Deoxyestrone-based lipofection agents with solution- and solid-state emission propertiesElectronic supplementary information (ESI) available: Synthetic procedures, transfection, toxicity, photophysical characterisation, TEM and selected spectra. See DOI: https://doi.org/10.1039/d3ob00656e

Authors: Huber, Alexander, Koch, Johannes, Rudolph, Kevin, Höing, Alexander, Rizzo, Fabio, Knauer, Shirley K., Voskuhl, Jens

Source: Organic & biomolecular chemistry. 21(28):5762-5767

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187258038.0x000001&indx=1&recIds=ETOCvdc_100187258038.0x000001

Recognition of a Flexible Protein Loop in Taspase 1 by Multivalent Supramolecular Tweezers

Authors: Höing, Alexander, Kirupakaran, Abbna, Beuck, Christine, Pörschke, Marius, Niemeyer, Felix C., Seiler, Theresa, Hartmann, Laura, Bayer, Peter, Schrader, Thomas, Knauer, Shirley K.

Source: Biomacromolecules. 23(11):4504-4518

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632326165&indx=1&recIds=ETOCRN632326165

Dual activity inhibition of threonine aspartase 1 by a single bisphosphate ligandElectronic supplementary information (ESI) available: Chemical and biological assays, computational studies and microscopy, supporting figures and tables. See DOI: https://doi.org/10.1039/d2ra06019a

Authors: Höing, Alexander, Struth, Robin, Beuck, Christine, Rafieiolhosseini, Neda, Hoffmann, Daniel, Stauber, Roland H., Bayer, Peter, Niemeyer, Jochen, Knauer, Shirley K.

Source: RSC advances. 12(53):34176-34184

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167466638.0x000001&indx=1&recIds=ETOCvdc_100167466638.0x000001

Stepwise Modulation of Bridged Single‐Benzene‐Based Fluorophores for Materials Science.

Authors: Huber, Alexander¹, Schmidt, Laura², Gatz, Tim¹, Bublitz, Jana¹, Rex, Tobias³, Sailaja, Sidharth Thulaseedharen Nair¹, Verheggen, Elisabeth¹, Höfmann, Lea¹, Wölper, Christoph⁴, Strassert, Cristian A.³, Knauer, Shirley K.², Voskuhl, Jens¹, jens.voskuhl@uni-due.de

Source: Chemistry - A European Journal; 3/6/2025, Vol. 31 Issue 14, p1-10, 10p

The Taspase1/Myosin1f-axis regulates filopodia dynamics

Authors: Hensel, Astrid ^{1, 5, 6, ∗}, Stahl, Paul ^{1, 5}, Moews, Lisa ¹, König, Lena ¹, Patwardhan, Rutuja ², Höing, Alexander ¹, Schulze, Nina ³, Nalbant, Perihan ², Stauber, Roland H. ⁴, Knauer, Shirley K. ^{1, ∗∗}

Source: In iScience 17 June 2022 25(6)

Umbelliferone Decorated Water‐soluble Zinc(II) Phthalocyanines – In Vitro Phototoxic Antimicrobial Anti‐cancer Agents

Authors: Sowa, Andrea, Höing, Alexander, Dobrindt, Ulrich, Knauer, Shirley K., Galstyan, Anzhela, Voskuhl, Jens

Source: Chemistry. 27(59):14672-14680

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132969376.0x000001&indx=1&recIds=ETOCvdc_100132969376.0x000001

Luminescent Amphiphilic Aminoglycoside Probes to Study Transfection

Authors: Zimmermann, Alexander, Jaber, Qais Z., Koch, Johannes, Riebe, Steffen, Vallet, Cecilia, Loza, Kateryna, Hayduk, Matthias, Steinbuch, Kfir B., Knauer, Shirley K., Fridman, Micha, Voskuhl, Jens

Source: Chembiochem. 22(9):1563-1567

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121023249.0x000001&indx=1&recIds=ETOCvdc_100121023249.0x000001

PEGylated sequence-controlled macromolecules using supramolecular binding to target the Taspase1/Importin α interactionElectronic supplementary information (ESI) available. See DOI: 10.1039/d0cc07139k

Authors: Pasch, Peter, Höing, Alexander, Ueclue, Serap, Killa, Matthias, Voskuhl, Jens, Knauer, Shirley K., Hartmann, Laura

Source: Chemical communications. 57(25):3091-3094

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117385332.0x000001&indx=1&recIds=ETOCvdc_100117385332.0x000001

Synergetic Enhancing Effects between Platinum Nanosensitizers and Clinically Approved Stabilizing Ligands in Proton Therapy, Causing High‐Yield Double‐Strand Breaks of Plasmid DNA at Relevant Dose.

Authors: Zwiehoff, Sandra, Hensel, Astrid, Rishmawi, Ramin, Shakibaei, Parisa, Behrends, Carina, Hommel, Katrin, Bäumer, Christian, Knauer, Shirley Karin, Timmermann, Beate, Rehbock, Christoph, Barcikowski, Stephan

Source: Advanced Nanobiomed Research; Nov2024, Vol. 4 Issue 11, p1-15, 15p

Subject Terms: POLYETHYLENE glycol, REACTIVE oxygen species, LIGANDS (Biochemistry), PROTON therapy, SERUM albumin

Old Passengers as New Drivers: Chromosomal Passenger Proteins Engage in Translesion Synthesis.

Authors: Falke, Katharina, Schröder, Elisabeth, Mosel, Stefanie, Yürük, Cansu N., Feldmann, Sophie, Gül, Désirée, Stahl, Paul, Stauber, Roland H., Knauer, Shirley K.

Source: Cells (2073-4409); Nov2024, Vol. 13 Issue 21, p1804, 24p

Subject Terms: AURORA kinases, PROLIFERATING cell nuclear antigen, REPLICATION fork, CHROMOSOMAL proteins, SURVIVIN (Protein), DNA polymerases

Merging of a Supramolecular Ligand with a Switchable Luminophore – Light‐Responsiveness, Photophysics and Bioimaging.

Authors: Balszuweit, Jan¹, Stahl, Paul², Cappellari, Victoria³, Lorberg, Rick Y.¹, Wölper, Christoph⁴, Niemeyer, Felix C.¹, Koch, Johannes⁵, Prymak, Oleg⁴, Knauer, Shirley K.², Strassert, Cristian A.³, Voskuhl, Jens¹, jens.voskuhl@uni-due.de

Source: Chemistry - A European Journal; 10/11/2024, Vol. 30 Issue 57, p1-9, 9p

Functional Linkers Support Targeting of Multivalent Tweezers to Taspase1.

Authors: Hommel, Katrin¹, Kauth, Alisa‐Maite A.², Kirupakaran, Abbna³, Theisen, Sebastian³, Hayduk, Matthias⁴, Niemeyer, Felix C.³, Beuck, Christine⁵, Zadmard, Reza⁶, Bayer, Peter⁵, Jan Ravoo, Bart², Voskuhl, Jens⁴, jens.voskuhl@uni-due.de, Schrader, Thomas³, thomas.schrader@uni-due.de, Knauer, Shirley K.¹, shirley.knauer@uni-due.de

Source: Chemistry - A European Journal; 10/8/2024, Vol. 30 Issue 56, p1-11, 11p

Tuning Nanobodies' Bioactivity: Coupling to Ultrasmall Gold Nanoparticles Allows the Intracellular Interference with Survivin

Authors: Stahl, Paul, Kollenda, Sebastian, Sager, Jonas, Schmidt, Laura, Schroer, Martin A., Stauber, Roland H., Epple, Matthias, Knauer, Shirley K.

Source: Small. 19(33)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190313409.0x000001&indx=1&recIds=ETOCvdc_100190313409.0x000001

A Fluorophore‐Labeled Lysine Dendrimer with an Oxo‐Anion‐Binding Motif for Tracking Gene Transfection

Authors: Aldemir, Nazli, Vallet, Cecilia, Knauer, Shirley K., Schmuck, Carsten, Hirschhäuser, Christoph

Source: Chembiochem. 24(15)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189905149.0x000001&indx=1&recIds=ETOCvdc_100189905149.0x000001

Cationic Solution and Solid‐State Emitters – Robust Imaging Agents for Cells, Bacteria, and Protists

Authors: Dubbert, Justin, Höing, Alexander, Graupner, Nadine, Rajter, Ľubomír, Dunthorn, Micah, Knauer, Shirley K., Galstyan, Anzhela, Rizzo, Fabio, Voskuhl, Jens

Source: Chemistry. 29(38)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186836594.0x000001&indx=1&recIds=ETOCvdc_100186836594.0x000001

Impact of Peptide Sequences on Their Structure and Function: Mimicking of Virus‐Like Nanoparticles for Nucleic Acid Delivery

Authors: Jana, Poulami, Samanta, Krishnananda, Ehlers, Martin, Zellermann, Elio, Bäcker, Sandra, Stauber, Roland H., Schmuck, Carsten, Knauer, Shirley K.

Source: Chembiochem. 24(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182463520.0x000001&indx=1&recIds=ETOCvdc_100182463520.0x000001

Supramolecular subphthalocyanine complexes–cellular uptake and phototoxicityElectronic supplementary information (ESI) available: Synthesis, NMR- and mass spectra, photophysical characterisation, NMR titrations, fluorescence microscopy, phototoxiycity. See DOI: 10.1039/d0cc03065a

Authors: DubbertThese authors contributed equally., Justin, Höing, Alexander, Riek, Nathalie, Knauer, Shirley K., Voskuhl, Jens

Source: Chemical communications. 56(55):7653-7656

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117349202.0x000001&indx=1&recIds=ETOCvdc_100117349202.0x000001

Boosting nanotoxicity to combat multidrug-resistant bacteria in pathophysiological environmentsElectronic supplementary information (ESI) available. See DOI: 10.1039/d0na00644k

Authors: Westmeier, Dana, Siemer, Svenja, Vallet, Cecilia, Steinmann, Jörg, Docter, Dominic, Buer, Jan, Knauer, Shirley K., Stauber, Roland H.

Source: Nanoscale advances. 2(11):5428-5440

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110477975.0x000001&indx=1&recIds=ETOCvdc_100110477975.0x000001

The other side of the corona: nanoparticles inhibit the protease taspase1 in a size-dependent mannerElectronic supplementary information (ESI) available. See DOI: 10.1039/d0nr01631d

Authors: van den Boom, Johannes, Hensel, Astrid, Trusch, Franziska, Matena, Anja, Siemer, Svenja, Guel, Désirée, Docter, Dominic, Höing, Alexander, Bayer, Peter, Stauber, Roland H., Knauer, Shirley K.

Source: Nanoscale. 12(37):19093-19103

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100110479763.0x000001&indx=1&recIds=ETOCvdc_100110479763.0x000001

Funktionelle Inhibition der krebsrelevanten Interaktion von Survivin und Histon H3 mit einem Guanidiniumcarbonylpyrrol‐Liganden

Authors: Vallet, Cecilia, Aschmann, Dennis, Beuck, Christine, Killa, Matthias, Meiners, Annika, Mertel, Marcel, Ehlers, Martin, Bayer, Peter, Schmuck, Carsten, Giese, Michael, Knauer, Shirley K.

Source: Angewandte Chemie. 132(14):5614-5619

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109028594.0x000001&indx=1&recIds=ETOCvdc_100109028594.0x000001