Metabolic Acidosis Is Associated With an Accelerated Decline of Allograft Function in Pediatric Kidney Transplantation

Authors: Ariceta, Gema, Awan, Atif, Bakkaloğlu, Sevcan, Bonthuis, Marjolein, Robroeks, Charlotte Bootsma, Bouts, Antonia, Christian, Martin, Cornelissen, Marlies, Duzova, Ali, Esfandiar, Nasrin, Ghio, Luciana, Grenda, Ryszard, Guzzo, Isabella, Goni, Maria Herrero, Hogan, Julien, Hongsawong, Nattaphorn, Kanzelmeyer, Nele, Bayazit, Aysun Karabay, Aksoy, Gülşah Kaya, Knops, Noel, Kamphuis, Linda Koster, Erez, Daniella Levy, Lopez-Baez, Victor, Madrid, Alvaro, Marks, Stephen, Melk, Anette, Murer, Luisa, Pape, Lars, Peruzzi, Licia, Petrosyan, Edita, Preka, Evgenia, Printza, Nikoleta, Rachisan, Andreea Liana, Raes, Ann, Shenoy, Mohan, Soylemezoglu, Oguz, Strologo, Luca Dello, Teixeira, Ana, Topaloglu, Rezan, Weitz, Markus, Zieg, Jakub, Zlatanova, Galia, Patry, Christian, Harambat, Jerome, Ağbaş, Ayşe, Askiti, Varvara, Avramescu, Marina, Bacchetta, Justine, Bakkaloglu, Sevcan, Bontuis, Marjolein, Booth, Caroline, Dehoux, Laurene, Dizazzo, Giacomo, Drozdz, Dorota, Dursun, Ismail, Gessner, Michaela, Groothoff, Jaap, Guido, Giuliana, Klaus, Guenter, Koster-Kamphuis, Linda, Lalayiannis, Alexander, Leifheit-Nestler, Maren, Manish, Sinha, Matteucci, Chiara, Oh, Jun, Ozkaya, Ozan, Pietrement, Christine, Prytula, Agnieszka, Reusz, George, Schaefer, Franz, Schmitt, Claus Peter, Schön, Anne, Sever, Fatma Lale, Stabouli, Stella, Döven, Serra Sürmeli, Tondel, Camilla, Verrina, Enrico, Vidal, Enrico, Wallace, Dean, Arslan, Zainab, Bald, M., Fehrenbach, H., Haffner, D., Hansen, M., Hempel, C., John, U., Klaus, G., König, J., Lange-Sperandio, B., Müller, D., Oh, J., Pape, L., Pohl, M., Sauerstein, K., Schalk, G., Staude, H., Strotmann, P., Weber, L.T., Weitz, M., Berta, L., Heindl-Rusai, K., Shroff, Rukshana, van Gremberghe, Ineke, Krupka, Kai, Benetti, Elisa, Büyükkaragöz, Bahar, Kranz, Birgitta, Nalçacıoğlu, Hülya, Sellier-Leclerc, Anne-Laure, Tönshoff, Burkhard

Source: In Kidney International Reports June 2024 9(6):1684-1693

Renal outcome and plasma methylmalonic acid levels after isolated or combined liver or kidney transplantation in patients with methylmalonic acidemia: A multicenter analysis

Authors: Dello Strologo, Luca, Spada, Marco, Vici, Carlo Dionisi, Atti, Marta Ciofi Degli, Rheault, Michelle, Bjerre, Anna Kristina, Boyer, Olivia, Calvo, Pier Luigi, D'Antiga, Lorenzo, Harshman, Lyndsay A., Hörster, Friederike, Kölker, Stefan, Jahnukainen, Timo, Knops, Noël, Krug, Pauline, Krupka, Kai, Lee, Angela, Levtchenko, Elena, Marks, Stephen D., Stojanovic, Jelena, Martelli, Laura, Mazariegos, George, Montini, Giovanni, Shenoy, Mohan, Sidhu, Sangeet, Tangeras, Trine, Testa, Sara, Vijay, Suresh, Wac, Katarzyna, Wennberg, Lars, Concepcion, Waldo, Garbade, Sven F., Tönshoff, Burkhard

Source: In Molecular Genetics and Metabolism November 2022 137(3):265-272

Diagnostic and therapeutic management of vesico‐ureteral reflux in pediatric kidney transplantation—Results of an online survey on behalf of the European Society for Paediatric Nephrology

Authors: Zirngibl, Matthias, Buder, Kathrin, Luithle, Tobias, Tönshoff, Burkhard, Weitz, Marcus, Alonso‐Melgar, Ángel, Ariceta, Gema, Awan, Atif, Bakkaloglu, Sevcan A., Baskin, Esra, Bekassy, Zivile, Bhimma, Rajendra, Bitzan, Martin, Bjerre, Anna Kristina, Bootsma‐Robroeks, Charlotte M., Bouts, Antonia, Büscher, Anja, Bulum, Burcu, Christian, Martin, Cicek, Neslihan, Clothier, Joanna, Cornelissen, Marlies, Dehoux, Laurène, Kılıç, Beltinge Demircioğlu, Dinçel, Nida Temizkan, Esfandiar, Nasrin, Espinosa‐Román, Laura, Fila, Marc, Galiano, Matthias, Gander, Romy, Gessner, Michaela, Grenda, Ryszard, Henne, Thomas, Herthelius, Maria, Goñi, Maria Herrero, Higueras, Walter, Hooman, Nakisa, Jahnukainen, Timo, Jankauskiene, Augustina, Jong, Huib, Knops, Noël, Konrad, Martin, Levtchenko, Elena, Madrid‐Aris, Alvaro, Marks, Stephen D., Mattoo, Tej K., Maxted, Andrew, Melgosa‐Hijosa, Marta, Mincham, Christine Marie, Mitsioni, Andromachi, Montini, Giovanni, Morgan, Henry, Müller‐Sacherer, Thomas, Murer, Luisa, Özçakar, Z Birsin, Pape, Lars, Parvex, Paloma, Printza, Nikoleta, Prytula, Agnieszka, Reynolds, Ben, Roussinov, Dimitar, Rubik, Jacek, Rumyantsev, Alexander, Rus, Rina, Seeman, Tomas, Shenoy, Mohan, Silva, Ana Cristina Simões E., Sinha, Rajiv, Stabouli, Stella, Taşdemir, Mehmet, Tasic, Velibor, Teixeira, Ana, Thumfart, Julia, Topaloğlu, Rezan, Torres, Diletta, Trnka, Peter, Tschumi, Sibylle, Tse, Yincent, Aki, Fazil Tuncay, Verrina, Enrico Eugenio, Vidal, Enrico, Weber, Lutz T., Yalçınkaya, Fatma Fatoş, Yap, Yok‐Chin, Yıldız, Nurdan, Yüksel, Selçuk, Zieg, Jakub

Source: Pediatric transplantation. 27(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175337682.0x000001&indx=1&recIds=ETOCvdc_100175337682.0x000001

Epidemiology and clinicopathological characteristics of native kidney disease in children in Flanders, Belgium.

Authors: Deleersnijder, Dries^1,2 dries.deleersnijder@kuleuven.be, Knops, Noël^3,4, Trouet, Dominique^5,6, Van Hoeck, Koen⁶, Karamaria, Sevasti^7,8, Vande Walle, Johan^7,8, Mauel, Reiner⁹, Cools, Louise¹, Meeus, Gert¹⁰, Dendooven, Amélie^5,11, De Meester, Johan¹², Laurens, Wim^7,12, Sprangers, Ben^1,2 ben.sprangers@zol.be

Source: Pediatric Nephrology. May2023, Vol. 38 Issue 5, p1533-1545. 13p. 2 Diagrams, 3 Charts, 4 Graphs.

Subject Terms: *KIDNEY disease diagnosis, *KIDNEY disease risk factors, *GLOMERULAR filtration rate, *KIDNEYS, *BIOPSY, *AGE distribution, *KIDNEY diseases, *SEVERITY of illness index, *SEX distribution, *RESEARCH funding, *DIAGNOSIS, *DESCRIPTIVE statistics, *DISEASE prevalence, *URINARY organ diseases, *GENETIC techniques, *SYMPTOMS, *CHILDREN

Geographic Terms: BELGIUM

Repeated kidney re‐transplantation—the Eurotransplant experience: a retrospective multicenter outcome analysis

Authors: Assfalg, Volker, Selig, Katharina, Tolksdorf, Johanna, Meel, Marieke, Vries, Erwin, Ramsoebhag, Anne‐Marie, Rahmel, Axel, Renders, Lutz, Novotny, Alexander, Matevossian, Edouard, Schneeberger, Stefan, Rosenkranz, Alexander R., Berlakovich, Gabriela, Ysebaert, Dirk, Knops, Noël, Kuypers, Dirk, Weekers, Laurent, Muehlfeld, Anja, Rump, Lars‐Christian, Hauser, Ingeborg, Pisarski, Przemyslaw, Weimer, Rolf, Fornara, Paolo, Fischer, Lutz, Kliem, Volker, Sester, Urban, Stippel, Dirk, Arns, Wolfgang, Hau, Hans‐Michael, Nitschke, Martin, Hoyer, Joachim, Thorban, Stefan, Weinmann‐Menke, Julia, Heller, Katharina, Banas, Bernhard, Schwenger, Vedat, Nadalin, Silvio, Lopau, Kai, Hüser, Norbert, Heemann, Uwe

Source: Transplant international. 33(6):617-631

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107735791.0x000001&indx=1&recIds=ETOCvdc_100107735791.0x000001

Connective tissue growth factor (CTGF) from basics to clinics

Authors: Ramazani, Yasaman, Knops, Noël, Elmonem, Mohamed A., Nguyen, Tri Q., Arcolino, Fanny Oliveira, van den Heuvel, Lambert, Levtchenko, Elena, Kuypers, Dirk, Goldschmeding, Roel

Source: In Matrix Biology August 2018 68-69:44-66

Effects of fecal microbiota transplantation for recurrent Clostridium difficile infection in children on kidney replacement therapy: a pilot study.

Authors: Samaey, An, Vázquez-Castellanos, Jorge Francisco, Caenepeel, Clara, Evenepoel, Pieter, Vermeire, Séverine, Raes, Jeroen, Knops, Noël

Source: Pediatric Nephrology; Apr2024, Vol. 39 Issue 4, p1201-1212, 12p

Subject Terms: FECAL analysis, NEPHROTIC syndrome diagnosis, THERAPEUTICS, PILOT projects, CHRONIC kidney failure, DIARRHEA, INFLAMMATION, GUT microbiome, CLOSTRIDIOIDES difficile, UREMIA, RENAL replacement therapy, VANCOMYCIN, PEDIATRICS, TREATMENT effectiveness, METRONIDAZOLE, VOMITING, CASE studies, DESCRIPTIVE statistics, INTESTINAL diseases, RESEARCH funding, FECAL microbiota transplantation, ALTERNATIVE medicine, BLOOD testing, BACTERIAL diseases, HEMODIALYSIS, ABDOMINAL pain, TOXINS, CHILDREN

Renal Replacement Therapy in children with severe developmental disability: guiding questions for decision-making

Authors: Willem, Lore, Knops, Noël, Mekahli, Djalila, Cochat, Pierre, Edefonti, Alberto, Verrina, Enrico, Groothoff, Jaap, Lagae, Lieven, Pirenne, Jacques, Dobbels, Fabienne, Borry, Pascal, Van Geet, Chris, Levtchenko, Elena

Source: European journal of pediatrics. 177(12):1735-1743

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125956146.0x000001&indx=1&recIds=ETOCvdc_100125956146.0x000001

A longitudinal study of long‐term renal outcome after pediatric liver transplantation in relation to CNI exposure.

Authors: Vandewiele, Simon, Herman, Jean, van den Heuvel, Lambert, Knops, Noël

Source: Pediatric Transplantation; Feb2024, Vol. 28 Issue 1, p1-10, 10p

Subject Terms: LIVER transplantation, CHRONIC kidney failure, LONGITUDINAL method, IMMUNOSUPPRESSIVE agents, TACROLIMUS

Rituximab in children with steroid-dependent nephrotic syndrome: experience of a tertiary center and review of the literature

Authors: Van Horebeek, Ilse, Knops, Noël, Van Dyck, Maria, Levtchenko, Elena, Mekahli, Djalila

Source: Acta clinica belgica. 72(3):147-155

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100048230165.0x000001&indx=1&recIds=ETOCvdc_100048230165.0x000001

Therapeutic concentrations of calcineurin inhibitors do not deregulate glutathione redox balance in human renal proximal tubule cells.

Authors: Ramazani, Yasaman¹ (AUTHOR), Knops, Noël^1,2 (AUTHOR), Berlingerio, Sante Princiero¹ (AUTHOR), Adebayo, Oyindamola Christiana¹ (AUTHOR), Lismont, Celien³ (AUTHOR), Kuypers, Dirk J.⁴ (AUTHOR), Levtchenko, Elena^1,2 (AUTHOR), van den Heuvel, Lambert P.^1,5 (AUTHOR), Fransen, Marc³ (AUTHOR) marc.fransen@kuleuven.be

Source: PLoS ONE. 4/30/2021, Vol. 16 Issue 4, p1-17. 17p.

Subject Terms: *PROXIMAL kidney tubules, *GLUTATHIONE, *GREEN fluorescent protein, *CALCINEURIN, *OXIDATION-reduction reaction, *OXIDATIVE stress

Bortezomib for autoimmune hemolytic anemia after intestinal transplantation.

Authors: Knops, Noël^1,2 (AUTHOR) Noel.knops@uzleuven.be, Emonds, Marie‐Paule^3,4 (AUTHOR), Herman, Jean^1,2 (AUTHOR), Levtchenko, Elena^1,2 (AUTHOR), Mekahli, Djalila^1,2 (AUTHOR), Pirenne, Jacques^5,6 (AUTHOR), Van Geet, Chris^7,8 (AUTHOR), Dierickx, Daan^9,10 (AUTHOR)

Source: Pediatric Transplantation. Jun2020, Vol. 24 Issue 4, p1-6. 6p.

Subject Terms: *BORTEZOMIB, *AUTOIMMUNE hemolytic anemia, *TRANSPLANTATION of organs, tissues, etc., *SHORT bowel syndrome, *LIVER enzymes

Time-Varying Determinants of Graft Failure in Pediatric Kidney Transplantation in Europe

Authors: Coens, Ferran, Knops, Noël, Tieken, Ineke, Vogelaar, Serge, Bender, Andreas, Kim, Jon Jin, Krupka, Kai, Pape, Lars, Raes, Ann, Tönshoff, Burkhard, Prytula, Agnieszka, Bald, M., Fehrenbach, H., Haffner, D., Hansen, M., Hempel, C., John, U., Klaus, G., König, J., Lange-Sperandio, B., Müller, D., Oh, J., Pape, L., Pohl, M., Sauerstein, K., Schalk, G., Staude, H., Strotmann, P., Weber, L.T., Weitz, M., Berta, L., Heindl-Rusai, K.

Source: Clinical Journal of The American Society of Nephrology; March 2024, Vol. 19 Issue: 3 p345-354, 10p

The Functional Implications of Common Genetic Variation in CYP3A5 and ABCB1 in Human Proximal Tubule Cells

Authors: Knops, Noël, van den Heuvel, Lambertus P., Masereeuw, Rosalinde, Bongaers, Inge, de Loor, Henriëtte, Levtchenko, Elena, Kuypers, Dirk

Source: Molecular pharmaceutics. 12(3):758-768

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN600428504&indx=1&recIds=ETOCRN600428504

Investigating Tacrolimus Disposition in Paediatric Patients with a Physiologically Based Pharmacokinetic Model Incorporating CYP3A4 Ontogeny, Mechanistic Absorption and Red Blood Cell Binding.

Authors: Van der Veken, Matthias, Brouwers, Joachim, Ozbey, Agustos Cetin, Umehara, Kenichi, Stillhart, Cordula, Knops, Noël, Augustijns, Patrick, Parrott, Neil John

Source: Pharmaceutics; Sep2023, Vol. 15 Issue 9, p2231, 21p

Subject Terms: CHILD patients, CYTOCHROME P-450 CYP3A, TACROLIMUS, ONTOGENY, DRUG monitoring, ERYTHROCYTE membranes, BLOOD plasma, ERYTHROCYTES

Illness-related parental stress and quality of life in children with kidney diseases.

Authors: De Bruyne, Elke, Willem, Lore, Van Hoeck, Koen, Reynaert, Sarah, Vankerckhove, Sylvie, Adams, Brigitte, Leroi, Stéphanie, Collard, Laure, Michaux, Aline, Godefroid, Nathalie, Mekahli, Djalila, Knops, Noël, Eloot, Sunny, Raes, Ann, Walle, Johan Vande, Van Hoecke, Eline, Snauwaert, Evelien, Levtchenko, Elena

Source: Pediatric Nephrology; Aug2023, Vol. 38 Issue 8, p2719-2731, 13p, 3 Charts, 5 Graphs

Subject Terms: PARENT attitudes, HYPERTENSION, INTERDISCIPLINARY research, NEPHROTIC syndrome, KIDNEY transplantation, ATTITUDES toward illness, KIDNEY diseases, METABOLIC disorders, QUALITY of life, RESEARCH funding, QUESTIONNAIRES, PROTEINURIA, PSYCHOLOGICAL stress, CHILDREN

Abnormal teeth and renal calcifications: Answers.

Authors: Therssen, Lore, Lambrecht, Loes, Vansteenkiste, Griet, Knops, Noël

Source: Pediatric Nephrology; Aug2023, Vol. 38 Issue 8, p2603-2610, 8p, 5 Charts

Subject Terms: AMELOGENESIS imperfecta, MEDICAL screening, DIFFERENTIAL diagnosis, KIDNEY calcification, URINALYSIS, URINARY calculi

Lessons for the clinical nephrologist: an unusual cause of isolated proteinuria in a child with Familial Mediterranean Fever.

Authors: Vanden Eynde, Nathalie, Koshy, Priyanka, De Somer, Lien, Knops, Noël

Source: Journal of Nephrology (JNonline); Jul2023, Vol. 36 Issue 6, p1699-1702, 4p

Oseltamivir Dosing in Children Undergoing Hemodialysis

Authors: Schreuder, Michiel F., van der Flier, Michiel, Knops, Noël B., Koster-Kamphuis, Linda, Brüggemann, Roger J.

Source: Clinical Infectious Diseases, 2010 May 01. 50(10), 1427-1428.

Access URL: https://www.jstor.org/stable/40599173

Tacrolimus induces a pro-fibrotic response in donor-derived human proximal tubule cells dependent on common variants of the CYP3A5 and ABCB1 genes.

Authors: Knops, Noël^1,2 (AUTHOR) noel.knops@uzleuven.be, Ramazani, Yasaman² (AUTHOR), Loor, Henriëtte De³ (AUTHOR), Goldschmeding, Roel⁴ (AUTHOR), Nguyen, Tri Q⁴ (AUTHOR), Heuvel, Lambert P van den^2,5 (AUTHOR), Levtchenko, Elena^1,2 (AUTHOR), Kuypers, Dirk J³ (AUTHOR)

Source: Nephrology Dialysis Transplantation. Mar2023, Vol. 38 Issue 3, p599-609. 11p.

Subject Terms: *EFFLUX (Microbiology), *CONNECTIVE tissue growth factor, *CYTOCHROME P-450 CYP3A, *P-glycoprotein, *TACROLIMUS, *RENAL fibrosis