in Cloudy Catshark and Japanese Bullhead Shark

Authors: Reo Uemura, Susumu Tanimura, Nao Yamaguchi, Ryuichi Kuroiwa, Gabriel Takashi Andrés Tsutsumi, Toshiaki Fujikawa, Kiyoshi Soyano, Kohsuke Takeda, Yoshimasa Tanaka

Source: Marine Drugs, Vol 23, Iss 1, p 28 (2025)

Subject Terms: cloudy catshark, heavy-chain-only antibody, immunoglobulin new antigen receptor, Japanese bullhead shark, VNAR-domain antibody, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/23/1/28; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/f7163ffaaaf948f2bb4ce99b47e9a913

Marine-derived microbes and molecules for drug discovery

Authors: Yoshimasa Tanaka, Megumi Nishikawa, Kaho Kamisaki, Saki Hachiya, Moeka Nakamura, Takahiro Kuwazuru, Susumu Tanimura, Kiyoshi Soyano, Kohsuke Takeda

Source: Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-12 (2022)

Subject Terms: Autoimmune disease, Autoinflammatory disease, Biologic, Conventional drug, Marine microbe, Monoclonal antibody, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/1880-8190

Access URL: https://doaj.org/article/c5173ffe1e174398bc8f7647c6db1483

Identification of surfactin as an anti-severe fever with thrombocytopenia syndrome virus multi-target compound extracted from the culture broth of marine microbes

Authors: Shuzo Urata, Jun Takouda, Yoshihiro Watanabe, Miako Sakaguchi, Yasuteru Sakurai, Yuki Inahashi, Masato Iwatsuki, Jiro Yasuda, Yoshimasa Tanaka, Kohsuke Takeda

Source: Frontiers in Virology, Vol 2 (2023)

Subject Terms: severe fever with thrombocytopenia syndrome virus (SFTSV), anti-SFTSV compound, marine microbes, surfactin, screening, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fviro.2022.1064265/full; https://doaj.org/toc/2673-818X

Access URL: https://doaj.org/article/06aec09f7db946c2aff01e198ed72a0e

ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

Authors: Takashi Sugiyama, Naoya Murao, Hisae Kadowaki, Keizo Takao, Tsuyoshi Miyakawa, Yosuke Matsushita, Toyomasa Katagiri, Akira Futatsugi, Yohei Shinmyo, Hiroshi Kawasaki, Juro Sakai, Kazutaka Shiomi, Masamitsu Nakazato, Kohsuke Takeda, Katsuhiko Mikoshiba, Hidde L. Ploegh, Hidenori Ichijo, Hideki Nishitoh

Source: iScience, Vol 24, Iss 7, Pp 102758- (2021)

Subject Terms: Biological sciences, Neuroscience, Molecular neuroscience, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004221007264; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/b69667e8cdc0451bb9c8130fc2b00445

ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation

Authors: Tianli Zhang, Hiroyasu Tsutsuki, Waliul Islam, Katsuhiko Ono, Kohsuke Takeda, Takaaki Akaike, Tomohiro Sawa

Source: Redox Biology, Vol 41, Iss , Pp 101930- (2021)

Subject Terms: NLRP3 inflammasome, Glutathione, ATP, GSH efflux, Reactive oxygen species, Redox regulation, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721000781; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/530f6f5d9fca453385eb15653b28e95b

ASK1 signalling regulates brown and beige adipocyte function

Authors: Kazuki Hattori, Isao Naguro, Kohki Okabe, Takashi Funatsu, Shotaro Furutani, Kohsuke Takeda, Hidenori Ichijo

Source: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ce51b10276424997a93a5ef2e239f66a

The Ablation of Mitochondrial Protein Phosphatase Pgam5 Confers Resistance Against Metabolic Stress

Authors: Shiori Sekine, Akari Yao, Kazuki Hattori, Sho Sugawara, Isao Naguro, Masato Koike, Yasuo Uchiyama, Kohsuke Takeda, Hidenori Ichijo

Source: EBioMedicine, Vol 5, Iss C, Pp 82-92 (2016)

Subject Terms: Mitochondria, Stress response, Metabolic stress, Obesity, FGF21, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396416300275; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/ec3de6283067488f9644f2dd3cd16556

Prevention of apoptosis by mitochondrial phosphatase PGAM5 in the mushroom body is crucial for heat shock resistance in Drosophila melanogaster.

Authors: Yosuke Ishida, Yusuke Sekine, Haruka Oguchi, Takahiro Chihara, Masayuki Miura, Hidenori Ichijo, Kohsuke Takeda

Source: PLoS ONE, Vol 7, Iss 2, p e30265 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3274544?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f04e23ec59dd4864b041caea19e9193b

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Authors: Yuzuru Imai, Tomoko Kanao, Tomoyo Sawada, Yoshito Kobayashi, Yasuhiro Moriwaki, Yosuke Ishida, Kohsuke Takeda, Hidenori Ichijo, Bingwei Lu, Ryosuke Takahashi

Source: PLoS Genetics, Vol 6, Iss 12, p e1001229 (2010)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2996328?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/7b5f21c360034393b1c9a28a38dd3445

ERK signalling as a regulator of cell motility.

Authors: Susumu Tanimura¹ tani1211@nagasaki-u.ac.jp, Kohsuke Takeda¹

Source: Journal of Biochemistry. Sep2017, Vol. 162 Issue 3, p145-154. 10p.

Subject Terms: *CELL motility, *EXTRACELLULAR signal-regulated kinases, *CELL-matrix adhesions, *PHOSPHORYLATION, *RIBOSOMAL proteins, *GENETIC regulation, *CANCER cell proliferation

ASK1 signaling regulates phase-specific glial interactions during neuroinflammation.

Authors: Xiaoli Guo, Atsuko Kimura, Kazuhiko Namekata, Chikako Harada, Nobutaka Arai, Kohsuke Takeda, Hidenori Ichijo, Takayuki Harada

Source: Proceedings of the National Academy of Sciences of the United States of America; 2/8/2022, Vol. 119 Issue 6, p1-12, 12p

Subject Terms: MITOGEN-activated protein kinases, NEUROINFLAMMATION, NEUROGLIA, DENDRITIC cells, KNOCKOUT mice, CURCUMIN

Lead Optimization of Influenza Virus RNA Polymerase Inhibitors Targeting PA-PB1 Interaction.

Authors: Satoshi Mizuta, Hiroki Otaki, Takeshi Ishikawa, Makau, Nzembi, Juliann, Tomoko Yamaguchi, Takuya Fujimoto, Nobuyuki Takakura, Nobuki Sakauchi, Shuji Kitamura, Hikaru Nono, Ryota Nishi, Yoshimasa Tanaka, Kohsuke Takeda, Noriyuki Nishida, Ken Watanabe

Source: Journal of Medicinal Chemistry; 1/13/2022, Vol. 65 Issue 1, p369-385, 17p

Mitochondrial function is required for extracellular ATP-induced NLRP3 inflammasome activation.

Authors: Daichi Sadatomi, Kazutaka Nakashioya, Sayaka Mamiya, Shino Honda, Yuka Kameyama, Yasuo Yamamura, Susumu Tanimura, Kohsuke Takeda

Source: Journal of Biochemistry; Jun2017, Vol. 161 Issue 6, p503-512, 10p

Subject Terms: ADENOSINE triphosphate, INFLAMMASOMES, CYTOKINES, INTERLEUKINS, MACROPHAGES

ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips.

Authors: Susumu Tanimura^1,2, ani1211@nagasaki-u.ac.jp, Junya Hashizume¹, Naoya Arichika¹, Kazushi Watanabe¹, Kaname Ohyama^2,3, Kohsuke Takeda¹, Michiaki Kohno¹, kohnom@nagasaki-u.ac.jp

Source: Journal of Cell Biology; 8/15/2016, Vol. 214 Issue 4, p475-489, 15p

The ASK family kinases differentially mediate induction of type I interferon and apoptosis during the antiviral response.

Authors: Tomohiko Okazaki, Maiko Higuchi, Kohsuke Takeda, Kiyoko Iwatsuki-Horimoto, Maki Kiso, Makoto Miyagishi, Hideyuki Yanai, Atsushi Kato, Mitsutoshi Yoneyama, Takashi Fujita, Tadatsugu Taniguchi, Yoshihiro Kawaoka, Hidenori Ichijo, Yukiko Gotoh

Source: Science Signaling; 8/4/2015, Vol. 8 Issue 388, p1-12, 12p

Adipose-Derived Stem Cells Promote Proliferation, Migration, and Tube Formation of Lymphatic Endothelial Cells In Vitro by Secreting Lymphangiogenic Factors.

Authors: Kohsuke Takeda, Yoshihiro Sowa, Kenichi Nishino, Kyoko Itoh, Shinji Fushiki

Source: Annals of Plastic Surgery; Jun2015, Vol. 74 Issue 6, p728-736, 9p

The DEAH-Box RNA Helicase DHX15 Activates NF-κB and MAPK Signaling Downstream of MAVS During Antiviral Responses.

Authors: Kenta Mosallanejad, Yusuke Sekine, Seiko Ishikura-Kinoshita, Kazuo Kumagai, Tetsuo Nagano, Atsushi Matsuzawa, Kohsuke Takeda, Isao Naguro, Hidenori Ichijo

Source: Science Signaling; 4/29/2014, Vol. 7 Issue 323, p1-11, 11p

ASK1 promotes the contact hypersensitivity response through IL-17 production.

Authors: Junya Mizukami, Takehiro Sato, Camps, Montserrat, Ji, Hong, Rueckle, Thomas, Swinnen, Dominique, Ryoji Tsuboi, Kohsuke Takeda, Hidenori Ichijo

Source: Scientific Reports; 4/18/2014, p1-8, 8p

Subject Terms: CONTACT dermatitis, HAPTENS, SKIN inflammation, CELLULAR immunity, DELAYED hypersensitivity

Apoptosis Signaling Kinases: From Stress Response to Health Outcomes.

Authors: Kohsuke Takeda, Isao Naguro, Hideki Nishitoh, Atsushi Matsuzawa, Hidenori Ichijo

Source: Antioxidants & Redox Signaling. Aug2011, Vol. 15 Issue 3, p719-761. 43p.

Subject Terms: *APOPTOSIS, *PHYSIOLOGICAL stress, *HEALTH, *HOMEOSTASIS, *CYSTEINE proteinases, *PROTEIN kinases

This result is not displayed to guests.
Login for full access.