Targeting of the Tec Kinase ITK Drives Resolution of T Cell–Mediated Colitis and Emerges as Potential Therapeutic Option in Ulcerative Colitis

Authors: Lechner, Kristina, Mott, Stefanie, Al-Saifi, Ragheed, Knipfer, Lisa, Wirtz, Stefan, Atreya, Raja, Vieth, Michael, Rath, Timo, Fraass, Tina, Winter, Zoltan, August, Avery, Luban, Jeremy, Zimmermann, Valérie S., Weigmann, Benno, Neurath, Markus F.

Source: In Gastroenterology October 2021 161(4):1270-1287

Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss

Authors: Omata, Yasunori, Frech, Michael, Lucas, Sébastien, Primbs, Tatjana, Knipfer, Lisa, Wirtz, Stefan, Kadono, Yuho, Saito, Taku, Tanaka, Sakae, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

Source: In Bone July 2020 136

A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2—mediated inflammation

Authors: Knipfer, Lisa, Schulz-Kuhnt, Anja, Kindermann, Markus, Greif, Vicky, Symowski, Cornelia, Voehringer, David, Neurath, Markus F., Atreya, Imke, Wirtz, Stefan

Source: Journal of experimental medicine. 216(12):2763-2777

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622359118&indx=1&recIds=ETOCRN622359118

Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2)

Authors: Koch, Sonja, Knipfer, Lisa, Kölle, Julia, Mirzakhani, Hooman, Graser, Anna, Zimmermann, Theodor, Kiefer, Alexander, Melichar, Volker, Rascher, Wolfgang, Papadopoulos, Nikolaos, Rieker, Ralf, Raby, Benjamin, Weiss, Scott, Wirtz, Stefan, Finotto, Susetta

Source: Scientific reports. 9(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190884837.0x000001&indx=1&recIds=ETOCvdc_100190884837.0x000001

ILC2s in infectious diseases and organ-specific fibrosis

Authors: Kindermann, Markus, Knipfer, Lisa, Atreya, Imke, Wirtz, Stefan

Source: Seminars in immunopathology. 40(4):379-392

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125508717.0x000001&indx=1&recIds=ETOCvdc_100125508717.0x000001

Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis

Authors: Azizov, Vugar, Dietel, Katharina, Steffen, Franziska, Dürholz, Kerstin, Meidenbauer, Julia, Lucas, Sébastien, Frech, Michael, Omata, Yasunori, Tajik, Narges, Knipfer, Lisa, Kolenbrander, Anne, Seubert, Silvia, Lapuente, Dennis, Sokolova, Maria V., Hofmann, Jörg, Tenbusch, Matthias, Ramming, Andreas, Steffen, Ulrike, Nimmerjahn, Falk, Linker, Ralf, Wirtz, Stefan, Herrmann, Martin, Temchura, Vladimir, Sarter, Kerstin, Schett, Georg, Zaiss, Mario M.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174614431.0x000001&indx=1&recIds=ETOCvdc_100174614431.0x000001

ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure.

Authors: Schulz-Kuhnt, Anja, Greif, Vicky, Hildner, Kai, Knipfer, Lisa, Döbrönti, Michael, Zirlik, Sabine, Fuchs, Florian, Atreya, Raja, Zundler, Sebastian, López-Posadas, Rocío, Neufert, Clemens, Ramming, Andreas, Kiefer, Alexander, Grüneboom, Anika, Strasser, Erwin, Wirtz, Stefan, Neurath, Markus F., Atreya, Imke

Source: Frontiers in Immunology; 5/7/2020, Vol. 11, p1-19, 19p

Subject Terms: CYSTIC fibrosis, RESPIRATORY insufficiency, INNATE lymphoid cells, PNEUMONIA, TISSUE remodeling, BRONCHIECTASIS, PULMONARY eosinophilia

An in vivo gene delivery approach for the isolation of reasonable numbers of type 2 innate lymphoid cells

Authors: Frech, Michael, Knipfer, Lisa, Wirtz, Stefan, Zaiss, Mario M.

Source: In MethodsX 2020 7

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