Restoration of angiogenic capacity in senescent endothelial cells by a pharmacological reprogramming approach.

Authors: Kalies, Katrin¹ (AUTHOR) kai.knoepp@ul-halle.de, Knöpp, Kai¹ (AUTHOR) kai.knoepp@ul-halle.de, Koch, Susanne¹ (AUTHOR), Pilowski, Claudia¹ (AUTHOR), Wurmbrand, Leonie¹ (AUTHOR), Sedding, Daniel¹ (AUTHOR)

Source: PLoS ONE. 2/28/2025, Vol. 20 Issue 2, p1-21. 21p.

Subject Terms: *ENDOTHELIAL cells, *CELL physiology, *CAPACITY (Law), *DNA damage, *VASCULAR diseases, *NEOVASCULARIZATION

Isolation of circulating endothelial cells provides tool to determine endothelial cell senescence in blood samples.

Authors: Kalies, Katrin¹ (AUTHOR) katrin.kalies@uk-halle.de, Knöpp, Kai¹ (AUTHOR), Wurmbrand, Leonie¹ (AUTHOR), Korte, Laura² (AUTHOR), Dutzmann, Jochen¹ (AUTHOR), Pilowski, Claudia¹ (AUTHOR), Koch, Susanne¹ (AUTHOR), Sedding, Daniel¹ (AUTHOR)

Source: Scientific Reports. 2/24/2024, Vol. 14 Issue 1, p1-13. 13p.

Subject Terms: *ENDOTHELIAL cells, *BLOOD cells, *OLDER patients, *BLOOD sampling, *CELL morphology

BET bromodomain-containing epigenetic reader proteins regulate vascular smooth muscle cell proliferation and neointima formation

Authors: Dutzmann, Jochen, Haertlé, Marco, Daniel, Jan-Marcus, Kloss, Frederik, Musmann, Robert-Jonathan, Kalies, Katrin, Knöpp, Kai, Pilowski, Claudia, Sirisko, Mirja, Sieweke, Jan-Thorben, Bauersachs, Johann, Sedding, Daniel G, Gegel, Simona

Source: Cardiovascular research. 117(3):850-862

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130286641.0x000001&indx=1&recIds=ETOCvdc_100130286641.0x000001

The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation

Authors: Fu, Hang, Alabdullah, Mohamad, Großmann, Julia, Spieler, Florian, Abdosh, Reem, Lutz, Veronika, Kalies, Katrin, Knöpp, Kai, Rieckmann, Max, Koch, Susanne, Noutsias, Michel, Pilowski, Claudia, Dutzmann, Jochen, Sedding, Daniel, Hüttelmaier, Stefan, Umezawa, Kazuo, Werdan, Karl, Loppnow, Harald

Source: Cell death and disease. 10(12):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191087622.0x000001&indx=1&recIds=ETOCvdc_100191087622.0x000001

Intermittent Fasting After ST-Segment--Elevation Myocardial Infarction Improves Left Ventricular Function: The Randomized Controlled INTERFAST-MI Trial.

Authors: Dutzmann, Jochen, Kefalianakis, Zoe, Kahles, Florian, Daniel, Jan-Marcus, Gufler, Hubert, Wohlgemuth, Walter Alexander, Knöpp, Kai, Sedding, Daniel G.

Source: Circulation: Heart Failure; May2024, Vol. 17 Issue 5, p403-412, 10p

BET bromodomain-containing epigenetic reader proteins regulate vascular smooth muscle cell proliferation and neointima formation.

Authors: Dutzmann, Jochen, Haertlé, Marco, Daniel, Jan-Marcus, Kloss, Frederik, Musmann, Robert-Jonathan, Kalies, Katrin, Knöpp, Kai, Pilowski, Claudia, Sirisko, Mirja, Sieweke, Jan-Thorben, Bauersachs, Johann, Sedding, Daniel G, Gegel, Simona

Source: Cardiovascular Research; Mar2021, Vol. 117 Issue 3, p850-862, 13p

Subject Terms: VASCULAR smooth muscle, FORKHEAD transcription factors, MUSCLE cells, CELL proliferation, LABORATORY mice

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miR-148a-3p: A novel therapeutic candidate modulating angiogenesis and senescence for enhanced myocardial infarction recovery – experimental insights and targets explored.

Authors: Hehl, Laura¹ (AUTHOR), Kalies, Katrin¹ (AUTHOR), Daniel, Fiene¹ (AUTHOR), Köster, Jan Michael¹ (AUTHOR), Gürlach, Simon¹ (AUTHOR), Knöpp, Kai¹ (AUTHOR), Dutzmann, Jochen¹ (AUTHOR), Hinkel, Rabea² (AUTHOR), Sedding, Daniel¹ (AUTHOR)

Source: Atherosclerosis (00219150). 2024 Supplement 1, Vol. 395, pN.PAG-N.PAG. 1p.

Subject Terms: *MYOCARDIAL infarction, *NEOVASCULARIZATION