Liver X receptor regulation of thyrotropin-releasing hormone transcription in mouse hypothalamus is dependent on thyroid status.

Authors: Rym Ghaddab-Zroud, Isabelle Seugnet, Knut R Steffensen, Barbara A Demeneix, Marie-Stéphanie Clerget-Froidevaux

Source: PLoS ONE, Vol 9, Iss 9, p e106983 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4167690?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/71421671874c4583ab490b12c1e06d67

Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells.

Authors: Nicholes R Candelaria, Sridevi Addanki, Jine Zheng, Trang Nguyen-Vu, Husna Karaboga, Prasenjit Dey, Chiara Gabbi, Lise-Lotte Vedin, Ka Liu, Wanfu Wu, Philip K Jonsson, Jean Z Lin, Fei Su, Lakshmi Reddy Bollu, Sally E Hodges, Amy L McElhany, Mehdi A Issazadeh, William E Fisher, Michael M Ittmann, Knut R Steffensen, Jan-Åke Gustafsson, Chin-Yo Lin

Source: PLoS ONE, Vol 9, Iss 9, p e106289 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4153644?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4b766a328e044a598a76bfafa68f8a91

Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice.

Authors: Matteo Pedrelli, Padideh Davoodpour, Chiara Degirolamo, Monica Gomaraschi, Mark Graham, Alice Ossoli, Lilian Larsson, Laura Calabresi, Jan-Åke Gustafsson, Knut R Steffensen, Mats Eriksson, Paolo Parini

Source: PLoS ONE, Vol 9, Iss 4, p e93552 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093552&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/84f8dce4f8ea4df6a4d1616d2b236234

Myelin-derived lipids modulate macrophage activity by liver X receptor activation.

Authors: Jeroen F J Bogie, Silke Timmermans, Vân Anh Huynh-Thu, Alexandre Irrthum, Hubert J M Smeets, Jan-Åke Gustafsson, Knut R Steffensen, Monique Mulder, Piet Stinissen, Niels Hellings, Jerome J A Hendriks

Source: PLoS ONE, Vol 7, Iss 9, p e44998 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3440367?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/5aafb65e5a5b4dbea6049ae2cc79c7b5

Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

Authors: Karine H Hellemans, Jean-Claude Hannaert, Bart Denys, Knut R Steffensen, Cindy Raemdonck, Geert A Martens, Paul P Van Veldhoven, Jan-Ake Gustafsson, Daniel Pipeleers

Source: PLoS ONE, Vol 4, Iss 9, p e7266 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2746288?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/139ce2ea13384226bea0bc3ef4a7c07d

Reprogramming of the LXRα Transcriptome Sustains Macrophage Secondary Inflammatory Responses

Authors: Juan Vladimir de la Rosa, Carlos Tabraue, Zhiqiang Huang, Marta C. Orizaola, Patricia Martin‐Rodríguez, Knut R. Steffensen, Juan Manuel Zapata, Lisardo Boscá, Peter Tontonoz, Susana Alemany, Eckardt Treuter, Antonio Castrillo

Source: Advanced Science, Vol 11, Iss 20, Pp n/a-n/a (2024)

Subject Terms: gene expression, inflammation, macrophage, nuclear receptor LXR, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/0d64bc9760874725979011a9fec830ac

The oxysterol receptor LXR inhibits proliferation of human breast cancer cells.

Authors: Lise-Lotte Vedin, Sebastian A. Lewandowski, Paolo Parini, Jan-Åke Gustafsson, Knut R. Steffensen

Source: Carcinogenesis; Apr2009, Vol. 30 Issue 4, p575-579, 5p

Subject Terms: OXYSTEROLS, CELL receptors, BREAST cancer, CANCER cell proliferation, CHOLESTEROL, LIPID synthesis, RETINOBLASTOMA, PREVENTION

Activation of PPAR γ in colon tumor cell lines by oxidized metabolites of linoleic acid, endogenous ligands for PPAR γ.

Authors: Arthur W. Bull, Knut R. Steffensen, Jörg Leers, Joseph J. Rafter

Source: Carcinogenesis; 11/1/2003, Vol. 24 Issue 11, p1717-1722, 6p

Subject Terms: HORMONES, MESSENGER RNA, ENZYMES, METABOLISM

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Srebf1 Controls Midbrain Dopaminergic Neurogenesis

Authors: Enrique M. Toledo, Shanzheng Yang, Daniel Gyllborg, Kim E. van Wijk, Indranil Sinha, Manuel Varas-Godoy, Christopher L. Grigsby, Peter Lönnerberg, Saiful Islam, Knut R. Steffensen, Sten Linnarsson, Ernest Arenas

Source: Cell Reports, Vol 31, Iss 5, Pp - (2020)

Subject Terms: chromatin immunoprecipitation, single-cell RNA sequencing, radial glia, nuclear receptor, LXR, oxysterol, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720305507; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/f4229bb19bc34ba8985a4bcb466ddeea

Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Authors: Elien Wouters, Nienke M. de Wit, Jasmine Vanmol, Susanne M. A. van der Pol, Bert van het Hof, Daniela Sommer, Melanie Loix, Dirk Geerts, Jan Ake Gustafsson, Knut R. Steffensen, Tim Vanmierlo, Jeroen F. J. Bogie, Jerome J. A. Hendriks, Helga E. de Vries

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: blood-brain barrier, permeability, endothelium, liver X receptors, neuroinflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01811/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/56fc8933ec1142a69ee5c39bf8b09233

Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors

Authors: Raffaella Fontana, Laura Raccosta, Lucrezia Rovati, Knut R. Steffensen, Aida Paniccia, Tomas Jakobsson, Giulio Melloni, Alessandro Bandiera, Giorgia Mangili, Alice Bergamini, Daniela Maggioni, Claudio Doglioni, Roberto Crocchiolo, Marina Cella, Michela Mattioli, Cristina Battaglia, Marco Colonna, Vincenzo Russo

Source: OncoImmunology, Vol 8, Iss 3 (2019)

Subject Terms: lxr nuclear receptors, rar/rxr nuclear receptors, dendritic cells, trem-1, lung cancer, ovarian cancer, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/b7ba04724b654fa18c05bbb4d69059e9

Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity[S]

Authors: Christian Bindesbøll, Qiong Fan, Rikke C. Nørgaard, Laura MacPherson, Hai-Bin Ruan, Jing Wu, Thomas Å. Pedersen, Knut R. Steffensen, Xiaoyong Yang, Jason Matthews, Susanne Mandrup, Hilde I. Nebb, Line M. Grønning-Wang

Source: Journal of Lipid Research, Vol 56, Iss 4, Pp 771-785 (2015)

Subject Terms: lipid metabolism, insulin, glucose, carbohydrate responsive element-binding protein α, carbohydrate responsive element-binding protein β, chromatin immunoprecipitation, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520355607; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/ea74357040794890a9059321a49a7f5b

Anti-inflammatory nuclear receptor superfamily in multiple sclerosis patients from Sardinia and Sweden

Authors: Xuan Liu, Knut R. Steffensen, Alessandra Sanna, Giannina Arru, Maria Laura Fois, Giulio Rosati, Stefano Sotgiu, Hans Link, Jan-Åke Gustafsson, Yu-Min Huang

Source: Neurobiology of Disease, Vol 20, Iss 3, Pp 961-968 (2005)

Subject Terms: Multiple sclerosis, Liver X receptors, Estrogen receptors, Androgen receptor, Sardinia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S096999610500166X; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/6cd7cf10350e47708c07d953eac77667